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Cell Reports, ISSN 2211-1247, 09/2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Index Medicus | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
Cell Reports, ISSN 2211-1247, 02/2017, Volume 18, Issue 9, pp. 2113 - 2123
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 02/2017, Volume 24, Issue 2, pp. 184 - 186
The current Zika virus (ZIKV) epidemic is characterized by severe pathogenicity in both children and adults. Sequence changes in ZIKV since its first isolation... 
Cryoelectron Microscopy | Zika Virus - ultrastructure | Cell Line | Animals | Capsid Proteins - chemistry | Protein Structure, Quaternary | Models, Molecular | Virion - ultrastructure | Glycosylation | Protein Processing, Post-Translational | Aedes | Capsid Proteins - ultrastructure | Proteins | Structure | Observations | Pathogens | Zika virus | Crystal structure | Index Medicus
Journal Article
Journal Article
Science, ISSN 0036-8075, 11/2017, Volume 358, Issue 6363, pp. 663 - 667
The Rift Valley fever virus (RVFV) is transmitted by infected mosquitoes, causing severe disease in humans and livestock across Africa. We determined the x-ray... 
LOW-PH | ORGANIZATION | PEPTIDES | RIFT-VALLEY FEVER | MULTIDISCIPLINARY SCIENCES | DISEASE | ENVELOPE GLYCOPROTEIN | SEMLIKI-FOREST-VIRUS | CRYSTALLOGRAPHY | CONFORMATION | Zika Virus - ultrastructure | Amino Acid Sequence | Mutagenesis, Site-Directed | Viral Fusion Proteins - genetics | Humans | Rift Valley fever virus - ultrastructure | Crystallography, X-Ray | Molecular Dynamics Simulation | Zika Virus - chemistry | Cholesterol - chemistry | Chikungunya virus - chemistry | Animals | Rift Valley fever virus - genetics | Viral Fusion Proteins - chemistry | Glycerophospholipids - chemistry | Chikungunya virus - ultrastructure | Conserved Sequence | Livestock - virology | Cell Membrane - virology | Protein Conformation | Viral Fusion Proteins - ultrastructure | Rift Valley fever virus - chemistry | Physiological aspects | Phospholipids | Rift Valley fever | Viral proteins | Health aspects | Epidemics | Membranes | Lecithin | Insertion | Molecular dynamics | Viruses | Hydrophobicity | Cell fusion | Aquatic insects | Proteins | Endocytosis | Coccidioidomycosis | Fusion protein | Crystal structure | Vector-borne diseases | Membrane fusion | Cell membranes | Cell membranes (biology) | Cholesterol | Fever | Aliphatic compounds | Membrane proteins | Mosquitoes | Mutagenesis | Site-directed mutagenesis | Livestock | Index Medicus | Life Sciences
Journal Article