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Blood, ISSN 0006-4971, 08/2015, Volume 126, Issue 8, pp. 943 - 949
Journal Article
Cancer Cell, ISSN 1535-6108, 2006, Volume 10, Issue 1, pp. 65 - 75
Tyrosine kinases are aberrantly activated in numerous malignancies, including acute myeloid leukemia (AML). To identify tyrosine kinases activated in AML, we... 
CELLCYCLE | ALLOGRAFT-REJECTION | POLYCYTHEMIA-VERA | MYELOPROLIFERATIVE DISORDERS | ONCOLOGY | CONSTITUTIVE ACTIVATION | TYROSINE KINASE JAK2 | PSEUDOKINASE DOMAIN | ACUTE MYELOID-LEUKEMIA | JANUS KINASE | CELL-LINES | MICE LACKING JAK3 | CELL BIOLOGY | RNA, Small Interfering - genetics | Apoptosis - drug effects | Protein-Tyrosine Kinases - metabolism | Humans | TYK2 Kinase | Janus Kinase 2 | Janus Kinase 3 | Protein-Tyrosine Kinases - genetics | Leukemia, Megakaryoblastic, Acute - genetics | Phosphorylation - drug effects | Leukemia, Megakaryoblastic, Acute - metabolism | Leukemia, Experimental - genetics | Leukemia, Experimental - pathology | Proto-Oncogene Proteins - metabolism | Cell Survival - drug effects | Mice, Inbred C57BL | Mutant Proteins - genetics | Models, Molecular | Mutant Proteins - metabolism | Proto-Oncogene Proteins - genetics | Protein Structure, Tertiary - genetics | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Animals | Mutant Proteins - chemistry | Alleles | K562 Cells | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Benzamides | Leukemia, Megakaryoblastic, Acute - pathology | Leukemia, Experimental - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | Tyrosine | Allelomorphism | Proteins | Analysis | Oncology, Experimental | Research | Mass spectrometry | Phosphotransferases | Cancer
Journal Article
Genes and Development, ISSN 0890-9369, 03/2010, Volume 24, Issue 5, pp. 478 - 490
Journal Article
Blood, ISSN 0006-4971, 09/2015, Volume 126, Issue 13, pp. 1575 - 1584
Journal Article
Cancer Cell, ISSN 1535-6108, 11/2012, Volume 22, Issue 5, pp. 683 - 697
To define the mutation spectrum in non-Down syndrome acute megakaryoblastic leukemia (non-DS-AMKL), we performed transcriptome sequencing on diagnostic blasts... 
ONCOLOGY-GROUP | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | ZINC-FINGER PROTEIN | GLI PROTEINS | FUNCTIONAL-CHARACTERIZATION | ACUTE MYELOID-LEUKEMIA | DIFFERENTIATION | ACUTE MEGAKARYOCYTIC LEUKEMIA | CELL-LINE | GENETIC ALTERATIONS | CELL BIOLOGY | Oncogene Proteins, Fusion - metabolism | Prognosis | Humans | Leukemia, Megakaryoblastic, Acute - classification | Recombinant Fusion Proteins - physiology | Gene Expression Profiling | Chromosome Inversion | Recombinant Fusion Proteins - metabolism | Oncogene Proteins, Fusion - physiology | Bone Morphogenetic Proteins - metabolism | Tumor Suppressor Proteins - genetics | Leukemia, Megakaryoblastic, Acute - genetics | Child | Drosophila - genetics | Leukemia, Megakaryoblastic, Acute - diagnosis | Signal Transduction | Repressor Proteins - genetics | Animals | Sequence Analysis, RNA | Oncogene Proteins, Fusion - genetics | Chromosomes, Human, Pair 16 | Recombinant Fusion Proteins - genetics | Drosophila - growth & development | Mice | Kruppel-Like Transcription Factors - genetics | Pediatrics | Medical colleges | Oncology, Experimental | Analysis | Bone marrow | Transplantation | Research | Children | Health aspects | Biometry | Cancer | Leukemia, Megakaryoblastic, Acute/classification | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Drosophila/genetics | Bone Morphogenetic Proteins/metabolism | Kruppel-Like Transcription Factors/genetics | Oncogene Proteins, Fusion/genetics | Recombinant Fusion Proteins/genetics | Basic Medicine | Repressor Proteins/genetics | Tumor Suppressor Proteins/genetics | Clinical Medicine | Medicinska och farmaceutiska grundvetenskaper | Cancer and Oncology | Cancer och onkologi
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 03/2017, Volume 49, Issue 3, pp. 451 - 456
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2012, Volume 122, Issue 3, pp. 948 - 962
Individuals with Down syndrome (DS; also known as trisomy 21) have a markedly increased risk of leukemia in childhood but a decreased risk of solid tumors in... 
MEDICINE, RESEARCH & EXPERIMENTAL |