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The Journal of clinical investigation, ISSN 0021-9738, 2015, Volume 125, Issue 6, pp. 2375 - 2384
Journal Article
Annals of Neurology, ISSN 0364-5134, 12/2013, Volume 74, Issue 6, pp. 837 - 847
Journal Article
Journal of the American Society of Nephrology, ISSN 1533-3450, 2013, Volume 24, Issue 9, pp. 1435 - 1450
Journal Article
Blood, ISSN 0006-4971, 12/2008, Volume 112, Issue 13, pp. 5228 - 5237
Mutations in several ribosomal proteins (RPs) lead to Diamond-Blackfan anemia (DBA), a syndrome characterized by defective erythropoiesis, congenital anomalies, and increased frequency of cancer... 
ENCODES | TARGET | APOPTOSIS | STEM-CELLS | DIAMOND-BLACKFAN ANEMIA | MICE | GENE KNOCKDOWN | P63 | IDENTIFICATION | HEMATOLOGY | EXPRESSION | Ribosomal Proteins - deficiency | Animals | Tumor Suppressor Protein p53 - metabolism | Zebrafish | Anemia, Diamond-Blackfan | Phosphoproteins - physiology | Abnormalities, Multiple - genetics | Zebrafish Proteins - physiology | Erythropoiesis - genetics | Trans-Activators - physiology
Journal Article
Development (Cambridge), ISSN 1477-9129, 2014, Volume 141, Issue 6, pp. 1228 - 1238
In mammals, the homeodomain transcription factor Prox1 acts as the central regulator of lymphatic cell fate. Its restricted expression in a subset of cardinal... 
Endothelial Cells | Species Specificity | Animals, Genetically Modified | Zebrafish Proteins | Zebrafish | Mice, Knockout | Cell Lineage | Animals | Gene Expression Regulation, Developmental | Homeodomain Proteins | Lymphatic Vessels | Cell Differentiation | Mice | Mutation | SOXF Transcription Factors | Lymphangiogenesis | COUP Transcription Factor II | Tumor Suppressor Proteins | Prox1 | Coup-TFII | Nr2f2 | Sox18 | XENOPUS-LAEVIS | GROWTH-FACTOR-C | IN-VIVO | DEVELOPMENTAL BIOLOGY | VASCULAR ENDOTHELIAL-CELLS | TRANSCRIPTION FACTOR | REDUNDANT ROLES | SOXF Transcription Factors - metabolism | Lymphatic Vessels - metabolism | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | COUP Transcription Factor II - deficiency | Lymphatic Vessels - cytology | Endothelial Cells - metabolism | Zebrafish Proteins - metabolism | Lymphangiogenesis - physiology | Zebrafish - growth & development | Homeodomain Proteins - genetics | Zebrafish - genetics | Zebrafish Proteins - physiology | Tumor Suppressor Proteins - physiology | Zebrafish Proteins - deficiency | COUP Transcription Factor II - genetics | Endothelial Cells - cytology | Zebrafish - physiology | COUP Transcription Factor II - metabolism | Zebrafish Proteins - genetics | Homeodomain Proteins - physiology | SOXF Transcription Factors - deficiency | SOXF Transcription Factors - genetics | Lymphangiogenesis - genetics | Index Medicus | in-vivo | transcription factor | growth-factor-c | lymphangiogenesis | coup-tfii | prox1 | redundant roles | sox18 | xenopus-laevis | vascular endothelial-cells
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2014, Volume 71, Issue 1, pp. 234 - 244
Journal Article
PLoS genetics, ISSN 1553-7404, 2014, Volume 10, Issue 10, p. e1004688
Journal Article
Nature (London), ISSN 1476-4687, 2018, Volume 554, Issue 7690, pp. 112 - 117
Many craniofacial disorders are caused by heterozygous mutations in general regulators of housekeeping cellular functions such as transcription or ribosome... 
