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Circulation, ISSN 0009-7322, 10/2014, Volume 130, Issue 15, pp. 1225 - 1235
BACKGROUND—Atrial fibrillation (AF) affects >30 million individuals worldwide and is associated with an increased risk of stroke, heart failure, and death. AF... 
Atrial fibrillation | Genetics | Zebrafish | Gene expression | Single nucleotide | Epidemiology | Polymorphism | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | METAANALYSIS | VARIANTS | polymorphism | LOCI | epidemiology | atrial fibrillation | PR INTERVAL | genetics | single nucleotide | PERIPHERAL VASCULAR DISEASE | PRAVASTATIN | zebrafish | HEART-RATE | ISCHEMIC-STROKE | gene expression | ONSET | GENOME-WIDE ASSOCIATION | T-Box Domain Proteins - physiology | Humans | Middle Aged | Male | Genetic Loci - physiology | Atrial Fibrillation - physiopathology | Ubiquitin-Protein Ligases - physiology | Gene Knockdown Techniques | Repressor Proteins - physiology | Muscle Proteins | Connexin 43 - physiology | Female | Nuclear Proteins - genetics | Connexin 43 - genetics | Transcription Factors - physiology | Europe | Japan | Repressor Proteins - genetics | Atrial Fibrillation - ethnology | Genotype | Chromosome Mapping | Transcription Factors - genetics | Atrial Fibrillation - genetics | T-Box Domain Proteins - genetics | Homeodomain Proteins - genetics | Zebrafish Proteins - physiology | Animals | Genetic Predisposition to Disease - ethnology | Aged | Nuclear Proteins - physiology | Zebrafish Proteins - genetics | Homeodomain Proteins - physiology | Quantitative Trait Loci | Ubiquitin-Protein Ligases - genetics | Stroke (Disease) | Care and treatment | Usage | Analysis | Genetic transcription | Diagnosis | Nucleotides | Risk factors | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2005, Volume 47, Issue 6, pp. 817 - 831
The molecular mechanisms controlling the differentiation of neural progenitors into distinct subtypes of neurons during neocortical development are unknown.... 
AREA IDENTITY | NEOCORTICAL NEURONS | CELL FATE SPECIFICATION | CEREBRAL CORTICAL DEVELOPMENT | LAYER NEURONS | CENTRAL-NERVOUS-SYSTEM | SUBCORTICAL TARGETS | ZINC-FINGER GENE | SUBVENTRICULAR ZONE | NEUROSCIENCES | ZEBRAFISH FOREBRAIN | Membrane Glycoproteins - metabolism | Embryo, Mammalian | Homeodomain Proteins - metabolism | Nerve Tissue Proteins - deficiency | S100 Proteins - genetics | POU Domain Factors - genetics | Forkhead Transcription Factors - metabolism | In Situ Hybridization - methods | Repressor Proteins - metabolism | Gene Expression Regulation, Developmental - physiology | POU Domain Factors - metabolism | Animals, Newborn | DNA-Binding Proteins - physiology | Motor Neurons - physiology | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cell Cycle Proteins - metabolism | S100 Proteins - metabolism | In Situ Nick-End Labeling - methods | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Immunohistochemistry - methods | Annexin A2 - genetics | Cell Death - physiology | Green Fluorescent Proteins - biosynthesis | Mice | Annexin A2 - metabolism | Age Factors | Phosphopyruvate Hydratase - metabolism | Cell Movement - physiology | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | Amino Acids - metabolism | Motor Neurons - cytology | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Membrane Proteins - metabolism | Bromodeoxyuridine - metabolism | Cell Differentiation - physiology | Pyramidal Tracts - physiology | Nerve Tissue Proteins - physiology | Neocortex - growth & development | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Dopamine and cAMP-Regulated Phosphoprotein 32 - metabolism | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Membrane Glycoproteins - genetics | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Cell Count - methods | Neocortex - cytology | Receptors, Antigen, T-Cell, alpha-beta - metabolism | Neurosciences | Neurons | Developmental biology | Stem cells | Studies | Brain | Ultrasonic imaging | Transcription factors | Hybridization | Neurogenesis | Index Medicus
Journal Article
Developmental Biology, ISSN 0012-1606, 12/2015, Volume 408, Issue 2, pp. 316 - 327
The planar cell polarity (PCP) pathway orients cells in diverse epithelial tissues in and vertebrate embryos and has been implicated in many human congenital... 
