Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (323) 323
alpha-l-fucosidase - metabolism (300) 300
biochemistry & molecular biology (275) 275
alpha-l-fucosidase (267) 267
animals (254) 254
index medicus (161) 161
kinetics (129) 129
female (117) 117
male (117) 117
chemistry, organic (111) 111
alpha-l-fucosidase - isolation & purification (103) 103
molecular sequence data (96) 96
hydrogen-ion concentration (95) 95
substrate specificity (95) 95
alpha-l-fucosidase - chemistry (89) 89
alpha-l-fucosidase - genetics (88) 88
liver - enzymology (71) 71
molecular weight (67) 67
glycoside hydrolases - metabolism (66) 66
alpha-l-fucosidase - antagonists & inhibitors (65) 65
alpha-l-fucosidase - blood (65) 65
lysosomes - enzymology (63) 63
carbohydrate sequence (62) 62
glycosylation (62) 62
purification (62) 62
fucose - metabolism (60) 60
enzymes (57) 57
derivatives (54) 54
adult (53) 53
oligosaccharides (49) 49
α-l-fucosidase (49) 49
enzyme inhibitors - pharmacology (47) 47
glycosidase inhibitors (46) 46
cattle (45) 45
rats (44) 44
amino acid sequence (43) 43
hydrolysis (43) 43
oligosaccharides - metabolism (43) 43
electrophoresis, polyacrylamide gel (42) 42
enzyme inhibitors - chemistry (42) 42
isoelectric focusing (42) 42
beta-galactosidase - metabolism (41) 41
chemistry, medicinal (41) 41
alpha-l-fucosidase - analysis (37) 37
chemistry, multidisciplinary (37) 37
enzyme inhibitors - chemical synthesis (37) 37
structure-activity relationship (37) 37
glycosidases (36) 36
carbohydrate conformation (35) 35
mice (35) 35
middle aged (35) 35
proteins (35) 35
identification (34) 34
cell biology (33) 33
mannosidases - metabolism (33) 33
molecular structure (33) 33
oligosaccharides - chemistry (33) 33
alpha -l-fucosidase (32) 32
alpha-l-fucosidases (32) 32
alpha-mannosidase (32) 32
cells, cultured (32) 32
base sequence (31) 31
biophysics (31) 31
fucosidase (31) 31
glycoproteins (31) 31
mutation (31) 31
research article (31) 31
stereoisomerism (31) 31
catalysis (30) 30
research (30) 30
chemistry, applied (29) 29
chromatography, affinity (28) 28
fucose (28) 28
polysaccharides - metabolism (28) 28
chemistry (27) 27
chromatography, gel (27) 27
alpha-l-fucosidase - deficiency (26) 26
analysis (26) 26
biotechnology & applied microbiology (26) 26
child (26) 26
glycoside hydrolases - antagonists & inhibitors (26) 26
inhibitors (26) 26
kidney - enzymology (26) 26
microbiology (26) 26
thermotoga-maritima (26) 26
cell line (25) 25
serum (25) 25
glycosidase (24) 24
isoenzymes - metabolism (24) 24
carbohydrates (23) 23
blotting, western (22) 22
fucose - chemistry (22) 22
l-fucose (22) 22
mannosidases - blood (22) 22
protein (22) 22
temperature (22) 22
fibroblasts - enzymology (21) 21
glycoproteins - metabolism (21) 21
liver (21) 21
acetylglucosaminidase - metabolism (20) 20
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (780) 780
Russian (5) 5
French (4) 4
German (2) 2
Czech (1) 1
Japanese (1) 1
Polish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Polymeric iminosugars improve the activity of carbohydrate-processing enzymes
by Brissonnet, Yoan and Ladevèze, Simon and Tezé, David and Fabre, Emeline and Deniaud, David and Daligault, Franck and Tellier, Charles and Šesták, Sergej and Remaud-Simeon, Magali and Potocki-Veronese, Gabrielle and Gouin, Sébastien G
Bioconjugate Chemistry, ISSN 1043-1802, 04/2015, Volume 26, Issue 4, pp. 766 - 772
Multivalent iminosugars have recently emerged as powerful tools to inhibit the activities of specific glycosidases. In this work, biocompatible dextrans were... 
