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1. Full Text GLI3 repressor but not GLI3 activator is essential for mouse eye patterning and morphogenesis
by Wiegering, Antonia and Petzsch, Patrick and Köhrer, Karl and Rüther, Ulrich and Gerhardt, Christoph
Developmental biology, ISSN 0012-1606, 06/2019, Volume 450, Issue 2, pp. 141 - 154
Hedgehog | DKK | Retina | Lens | β-CATENIN | Eye development | WNT | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Zinc Finger Protein Gli3 - metabolism | Mice, Transgenic | Retina - embryology | Nerve Tissue Proteins - genetics | Zinc Finger Protein Gli3 - genetics | Organogenesis | Nerve Tissue Proteins - metabolism | Animals | Protein Isoforms - metabolism | Embryo, Mammalian - embryology | Retina - cytology | Embryo, Mammalian - cytology | Mice | Wnt Signaling Pathway | Protein Isoforms - genetics | Molecular biology | Index Medicus
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2. Full Text MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression
by Hyun, Jeongeun and Wang, Sihyung and Kim, Jieun and Rao, Kummara Madhusudana and Park, Soo Yong and Chung, Ildoo and Ha, Chang-Sik and Kim, Sang-Woo and Yun, Yang H and Jung, Youngmi
Nature communications, ISSN 2041-1723, 03/2016, Volume 7, Issue 1, pp. 10993 - 10993
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein Binding - genetics | Nanoparticles - chemistry | Receptors, G-Protein-Coupled - metabolism | Carbon Tetrachloride | Humans | Zinc Finger Protein Gli2 | Zinc Finger Protein Gli3 | Hepatic Stellate Cells - metabolism | Molecular Sequence Data | Male | MicroRNAs - metabolism | RNA, Messenger - metabolism | Kruppel-Like Transcription Factors - metabolism | Base Sequence | Carcinoma, Hepatocellular - genetics | Smoothened Receptor | Liver Cirrhosis - genetics | Down-Regulation | Mice, Inbred C57BL | RNA, Messenger - genetics | Gene Expression Regulation | Methionine | Nerve Tissue Proteins - genetics | Ethionine | Nerve Tissue Proteins - metabolism | Animals | Transcription Factor RelA - metabolism | Choline | Liver Cirrhosis - pathology | MicroRNAs - genetics | Chronic Disease | Kruppel-Like Transcription Factors - genetics | Index Medicus
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3. Full Text New insights into genotype-phenotype correlation for GLI3 mutations
by Démurger, Florence and Ichkou, Amale and Mougou-Zerelli, Soumaya and Le Merrer, Martine and Goudefroye, Géraldine and Delezoide, Anne-Lise and Quélin, Chloé and Manouvrier, Sylvie and Baujat, Geneviève and Fradin, Mélanie and Pasquier, Laurent and Megarbané, André and Faivre, Laurence and Baumann, Clarisse and Nampoothiri, Sheela and Roume, Joëlle and Isidor, Bertrand and Lacombe, Didier and Delrue, Marie-Ange and Mercier, Sandra and Philip, Nicole and Schaefer, Elise and Holder, Muriel and Krause, Amanda and Laffargue, Fanny and Sinico, Martine and Amram, Daniel and André, Gwenaelle and Liquier, Alain and Rossi, Massimiliano and Amiel, Jeanne and Giuliano, Fabienne and Boute, Odile and Dieux-Coeslier, Anne and Jacquemont, Marie-Line and Afenjar, Alexandra and Van Maldergem, Lionel and Lackmy-Port-Lis, Marylin and Vincent- Delorme, Catherine and Chauvet, Marie-Liesse and Cormier-Daire, Valérie and Devisme, Louise and Geneviève, David and Munnich, Arnold and Viot, Géraldine and Raoul, Odile and Romana, Serge and Gonzales, Marie and Encha-Razavi, Ferechte and Odent, Sylvie and Vekemans, Michel and Attie-Bitach, Tania
European journal of human genetics : EJHG, ISSN 1018-4813, 01/2015, Volume 23, Issue 1, pp. 92 - 102
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Gene Expression | Genetic Association Studies | Humans | Zinc Finger Protein Gli3 | In Situ Hybridization, Fluorescence | Acrocephalosyndactylia - genetics | Nerve Tissue Proteins - genetics | Haploinsufficiency | Phenotype | DNA Mutational Analysis | Abnormalities, Multiple - diagnosis | Gene Rearrangement | Acrocephalosyndactylia - diagnosis | Family | Mutation | Kruppel-Like Transcription Factors - genetics | Abnormalities, Multiple - genetics | Cohort Studies | Epiglottis | Phenotypes | Greig cephalopolysyndactyly syndrome | Fetuses | Lethality | Hypothalamus | Gene expression | Gene deletion | Gli3 protein | Corpus callosum | Proteins | Clonal deletion | Polydactyly | Genetics | Neoplasia | Genotypes | Index Medicus | Life Sciences
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4. Full Text Kinetics of Hedgehog-Dependent Full-Length Gli3 Accumulation in Primary Cilia and Subsequent Degradation
by Xiaohui Wen and Cary K. Lai and Marie Evangelista and Jo-Anne Hongo and Frederic J. de Sauvage and Suzie J. Scales
Molecular and Cellular Biology, ISSN 0270-7306, 04/2010, Volume 30, Issue 8, pp. 1910 - 1922