PATHOGENESIS | CELLS | PROTEIN | ENDONUCLEASE | RNA HELICASE DDX21 | DNA | MULTIDISCIPLINARY SCIENCES | PREVENTION | TREACHER-COLLINS-SYNDROME | NEURAL CREST | P53 | Xenopus | Chromatin - metabolism | Cell Nucleolus - pathology | Embryonic Stem Cells - cytology | Mandibulofacial Dysostosis - embryology | Humans | Protein Transport - drug effects | DNA-Directed RNA Polymerases - deficiency | RNA, Ribosomal - genetics | RNA Polymerase I - antagonists & inhibitors | Mandibulofacial Dysostosis - genetics | Cell Nucleus - metabolism | Skull - pathology | Nuclear Proteins - deficiency | Cell Nucleolus - drug effects | Stress, Physiological - drug effects | Neural Crest - enzymology | Benzothiazoles - pharmacology | Phenotype | Zebrafish Proteins - deficiency | Ribosomes - genetics | Mice | DNA Damage | HeLa Cells | Embryonic Stem Cells - metabolism | RNA Helicases - metabolism | Mandibulofacial Dysostosis - pathology | Neural Crest - pathology | Ribosomal Proteins - biosynthesis | Ribosomes - metabolism | DNA, Ribosomal - metabolism | Phosphoproteins - metabolism | Zebrafish - embryology | Cell Nucleus - pathology | Cell Nucleolus - metabolism | DEAD-box RNA Helicases - deficiency | DEAD-box RNA Helicases - metabolism | Nuclear Proteins - genetics | DNA, Ribosomal - genetics | Cell Nucleolus - genetics | Ribosomal Proteins - genetics | Tumor Suppressor Protein p53 - metabolism | RNA, Ribosomal - metabolism | Nuclear Proteins - metabolism | Phosphoproteins - genetics | Organ Specificity | DEAD-box RNA Helicases - genetics | Animals | Phosphoproteins - deficiency | RNA, Ribosomal - biosynthesis | Cell Nucleus - drug effects | Naphthyridines - pharmacology | Apoptosis | Nucleolus organizer region | Genetic aspects | Gene mutations | Observations | Neural crest | Craniofacial dysostosis | Chromatin | Transcription | Genomics | p53 Protein | Genes | DNA damage | Ribosomal DNA | Disorders | Homeostasis | Biosynthesis | Genomes | DNA-directed RNA polymerase | Proteins | DNA helicase | Nucleoli | Embryogenesis | Cell activation | RNA processing | Chemical synthesis | Deoxyribonucleic acid--DNA | Anemia | rRNA | RNA polymerase | Ribonucleic acid--RNA | Embryonic growth stage | DNA biosynthesis | Craniofacial growth | Stem cells | Mutation | Developmental disabilities | Tumors | RNA helicase
Journal Article
by Dai, W and Bai, Y and Hebda, L and Zhong, X and Liu, J and Kao, J and Duan, C
Cell death and differentiation, ISSN 1476-5403, 2013, Volume 21, Issue 4, pp. 568 - 581
Calcium deficiency causes abnormal colonic growth and increases colon cancer risk with poorly understood mechanisms... 
insulin-like growth factor binding protein 5 | transient receptor potential vanilloid | zebrafish | colon cancer cell | epithelial growth | membrane depolarization | IGF-BINDING-PROTEINS | UNITED-STATES | VITAMIN-D | ZEBRAFISH DANIO-RERIO | SENSING RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | DAIRY-PRODUCTS | PORE PROPERTIES | CELL BIOLOGY | COLON-CANCER | CA2+ CHANNEL | GROWTH-FACTOR | Receptor, IGF Type 1 - metabolism | Insulin-Like Growth Factor I - pharmacology | Receptor, IGF Type 1 - antagonists & inhibitors | Epithelial Cells - metabolism | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Epithelial Cells - drug effects | Humans | Oligonucleotides, Antisense - metabolism | Proto-Oncogene Proteins c-akt - genetics | Yolk Sac - cytology | TRPV Cation Channels - metabolism | TRPV Cation Channels - antagonists & inhibitors | Insulin-Like Growth Factor II - pharmacology | Epithelial Cells - cytology | Proto-Oncogene Proteins c-akt - metabolism | Phosphatidylinositol 3-Kinase - metabolism | Caco-2 Cells | Calcium - pharmacology | Zebrafish Proteins - metabolism | Zebrafish Proteins - antagonists & inhibitors | Receptor, IGF Type 1 - genetics | Zebrafish - growth & development | TRPV Cation Channels - genetics | Larva - cytology | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Phosphatidylinositol 3-Kinase - genetics | Signal Transduction - drug effects | Zebrafish - metabolism | Cell Proliferation - drug effects | Zebrafish Proteins - genetics | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Original Paper
Journal Article
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 06/2016, Volume 126, Issue 6, pp. 2167 - 2180
Lymphangiogenesis is supported by 2 homologous VEGFR3 ligands, VEGFC and VEGFD. VEGFC is required for lymphatic development, while VEGFD is not. VEGFC and... 
