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Journal of internal medicine, ISSN 0954-6820, 10/2014, Volume 276, Issue 4, pp. 311 - 335
hereditary disorder | therapy | AAT deficiency | alpha‐1 antitrypsin | alpha-1 antitrypsin | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Genetic Therapy | Injections, Intravenous | Prevalence | alpha 1-Antitrypsin - blood | Humans | alpha 1-Antitrypsin Deficiency - drug therapy | alpha 1-Antitrypsin - physiology | Genotype | alpha 1-Antitrypsin Deficiency - epidemiology | alpha 1-Antitrypsin Deficiency - diagnosis | alpha 1-Antitrypsin - therapeutic use | Animals | alpha 1-Antitrypsin Deficiency - complications | Health | Genetic engineering | Liver diseases | Formulations | Patents | Phenotypes | Genetic disorders | Low concentrations | Immunomodulation | Liver | Lung diseases | Transgenic | Pharmacology | Genetic screening | Molecular chains | Cirrhosis | Vasculitis | Patent applications | Obstructive lung disease | Chronic obstructive pulmonary disease | Adults | Children | Systemic vasculitis | Genetic counselling | Genotypes | Index Medicus
Journal Article
Transplantation proceedings, ISSN 0041-1345, 10/2019, Volume 51, Issue 8, pp. 2814 - 2822
Inflammation - pathology | Kidney - blood supply | Cytokines - metabolism | Reperfusion Injury - pathology | Apoptosis - drug effects | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Blood Urea Nitrogen | Mice, Inbred C57BL | Male | Serine Proteinase Inhibitors - therapeutic use | alpha 1-Antitrypsin - therapeutic use | Animals | Reperfusion Injury - prevention & control | Creatinine - blood | alpha 1-Antitrypsin - pharmacology | Mice | Serine Proteinase Inhibitors - pharmacology | Disease Models, Animal | Urea | Interleukins | Proteases | Analysis | Inflammation | Alpha 1-antitrypsin | Reperfusion injury | Index Medicus
Journal Article
Thorax, ISSN 0040-6376, 08/2012, Volume 67, Issue 8, pp. 669 - 674
Cardiology. Vascular system | Biological and medical sciences | Medical sciences | Pneumology | alpha 1-Antitrypsin Deficiency - genetics | alpha 1-Antitrypsin - genetics | Cross-Sectional Studies | alpha 1-Antitrypsin - blood | Gene Frequency | Humans | Middle Aged | Genotype | Male | Reference Values | alpha 1-Antitrypsin Deficiency - epidemiology | alpha 1-Antitrypsin Deficiency - diagnosis | Young Adult | alpha 1-Antitrypsin Deficiency - blood | Switzerland - epidemiology | Adolescent | Adult | Female | Polymorphism, Single Nucleotide | Index Medicus
Journal Article
Digestive and liver disease, ISSN 1590-8658, 2016, Volume 48, Issue 12, pp. 1510 - 1511
Journal Article
The Journal of immunology (1950), ISSN 0022-1767, 04/2019, Volume 202, Issue 8, pp. 2240 - 2253
Life Sciences & Biomedicine | Immunology | Science & Technology | alpha 1-Antitrypsin Deficiency - genetics | alpha 1-Antitrypsin - genetics | alpha 1-Antitrypsin - blood | Humans | Liver - metabolism | Male | alpha 1-Antitrypsin Deficiency - immunology | Codon, Nonsense | alpha 1-Antitrypsin Deficiency - blood | Liver - immunology | Alleles | Adult | Female | Induced Pluripotent Stem Cells - immunology | alpha 1-Antitrypsin - immunology | Induced Pluripotent Stem Cells - metabolism | Index Medicus | Abridged Index Medicus | Immune Regulation
Journal Article
Respiratory medicine, ISSN 0954-6111, 03/2019, Volume 148, p. 60
Journal Article
Orphanet journal of rare diseases, ISSN 1750-1172, 2008, Volume 3, Issue 1, pp. 16 - 16
alpha 1-Antitrypsin Deficiency - genetics | Pulmonary Emphysema - physiopathology | Prevalence | alpha 1-Antitrypsin - genetics | Humans | alpha 1-Antitrypsin Deficiency - epidemiology | Liver Cirrhosis - therapy | Pulmonary Emphysema - therapy | alpha 1-Antitrypsin Deficiency - diagnosis | alpha 1-Antitrypsin - chemistry | alpha 1-Antitrypsin Deficiency - physiopathology | Adult | alpha 1-Antitrypsin - metabolism | Liver Cirrhosis - physiopathology | Mutation | Infant, Newborn | Causes of | Care and treatment | Prognosis | Diagnosis | Alpha 1-antitrypsin deficiency | Index Medicus
Journal Article
8.
