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udp-3-o--n-acetylglucosamine deacetylase (4) 4
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amino acids (3) 3
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zinc-dependent enzyme (3) 3
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acid phosphatase - metabolism (2) 2
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anti-bacterial agents - chemistry (2) 2
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Chemistry & Biology, ISSN 1074-5521, 2008, Volume 15, Issue 6, pp. 533 - 545
Journal Article
Biotechnology and Bioengineering, ISSN 0006-3592, 05/2016, Volume 113, Issue 5, pp. 1024 - 1034
Journal Article
by Zhou, P and Zhao, JS
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, ISSN 1388-1981, 11/2017, Volume 1862, Issue 11, pp. 1424 - 1438
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 05/2017, Volume 18, Issue 5, p. 761
As an important target for the development of novel antibiotics, UDP-3-O-(R-3-hydroxymyristoyl)- N-acetylglucosamine deacetylase (LpxC) has been widely... 
Inhibitory mechanism | Drug-resistance | Methylsulfone hydroxamate | 3D-QSAR | LpxC | Molecular dynamics simulation | Free energy landscape | DESIGN | COMPLEX | ZINC-DEPENDENT DEACETYLASE | MECHANISM | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | molecular dynamics simulation | ESCHERICHIA-COLI | methylsulfone hydroxamate | CHEMISTRY, MULTIDISCIPLINARY | free energy landscape | CONTINUUM MODELS | BIOLOGICAL EVALUATION | drug-resistance | FORCE-FIELD | inhibitory mechanism | ENDOTOXIN BIOSYNTHESIS | Catalytic Domain | Enzyme Inhibitors - pharmacology | Water - metabolism | Hydroxamic Acids - chemistry | Amidohydrolases - antagonists & inhibitors | Amidohydrolases - chemistry | Molecular Dynamics Simulation | Hydrogen Bonding | Pseudomonas aeruginosa - enzymology | Enzyme Inhibitors - chemistry | Protein Binding | Molecular Docking Simulation | Hydroxamic Acids - pharmacology | Quantitative Structure-Activity Relationship | Residues | Molecular structure | N-Acetylglucosamine | Molecular dynamics | Catalytic activity | Structure-activity relationships | Design analysis | Pseudomonas | Hydrogen bonding | Dynamical systems | Molecular docking | Design engineering | Hydrogen bonds | Clusters | Chemical bonds | Mathematical models | Catalysis | Computer simulation | Hydrolase | Electrostatic properties | Free energy | Zinc | Molecular modelling | Inhibitors | Antibiotics | Simulation | N-Acetylglucosamine deacetylase | Binding energy | Molecular biology | Three dimensional models
Journal Article
FEBS Journal, ISSN 1742-464X, 06/2007, Volume 274, Issue 12, pp. 3044 - 3054
Bacillus cereus is an opportunistic pathogenic bacterium closely related to Bacillus anthracis, the causative agent of anthrax in mammals. A significant... 
Deacetylase | Bacillus cereus | Rossmann fold | Hydrolase | Zinc-dependent enzyme | MYCOBACTERIUM-TUBERCULOSIS | CHITINOLYTIC PATHWAY | GENOME SEQUENCE | hydrolase | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-D-GLUCOSAMINIDASE | DEACETYLASE MSHB | deacetylase | zinc-dependent enzyme | PROGRAM
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2007, Volume 104, Issue 2, pp. 456 - 461
Journal Article
Journal Article