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1. Zinc finger proteins
: from atomic contact to cellular function
by Iuchi, Shiro and Kuldell, Natalie
2005, Molecular biology intelligence unit, ISBN 9780306482298, 276
"Zinc Finger Proteins" is the first book to systematically assemble knowledge of various zinc finger proteins belonging to several families and to describe... 
Zinc-finger proteins | Biology, life sciences | Zinc proteins | Life Sciences | Biochemistry, general | Cancer Research | Cell Biology
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2. Full Text Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)
by Thibodeau-Beganny, Stacey and Peterson, Randall T and Joung, J Keith and Pierick, Christopher J and Cifuentes, Daniel and Zhang, Feng and Voytas, Daniel F and Dahlborg, Elizabeth J and Sander, Jeffry D and Cade, Lindsay and Goodwin, Mathew J and Curtin, Shaun J and Langenau, David M and Stupar, Robert M and Hoffman, Ellen and Khayter, Cyd and Blackburn, Jessica S and Giraldez, Antonio J and Qi, Yiping and Yeh, Jing-Ruey J and Maeder, Morgan L and Reyon, Deepak and Dobbs, Drena
Nature Methods, ISSN 1548-7091, 01/2011, Volume 8, Issue 1, pp. 67 - 69
Engineered zinc-finger nucleases (ZFNs) enable targeted genome modification. Here we describe context-dependent assembly (CoDA), a platform for engineering... 
TARGETED MUTAGENESIS | DNA RECOGNITION | BIOCHEMICAL RESEARCH METHODS | Arabidopsis - genetics | DNA-Binding Proteins - metabolism | Endonucleases - genetics | Animals | Protein Engineering | Zinc Fingers - genetics | Zinc Fingers - physiology | Endonucleases - metabolism | DNA-Binding Proteins - genetics | Genome | Soybeans - genetics | Zebrafish - genetics | Arabidopsis thaliana | Usage | Physiological aspects | DNA synthesis | Genetic aspects | Genetic engineering | Research | Zinc finger proteins | Genomics | Research methodology | Cloning | Zinc
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3. Full Text Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
by Amora, Ranier and Miller, Jeffrey C and Mitalipova, Maisam and Katibah, George E and Rebar, Edward J and Urnov, Fyodor D and Jaenisch, Rudolf and Gregory, Philip D and Boydston, Elizabeth A and Beard, Caroline and Hockemeyer, Dirk and Zeitler, Bryan and Meng, Xiangdong and Soldner, Frank and Gao, Qing and Zhang, Lei and DeKelver, Russell C
Nature Biotechnology, ISSN 1087-0156, 09/2009, Volume 27, Issue 9, pp. 851 - 857
Realizing the full potential of human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) requires efficient methods for genetic... 
SOMATIC-CELLS | ELECTROPORATION | INTEGRATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EMBRYONIC STEM-CELLS | DISEASE | PLURIPOTENCY | IDENTIFICATION | LOCUS | Immunohistochemistry | Cell Line | Gene Targeting - methods | Green Fluorescent Proteins - metabolism | Gene Expression | Homeodomain Proteins - metabolism | Humans | Pluripotent Stem Cells - physiology | Gene Silencing | Green Fluorescent Proteins - genetics | Transcription Factors - genetics | Recombinant Fusion Proteins - metabolism | Deoxyribonucleases - metabolism | Embryonic Stem Cells - physiology | Homeodomain Proteins - genetics | Octamer Transcription Factor-3 - genetics | Transcription Factors - metabolism | Deoxyribonucleases - genetics | Octamer Transcription Factor-3 - metabolism | Recombinant Fusion Proteins - genetics | Zinc Fingers - physiology | Nucleases | Usage | Gene targeting | Physiological aspects | Genetic aspects | Research | Zinc finger proteins | Embryonic stem cells | Biotechnology | Genetic engineering | Gene expression | Zinc | Stem cells
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4. Full Text Genome engineering with zinc-finger nucleases
by Carroll, Dana
Genetics, ISSN 0016-6731, 08/2011, Volume 188, Issue 4, pp. 773 - 782
Zinc-finger nucleases (ZFNs) are targetable DNA cleavage reagents that have been adopted as gene-targeting tools. ZFN-induced double-strand breaks are subject... 
