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Angewandte Chemie (International ed.), ISSN 1433-7851, 10/2016, Volume 55, Issue 43, pp. 13524 - 13528
.... Moreover, compared with known anti‐cancer ruthenium complexes, Ru‐1 is distinct in that it suppressed the expression of vascular endothelial growth factor receptor‐2 (VEGFR2... 
ruthenium | VEGFRs | anti-cancer | angiogenesis | VITRO | SIGNALING PATHWAYS | METASTASIS | ORGANOMETALLIC COMPLEXES | CANCER | CHEMISTRY, MULTIDISCIPLINARY | NAMI-A | ARENE COMPLEXES | ANTICANCER DRUGS | CELL | BINDING | Macrocyclic Compounds - chemistry | Humans | Structure-Activity Relationship | Ruthenium - chemistry | Macrocyclic Compounds - pharmacology | Neovascularization, Pathologic - pathology | Dose-Response Relationship, Drug | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Mammary Neoplasms, Experimental - pathology | Coordination Complexes - pharmacology | Female | Antineoplastic Agents - pharmacology | Mammary Neoplasms, Experimental - drug therapy | Human Umbilical Vein Endothelial Cells - drug effects | Angiogenesis Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Zebrafish | Antineoplastic Agents - chemistry | Down-Regulation - drug effects | Coordination Complexes - chemistry | Ruthenium - pharmacology | Animals | Mice, Nude | Neovascularization, Pathologic - drug therapy | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Angiogenesis Inhibitors - chemistry | Drug Screening Assays, Antitumor | Ruthenium | Endothelial growth factors | Analysis | Cancer | Angiogenesis | Vascular endothelial growth factor | Rodents | Biotechnology | Cytotoxicity | Tumor cell lines | Vascular endothelial growth factor receptors | Down-regulation | Xenografts | Inhibition
Journal Article
Nature (London), ISSN 1476-4687, 2014, Volume 517, Issue 7536, pp. 612 - 615
Pathogenic mycobacteria induce the formation of complex cellular aggregates called granulomas that are the hallmark of tuberculosis(1,2). Here we examine the... 
ZEBRAFISH | TUBERCULOSIS | VEGF | MULTIDISCIPLINARY SCIENCES | MACROPHAGE | TISSUE | TUMOR | INFECTION | METRONIDAZOLE | INHIBITOR | GRANULOMA | Granuloma - metabolism | Tuberculosis - microbiology | Hypoxia - microbiology | Vascular Endothelial Growth Factor A - metabolism | Zebrafish - microbiology | Mycobacterium marinum - pathogenicity | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Bacterial Load - drug effects | Hypoxia - metabolism | Mycobacterium Infections, Nontuberculous - pathology | Receptors, Vascular Endothelial Growth Factor - metabolism | Larva - drug effects | Mycobacterium Infections, Nontuberculous - microbiology | Tuberculosis - drug therapy | Angiogenesis Inhibitors - therapeutic use | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Mycobacterium marinum - growth & development | Macrophages - microbiology | Neovascularization, Pathologic - microbiology | Disease Models, Animal | Mycobacterium marinum - drug effects | Tuberculosis - pathology | Granuloma - microbiology | Macrophages - pathology | Angiogenesis Inhibitors - pharmacology | Antibiotics, Antitubercular - pharmacology | Zebrafish - growth & development | Drug Synergism | Granuloma - pathology | Macrophages - metabolism | Animals | Signal Transduction - drug effects | Hypoxia - pathology | Neovascularization, Pathologic - drug therapy | Mycobacterium Infections, Nontuberculous - metabolism | Granuloma - drug therapy | Larva - microbiology | Mycobacterium Infections, Nontuberculous - drug therapy | Granuloma | Mycobacterium | Mycobacteria | Cellular signal transduction | Research | Drug therapy | Health aspects | Risk factors | Angiogenesis | Signal transduction | Zebrafish | Bacteria | Hypoxia | Infections | Gene expression | Drug dosages | Veins & arteries
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Development (Cambridge), ISSN 1477-9129, 2014, Volume 141, Issue 6, pp. 1239 - 1249
Journal Article