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The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 4, pp. 338 - 351
Journal Article
CANCER CELL, ISSN 1535-6108, 07/2017, Volume 32, Issue 1, pp. 6 - 8
Two papers published recently in the New England Journal of Medicine describe the utility of abiraterone acetate, an androgen biosynthesis inhibitor, in the... 
ONCOLOGY | ABIRATERONE | CELL BIOLOGY
Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 533, Issue 7604, pp. 547 - 551
Abiraterone blocks androgen synthesis and prolongs survival in patients with castration-resistant prostate cancer, which is otherwise driven by intratumoral... 
ACTIVATION | CYP17A1 INHIBITION | RAT | MULTIDISCIPLINARY SCIENCES | ANDROGEN-RECEPTOR | BIOLOGY | MEN | RESISTANCE | STEROID 5-ALPHA-REDUCTASE | DIHYDROTESTOSTERONE | DEHYDROGENASE | Prostatic Neoplasms - metabolism | Dutasteride - therapeutic use | Humans | Receptors, Androgen - metabolism | Androgens - biosynthesis | Male | Androstenes - pharmacology | Abiraterone Acetate - administration & dosage | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | Oxidation-Reduction - drug effects | Prostatic Neoplasms - blood | Androstenes - blood | Prostatic Neoplasms - drug therapy | Administration, Oral | Prostatic Neoplasms, Castration-Resistant - blood | Androgen Antagonists - pharmacology | 5-alpha Reductase Inhibitors - therapeutic use | Abiraterone Acetate - therapeutic use | Dutasteride - pharmacology | Prostatic Neoplasms, Castration-Resistant - drug therapy | Androstenes - administration & dosage | Prostatic Neoplasms, Castration-Resistant - metabolism | Disease Progression | Xenograft Model Antitumor Assays | Animals | Abiraterone Acetate - blood | Abiraterone Acetate - metabolism | 5-alpha Reductase Inhibitors - pharmacology | Androgen Antagonists - therapeutic use | Androstenes - metabolism | Cell Line, Tumor | Mice | Physiological aspects | Prostate cancer | Care and treatment | Enzymes | Androgens | Metabolites | Oxidation | Metabolism | Gene expression | Steroids | Index Medicus
Journal Article
European Urology, ISSN 0302-2838, 2014, Volume 68, Issue 1, pp. 147 - 153
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 12/2015, Volume 55, Issue 12, pp. 1406 - 1414
Journal Article
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 4, pp. 352 - 360
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 10/2018, Volume 36, Issue 30, pp. 3064 - 3065
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 10/2017, Volume 80, Issue 4, pp. 723 - 728
Journal Article
Annals of Oncology, ISSN 0923-7534, 07/2018, Volume 29, Issue 7, pp. 1554 - 1560
Abstract Background The development of treatment response and surrogate biomarkers for advanced prostate cancer care is an unmet clinical need. Patients with... 
Castration-resistant prostate cancer | Progression | Treatment outcome | Chemotherapy | Abiraterone | Circulating tumour cells | SURVIVAL | abiraterone | ONCOLOGY | CLINICAL-TRIALS | progression | circulating tumour cells | ABIRATERONE ACETATE | castration-resistant prostate cancer | treatment outcome | chemotherapy | DOCETAXEL | ANTIGEN
Journal Article
European Urology, ISSN 0302-2838, 2016, Volume 70, Issue 5, pp. 718 - 721
Abstract Coadministration of docetaxel and abiraterone acetate plus prednisone (AA + P) may benefit patients with metastatic castration-resistant prostate... 
Urology | Metastatic castration-resistant prostate cancer | Toxicity | Abiraterone acetate | Combination | Androgen receptor | Docetaxel | Safety | Drug-drug interaction | Pharmacokinetics | prostate cancer | UROLOGY & NEPHROLOGY | Metastatic castration-resistant | Humans | Middle Aged | Male | Antineoplastic Agents - administration & dosage | Drug Monitoring - methods | Prostatic Neoplasms, Castration-Resistant - pathology | Dose-Response Relationship, Drug | Abiraterone Acetate - administration & dosage | Neoplasm Metastasis | Antineoplastic Agents - adverse effects | Antineoplastic Agents - pharmacokinetics | Abiraterone Acetate - pharmacokinetics | Taxoids - adverse effects | Prednisone - administration & dosage | Prednisone - adverse effects | Prostatic Neoplasms, Castration-Resistant - blood | Abiraterone Acetate - adverse effects | Antineoplastic Combined Chemotherapy Protocols | Treatment Outcome | Prostatic Neoplasms, Castration-Resistant - drug therapy | Disease Progression | Prostate-Specific Antigen - blood | Taxoids - pharmacokinetics | Disease-Free Survival | Taxoids - administration & dosage | Prednisone - pharmacokinetics | Aged | Neoplasm Staging | Medical research | Care and treatment | Chemotherapy | Corticosteroids | Medicine, Experimental | Prednisone | Metastasis | Prostate cancer | Acetates | Cancer | Steroids | Index Medicus
Journal Article