CLEAVAGE DOMAIN | STEM-CELLS | HUMAN-CELLS | GENETICS & HEREDITY | TARGETED GENE DISRUPTION | DOUBLE-STRAND BREAKS | HOMOLOGOUS RECOMBINATION | SACCHAROMYCES-CEREVISIAE | KNOCKOUT RATS | RESTRICTION-ENDONUCLEASE | DNA-BINDING SPECIFICITY | Gene Targeting | Animals | Genetic Engineering | Humans | Genome - genetics | Substrate Specificity | Zinc Fingers - physiology | Endonucleases - metabolism | DNA Breaks, Double-Stranded | Genetic engineering | Zinc finger proteins | Research | Mutagenesis | DNA repair | Proteins | Genotype & phenotype | Efficiency | Technological change | Genomes | Mutation | Gene expression | Deoxyribonucleic acid--DNA | Review
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5. Full Text Sticky fingers: zinc-fingers as protein-recognition motifs
by Gamsjaeger, Roland and Liew, Chu Kong and Loughlin, Fionna E and Crossley, Merlin and Mackay, Joel P
Trends in Biochemical Sciences, ISSN 0968-0004, 2007, Volume 32, Issue 2, pp. 63 - 70
Zinc-fingers (ZnFs) are extremely abundant in higher eukaryotes. Once considered to function exclusively as sequence-specific DNA-binding motifs, ZnFs are now... 
REPRESSOR COMPLEX | TRANSCRIPTION FACTOR GATA-1 | UBIQUITIN LIGASE COMPLEX | CREB-BINDING PROTEIN | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | STRUCTURAL BASIS | REVEALS 2 MODES | DNA RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHD FINGER | COILED-COIL | DNA-Binding Proteins - metabolism | Protein Structure, Tertiary | Animals | Humans | Models, Molecular | Protein Binding | Ligands | Zinc Fingers - physiology | Amino Acid Motifs | Eukaryotes | Zinc finger proteins | Research | DNA binding proteins | Protein binding | Proteins
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6. Full Text KRAB zinc finger proteins
by Ecco, Gabriela and Imbeault, Michael and Trono, Didier
Development (Cambridge), ISSN 0950-1991, 08/2017, Volume 144, Issue 15, pp. 2719 - 2729
Kruppel-associated box domain zinc finger proteins (KRAB-ZFPs) are the largest family of transcriptional regulators in higher vertebrates. Characterized by an... 
Co-option | Endovirome | Transposable element | Gene regulation | KRAB-ZFP | Speciation | DNA METHYLATION | PROMOTER METHYLATION | TRANSCRIPTION | TRANSPOSABLE ELEMENTS | DEVELOPMENTAL BIOLOGY | HUMAN PREIMPLANTATION EMBRYOS | ENDOGENOUS RETROVIRUSES | EVOLUTION | EMBRYONIC STEM-CELLS | GENE-EXPRESSION | BINDING | Repressor Proteins - chemistry | Transcription Factors - chemistry | Humans | Gene Expression Regulation | Repressor Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Cell Differentiation - genetics | Animals | Models, Biological | DNA Transposable Elements - genetics | Zinc Fingers - genetics | Zinc Fingers - physiology | Cell Differentiation - physiology | Repressor Proteins - metabolism | Evolution | Zinc finger proteins | Transcription | Zinc finger | Deoxyribonucleic acid--DNA | Kruppel protein
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7. Full Text Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures
by Miller, Jeffrey C and Vo, Thuy D and Xia, Danny F and Doyon, Yannick and Gregory, Philip D and Holmes, Michael C and Urnov, Fyodor D and Greenberg, Shon G and Mendel, Matthew C and Wang, Jianbin
Nature Methods, ISSN 1548-7091, 01/2011, Volume 8, Issue 1, pp. 74 - 79
Zinc-finger nucleases (ZFNs) drive efficient genome editing by introducing a double-strand break into the targeted gene. Cleavage is induced when two... 