Alpha-1 antitrypsin-deficient macrophages have increased matriptase-mediated proteolytic activity
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 08/2017, Volume 57, Issue 2, pp. 238 - 247
Alpha-1 antitrypsin deficiency | Matriptase | Macrophages | Extracellular matrix degradation | Matrix metalloproteinase-14 | Respiratory System | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Up-Regulation | Pulmonary Emphysema - etiology | Humans | Middle Aged | Serine Endopeptidases - physiology | Endoplasmic Reticulum - metabolism | Male | Young Adult | Monocytes - pathology | Serine Endopeptidases - genetics | Adult | Female | Extracellular Matrix Proteins - metabolism | alpha 1-Antitrypsin Deficiency - genetics | Pulmonary Emphysema - physiopathology | alpha 1-Antitrypsin - genetics | Macrophages - pathology | Serine Endopeptidases - biosynthesis | Cells, Cultured | Enzyme Induction | Matrix Metalloproteinase 14 - metabolism | Macrophages, Alveolar - enzymology | alpha 1-Antitrypsin Deficiency - blood | alpha 1-Antitrypsin Deficiency - complications | alpha 1-Antitrypsin - pharmacology | alpha 1-Antitrypsin Deficiency - physiopathology | Macrophages - drug effects | Aged | alpha 1-Antitrypsin - metabolism | Enzyme Activation | Mutation | Pulmonary Emphysema - enzymology | Disease | Serine | Neutrophils | Arthritis | Leukocytes (neutrophilic) | Matrix metalloproteinase | Autophagy | Cell surface | Proteases | Proteolysis | Extracellular matrix | Metalloproteinase | Serine proteinase | Chronic obstructive pulmonary disease | Elastase | Supplementation | Intracellular | Alveoli | Emphysema | Endoplasmic reticulum
Journal Article
Rheumatology international, ISSN 0172-8172, 4/2014, Volume 34, Issue 4, pp. 553 - 558
Alpha 1-antitrypsin | Medicine & Public Health | Antineutrophil cytoplasmic antibody | Wegener’s granulomatosis | Rheumatology | Proteinase 3 | Wegener's granulomatosis | Life Sciences & Biomedicine | Science & Technology | Granulomatosis with Polyangiitis - diagnosis | Prevalence | Prognosis | alpha 1-Antitrypsin - blood | Down-Regulation | Humans | Middle Aged | Granulomatosis with Polyangiitis - epidemiology | Male | alpha 1-Antitrypsin Deficiency - epidemiology | Biomarkers - blood | Granulomatosis with Polyangiitis - blood | alpha 1-Antitrypsin Deficiency - diagnosis | Young Adult | alpha 1-Antitrypsin Deficiency - blood | Phenotype | Adolescent | Adult | Female | Aged | Retrospective Studies | Iran - epidemiology | Enzymes | Autoantibodies | Enzyme-linked immunosorbent assay | Index Medicus
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 09/2019, Volume 157, Issue 3, pp. 705 - 719.e18
Rare Liver Disease | ALT | AST | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Liver - pathology | Age Factors | Humans | Middle Aged | Male | Case-Control Studies | Liver - diagnostic imaging | Adult | Female | alpha 1-Antitrypsin Deficiency - enzymology | Liver Function Tests | alpha 1-Antitrypsin Deficiency - genetics | Liver Cirrhosis - etiology | Genetic Predisposition to Disease | Liver Cirrhosis - diagnosis | alpha 1-Antitrypsin - genetics | Fatty Liver - blood | Europe | Liver - metabolism | Risk Factors | Lipid Metabolism | Mice, Transgenic | Liver Cirrhosis - blood | alpha 1-Antitrypsin Deficiency - diagnosis | Homozygote | Phenotype | Animals | Fatty Liver - diagnosis | alpha 1-Antitrypsin Deficiency - complications | Sex Factors | Aged | Mutation | Elasticity Imaging Techniques | Fatty Liver - etiology | Index Medicus | Abridged Index Medicus
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