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Biomaterials, ISSN 0142-9612, 2011, Volume 32, Issue 23, pp. 5438 - 5458
Abstract Oxidative stress is a major component of harmful cascades activated in neurodegenerative disorders. We sought to elucidate possible effects of... 
Advanced Basic Science | Dentistry | Oxidative stress | Mitochondria | Caspase-dependent apoptosis | Endoplasmic reticulum | Alginate oligosaccharide | PC12 cells | SIGNALING PATHWAYS | ACTIVATION | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | CASCADES | P53 | DISEASES | BAX | CYTOCHROME-C RELEASE | PROTEINS | BINDING | MEMBRANE PERMEABILIZATION | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Calcium - metabolism | Glutathione - metabolism | Amyloid beta-Peptides - pharmacology | Oxidative Stress - physiology | Caspase 3 - metabolism | Endoplasmic Reticulum - metabolism | NF-kappa B - metabolism | Neurons - cytology | Peptide Fragments - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | PC12 Cells | Oligosaccharides - pharmacology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Apoptosis Inducing Factor - pharmacology | Cell Nucleus - metabolism | Endoplasmic Reticulum - drug effects | Oxidation-Reduction - drug effects | Neurons - metabolism | Phosphorylation - drug effects | Glucuronic Acid - chemistry | Neurons - drug effects | Polysaccharide-Lyases - chemistry | Apoptosis Inducing Factor - metabolism | Cell Survival - drug effects | Cytochromes c - metabolism | Hydrogen Peroxide - pharmacology | Tumor Suppressor Protein p53 - metabolism | bcl-2-Associated X Protein - metabolism | Rats | Mitochondria - metabolism | Caspase 12 - metabolism | Hexuronic Acids - chemistry | Mitochondria - drug effects | HSP70 Heat-Shock Proteins - metabolism | Cell Shape - drug effects | Poly(ADP-ribose) Polymerases - metabolism | Animals | Models, Biological | Alginates - chemistry | NF-E2-Related Factor 2 - metabolism | HSP90 Heat-Shock Proteins - metabolism | Apoptosis - physiology | Oxidative Stress - drug effects | Cell Nucleus - drug effects | Neurosciences | Nervous system diseases | Biological products | Hydrogen peroxide | Heat shock proteins | Nerve growth factor | Superoxide | Mitochondrial DNA | Biochemistry | Antioxidants | Tumor proteins | Protein kinases | Alzheimer's disease | Apoptosis | Stresses | Surgical implants | Biomedical materials | Cell death | Cascades | Blocking | Activation | Kinases
Journal Article
Science, ISSN 0036-8075, 1/2012, Volume 335, Issue 6066, pp. 308 - 313
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 505, Issue 7482, pp. 239 - 243
Journal Article
Journal of Biomedical Materials Research Part A, ISSN 1549-3296, 05/2006, Volume 77A, Issue 2, pp. 242 - 252
Development of biosynthetic conduits carrying extracellular matrix molecules and cell lines expressing neurotrophic growth factors represents a novel and... 
cell proliferation | fibronectin | cell culture | nerve tissue engineering | bioprosthesis | Cell proliferation | Cell culture | Bioprosthesis | Fibronectin | Nerve tissue engineering | PERIPHERAL-NERVE REGENERATION | STEM-CELLS | MATERIALS SCIENCE, BIOMATERIALS | RAT SCHWANN-CELLS | INJURED SPINAL-CORD | ADULT RATS | ENGINEERING, BIOMEDICAL | OLFACTORY ENSHEATHING GLIA | HUMAN BONE-MARROW | GROWTH-FACTORS | MARROW STROMAL CELLS | BASEMENT-MEMBRANE | Biocompatible Materials - metabolism | Stromal Cells - transplantation | Biocompatible Materials - chemistry | Nerve Regeneration - physiology | Collagen - chemistry | Ganglia, Spinal - cytology | Alginates - metabolism | Proteoglycans - chemistry | Schwann Cells - cytology | Neurites - ultrastructure | Cell Shape | Female | Hydrogels - metabolism | Olfactory Bulb - cytology | Animals, Newborn | Bone Marrow Cells - cytology | Stromal Cells - metabolism | Cells, Cultured | Proteoglycans - metabolism | Rats | Schwann Cells - transplantation | Materials Testing | Neurites - metabolism | Schwann Cells - metabolism | Rats, Sprague-Dawley | Fibronectins - metabolism | Collagen - metabolism | Animals | Alginates - chemistry | Laminin - chemistry | Laminin - metabolism | Bone Marrow Cells - metabolism | Drug Combinations | Hydrogels - chemistry | Stromal Cells - cytology | Cell Transplantation - methods | Proteoglycans/chemistry/metabolism | Cell Transplantation/methods | Collagen/chemistry/metabolism | Nerve Regeneration/physiology | Cells; Cultured | Bone Marrow Cells/cytology/metabolism | Rats; Sprague-Dawley | Animals; Newborn | Hydrogels/chemistry/metabolism | Biocompatible Materials/chemistry/metabolism | Stromal Cells/cytology/metabolism/transplantation | Alginates/chemistry/metabolism | Ganglia; Spinal/cytology | Olfactory Bulb/cytology | Neurites/metabolism/ultrastructure | Fibronectins/metabolism | Schwann Cells/cytology/metabolism/transplantation | Laminin/chemistry/metabolism
Journal Article
Marine Drugs, ISSN 1660-3397, 02/2017, Volume 15, Issue 2, pp. 37 - 37
Recently, we identified an alginate-assimilating gene cluster in the genome of Flavobacterium sp. strain UMI-01, a member of Bacteroidetes. Alginate lyase... 
