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Circulation Research, ISSN 0009-7330, 11/2016, Volume 119, Issue 11, pp. 1183 - 1189
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 08/2016, Volume 23, Issue 8, pp. 752 - 754
Journal Article
Cell Reports, ISSN 2211-1247, 09/2016, Volume 16, Issue 12, pp. 3097 - 3102
The Zika virus (ZIKV) poses a major public health emergency. To aid in the development of antivirals, we present two high-resolution crystal structures of the... 
DOMAIN | METHYLATION | INHIBITION | RECOGNITION | CRYSTAL-STRUCTURE | VALIDATION | RNA CAP | CELL BIOLOGY | Methyltransferases - chemistry | Protein Conformation | Viral Nonstructural Proteins - chemistry | Zika Virus - enzymology | Zika Virus - chemistry
Journal Article
Nature Communications, ISSN 2041-1723, 03/2017, Volume 8, Issue 1, p. 14764
Journal Article
Antiviral Research, ISSN 0166-3542, 09/2017, Volume 145, pp. 33 - 43
Journal Article
Journal Article
Antiviral Research, ISSN 0166-3542, 05/2017, Volume 141, pp. 29 - 37
Journal Article
Antiviral Research, ISSN 0166-3542, 03/2017, Volume 139, Issue C, pp. 49 - 58
Journal Article
Archives of Virology, ISSN 0304-8608, 07/2017, Volume 162, Issue 7, pp. 2091 - 2096
Zika virus is considered a major global threat to human kind. Here, we present a crystal structure of one of its essential enzymes, the methyltransferase, with... 
NS5 | TRANSMISSION | VIROLOGY | RNA | FLAVIVIRUS | CRYSTAL-STRUCTURE | INSIGHT | DISCOVERY | BRAZIL | Methyltransferases - antagonists & inhibitors | Zika Virus - enzymology | Adenosine - analogs & derivatives | Enzyme Inhibitors - chemistry | Models, Molecular | Protein Binding | Adenosine - chemistry | Binding Sites | Structure | Transferases | Crystals | Adenine | Enzymes | GTP | Zika virus | Methyltransferase | Crystal structure
Journal Article