Xenopus | Vangl2 | Gastrulation | Multiciliated cells | KIF13B | Planar cell polarity | Disheveled | Prickle3 | Radial intercalation | DIVISION ORIENTATION | BRANCHING MORPHOGENESIS | DEVELOPMENTAL BIOLOGY | MUCOCILIARY EPIDERMIS | NEURAL-TUBE CLOSURE | PROTRUSIVE ACTIVITY | CONVERGENT EXTENSION MOVEMENTS | ZEBRAFISH GASTRULATION | APICAL CONSTRICTION | PLANAR POLARITY | Cilia - physiology | Xenopus Proteins - genetics | Humans | Neurulation - physiology | Epithelial Cells - physiology | Gastrulation - physiology | Gastrulation - genetics | Membrane Proteins - physiology | HEK293 Cells | Kinesin - genetics | Phosphoproteins - physiology | Xenopus laevis - genetics | Dishevelled Proteins | DNA-Binding Proteins - physiology | Xenopus laevis - embryology | Signal Transduction | Animals, Genetically Modified | Membrane Proteins - genetics | Neurulation - genetics | Phosphoproteins - genetics | DNA-Binding Proteins - genetics | Cilia - genetics | Cell Polarity - genetics | Cell Surface Extensions - genetics | Adaptor Proteins, Signal Transducing - physiology | Animals | Adaptor Proteins, Signal Transducing - genetics | Xenopus Proteins - physiology | Cell Polarity - physiology | LIM Domain Proteins - genetics | Kinesin - physiology | LIM Domain Proteins - physiology | Xenopus laevis - physiology | Cell Movement | Cell Surface Extensions - physiology | Proteins | Embryonic development | Birth defects | Genetic disorders | Amphibians | Protein binding | Index Medicus
Journal Article
Development (Cambridge), ISSN 0950-1991, 03/2014, Volume 141, Issue 6, pp. 1381 - 1391
How signaling gradients supply positional information in a field of moving cells is an unsolved question in patterning and morphogenesis. Here, we ask how a... 
Signal gradient | Wnt signaling | Embryonic elongation | Fgf signaling | Segmentation clock | Time-lapse microscopy | WAVE-FRONT ACTIVITY | SIGNALING PATHWAYS | MOUSE EMBRYOS | NOTCH | DEVELOPMENTAL BIOLOGY | BOUNDARY FORMATION | GENE-EXPRESSION | BODY FORMATION | PRESOMITIC MESODERM | VERTEBRATE SEGMENTATION | T-Box Domain Proteins - physiology | Fibroblast Growth Factors - genetics | Wnt Signaling Pathway - physiology | Zebrafish - embryology | Intercellular Signaling Peptides and Proteins - physiology | Somites - embryology | Wnt Proteins - genetics | Gene Expression Regulation, Developmental | Fibroblast Growth Factors - physiology | Somites - metabolism | Basic Helix-Loop-Helix Transcription Factors - physiology | Basic Helix-Loop-Helix Transcription Factors - genetics | Animals, Genetically Modified | Zebrafish Proteins - antagonists & inhibitors | Intercellular Signaling Peptides and Proteins - genetics | Heat-Shock Response - physiology | T-Box Domain Proteins - genetics | Zebrafish - genetics | Zebrafish Proteins - physiology | Body Patterning - physiology | Heat-Shock Response - genetics | Animals | Wnt Signaling Pathway - genetics | Models, Biological | Zebrafish - metabolism | Wnt Proteins - physiology | Zebrafish Proteins - genetics | Wnt Proteins - antagonists & inhibitors | Body Patterning - genetics | Index Medicus | Life Sciences | Genetics
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2010, Volume 120, Issue 8, pp. 2795 - 2804
Journal Article
Journal Article
Journal Article
Nature Neuroscience, ISSN 1097-6256, 07/2003, Volume 6, Issue 7, pp. 701 - 707
Dorsoventral patterning of the telencephalon is established early in forebrain development and underlies many of the regional subdivisions that are critical to... 