2-keto-3-deoxy-D-gluconate (KDG) kinase/2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase | 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) metabolism | Proteobacteria | Flavobacterium | Alginate-derived products | Bacteroidetes | Alginate degradation | alginate-derived products | CHEMISTRY, MEDICINAL | alginate degradation | ENTNER-DOUDOROFF PATHWAY | 2-keto-3-deoxy-D-gluconate (KDG) kinase | ESCHERICHIA-COLI | 4-DEOXY-L-ERYTHRO-5-HEXOSEULOSE URONIC-ACID | 2-keto-3deoxy-6-phosphogluconate (KDPG) aldolase | METABOLISM | HALIOTIS-DISCUS-HANNAI | 2-KETO-3-DEOXYGLUCONATE KINASE | CDNA CLONING | EXPRESSION | 2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE KDPG ALDOLASE | OLIGOALGINATE LYASE | Amino Acid Sequence | Proteobacteria - metabolism | Oxidoreductases - metabolism | Glucuronic Acid - metabolism | Phylogeny | Uronic Acids - metabolism | Alginates - metabolism | Gluconates - metabolism | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Sequence Alignment | Bacteroidetes - metabolism | Escherichia coli - metabolism | Aldehyde-Lyases - metabolism | Hexuronic Acids - metabolism | Flavobacterium - metabolism | 4-deoxy | l-erythro-5-hexoseulose uronic acid (DEH) metabolism">">l-erythro-5-hexoseulose uronic acid (DEH) metabolism | d-gluconate (KDG) kinase">">d-gluconate (KDG) kinase | 2-keto-3-deoxy | 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 10/2012, Volume 56, Issue 10, pp. 5040 - 5045
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
EUROPE | TN916 | ELEMENTS | TETRACYCLINE RESISTANCE GENE | BACTERIA | ANTIBIOTIC USE | ESCHERICHIA-COLI | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | PNEUMOCOCCI | ERYTHROMYCIN RESISTANCE | Biofilms - drug effects | Streptococcus pneumoniae - drug effects | Streptococcus pneumoniae - ultrastructure | Tetracycline Resistance | Hexuronic Acids - chemistry | Acinetobacter - ultrastructure | Acinetobacter - drug effects | Oligosaccharides - pharmacology | Microscopy, Confocal | Oligosaccharides - chemical synthesis | Pseudomonas - ultrastructure | Pseudomonas - drug effects | Burkholderia - metabolism | Streptococcus pneumoniae - metabolism | Acinetobacter - metabolism | Alginates - chemistry | Oligosaccharides - chemistry | Microscopy, Atomic Force | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Burkholderia - ultrastructure | Glucuronic Acid - chemistry | Pseudomonas - metabolism | Burkholderia - drug effects | Glucuronic Acid/chemistry | Biofilms/drug effects | Pseudomonas/drug effects | Streptococcus pneumoniae/metabolism | Alginates/chemistry | Burkholderia/drug effects | Anti-Bacterial Agents/pharmacology | Bacteriology | Acinetobacter/ultrastructure | Hexuronic Acids/chemistry | Life Sciences | Burkholderia/metabolism | Microbiology and Parasitology | Bacterial Proteins/metabolism | Oligosaccharides/chemical synthesis | Acinetobacter/metabolism | Acinetobacter/drug effects | Burkholderia/ultrastructure | Mechanisms of Resistance
Journal Article
Osteoarthritis and Cartilage, ISSN 1063-4584, 2013, Volume 21, Issue 12, pp. 1913 - 1923
Summary Objective The aim of this study was to investigate the link between the hypertrophic phenotype of chondrocytes and angiogenesis in osteoarthritis (OA)... 