CLICK CLUSTERS | GLYCOSIDASE INHIBITION | BALLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEXTRAN | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | MULTIVALENT | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | Phosphorylases - chemistry | alpha-L-Fucosidase - chemistry | Coated Materials, Biocompatible - chemistry | Glycoside Hydrolases - chemistry | Polymerization | Dextrans - chemistry | Ligands | Enzyme Activation | Imino Sugars - chemistry | Phosphoric Diester Hydrolases - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text A common glycan structure on immunoglobulin G for enhancement of effector functions
by Chin-Wei Lin and Ming-Hung Tsai and Shiou-Ting Li and Tsung-I Tsai and Kuo-Ching Chu and Ying-Chih Liu and Meng-Yu Lai and Chia-Yu Wu and Yung-Chieh Tseng and Sachin S. Shivatare and Chia-Hung Wang and Ping Chao and Shi-Yun Wang and Hao-Wei Shih and Yi-Fang Zeng and Tsai-Hong You and Jung-Yu Liao and Yu-Chen Tu and Yih-Shyan Lin and Hong-Yang Chuang and Chia-Lin Chen and Charng-Sheng Tsai and Chiu-Chen Huang and Nan-Horng Lin and Che Ma and Chung-Yi Wu and Chi-Huey Wong
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2015, Volume 112, Issue 34, pp. 10611 - 10616
Antibodies have been developed as therapeutic agents for the treatment of cancer, infection, and inflammation. In addition to binding activity toward the... 
Fc glycosylation | Endoglycosidase | Glycoengineered antibodies | Sugar oxazoline | Homogeneous antibodies | RHEUMATOID-ARTHRITIS | N-ACETYLGLUCOSAMINE | ANTIINFLAMMATORY ACTIVITY | FC-GAMMA-RIII | MULTIDISCIPLINARY SCIENCES | GLYCOFORMS | ANTIBODY | FUCOSE | DEPENDENT CELLULAR CYTOTOXICITY | STAUDINGER LIGATION | glycoengineered antibodies | endoglycosidase | sugar oxazoline | CHEMICAL LIGATION | homogeneous antibodies | Orthomyxoviridae Infections - prevention & control | Acetylglucosamine - immunology | Humans | Structure-Activity Relationship | Sialic Acids - chemistry | Immunoglobulin Fc Fragments - immunology | Immunoglobulin G - immunology | HEK293 Cells | Protein Engineering | Polysaccharides - chemistry | Female | Rituximab - chemistry | Sialic Acids - immunology | Trastuzumab - chemistry | Antibodies, Viral - therapeutic use | Antibody-Dependent Cell Cytotoxicity | alpha-L-Fucosidase - metabolism | Immunoglobulin G - chemistry | Neuraminidase - metabolism | Immunoglobulin Fc Fragments - chemistry | Bacteroides fragilis - enzymology | Receptors, IgG - immunology | Acetylglucosamine - chemistry | Animals | Streptococcus pyogenes - enzymology | Antibodies, Viral - chemistry | Lymphoma, B-Cell - pathology | Cell Line, Tumor | Antibodies, Viral - immunology | Bacterial Proteins - metabolism | Mice | Mice, Inbred BALB C | Rituximab - immunology | Trastuzumab - immunology | Viral antibodies | Medical research | Tissue engineering | Immunoglobulin G | Antibodies | Medicine, Experimental | Genetic aspects | Research | Properties | Immune system | Biological Sciences | Physical Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text The fucosidase-pool of Emticicia oligotrophica: Biochemical characterization and transfucosylation potential
by Liu, Si and Kulinich, Anna and Cai, Zhi P and Ma, Hong Y and Du, Ya M and Lv, Yong M and Liu, Li and Voglmeir, Josef
Glycobiology, ISSN 0959-6658, 08/2016, Volume 26, Issue 8, pp. 871 - 879
Three novel bacterial alpha-L-fucosidases, which cleave terminal fucosyl residues from glycoconjugates are reported in this work. Originating from the recently... 
