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Cell reports (Cambridge), ISSN 2211-1247, 2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
Antimicrobial agents and chemotherapy, ISSN 1098-6596, 2017, Volume 61, Issue 3
As new pathogenic viruses continue to emerge, it is paramount to have intervention strategies that target a common denominator in these pathogens... 
Envelope protein | Antiviral | Zika virus | Virus entry | Chikungunya virus | Resistant mutant | LYSOSOMAL FUNCTION | envelope protein | MICROBIOLOGY | SEMLIKI-FOREST-VIRUS | chikungunya virus | CHLOROQUINE | FULL-LENGTH CDNA | IN-VITRO | antiviral | virus entry | PHARMACOLOGY & PHARMACY | INFECTION | resistant mutant | MUTATIONS | CELL ENTRY | ANTIVIRALS | Zika Virus - genetics | Chikungunya virus - genetics | Membrane Glycoproteins - metabolism | Epithelial Cells - drug effects | Humans | Yellow fever virus - growth & development | Semliki forest virus - growth & development | Virus Internalization - drug effects | Endosomes - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Lysosomes - metabolism | West Nile virus - genetics | Hydrogen-Ion Concentration - drug effects | Endosomes - drug effects | Viral Envelope Proteins - metabolism | Cell Membrane - drug effects | Hepatocytes - drug effects | Membrane Fusion - drug effects | Lysosomes - drug effects | Cell Line | Virus Replication - drug effects | Antiviral Agents - pharmacology | Cricetinae | Gene Expression | Viral Envelope Proteins - genetics | Zika Virus - growth & development | West Nile virus - growth & development | Zika Virus - drug effects | West Nile virus - drug effects | Chikungunya virus - growth & development | Membrane Glycoproteins - genetics | Chikungunya virus - drug effects | Drug Resistance, Viral - genetics | Pyrroles - pharmacology | Yellow fever virus - drug effects | Animals | Semliki forest virus - genetics | Neutral Red - metabolism | Epithelial Cells - virology | Semliki forest virus - drug effects | Hepatocytes - virology | Cell Membrane - virology | Mutation | Proto-Oncogene Proteins c-bcl-2 - genetics | Yellow fever virus - genetics
Journal Article
Cell reports (Cambridge), ISSN 2211-1247, 2019, Volume 26, Issue 6, pp. 1598 - 1613.e8
...) is a secreted glycoprotein involved in viral replication, immune evasion, and vascular leakage during dengue virus infection... 
yellow fever virus | West Nile virus | disease tropism | dengue virus | vascular leak | Japanese encephalitis virus | Zika virus | Flavivirus | NS1 | endothelial permeability | PATHOGENESIS | NONSTRUCTURAL PROTEIN NS1 | DISRUPTION | WEST-NILE-VIRUS | ENHANCEMENT | INFECTION | GLYCOCALYX | DENGUE VIRUS | ASSOCIATION | PLASMA LEAKAGE | CELL BIOLOGY | Liver - virology | Liver - pathology | Zika Virus - genetics | Yellow fever virus - pathogenicity | Humans | Brain - virology | Cell Membrane Permeability | Male | Dengue - pathology | West Nile virus - metabolism | Lung - virology | Viral Nonstructural Proteins - chemistry | West Nile virus - genetics | Encephalitis Virus, Japanese - metabolism | Dengue Virus - pathogenicity | Yellow fever virus - metabolism | Umbilical Veins - pathology | Endothelial Cells - virology | Glycocalyx - chemistry | Zika Virus - metabolism | Dengue - genetics | Zika Virus - pathogenicity | Cell Line | Gene Expression | Lung - pathology | Viral Nonstructural Proteins - genetics | Dermis - virology | Organ Specificity | West Nile virus - pathogenicity | Encephalitis Virus, Japanese - genetics | Dengue Virus - genetics | Glycocalyx - virology | Animals | Virus Replication | Brain - pathology | Dengue - metabolism | Dermis - pathology | Umbilical Veins - virology | Viral Nonstructural Proteins - metabolism | Mice | Dengue Virus - metabolism | Encephalitis Virus, Japanese - pathogenicity | Primary Cell Culture | Endothelial Cells - pathology | Yellow fever virus - genetics
Journal Article
Nature (London), ISSN 1476-4687, 2016, Volume 535, Issue 7610, pp. 159 - 163
Journal Article
Nature immunology, ISSN 1529-2916, 2016, Volume 17, Issue 9, pp. 1102 - 1108
Zika virus (ZIKV) was discovered in 1947 and was thought to lead to relatively mild disease... 
