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Molecules (Basel, Switzerland), ISSN 1420-3049, 03/2018, Volume 23, Issue 3, p. 566
A promising means in the search of new small molecules for the treatment of schistosomiasis (amongst other parasitic ailments) is by targeting the parasitic... 
Epigenetics | Virtual screening | Histone deacetylase (HDAC) inhibitors | Schistosomiasis | Docking | Crystal structure | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Apoptosis - drug effects | Zinc - metabolism | Helminth Proteins - chemistry | Anthelmintics - chemical synthesis | Crystallography, X-Ray | Structure-Activity Relationship | Zinc - chemistry | Schistosoma mansoni - genetics | Pyrrolidines - pharmacology | Histone Deacetylase Inhibitors - chemical synthesis | Protein Interaction Domains and Motifs | Schistosoma mansoni - growth & development | Binding Sites | Helminth Proteins - metabolism | Hydroxamic Acids - pharmacology | Schistosoma mansoni - drug effects | Gene Expression | Histone Deacetylases - genetics | Protein Structure, Secondary | Schistosoma mansoni - enzymology | Histone Deacetylases - chemistry | Histone Deacetylases - metabolism | Helminth Proteins - genetics | Chelating Agents - pharmacology | Animals | Pyrrolidines - chemical synthesis | Anthelmintics - pharmacology | Protein Binding | Histone Deacetylase Inhibitors - pharmacology | Molecular Docking Simulation | Chelating Agents - chemical synthesis | Hydroxamic Acids - chemical synthesis | Helminth Proteins - antagonists & inhibitors | Histone deacetylase | Screening | Chromatin | Inhibitors | Catalysis | In vitro methods and tests | Chelates | Zinc | Index Medicus | Chelating Agents/pharmacology | Helminth Proteins/antagonists & inhibitors | Schistosoma mansoni/enzymology | Pyrrolidines/pharmacology | Life Sciences | Histone Deacetylases/genetics | Anthelmintics/chemical synthesis | Schistosoma mansoni/genetics | Helminth Proteins/genetics | Biomolecules | Histone Deacetylase Inhibitors/chemical synthesis | Chelating Agents/chemical synthesis | Pyrrolidines/chemical synthesis | Schistosoma mansoni/growth & development | Hydroxamic Acids/chemical synthesis | Zinc/chemistry | Biochemistry, Molecular Biology | Apoptosis/drug effects | Helminth Proteins/metabolism | Histone Deacetylases/chemistry | Hydroxamic Acids/pharmacology | Anthelmintics/pharmacology | Schistosoma mansoni/drug effects | Histone Deacetylases/metabolism | Helminth Proteins/chemistry | Histone Deacetylase Inhibitors/pharmacology | Zinc/metabolism | crystal structure | docking | virtual screening | histone deacetylase (HDAC) inhibitors | schistosomiasis | epigenetics
Journal Article
Journal of inorganic biochemistry, ISSN 0162-0134, 12/2015, Volume 153, pp. 49 - 59
Heart tissue becomes zinc-depleted and the capacity to mobilize labile zinc is diminished, indicating zinc dyshomeostasis during ischemia/reperfusion (I/R).... 
Hypoxia | Reoxygenation | Proteolysis | Caspase-3 | Zinc | Apoptosis | Biochemistry & Molecular Biology | Physical Sciences | Chemistry, Inorganic & Nuclear | Chemistry | Life Sciences & Biomedicine | Science & Technology | Receptor, Epidermal Growth Factor - genetics | Caspase Inhibitors - pharmacology | Phosphorylation | Receptor, ErbB-2 - genetics | Protein Multimerization | Caspase 3 - metabolism | Receptor, ErbB-2 - metabolism | RNA, Messenger - metabolism | Cell Hypoxia | Receptor, Epidermal Growth Factor - metabolism | Zinc Compounds - pharmacology | Amino Acid Chloromethyl Ketones - pharmacology | Receptor, ErbB-2 - antagonists & inhibitors | Proteasome Inhibitors - pharmacology | Benzothiazoles - pharmacology | Chlorides - pharmacology | Down-Regulation | RNA, Messenger - genetics | Rats | Tyrphostins - pharmacology | Cardiotonic Agents - pharmacology | Leupeptins - pharmacology | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Thiones - pharmacology | Quinazolines - pharmacology | Organometallic Compounds - pharmacology | Proteins | Membrane lipids | Inositol | RNA | Antifungal agents | Permeability | Antibacterial agents | Phosphotransferases | Tyrosine | Cell death | Index Medicus
Journal Article
Journal Article
Journal of Endodontics, ISSN 0099-2399, 2014, Volume 40, Issue 8, pp. 1194 - 1200
Abstract Introduction The objective of this study was to evaluate the biocompatibility, inflammatory response, and odontoblastic potential of Biodentine... 
Endocrinology & Metabolism | Dentistry | Biodentine | nuclear factor–E2-related factor-2 | dental pulp cells | odontoblastic potential | inflammatory response | Biocompatibility | heme oxygenase-1 | nuclear factor-E2-related factor-2 | Life Sciences & Biomedicine | Dentistry, Oral Surgery & Medicine | Science & Technology | Dinoprostone - analysis | Cytokines - analysis | Humans | Dental Cements - pharmacology | Nitric Oxide - analysis | Nitric Oxide Synthase Type II - analysis | Inflammation Mediators - analysis | Mitogen-Activated Protein Kinases - analysis | Alkaline Phosphatase - analysis | Pulp Capping and Pulpectomy Agents - pharmacology | Calcium Compounds - pharmacology | Silicates - pharmacology | Calcification, Physiologic - drug effects | Dental Pulp - cytology | Dental Pulp - drug effects | Materials Testing | Biocompatible Materials - pharmacology | Zinc Oxide-Eugenol Cement - pharmacology | Cyclooxygenase 2 - analysis | Reactive Oxygen Species - analysis | Oxides - pharmacology | NF-E2-Related Factor 2 - analysis | Heme Oxygenase-1 - analysis | Signal Transduction - drug effects | Cell Differentiation - drug effects | Methylmethacrylates - pharmacology | Odontoblasts - drug effects | Bismuth - pharmacology | Root Canal Filling Materials - pharmacology | Aluminum Compounds - pharmacology | Cell Proliferation - drug effects | Drug Combinations
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 11/2007, Volume 104, Issue 48, pp. 19023 - 19028
Journal Article