transfucosylation | fucosidase | bacterial glycosidases | fucose-containing oligosaccharide | Emticicia oligotrophica | PROTEIN | SPECIFICITY | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA-L-FUCOSIDASE | IDENTIFICATION | ENZYME | PURIFICATION | THERMOTOGA-MARITIMA | MILK OLIGOSACCHARIDES | TRANSGLYCOSYLATION | alpha-L-Fucosidase - genetics | Fucose - chemistry | Temperature | Stereoisomerism | Fucose - metabolism | Bacterial Proteins - chemistry | Substrate Specificity | Isoenzymes - chemistry | Zinc - chemistry | Bacteroidetes - enzymology | Calcium - chemistry | Isoenzymes - metabolism | Cloning, Molecular | Escherichia coli - metabolism | Hymecromone - chemistry | Recombinant Proteins - metabolism | Gene Expression | Biocatalysis | Genetic Vectors - chemistry | Isoenzymes - genetics | alpha-L-Fucosidase - metabolism | Bacterial Proteins - genetics | Bacteroidetes - chemistry | Genetic Vectors - metabolism | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Manganese - chemistry | Hydrolysis | Cations, Divalent | Escherichia coli - genetics | alpha-L-Fucosidase - chemistry | Bacterial Proteins - metabolism | Kinetics | Hydrogen-Ion Concentration
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Biological Properties of d- and l-1-Deoxyazasugars
by Kato, Atsushi and Kato, Noriko and Kano, Erika and Adachi, Isao and Ikeda, Kyoko and Yu, Liang and Okamoto, Tadashi and Banba, Yasunori and Ouchi, Hidekazu and Takahata, Hiroki and Asano, Naoki
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2005, Volume 48, Issue 6, pp. 2036 - 2044
l-Enantiomers of 1-deoxynojirimycin (DNJ), 1-deoxymannojirimycin (manno-DNJ), 1-deoxyallonojirimycin (allo-DNJ), 1-deoxyaltronojirimycin (altro-DNJ),... 
POLYHYDROXYLATED ALKALOIDS | THERAPEUTIC APPLICATIONS | CHEMISTRY, MEDICINAL | ANGYLOCALYX-PYNAERTII | D-ERYTHRO-SPHINGOSINE | D-THREO-SPHINGOSINE | CHIRAL BUILDING-BLOCK | ENDOPLASMIC-RETICULUM | ALPHA-L-FUCOSIDASE | LYSOSOMAL STORAGE DISORDERS | GLYCOSIDASE INHIBITORS | Species Specificity | alpha-Galactosidase - antagonists & inhibitors | Stereoisomerism | Humans | alpha-Mannosidase - chemistry | alpha-Mannosidase - antagonists & inhibitors | 1-Deoxynojirimycin - chemistry | Lysosomes - enzymology | Male | 1-Deoxynojirimycin - chemical synthesis | Structure-Activity Relationship | Enzyme Inhibitors - chemical synthesis | beta-Glucosidase - chemistry | alpha-Galactosidase - chemistry | Molecular Mimicry | beta-Glucosidase - antagonists & inhibitors | Cattle | Enzyme Inhibitors - chemistry | beta-Galactosidase - chemistry | beta-Mannosidase - chemistry | Glucan 1,4-alpha-Glucosidase - antagonists & inhibitors | alpha-L-Fucosidase - antagonists & inhibitors | beta-Mannosidase - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | beta-Galactosidase - antagonists & inhibitors | Rats | 1-Deoxynojirimycin - pharmacology | Animals | Glucan 1,4-alpha-Glucosidase - chemistry | alpha-L-Fucosidase - chemistry | In Vitro Techniques
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Application study of 1,2-α-l-fucosynthase: introduction of Fucα1-2Gal disaccharide structures on N-glycan, ganglioside, and xyloglucan oligosaccharide
by Sugiyama, Yuta and Katoh, Toshihiko and Honda, Yuji and Gotoh, Aina and Ashida, Hisashi and Kurihara, Shin and Yamamoto, Kenji and Katayama, Takane
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 02/2017, Volume 81, Issue 2, pp. 283 - 291
We have recently generated a highly efficient 1,2-α-l-fucosynthase (BbAfcA N423H mutant) by protein engineering of 1,2-α-l-fucosidase from Bifidobacterium... 
H-antigen | glycosynthase | oligosaccharide | sugar chains | 1,2-α-l-fucosidase | Sugar chains | 1,2-α-L-fucosidase | Glycosynthase | Hantigen | Oligosaccharide | alpha-L-Fucosidase - genetics | Fucose - chemistry | Xylans - metabolism | Disaccharides - metabolism | alpha-L-Fucosidase - metabolism | Fucose - metabolism | Oligosaccharides - metabolism | Asialoglycoproteins - metabolism | Disaccharides - chemistry | Glycolipids - metabolism | Xylans - chemistry | Fetuins - metabolism | Gangliosides - metabolism | Oligosaccharides - chemistry | Protein Engineering | Glycolipids - chemistry | Bifidobacterium - enzymology | Glucans - chemistry | Glucans - metabolism | Mutation | Plants - chemistry | Gangliosides - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Glycomimetics at the mirror: Medicinal chemistry of L-iminosugars
by D'Alonzo, Daniele and Guaragna, Annalisa and Palumbo, Giovanni
Current Medicinal Chemistry, ISSN 0929-8673, 2009, Volume 16, Issue 4, pp. 473 - 505
Inhibition of carbohydrate processing enzymes is a topic of great interest, as these enzymes are involved in a plethora of key biochemical events, such as... 
