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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 08/2016, Volume 17, Issue 8, pp. 1339 - 1339
Journal Article
DRUGS, ISSN 0012-6667, 2006, Volume 66, Issue 3, pp. 287 - 301
alpha(1)-Adrenoceptor antagonists such as alfuzosin, doxazosin, tamsulosin and terazosin are first-line agents for the treatment of lower urinary tract... 
BENIGN PROSTATIC HYPERPLASIA | URINARY-TRACT SYMPTOMS | HUMAN CORPUS CAVERNOSUM | BLADDER OUTLET OBSTRUCTION | SELECTIVE ALPHA(1A)-ADRENOCEPTOR ANTAGONIST | PHARMACOLOGY & PHARMACY | ALFUZOSIN 10 MG | TOXICOLOGY | QUALITY-OF-LIFE | SUSTAINED-RELEASE ALFUZOSIN | LONG-TERM EFFICACY | PHASE-III MULTICENTER
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 01/2002, Volume 62, Issue 2, pp. 597 - 602
Recent evidence suggests that the quinazoline-based at-adrenoceptor antagonists, doxazosin and terazosin, exhibit a potent apoptotic effect against prostate... 
BCL-2 | ACTIVATION | ONCOLOGY | PROLIFERATION | TERAZOSIN | DOXAZOSIN | HYPERPLASIA | EXPRESSION | SMOOTH-MUSCLE CELLS | ALPHA(1A)-ADRENOCEPTOR | ENDOTHELIAL GROWTH-FACTOR
Journal Article
HYPERTENSION RESEARCH, ISSN 0916-9636, 08/2019, Volume 42, Issue 8, pp. 1125 - 1141
We investigated the therapeutic effect of MH-76 and MH-79, which are non-quinazoline alpha 1-adrenoceptor antagonists with an additional ability to stimulate... 
alpha-adrenoceptor antagonist | SEROTONIN RECEPTOR | nitric oxide | MANAGEMENT | MECHANISM | DOCA-salt hypertensive rats | INVOLVEMENT | AROXYALKYL DERIVATIVES | endothelial dysfunction | BLOOD-PRESSURE | THERAPY | PERIPHERAL VASCULAR DISEASE | DOXAZOSIN | BLOCKER
Journal Article
JOURNAL OF UROLOGY, ISSN 0022-5347, 11/2007, Volume 178, Issue 5, pp. 2176 - 2180
Purpose: The quinazoline based alpha 1-adrenoceptor antagonists doxazosin and terazosin suppress prostate tumor growth via the induction of apoptosis and... 
APOPTOSIS | CELLS | FINASTERIDE | TERAZOSIN | INDUCTION | HYPERPLASIA | epidemiology | THERAPY | BENIGN | prostatic neoplasms | GROWTH | UROLOGY & NEPHROLOGY | prostate | adrenergic alpha-antagonists | quinazolines | DOXAZOSIN
Journal Article
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 08/2000, Volume 60, Issue 16, pp. 4550 - 4555
Recent evidence from our laboratory has demonstrated that alpha 1-adrenoceptor antagonists doxazosin and terazosin induced apoptosis in prostate epithelial and... 
MULTICENTER | MESSENGER-RNA | EFFICACY | ONCOLOGY | SUBTYPES | PROLIFERATION | ALPHA-ADRENERGIC RECEPTOR | HYPERPLASIA | HYPERTENSION | PROTEINS | SMOOTH-MUSCLE CELLS
Journal Article
Endocrine, ISSN 1355-008X, 10/2010, Volume 38, Issue 2, pp. 254 - 259
The objective of this article is to evaluate the efficacy of Doxazosin Mesylate Controlled Release Tablets for preoperative treatment of patients with... 
Pheochromocytoma | α-Adrenoceptor antagonist | Preoperative management | alpha-Adrenoceptor antagonist | DOXAZOSIN | ENDOCRINOLOGY & METABOLISM
Journal Article
Journal Article
CLINICAL AND EXPERIMENTAL MEDICINE, ISSN 1591-8890, 06/2010, Volume 10, Issue 2, pp. 99 - 106
alpha 1-Adrenoceptor antagonists (alpha 1-blockers) are currently used as first-line drugs for the treatment of benign prostatic hyperplasia (BPH). However,... 