CELLS | DOMAIN | DNA CLEAVAGE | FOKI | BIOCHEMICAL RESEARCH METHODS | GENE DISRUPTION | DIMERIZATION | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Endonucleases - genetics | Saccharomyces cerevisiae - genetics | Saccharomyces cerevisiae - enzymology | Zinc Fingers - genetics | Zinc Fingers - physiology | DNA - metabolism | Endonucleases - metabolism | DNA-Binding Proteins - genetics | Genome | Dimerization | Nucleases | Usage | Physiological aspects | Genetic engineering | Research | Zinc finger proteins | Structure | Molecular structure | Genomics | Research methodology | Zinc | Binding sites
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8. Full Text A20 inhibits LUBAC‐mediated NF‐κB activation by binding linear polyubiquitin chains via its zinc finger 7
by Verhelst, Kelly and Carpentier, Isabelle and Kreike, Marja and Meloni, Laura and Verstrepen, Lynn and Kensche, Tobias and Dikic, Ivan and Beyaert, Rudi
The EMBO Journal, ISSN 0261-4189, 10/2012, Volume 31, Issue 19, pp. 3845 - 3855
Linear polyubiquitination of proteins has recently been implicated in NF‐κB signalling and is mediated by the linear ubiquitin chain assembly complex (LUBAC),... 
TNFAIP3 | NF‐κB | zinc finger | ubiquitin | A20 | NF-kB | CELLS | DOMAIN | PROTEIN | UBIQUITIN-BINDING | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ASSEMBLY COMPLEX | TNF | DEFICIENCY | CELL BIOLOGY | NF-kappa B | INFLAMMATION | NEMO | Polyubiquitin - metabolism | Humans | NF-kappa B - metabolism | Nuclear Proteins - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | DNA-Binding Proteins - metabolism | Tumor Necrosis Factor-alpha - pharmacology | I-kappa B Kinase - metabolism | Signal Transduction - drug effects | HEK293 Cells | Signal Transduction - physiology | Tumor Necrosis Factor alpha-Induced Protein 3 | Zinc Fingers - physiology | Protein Binding - physiology | NF-κB
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9. Full Text A Zinc Finger Transcription Factor ART1 Regulates Multiple Genes Implicated in Aluminum Tolerance in Rice
by Naoki Yamaji and Chao Feng Huang and Sakiko Nagao and Masahiro Yano and Yutaka Sato and Yoshiaki Nagamura and Jian Feng Ma
The Plant Cell, ISSN 1040-4651, 10/2009, Volume 21, Issue 10, pp. 3339 - 3349
Aluminum (Al) toxicity is the major limiting factor of crop production on acid soils, but some plant species have evolved ways of detoxifying Al. Here, we... 
Yeasts | Aluminum | Cell walls | Genes | Root growth | Gene expression regulation | Plants | Acid soils | Rice | Plant cells | ABC TRANSPORTER | AL TOLERANCE | QUANTITATIVE-TRAIT LOCI | MALATE TRANSPORTERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ROOT-GROWTH | ACID SOILS | PLANT SCIENCES | CELL BIOLOGY | ORYZA-SATIVA L | ACTIVATED CITRATE | RESISTANCE | ARABIDOPSIS | Immunohistochemistry | Transcription Factors - physiology | Oligonucleotide Array Sequence Analysis | Oryza - metabolism | Plant Proteins - physiology | Gene Expression Regulation, Plant - genetics | Molecular Sequence Data | Aluminum - toxicity | Oryza - drug effects | Transcription Factors - genetics | Plant Proteins - genetics | Two-Hybrid System Techniques | Gene Expression Regulation, Plant - drug effects | Oryza - genetics | Zinc Fingers - genetics | Zinc Fingers - physiology | Transcription factors | Plant defenses | Physiological aspects | Genetic aspects | Research | Index Medicus
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10. Full Text A previously unknown zinc finger protein, DST, regulates drought and salt tolerance in rice via stomatal aperture control
by Huang, Xin-Yuan and Chao, Dai-Yin and Gao, Ji-Ping and Zhu, Mei-Zhen and Shi, Min and Lin, Hong-Xuan
Genes and Development, ISSN 0890-9369, 08/2009, Volume 23, Issue 15, pp. 1805 - 1817
Abiotic stresses, such as drought and salinity, lead to crop growth damage and a decrease in crop yields. Stomata control CO2 uptake and optimize water use... 