Glycosidase inhibitors | Mirror-image inhibitors | Glycomimetics | Iminosugars | Carbohydrate-processing enzymes | Noncompetitive inhibitors | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOOKING-GLASS INHIBITORS | D-MANNOSIDASE | carbohydrate-processing enzymes | L-RHAMNOSIDASE | mirror-image inhibitors | ALPHA-L-FUCOSIDASE | HUMAN ALPHA-1,3-FUCOSYL-TRANSFERASE V | LYSOSOMAL STORAGE DISORDERS | GLYCOSYLTRANSFERASE INHIBITORS | glycosidase inhibitors | GAUCHER-DISEASE | glycomimetics | noncompetitive inhibitors | HEPATITIS-C VIRUS | PHARMACOLOGY & PHARMACY | Stereoisomerism | Humans | Imino Sugars - pharmacology | Enzyme Inhibitors - pharmacology | Structure-Activity Relationship | Imino Sugars - metabolism | Chemistry, Pharmaceutical | Animals | Enzyme Inhibitors - chemistry | Glycoside Hydrolases - chemistry | Molecular Structure | Glycoside Hydrolases - metabolism | Glycoside Hydrolases - antagonists & inhibitors | Imino Sugars - chemistry
Journal Article
Details down arrow
7. Full Text Biological activities of 3,4,5‐trihydroxypiperidines and their N‐ and O‐derivatives
by Prichard, Kate and Campkin, David and O'Brien, Nicholas and Kato, Atsushi and Fleet, George W. J and Simone, Michela I
Chemical Biology & Drug Design, ISSN 1747-0277, 07/2018, Volume 92, Issue 1, pp. 1171 - 1197
3,4,5‐Trihydroxypiperidines belong to the family of 1,5‐dideoxy‐1,5‐iminosugar natural products and are structural analogues of pentose monosaccharides in the... 
iminosugar | anti‐diabetes | glycosidase | anti‐bacterial | immunosuppressant | piperidine | lysosomal disease | anti-bacterial | anti-diabetes | CHEMISTRY, MEDICINAL | PHARMACOLOGICAL CHAPERONES | BIOCHEMISTRY & MOLECULAR BIOLOGY | IMMUNOSUPPRESSIVE AGENTS | IMINOSUGARS | LYSOSOMAL STORAGE DISORDERS | ALPHA-L-FUCOSIDASE | GLYCOSIDASE INHIBITORS | GAUCHER-DISEASE | MIT STICKSTOFFHALTIGEM RING | SELECTIVE INHIBITORS | ACID BETA-GLUCOSIDASE | Antiviral Agents - pharmacology | Piperidines - chemistry | Enzyme Inhibitors - metabolism | HIV-1 - drug effects | Graft Rejection - prevention & control | 1-Deoxynojirimycin - chemistry | Biological Products - pharmacology | Biological Products - chemistry | Animals | Piperidines - pharmacology | Antiviral Agents - chemistry | Piperidines - therapeutic use | Enzyme Inhibitors - chemistry | Glycoside Hydrolases - metabolism | Monosaccharides - chemistry | Glycoside Hydrolases - antagonists & inhibitors | Biological Products - therapeutic use | Sugars | Immunosuppressive agents | Monosaccharides
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Novel Spectrofluorimetric Method for Measuring the Activity of the Enzyme α-l-Fucosidase Using the Nano Composite Optical Sensor Samarium(III)−Doxycycline Complex Doped in Sol−Gel Matrix
by Attia, M. S and Othman, A. M and Aboaly, M. M and Abdel-Mottaleb, M. S. A
Analytical Chemistry, ISSN 0003-2700, 07/2010, Volume 82, Issue 14, pp. 6230 - 6236
A novel, simple, sensitive, and precise spectrofluorimetric method was developed for measuring the activity of the enzyme α-l-fucosidase (AFU). The method was... 