VASCULAR DEVELOPMENT | MEDICINE, RESEARCH & EXPERIMENTAL | EMBRYONIC LYMPHANGIOGENESIS | SKELETAL-MUSCLE | CCBE1 | LYMPHATIC VESSELS | FACTOR-C | TYROSINE KINASES | LIGAND | LYMPHEDEMA | ENDOTHELIAL GROWTH-FACTOR | Cell Proliferation | Humans | Vascular Endothelial Growth Factor D - deficiency | Vascular Endothelial Growth Factor C - deficiency | ADAMTS Proteins - deficiency | Lymphatic Vessels - metabolism | Procollagen N-Endopeptidase - metabolism | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | HEK293 Cells | Vascular Endothelial Growth Factor D - genetics | Peptide Hydrolases - metabolism | Calcium-Binding Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Signal Transduction | ADAMTS Proteins - metabolism | Endothelial Cells - metabolism | Procollagen N-Endopeptidase - genetics | Lymphangiogenesis - physiology | Calcium-Binding Proteins - deficiency | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Vascular Endothelial Growth Factor C - genetics | Mice, Knockout | Vascular Endothelial Growth Factor D - metabolism | Animals | Endothelial Cells - cytology | Models, Biological | Vascular Endothelial Growth Factor C - metabolism | Ligands | Mice | Lymphangiogenesis - genetics | ADAMTS Proteins - genetics | Calcium-Binding Proteins - genetics | Genetic aspects | Neovascularization | Proteolysis | Vascular endothelial growth factor | Health aspects | Studies | Lymphatic system | Lymphedema | Rodents | Cloning | Zebrafish | Skin | Experiments | Defects
Journal Article
Blood, ISSN 1528-0020, 2010, Volume 116, Issue 19, pp. 4025 - 4033
Sprouting of developing blood vessels is mediated by specialized motile endothelial cells localized at the tips of growing capillaries. Following behind the... 
VASCULAR DEVELOPMENT | ANGIOGENIC FACTOR | FACTOR-BETA | BASEMENT-MEMBRANE FORMATION | IN-VIVO | NETWORK FORMATION | UROKINASE RECEPTOR | APELIN | DEFICIENT MICE | HEMATOLOGY | INHIBITS TUMOR-GROWTH | Multigene Family | Oligonucleotide Array Sequence Analysis | Receptors, G-Protein-Coupled - metabolism | TOR Serine-Threonine Kinases - metabolism | Extracellular Matrix - metabolism | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Intracellular Signaling Peptides and Proteins - deficiency | Membrane Proteins - deficiency | Retinal Vessels - cytology | Membrane Proteins - metabolism | Capillaries - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Vascular Endothelial Growth Factor A - pharmacology | Apelin | Retinal Vessels - metabolism | Signal Transduction | Endothelial Cells - metabolism | Membrane Proteins - genetics | Neovascularization, Physiologic - genetics | Intercellular Signaling Peptides and Proteins | Mice, Inbred C57BL | Zebrafish | Adipokines | Capillaries - growth & development | Haploinsufficiency | Mice, Knockout | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Receptors, G-Protein-Coupled - deficiency | Capillaries - cytology | Endothelial Cells - cytology | Retinal Vessels - growth & development | Apelin Receptors | Mice | Receptors, G-Protein-Coupled - genetics | Endothelial Cells - drug effects | Vascular Biology
Journal Article