Rheumatology | Angiogenesis | Bone sialoprotein | Chondrocyte hypertrophy | Osteoarthritis | RHEUMATOLOGY | METALLOPROTEINASES | OSTEOCHONDRAL JUNCTION | ARTICULAR-CARTILAGE | SIALOPROTEIN | ENDOTHELIAL-CELLS | GROWTH-FACTOR | BONE | DIFFERENTIATION | ORTHOPEDICS | EXPRESSION | ALGINATE BEADS | Osteopontin - genetics | Up-Regulation | Thrombospondins - genetics | Humans | Osteopontin - metabolism | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-1 - metabolism | Vascular Endothelial Growth Factor A - genetics | Osteoarthritis - physiopathology | Intercellular Signaling Peptides and Proteins - metabolism | Cartilage, Articular - metabolism | Thrombospondin 1 - genetics | Fibroblast Growth Factor 2 - metabolism | Neovascularization, Pathologic - physiopathology | Membrane Proteins - metabolism | Chondrocytes - metabolism | Endothelial Cells - physiology | Chondrocytes - pathology | Nerve Growth Factor - metabolism | Cartilage, Articular - cytology | Matrix Metalloproteinase 2 - metabolism | Membrane Proteins - genetics | Cells, Cultured | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Osteoarthritis - metabolism | Nerve Growth Factor - genetics | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion | Osteoarthritis - genetics | Angiopoietin-1 - genetics | Matrix Metalloproteinase 2 - genetics | Fibroblast Growth Factor 2 - genetics | Integrin-Binding Sialoprotein - genetics | Neovascularization, Pathologic - genetics | Neovascularization, Pathologic - metabolism | Thrombospondin 1 - metabolism | Integrin-Binding Sialoprotein - metabolism | Thrombospondins - metabolism | Cell Movement | Hypertrophy
Journal Article
Biomaterials, ISSN 0142-9612, 2011, Volume 32, Issue 21, pp. 4903 - 4913
Journal Article
1942, Research report (U.S. Fish and Wildlife Service), Volume 4., 9
Algin, a salt of alginic acid extracted from kelp, and gelatin produced from animal bones and skins, are used as stabilizing agents in the manufacture of ice... 
metabolism | alginic acid | nutritive value | alginates | gels
Book
Nature Materials, ISSN 1476-1122, 06/2014, Volume 13, Issue 10, pp. 970 - 978
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 3/2013, Volume 30, Issue 3, pp. 721 - 734
To evaluate the efficacy of mucoadhesive insulin-loaded whey protein (WP) /alginate (ALG) microparticles (MP) for oral insulin administration.Insulin-loaded... 
Biochemistry, general | Biomedical Engineering | alginate | whey protein | Biomedicine | oral administration | insulin | microspheres | Pharmacy | Medical Law | Pharmacology/Toxicology | POLYMERS | PROTECTION | SUPERPOROUS HYDROGEL | PEPTIDE DRUG-DELIVERY | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | TRANSPORT | GEL BEADS | PHARMACOLOGY & PHARMACY | ABSORPTION | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Rats, Wistar | Hypoglycemic Agents - metabolism | Glucuronic Acid - metabolism | Male | Alginates - metabolism | Drug Carriers - chemistry | Microspheres | Milk Proteins - chemistry | Hypoglycemic Agents - administration & dosage | Duodenum - metabolism | Whey Proteins | Glucuronic Acid - chemistry | Hydrogel, Polyethylene Glycol Dimethacrylate - metabolism | Milk Proteins - metabolism | Insulin - pharmacology | Rabbits | Drug Carriers - metabolism | Hypoglycemic Agents - pharmacokinetics | Administration, Oral | Rats | Insulin - administration & dosage | Hexuronic Acids - chemistry | Hypoglycemic Agents - pharmacology | Insulin - metabolism | Animals | Duodenum - ultrastructure | Alginates - chemistry | Tissue Adhesives - metabolism | Insulin - pharmacokinetics | Tissue Adhesives - chemistry | Hexuronic Acids - metabolism | Animal experimentation | Glucose metabolism | Milk proteins | Adsorption | Blood sugar | Functional foods | Natural foods | Insulin | Diabetes therapy | Proteins | Drug delivery systems | Pharmacology
Journal Article