Salt tolerance | Zinc finger protein | Hydrogen peroxide | Drought tolerance | Stomatal aperture | Rice | stomatal aperture | ARABIDOPSIS-THALIANA | OXIDATIVE STRESS | hydrogen peroxide | GLUTATHIONE S-TRANSFERASES | DEVELOPMENTAL BIOLOGY | CELL BIOLOGY | SIGNAL-TRANSDUCTION | STRESS RESPONSES | zinc finger protein | GENETICS & HEREDITY | salt tolerance | GENE-EXPRESSION | drought tolerance | HYDROGEN-PEROXIDE | GUARD-CELLS | ABSCISIC-ACID | TRANSCRIPTION FACTOR | Amino Acid Sequence | Hydrogen Peroxide | Molecular Sequence Data | Oryza - physiology | Gene Expression Profiling | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Plant Proteins - genetics | Sequence Alignment | Oryza - genetics | Droughts | Plant Proteins - chemistry | Gene Expression Regulation, Plant | Salt-Tolerance - genetics | Salt-Tolerance - physiology | Zinc Fingers - genetics | Plant Proteins - metabolism | Zinc Fingers - physiology | Mutation | Plant Stomata - physiology | Halophytes | Analysis | Environmental aspects | Genetic aspects | Genetic engineering | Zinc finger proteins | Chemical properties | Research Paper
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11. Full Text Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF‐κB regulation
by Tokunaga, Fuminori and Nishimasu, Hiroshi and Ishitani, Ryuichiro and Goto, Eiji and Noguchi, Takuya and Mio, Kazuhiro and Kamei, Kiyoko and Ma, Averil and Iwai, Kazuhiro and Nureki, Osamu
The EMBO Journal, ISSN 0261-4189, 10/2012, Volume 31, Issue 19, pp. 3856 - 3870
LUBAC (linear ubiquitin chain assembly complex) activates the canonical NF‐κB pathway through linear polyubiquitination of NEMO (NF‐κB essential modulator,... 
NF‐κB | deubiquitinase | ubiquitin | lymphoma | A20 | NF-κB | ACTIVATION | UBIQUITIN LIGASE | NZF DOMAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHAIN ASSEMBLY COMPLEX | CELL BIOLOGY | NF-kappa B | STRUCTURAL BASIS | CELL LYMPHOMA | PROTEIN A20 | BINDING | NEMO | INNATE IMMUNITY | Protein Binding - genetics | Deubiquitinating Enzyme CYLD | Polyubiquitin - biosynthesis | Humans | Ubiquitin - metabolism | Crystallography, X-Ray | NF-kappa B - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Lymphoma, B-Cell - genetics | DNA-Binding Proteins - metabolism | I-kappa B Kinase - metabolism | HEK293 Cells | Tumor Necrosis Factor alpha-Induced Protein 3 | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Receptors, Tumor Necrosis Factor - metabolism | Receptors, Tumor Necrosis Factor - chemistry | Tumor Suppressor Proteins - metabolism | Ubiquitin - chemistry | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Signal Transduction - drug effects | Intracellular Signaling Peptides and Proteins - chemistry | Protein Conformation | Signal Transduction - physiology | Zinc Fingers - physiology | Mutation
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12. Full Text Targeted gene knockout by direct delivery of zinc-finger nuclease proteins
by Gaj, Thomas and Guo, Jing and Kato, Yoshio and Sirk, Shannon J and Barbas, Carlos F
Nature Methods, ISSN 1548-7091, 08/2012, Volume 9, Issue 8, pp. 805 - 807
Zinc-finger nucleases (ZFNs) are versatile reagents that have redefined genome engineering. Realizing the full potential of this technology requires the... 
CELLS | DISRUPTION | BIOCHEMICAL RESEARCH METHODS | Genetic Engineering - methods | Amino Acid Sequence | Catalytic Domain | Cricetinae | Peptides - chemistry | Humans | Cell Membrane Permeability | Molecular Sequence Data | Receptors, CCR5 - genetics | Recombinant Fusion Proteins - chemistry | Recombinant Fusion Proteins - metabolism | Gene Knockout Techniques - methods | Amino Acid Motifs | tat Gene Products, Human Immunodeficiency Virus - chemistry | Deoxyribonucleases, Type II Site-Specific - metabolism | Animals | Deoxyribonucleases, Type II Site-Specific - chemistry | Recombinant Fusion Proteins - genetics | Zinc Fingers - genetics | Zinc Fingers - physiology | CHO Cells | Physiological aspects | Nucleases | Genetic aspects | Research | Zinc finger proteins | Genes | Proteins | Genetic engineering | Gene therapy | Genomics | Cells
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