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Receptors, G-Protein-Coupled - metabolism | Humans | Zinc Finger Protein Gli2 | Zinc Finger Protein Gli3 | Hedgehog Proteins - metabolism | Hedgehog Proteins - genetics | Kruppel-Like Transcription Factors - metabolism | Smoothened Receptor | Cilia - ultrastructure | Patched Receptors | Cyclic AMP-Dependent Protein Kinases - metabolism | Cell Line | Receptors, Cell Surface - metabolism | Nerve Tissue Proteins - genetics | Cilia - metabolism | Nerve Tissue Proteins - metabolism | Animals | Signal Transduction - physiology | Mice | Mice, Inbred BALB C | Receptors, G-Protein-Coupled - genetics | Proteasome Endopeptidase Complex - metabolism | Kruppel-Like Transcription Factors - genetics | RNA, Small Interfering - metabolism | Receptors, Cell Surface - genetics | Index Medicus
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5. Full Text The ciliary EVC/EVC2 complex interacts with smo and controls hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia
by Caparrós-Martín, Jose A and Valencia, María and Reytor, Edel and Pacheco, María and Fernandez, Margarita and Perez-Aytes, Antonio and Gean, Esther and Lapunzina, Pablo and Peters, Heiko and Goodship, Judith A and Ruiz-Perez, Victor L
Human molecular genetics, ISSN 0964-6906, 01/2013, Volume 22, Issue 1, pp. 124 - 139
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Receptors, G-Protein-Coupled - metabolism | Zinc Finger Protein Gli3 | Hedgehog Proteins - metabolism | Cilia - metabolism | Protein Transport | Nerve Tissue Proteins - metabolism | Animals | Kruppel-Like Transcription Factors - metabolism | Membrane Proteins - physiology | Mice, Mutant Strains | Smoothened Receptor | Membrane Proteins - metabolism | Mice | Chondrocytes - metabolism | Repressor Proteins - metabolism | Index Medicus
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6. Full Text Inhibitory Gli3 Activity Negatively Regulates Wnt/β-Catenin Signaling
by Ulloa, Fausto and Itasaki, Nobue and Briscoe, James
Current biology, ISSN 0960-9822, 03/2007, Volume 17, Issue 6, pp. 545 - 550
DEVBIO | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Xenopus | Signal Transduction | Humans | Embryo, Nonmammalian - metabolism | Gene Expression Regulation | Zinc Finger Protein Gli3 | Hedgehog Proteins - metabolism | Embryonic Development | Wnt Proteins - metabolism | Chick Embryo | Nerve Tissue Proteins - genetics | beta Catenin - metabolism | Embryo, Mammalian - metabolism | Protein Interaction Mapping | Nerve Tissue Proteins - metabolism | Animals | Wnt Proteins - genetics | Hedgehog Proteins - genetics | Kruppel-Like Transcription Factors - metabolism | beta Catenin - antagonists & inhibitors | Wnt3 Protein | Mice | Wnt Proteins - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | Index Medicus
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7. Full Text A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation
by Adhikari, Kaustubh and Fuentes-Guajardo, Macarena and Quinto-Sánchez, Mirsha and Mendoza-Revilla, Javier and Camilo Chacón-Duque, Juan and Acuña-Alonzo, Victor and Jaramillo, Claudia and Arias, William and Lozano, Rodrigo Barquera and Pérez, Gastón Macín and Gómez-Valdés, Jorge and Villamil-Ramírez, Hugo and Hunemeier, Tábita and Ramallo, Virginia and Silva De Cerqueira, Caio C and Hurtado, Malena and Villegas, Valeria and Granja, Vanessa and Gallo, Carla and Poletti, Giovanni and Schuler-Faccini, Lavinia and Salzano, Francisco M and Bortolini, Maria-Cátira and Canizales-Quinteros, Samuel and Cheeseman, Michael and Rosique, Javier and Bedoya, Gabriel and Rothhammer, Francisco and Headon, Denis and González-José, Rolando and Balding, David and Ruiz-Linares, Andrés
Nature communications, ISSN 2041-1723, 05/2016, Volume 7, Issue 1, pp. 11616 - 11616
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Paired Box Transcription Factors - genetics | Genome-Wide Association Study | Humans | Edar Receptor - genetics | Nerve Tissue Proteins - genetics | Zinc Finger Protein Gli3 - genetics | Latin America | Young Adult | Anatomic Variation | Animals | Face - anatomy & histology | Cadherin Related Proteins - genetics | Adult | Mice | Polymorphism, Single Nucleotide | Core Binding Factor Alpha 1 Subunit - genetics | Maxillofacial Development - genetics | Index Medicus
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8. Full Text Direct Interactions Between Gli3, Wnt8b, and Fgfs Underlie Patterning of the Dorsal Telencephalon
by Hasenpusch-Theil, Kerstin and Watson, Julia A and Theil, Thomas
Cerebral cortex (New York, N.Y. 1991), ISSN 1047-3211, 02/2017, Volume 27, Issue 2, pp. 1137 - 1148
Fgf17 | Wnt8b | Fgf15 | patterning | Gli3 | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Fibroblast Growth Factors - genetics | Wnt Signaling Pathway - physiology | Male | Prosencephalon - physiology | Wnt Proteins - genetics | Gene Expression Regulation, Developmental | Thalamus - physiology | Female | Prosencephalon - metabolism | Fibroblast Growth Factors - physiology | Nerve Tissue Proteins - physiology | Telencephalon - metabolism | Mice, Inbred C57BL | Mice, Transgenic | Signal Transduction - genetics | Telencephalon - embryology | Nerve Tissue Proteins - genetics | Zinc Finger Protein Gli3 - genetics | Mice, Inbred C3H | Pregnancy | Zinc Finger Protein Gli3 - physiology | Telencephalon - physiology | Thalamus - embryology | Animals | Wnt Signaling Pathway - genetics | Signal Transduction - physiology | Mice | Wnt Proteins - physiology | Index Medicus
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