MAMMALIAN TELENCEPHALON | FATE MAP | FOREBRAIN | FLOOR PLATE | SONIC HEDGEHOG | BONE MORPHOGENETIC PROTEINS | GENE-EXPRESSION | CHICK-EMBRYO | CENTRAL-NERVOUS-SYSTEM | DIFFERENTIATION | NEUROSCIENCES | Immunohistochemistry | Bone Morphogenetic Proteins - physiology | Homeodomain Proteins - metabolism | Repressor Proteins | Fibroblast Growth Factors - genetics | Wnt Proteins | Ectoderm - physiology | Stem Cells - metabolism | Aging - genetics | Gene Expression Regulation, Developmental | Cell Differentiation | In Situ Hybridization - methods | Organ Culture Techniques | Basic Helix-Loop-Helix Transcription Factors | Fibroblast Growth Factors - physiology | Frizzled Receptors | Proteins - physiology | Fibroblast Growth Factors - classification | Telencephalon - metabolism | Telencephalon - cytology | Paired Box Transcription Factors | Zebrafish Proteins | Embryonic Induction - physiology | Proto-Oncogene Proteins - genetics | PAX6 Transcription Factor | Signal Transduction - genetics | Telencephalon - embryology | Epithelium | Chick Embryo | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | Ectoderm - cytology | Telencephalon - physiology | Pyrroles - pharmacology | Animals | Proto-Oncogene Proteins - physiology | Signal Transduction - physiology | Mice | Transcription Factors | Receptors, Fibroblast Growth Factor - physiology | Eye Proteins | Aging - metabolism | Telencephalon | Neural transmission | Regulation | Research | Gene expression | Analysis | Index Medicus | Pyrroles/pharmacology | Signal Transduction/genetics/physiology | Bone Morphogenetic Proteins/physiology | Homeodomain Proteins/genetics/metabolism | In Situ Hybridization/methods | Gene Expression Regulation; Developmental | Fibroblast Growth Factors/classification/genetics/physiology | Nerve Tissue Proteins/genetics/metabolism | Aging/genetics/metabolism | Stem Cells/metabolism | Ectoderm/cytology/physiology | Proteins/physiology | Receptors; Fibroblast Growth Factor/physiology | Telencephalon/cytology/embryology/metabolism/physiology | Proto-Oncogene Proteins/genetics/physiology | Embryonic Induction/physiology
Journal Article
Cell, ISSN 0092-8674, 2001, Volume 107, Issue 4, pp. 513 - 523
In humans, low peak bone mass is a significant risk factor for osteoporosis. We report that LRP5, encoding the low-density lipoprotein receptor-related protein... 
MINERAL DENSITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | OSTEOBLAST LINEAGE | MOLECULAR-CLONING | MICE | DIFFERENTIATION | BETA-CATENIN | OSTEOPOROSIS | CELL-DEATH | FAMILY | CELL BIOLOGY | Wnt2 Protein | Humans | Child, Preschool | Male | Bone Density - genetics | Wnt Proteins | Mesoderm - cytology | Wnt-5a Protein | Eye - embryology | Osteoporosis - genetics | Animals, Outbred Strains | Dishevelled Proteins | Bone Morphogenetic Proteins - pharmacology | Child | Organ Culture Techniques | Transforming Growth Factor beta | Signal Transduction | Chromosomes, Human, Pair 11 - genetics | Adaptor Proteins, Signal Transducing | Skull - cytology | Wnt3 Protein | Mice | Receptors, LDL - physiology | COS Cells | Species Specificity | LDL-Receptor Related Proteins | DNA, Complementary - genetics | Recombinant Fusion Proteins - physiology | Cercopithecus aethiops | Culture Media, Conditioned - pharmacology | Recombinant Proteins | Transfection | Receptors, LDL - deficiency | Stromal Cells - drug effects | Adult | Female | Phosphoproteins - physiology | Proteins - physiology | Receptors, LDL - genetics | Bone Morphogenetic Protein 2 | Low Density Lipoprotein Receptor-Related Protein-5 | Mice, Inbred C57BL | Zebrafish Proteins | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Eye Abnormalities - genetics | Genes, Recessive | Syndrome | Proteins - genetics | Animals | Proto-Oncogene Proteins - physiology | Heterozygote | Osteoblasts - metabolism | Stromal Cells - cytology | Wnt4 Protein | Proteins | Cell research | Lipoproteins | Growth | Analysis | Physiological aspects | Bones | LDL receptor-related protein 5 | LRP5 protein | low density lipoprotein receptor-related protein 5 | osteoporosis-pseudoglioma syndrome | Index Medicus | Receptors, LDL | Mesoderm | Osteoblasts | Recombinant Fusion Proteins | Eye | Life Sciences | Osteoporosis | Stromal Cells | Eye Abnormalities | Phosphoproteins | Proto-Oncogene Proteins | Bone Density | Biochemistry, Molecular Biology | Culture Media, Conditioned | Skull | Chromosomes, Human, Pair 11 | Bone Morphogenetic Proteins | DNA, Complementary
Journal Article