NEUTRALIZING ANTIBODIES | IMMUNOLOGY | CHIKUNGUNYA VIRUS | OUTBREAK | BRAZIL | BRAIN | Immunodominant Epitopes - immunology | Antibody-Dependent Enhancement | Epitope Mapping | Humans | Child, Preschool | Male | Antibodies, Viral - blood | Microcephaly - epidemiology | Antibodies, Monoclonal - blood | Antibodies, Neutralizing - immunology | South America - epidemiology | Immunodominant Epitopes - metabolism | Guillain-Barre Syndrome - epidemiology | Viral Envelope Proteins - metabolism | Female | Dengue - immunology | Child | Antibodies, Monoclonal - immunology | Zika Virus - physiology | Cells, Cultured | Dengue - epidemiology | Cross Reactions | Zika Virus Infection - epidemiology | Virus Replication | Adolescent | Protein Binding | Zika Virus Infection - immunology | Antibodies, Viral - immunology | Dengue Virus - physiology | Viral Envelope Proteins - immunology | Antibodies, Neutralizing - blood | Medical research | Immune response | Comorbidity | Dengue | Medicine, Experimental | Development and progression | Research | Observations | South America | Populations and Evolution | Viral Envelope Proteins | Zika Virus Infection | Microcephaly | Guillain-Barre Syndrome | Life Sciences | Computer Science | Genetics | Bioinformatics | Antibodies, Neutralizing | Parasitology | Quantitative Methods | Zika Virus | Antibodies, Monoclonal | Antibodies, Viral | Dengue Virus | Virology | Microbiology and Parasitology | Santé publique et épidémiologie | Immunodominant Epitopes | Human genetics
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2018, Volume 175, Issue 7, pp. 1931 - 1945.e18
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 2016, Volume 352, Issue 6283, pp. 345 - 349
Journal Article
Nature (London), ISSN 1476-4687, 2016, Volume 536, Issue 7617, pp. 474 - 478
Zika virus (ZIKV) is a flavivirus that is responsible for the current epidemic in Brazil and the Americas(1,2... 
CHALLENGE | HEALTHY-ADULTS | IMMUNOGENICITY | AMERICA | NEUTRALIZING ANTIBODY | SAFETY | MULTIDISCIPLINARY SCIENCES | INFECTION | MICE | MODEL | Antibody Specificity | Immunoglobulin G - isolation & purification | Vaccines, DNA - genetics | Zika Virus - genetics | Vaccines, Subunit - genetics | Humans | Viral Vaccines - genetics | Vaccines, DNA - immunology | Adoptive Transfer | Microcephaly - virology | CD4-Positive T-Lymphocytes - immunology | Zika Virus Infection - virology | Antibodies, Neutralizing - immunology | Immunoglobulin G - immunology | Gene Deletion | Brazil | Zika Virus Infection - complications | Female | Zika Virus Infection - prevention & control | Zika Virus - immunology | Microcephaly - complications | Vaccines, Inactivated - genetics | Viral Envelope Proteins - genetics | Vaccines, Subunit - chemistry | Vaccines, Subunit - immunology | Zika Virus - chemistry | Vaccines, DNA - chemistry | Vaccines, Inactivated - immunology | Animals | Viral Envelope Proteins - chemistry | Viral Vaccines - chemistry | Zika Virus Infection - immunology | Antibodies, Viral - immunology | Viral Envelope Proteins - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Viral Vaccines - immunology | Vaccines, Inactivated - chemistry | Product development | Viral vaccines | Epidemics | Immunoglobulin G | Analysis | Vaccination | World health | DNA vaccines | Birth defects | T cells | Studies | Encephalitis | Immunization | Fetuses | Zika virus | Vaccines | Microcephaly | Deoxyribonucleic acid--DNA
Journal Article