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Journal Article
Science, ISSN 0036-8075, 2/2011, Volume 331, Issue 6018, pp. 768 - 772
Endocrine tumors such as aldosterone-producing adrenal adenomas (APAs), a cause of severe hypertension, feature constitutive hormone production and... 
Depolarization | Hypertension | Somatic mutation | Cell growth | Hyperaldosteronism | REPORTS | Loss of heterozygosity | Adenoma | Genetic mutation | Sequencing | Tumors | REMEDIABLE ALDOSTERONISM | HUMAN BREAST | COLORECTAL CANCERS | ADRENOCORTICAL-CELLS | MULTIDISCIPLINARY SCIENCES | CONDUCTION | GLOMERULOSA CELLS | IDENTIFICATION | MOLECULAR-BASIS | SELECTIVITY | POTASSIUM CHANNEL | Adrenal Glands - pathology | Potassium - metabolism | Cell Proliferation | Humans | Hyperaldosteronism - pathology | Hyperplasia | Protein Multimerization | Zona Glomerulosa - pathology | Male | Hyperaldosteronism - metabolism | Sodium - metabolism | Aldosterone - metabolism | Adrenocortical Adenoma - genetics | G Protein-Coupled Inwardly-Rectifying Potassium Channels - metabolism | Female | Hypertension - genetics | Adrenal Cortex Neoplasms - metabolism | Cell Line | G Protein-Coupled Inwardly-Rectifying Potassium Channels - chemistry | Hyperaldosteronism - genetics | Mutant Proteins - genetics | Mutant Proteins - metabolism | Zona Glomerulosa - metabolism | Adrenal Cortex Neoplasms - pathology | G Protein-Coupled Inwardly-Rectifying Potassium Channels - genetics | Adrenocortical Adenoma - pathology | Adrenocortical Adenoma - metabolism | Hypertension - metabolism | Adrenal Cortex Neoplasms - genetics | Mutant Proteins - chemistry | Mutation | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
Journal Article
Endocrinology, ISSN 0013-7227, 01/2018, Volume 159, Issue 1, pp. 238 - 247
Hyperaldosteronism is associated with hypertension, cardiac hypertrophy, and congestive heart failure. Steroidogenic factors facilitate aldosterone secretion... 
STEROIDOGENESIS | ALDOSTERONE RELEASE | STEROID-SECRETION | ENDOCRINOLOGY & METABOLISM | RAT ADRENALS | AMINOPEPTIDASE | MEDIUM FLOW-RATE | BLOOD-FLOW | RECEPTORS | GLAND | ENDOTHELIAL NITRIC-OXIDE | Endothelium, Vascular - cytology | Gene Expression Regulation, Enzymologic - drug effects | Abattoirs | Muscle, Smooth, Vascular - metabolism | Zona Glomerulosa - drug effects | Adrenal Cortex - metabolism | Endothelium, Vascular - drug effects | Peptide Fragments - pharmacology | Protease Inhibitors - pharmacology | Aldosterone - metabolism | Cattle | Adrenal Cortex - drug effects | Aminopeptidases - metabolism | Arterioles - cytology | Muscle, Smooth, Vascular - drug effects | Aminopeptidases - genetics | Angiotensin II - pharmacology | Peptide Fragments - metabolism | Angiotensin II - metabolism | Cells, Cultured | Zona Glomerulosa - metabolism | Adrenal Cortex - blood supply | Aminopeptidases - antagonists & inhibitors | Angiotensin II - analogs & derivatives | Angiotensin I - metabolism | Muscle, Smooth, Vascular - cytology | Arterioles - drug effects | Zona Glomerulosa - cytology | Angiotensin III - metabolism | Angiotensin II - chemistry | Animals | Arterioles - metabolism | Endothelium, Vascular - metabolism | Peptide Fragments - antagonists & inhibitors | Vasodilation - drug effects | In Vitro Techniques | Angiotensin I - antagonists & inhibitors | Heart | Enzyme activity | Angiotensin III | Adrenal glands | Eicosanoids | Congestive heart failure | Aldosterone | Arteries | Receptors | Enzymatic activity | Metabolites | Adrenal gland | Angiotensin II | Hypertension | Peptidase | Secretion | Cortex | Mass spectroscopy | Liquid chromatography | Metabolism | Blood flow | Angiotensin | Aminopeptidase | Mass spectrometry | Adrenal metabolism | Hypertrophy | Veins & arteries
Journal Article
Journal Article
Hypertension, ISSN 0194-911X, 11/2010, Volume 56, Issue 5, pp. 885 - 892
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 03/2014, Volume 383, Issue 1-2, pp. 111 - 117
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2018, Volume 115, Issue 52, pp. E12265 - E12274
Adrenal cortex steroids are essential for body homeostasis, and adrenal insufficiency is a life-threatening condition. Adrenal endocrine activity is maintained... 
Progenitors | Adrenal | Differentiation | PKA signaling | EZH2 | FAMILIAL GLUCOCORTICOID DEFICIENCY | PROGENITOR CELLS | differentiation | MULTIDISCIPLINARY SCIENCES | MOUSE | SELF-RENEWAL | DELETION | progenitors | ADRENOCORTICAL DEVELOPMENT | adrenal | ZONA GLOMERULOSA | MUTATIONS | EXPRESSION | REPRESSIVE COMPLEX 2 | Cyclic Nucleotide Phosphodiesterases, Type 3 - genetics | Cyclic AMP-Dependent Protein Kinase RIbeta Subunit - genetics | Adrenal Cortex - metabolism | Zona Glomerulosa - enzymology | Male | Cyclic Nucleotide Phosphodiesterases, Type 7 - genetics | Steroids - metabolism | Female | Cell Differentiation | Cyclic Nucleotide Phosphodiesterases, Type 3 - metabolism | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Zona Fasciculata - enzymology | Adrenal Cortex - enzymology | Signal Transduction | Mice, Inbred C57BL | Cyclic Nucleotide Phosphodiesterases, Type 7 - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 1 - metabolism | Zona Glomerulosa - metabolism | Zona Fasciculata - cytology | Zona Glomerulosa - cytology | Mice, Knockout | Cyclic AMP-Dependent Protein Kinase RIbeta Subunit - metabolism | Animals | Zona Fasciculata - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 1 - genetics | Methyltransferases | Adrenal glands | Physiological aspects | Physiological research | Cellular signal transduction | Research | Protein kinases | Protein kinase A | Ca2 /calmodulin-dependent phosphodiesterase | Glucocorticoids | Cortex | Adrenal cortex | Differentiation (biology) | Homeostasis | Cell differentiation | Ablation | Progenitor cells | Signaling | Adrenocorticotropic hormone | Differential equations | Cells (biology) | Stem cells | Histone methyltransferase | Steroid hormones | Steroids | Animal genetics | Cyclic Nucleotide Phosphodiesterases, Type 1 | Genomics | Cyclic Nucleotide Phosphodiesterases, Type 3 | Embryology and Organogenesis | Life Sciences | Zona Glomerulosa | Zona Fasciculata | Cyclic AMP-Dependent Protein Kinase RIbeta Subunit | Genetics | Endocrinology and metabolism | Adrenal Cortex | Biochemistry, Molecular Biology | Enhancer of Zeste Homolog 2 Protein | Human health and pathology | Development Biology | Cyclic Nucleotide Phosphodiesterases, Type 7 | Molecular biology | Cancer | Biological Sciences | PNAS Plus
Journal Article