MEDICINE, RESEARCH & EXPERIMENTAL | SMOOTH-MUSCLE | alpha 1-Adrenoceptor antagonist | Collagen fiber | EFFICACY | Morphometrical analysis | OBSTRUCTION | GROWTH | Benign prostatic hyperplasia | HYPERPLASIA | DOXAZOSIN | Prostatic tissue architecture
Journal Article
Drugs, ISSN 0012-6667, 2006, Volume 66, Issue 3, pp. 287 - 301
α1-Adrenoceptor antagonists such as alfuzosin, doxazosin, tamsulosin and terazosin are first-line agents for the treatment of lower urinary tract symptoms... 
Alpha 1 adrenoceptor antagonists | Benign prostatic hyperplasia | Sexual function
Journal Article
JOURNAL OF TRANSLATIONAL MEDICINE, ISSN 1479-5876, 07/2006, Volume 4
Background: It is well known that the use of the alpha-adrenergic receptor antagonists in the BPH therapy may induce ejaculatory disorder. A review of clinical... 
BENIGN PROSTATIC HYPERPLASIA | MEDICINE, RESEARCH & EXPERIMENTAL | VAS-DEFERENS | URINARY-TRACT SYMPTOMS | ALPHA-ADRENOCEPTOR ANTAGONISTS | TOLERABILITY | OBSTRUCTION | TAMSULOSIN | ALFUZOSIN | BLADDER NECK | EXPRESSION
Journal Article
ANTICANCER RESEARCH, ISSN 0250-7005, 05/2002, Volume 22, Issue 3, pp. 1673 - 1679
Background: Androgen-independent prostate cancer cells can undergo apoptosis in response to non-androgen ablative means such as ionizing radiation. Recent... 
apoptosis | TERAZOSIN | HYPERPLASIA | RADIATION-INDUCED APOPTOSIS | BCL-2 | prostate cancer | THERAPY | ONCOLOGY | radiation | GROWTH | alpha 1-adrenoceptor antagonists | RADIOTHERAPY | DOXAZOSIN | BRACHYTHERAPY | EXPRESSION
Journal Article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0223-5234, 10/2016, Volume 122, pp. 601 - 610
Arylpiperazines 2-11 were synthesized, and their biological profiles at alpha 1-adrenergic receptors (alpha 1-ARs) assessed by binding assays in CHO cells... 
ADRENOCEPTOR | DESIGN | CHEMISTRY, MEDICINAL | Adrenergic receptors subtypes | 5-HT1A RECEPTORS | alpha-Adrenergic antagonists | PHARMACOLOGICAL CHARACTERIZATION | CELL-GROWTH | DISCOVERY | Arylpiperazines | BENIGN PROSTATIC HYPERPLASIA | CONTRACTION | BIOLOGICAL EVALUATION | ALPHA-ADRENERGIC RECEPTORS | BPH
Journal Article
GENE THERAPY AND MOLECULAR BIOLOGY, ISSN 1529-9120, 2008, Volume 12B, pp. 253 - 257
Previous studies documented that human bladder cancer cells are sensitive to the apoptotic effects of quinazoline-derived alpha 1-adrenoreceptor antagonists... 
MIGRATION | MEDICINE, RESEARCH & EXPERIMENTAL | ANGIOGENESIS | alpha 1-adrenoceptor Antagonists | Bladder Cancer | TERAZOSIN | INDUCTION | Prevention | BENIGN PROSTATIC HYPERPLASIA | THERAPY | GROWTH | SMOOTH-MUSCLE-CELLS | DOXAZOSIN | Apoptosis
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 08/2000, Volume 14, Issue 11, pp. 1548 - 1558
Journal Article
PROSTATE, ISSN 0270-4137, 07/2001, Volume 48, Issue 2, pp. 71 - 78
BACKGROUND. We previously demonstrated that the quinazoline-derived a1-adrenoceptor antagonists doxazosin and terazosin suppress prostate cancer growth via... 
CANCER-CELLS | ANGIOGENESIS | microvessel density | apoptosis | CELL-PROLIFERATION | HYPERPLASIA | prostate cancer | BENIGN | ENDOCRINOLOGY & METABOLISM | UROLOGY & NEPHROLOGY | alpha 1-adrenoceptor antagonists | CARCINOMA | BCL-2 EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | ANTIGEN
Journal Article
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