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Cell Stem Cell, ISSN 1934-5909, 01/2015, Volume 16, Issue 1, pp. 51 - 66
Mesenchymal stem cells (MSCs) reside in the perivascular niche of many organs, including kidney, lung, liver, and heart, although their roles in these tissues... 
REGULATOR | ORIGIN | SONIC HEDGEHOG | PATHWAY | BONE-MARROW NICHE | MYOFIBROBLASTS | NG2 PROTEOGLYCAN | EXPRESSION | MESENCHYMAL STEM-CELLS | GROWTH FACTOR-AA | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Organ Specificity - drug effects | Diphtheria Toxin - pharmacology | Neovascularization, Physiologic - drug effects | Pericytes - drug effects | Blood Vessels - metabolism | Blood Vessels - pathology | Humans | Fibrosis - metabolism | Cell Lineage - drug effects | Myofibroblasts - metabolism | Mesenchymal Stromal Cells - cytology | Mesenchymal Stromal Cells - ultrastructure | Kruppel-Like Transcription Factors - metabolism | Pericytes - pathology | Bone Marrow Cells - drug effects | Colony-Forming Units Assay | Aorta - physiopathology | Homeostasis - drug effects | Heart Ventricles - pathology | Receptor, Platelet-Derived Growth Factor beta - metabolism | Mesenchymal Stromal Cells - drug effects | Endothelial Cells - metabolism | Aorta - drug effects | Pericytes - metabolism | Cells, Cultured | Proteoglycans - metabolism | Antigens - metabolism | Aorta - pathology | Myofibroblasts - cytology | Animals | Heart Ventricles - physiopathology | Cell Differentiation - drug effects | Endothelial Cells - cytology | Blood Vessels - drug effects | Mice | Stem Cell Niche - drug effects | Zinc Finger Protein GLI1 | Fibrosis - pathology | Bone Marrow Cells - metabolism | Endothelial Cells - drug effects | Heart Ventricles - drug effects | Index Medicus
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 03/2017, Volume 28, Issue 3, pp. 776 - 784
Journal Article
Cell Stem Cell, ISSN 1934-5909, 06/2017, Volume 20, Issue 6, pp. 785 - 800.e8
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2015, Volume 34, Issue 2, pp. 200 - 217
Hedgehog signaling is essential for tissue development and stemness, and its deregulation has been observed in many tumors. Aberrant activation of Hedgehog... 
interaction | Hedgehog | cancer | li1 | DNA | li inhibitors | Gli inhibitors | Gli1-DNA interaction | Cancer | CANCER-CELLS | STEM-CELLS | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | HUMAN GLIOMA | CELL BIOLOGY | PATHWAY BLOCKADE | INHIBITION | GROWTH | SCORING FUNCTIONS | MEDULLOBLASTOMA | Embryo, Mammalian - drug effects | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Receptors, G-Protein-Coupled - metabolism | Isoflavones - pharmacology | Cerebellum - drug effects | Embryo, Mammalian - metabolism | Kruppel-Like Transcription Factors - metabolism | Smoothened Receptor | Female | Glioblastoma - metabolism | Receptors, Cell Surface - physiology | Patched Receptors | DNA - drug effects | Fibroblasts - metabolism | Mutagenesis, Site-Directed | Cerebellum - metabolism | DNA - metabolism | Mice, SCID | Mutation - genetics | Kruppel-Like Transcription Factors - chemistry | Molecular Dynamics Simulation | Mice, Knockout | Animals | Embryonic Stem Cells - drug effects | Signal Transduction - drug effects | Embryo, Mammalian - cytology | Fibroblasts - drug effects | Glioblastoma - pathology | Cerebellum - cytology | Mice, Inbred NOD | Fibroblasts - cytology | Mice | Mice, Inbred BALB C | Zinc Finger Protein GLI1 | Glioblastoma - drug therapy | Kruppel-Like Transcription Factors - genetics | Medical research | Amino acids | Molecular biology | Deoxyribonucleic acid--DNA | Stem cells | Tumors | Index Medicus | Gli1–DNA interaction
Journal Article
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7573, pp. 448 - 452
Journal Article
EMBO reports, ISSN 1469-221X, 08/2017, Volume 18, Issue 8, pp. 1318 - 1330
Journal Article
Development (Cambridge), ISSN 0950-1991, 04/2017, Volume 144, Issue 7, pp. 1159 - 1164
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7507, pp. 90 - 93
Journal Article
Oncogene, ISSN 0950-9232, 03/2017, Volume 36, Issue 13, pp. 1849 - 1861
BRAF inhibitor (BRAFi) therapy for melanoma patients harboring the V600E mutation is initially highly effective, but almost all patients relapse within a few... 
TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACQUIRED-RESISTANCE | DRUG-RESISTANCE | MESENCHYMAL TRANSITION | MEK INHIBITORS | CELL BIOLOGY | METASTATIC MELANOMA | GROWTH-FACTOR-BETA | IN-VITRO | ONCOLOGY | GENETICS & HEREDITY | BRAF INHIBITOR RESISTANCE | UP-REGULATION | Zinc Finger Protein GLI1 - metabolism | Humans | Zinc Finger Protein Gli2 | Hedgehog Proteins - metabolism | Drug Resistance, Neoplasm | Gene Knockdown Techniques | Kruppel-Like Transcription Factors - metabolism | Melanoma - genetics | Zinc Finger Protein GLI1 - antagonists & inhibitors | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Melanoma - metabolism | Cell Survival - drug effects | Cellular Senescence - genetics | Gene Expression | Zinc Finger Protein GLI1 - genetics | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Signal Transduction - drug effects | Protein Kinase Inhibitors - therapeutic use | Melanoma - drug therapy | Cell Line, Tumor | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Kruppel-Like Transcription Factors - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | Care and treatment | Melanoma | Genetic aspects | Research | Transforming growth factors | Health aspects | Cancer | Signal transduction | Oncology | Transcription factors | Mutation | Index Medicus | Original
Journal Article