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Blood Reviews, ISSN 0268-960X, 06/2002, Volume 16, Issue 2, pp. 97 - 110
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2000, Volume 97, Issue 10, pp. 5255 - 5260
Protease-activated receptor 2 (PAR2) is expressed by vascular endothelial cells and other cells in which its function and physiological activator(s) are... 
Hydrolysis | Biological Sciences | Receptors | Calcium | Cell lines | Coagulation | Agonists | Complementary RNA | Zymogens | Endothelial cells | Oocytes | CANINE KIDNEY-CELLS | BLOOD-COAGULATION | PATHWAY | MULTIDISCIPLINARY SCIENCES | KINASE | MOLECULAR-CLONING | THROMBIN RECEPTOR | EXPRESSION | HEMOSTASIS | BINDING | HUMAN ENDOTHELIAL-CELLS | Endothelium, Vascular - cytology | Vascular Endothelial Growth Factor A | Calcium - metabolism | Vascular Endothelial Growth Factors | Humans | Endothelium, Vascular - drug effects | Endothelial Growth Factors - pharmacology | Receptors, Thrombin - chemistry | Endothelium, Vascular - physiology | Receptor, PAR-2 | Transfection | Female | Phosphatidylinositols - metabolism | Lymphokines - pharmacology | Recombinant Proteins - metabolism | Cell Line | Protein Structure, Secondary | Xenopus laevis | Keratinocytes | Recombinant Proteins - chemistry | Cytoplasm - physiology | Factor VIIa - metabolism | Factor Xa - metabolism | Mice, Knockout | Tumor Necrosis Factor-alpha - pharmacology | Animals | Oocytes - physiology | Receptors, Thrombin - metabolism | Factor X - metabolism | Mice | Enzyme Activation | Kinetics | Thromboplastin - metabolism | Research | Blood coagulation factors | Proteases | Cytology | Endothelium | protease-activated receptor 4 | protease-activated receptor 3 | protease-activated receptor 2 | protease-activated receptor 1 | tissue factor | coagulation factor VIIa | zymogen factor X
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2009, Volume 119, Issue 9, pp. 2550 - 2563
Uncontrolled activation of the coagulation cascade contributes to the pathophysiology of several conditions, including acute and chronic lung diseases.... 
MEDICINE, RESEARCH & EXPERIMENTAL | GROWTH-FACTOR-BETA | BLOOD-COAGULATION | THROMBUS FORMATION | GENE-EXPRESSION | IDIOPATHIC PULMONARY-FIBROSIS | PROTEASE-ACTIVATED RECEPTOR-1 | TISSUE FACTOR EXPRESSION | SUSCEPTIBILITY GENES | RESPIRATORY-DISTRESS-SYNDROME | BRONCHOALVEOLAR LAVAGE | Up-Regulation | Lung Injury - pathology | Factor Xa Inhibitors | Receptor, PAR-1 - metabolism | Humans | Middle Aged | Actins - metabolism | Male | Pulmonary Fibrosis - blood | Idiopathic Pulmonary Fibrosis - blood | RNA, Messenger - metabolism | Case-Control Studies | Idiopathic Pulmonary Fibrosis - metabolism | Idiopathic Pulmonary Fibrosis - etiology | Base Sequence | Lung Injury - metabolism | Adult | Female | Cell Differentiation | Pulmonary Fibrosis - metabolism | Receptors, Vitronectin - metabolism | Pulmonary Fibrosis - etiology | Bleomycin - toxicity | Fibroblasts - metabolism | Gene Expression | Factor Xa - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Pulmonary Fibrosis - pathology | Fibroblasts - pathology | Factor Xa - metabolism | Animals | Transforming Growth Factor beta - genetics | Models, Biological | Fibroblasts - drug effects | Idiopathic Pulmonary Fibrosis - pathology | Aged | Mice | Transforming Growth Factor beta - metabolism | Transforming growth factors | Lung diseases | Integrins | Index Medicus | Abridged Index Medicus
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 05/2018, Volume 118, Issue 5, pp. 830 - 841
Abstract The link between factor (F)VIII and FX is essential for optimum activity of the tenase complex. The interactive site(s) in FVIII for FX remains to be... 
Coagulation and Fibrinolysis | A2 domain | factor VIII | factor X | tenase complex | binding site | ANTIBODIES | FACTOR-IXA | ACTIVATED PROTEIN-C | CRYSTAL-STRUCTURE | LIGHT-CHAIN | A1 SUBUNIT | VON-WILLEBRAND-FACTOR | REGION | VONWILLEBRAND-FACTOR | BINDING-SITE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 02/2018, Volume 820, pp. 222 - 228
Journal Article
Journal Article
AJP - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 01/2006, Volume 290, Issue 1, pp. L21 - L31
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2010, Volume 285, Issue 45, pp. 34803 - 34812
We recently demonstrated that the Gla domain-dependent interaction of protein C with endothelial protein C receptor (EPCR) leads to dissociation of the... 
ACTIVATION | BLOOD-COAGULATION | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | THROMBIN-THROMBOMODULIN COMPLEX | FACTOR-KAPPA-B | MOLECULAR-CLONING | LIGAND | FACTOR-XA | EXPRESSION | TISSUE FACTOR | Endothelial Protein C Receptor | Receptor, PAR-1 - metabolism | Humans | Receptor, PAR-2 - metabolism | Enzyme Precursors - genetics | Enzyme Precursors - pharmacology | Mutation, Missense | Antigens, CD - genetics | Protein C - pharmacology | Antigens, CD - metabolism | Receptor, PAR-2 - genetics | Protein Structure, Tertiary | Cell Line | Factor Xa - genetics | Endothelial Cells - metabolism | Receptors, Cell Surface - agonists | Caveolin 1 - genetics | Receptors, Cell Surface - metabolism | Enzyme Activation - drug effects | Factor VIIa - metabolism | Factor Xa - metabolism | Receptor, PAR-1 - genetics | Caveolin 1 - metabolism | Enzyme Precursors - metabolism | Factor Xa - pharmacology | Signal Transduction - drug effects | Endothelial Cells - cytology | Factor VIIa - genetics | Signal Transduction - physiology | Protein C - metabolism | Enzyme Activation - physiology | Protein C - genetics | Amino Acid Substitution | Receptors, Cell Surface - genetics | Receptor Regulation | Protease-activated Receptors | Factor X | Signal Transduction | Blood Coagulation Factors | G-protein Coupled Receptors (GPCR) | Thrombin | Activated Protein C | EPCR | Endothelium
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 11/2014, Volume 229, Issue 11, pp. 1673 - 1680
Journal Article
Journal Article