CHEMISTRY, ANALYTICAL | HEPATOCELLULAR-CARCINOMA | ASSAY | GENE | IDENTIFICATION | Fluorescent Dyes - chemistry | Spectrometry, Fluorescence - methods | Nanocomposites - chemistry | Doxycycline - chemistry | alpha-L-Fucosidase - metabolism | Humans | Middle Aged | Enzyme Assays - methods | Male | Nitrophenols - chemistry | Samarium - chemistry | Adult | Female | Aged | Gels - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text α‐L‐Fucosidase Inhibition by Pyrrolidine–Ferrocene Hybrids: Rationalization of Ligand‐Binding Properties by Structural Studies
by Hottin, Audrey and Wright, Daniel W and Steenackers, Agata and Delannoy, Philippe and Dubar, Faustine and Biot, Christophe and Davies, Gideon J and Behr, Jean‐Bernard
Chemistry – A European Journal, ISSN 0947-6539, 07/2013, Volume 19, Issue 29, pp. 9526 - 9533
Enhanced metabolism of fucose through fucosidase overexpression is a signature of some cancer types, thus suggesting that fucosidase‐targetted ligands could... 
hydrolases | protein structures | inhibition | glycosidases | antitumor agents | alpha-L-Fucosidase - antagonists & inhibitors | Cell Proliferation | alpha-L-Fucosidase - metabolism | Humans | Molecular Conformation | Antineoplastic Agents - chemistry | Pyrrolidines - chemistry | Drug Delivery Systems | Animals | Cattle | Enzyme Inhibitors - chemistry | alpha-L-Fucosidase - chemistry | Glycoside Hydrolases - chemistry | Ferrous Compounds - chemistry | Hydrolases - chemistry | Molecular Structure | Metallocenes | Enzyme Inhibitors | Biochemistry, Molecular Biology | Antineoplastic Agents | alpha-L-Fucosidase | Life Sciences | Ferrous Compounds | Glycoside Hydrolases | Pyrrolidines | Hydrolases
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Design of an α-l-transfucosidase for the synthesis of fucosylated HMOs
by Saumonneau, Amélie and Champion, Elise and Peltier-Pain, Pauline and Molnar-Gabor, Dora and Hendrickx, Johann and Tran, Vinh and Hederos, Markus and Dekany, Gyula and Tellier, Charles
Glycobiology, ISSN 0959-6658, 09/2015, Volume 26, Issue 3, pp. 261 - 269
Human milk oligosaccharides (HMOs) are recognized as benefiting breast-fed infants in multiple ways. As a result, there is growing interest in the synthesis of... 
transfucosylation | human milk oligosaccharides | enzymatic synthesis | fucosidase | Bifidobacterium longum subsp. infantis | L-FUCOSIDASE | Bifidobacterium longum subsp | GLYCOSIDASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 1,2-ALPHA-L-FUCOSIDASE | BIFIDOBACTERIUM-BIFIDUM | SEMI-RATIONAL APPROACH | infantis | INHIBITION | STRUCTURAL BASIS | HUMAN-MILK OLIGOSACCHARIDES | THERMOTOGA-MARITIMA | alpha-L-Fucosidase - genetics | Fucose - chemistry | Humans | Substrate Specificity | Infant | Glycosylation | Milk, Human - chemistry | Mutation - genetics | Oligosaccharides - chemical synthesis | Oligosaccharides - chemistry | alpha-L-Fucosidase - chemistry | Polysaccharides - chemistry | Bifidobacterium - enzymology | Amino Sugars - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Designer α1,6-Fucosidase Mutants Enable Direct Core Fucosylation of Intact N‑Glycopeptides and N‑Glycoproteins
by Li, Chao and Zhu, Shilei and Ma, Christopher and Wang, Lai-Xi
Journal of the American Chemical Society, ISSN 0002-7863, 10/2017, Volume 139, Issue 42, pp. 15074 - 15087
Core fucosylation of N-glycoproteins plays a crucial role in modulating the biological functions of glycoproteins. Yet, the synthesis of structurally... 
alpha-L-Fucosidase - genetics | Lactobacillus casei - enzymology | Antibodies - metabolism | alpha-L-Fucosidase - metabolism | Antibodies - chemistry | Fucose - metabolism | Glycoproteins - metabolism | Mutant Proteins - genetics | Glycopeptides - chemistry | Substrate Specificity | Mutant Proteins - metabolism | Glycosylation | Glycopeptides - metabolism | Mutant Proteins - chemistry | alpha-L-Fucosidase - chemistry | Mutation | Glycoproteins - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Candida albicans impairments induced by peppermint and clove oils at sub-inhibitory concentrations
by Rajkowska, Katarzyna and Otlewska, Anna and Kunicka-Styczyńska, Alina and Krajewska, Agnieszka
International Journal of Molecular Sciences, ISSN 1661-6596, 06/2017, Volume 18, Issue 6, p. 1307
Members of Candida species cause significant health problems, inducing various types of superficial and deep-seated mycoses in humans. In order to prevent from... 
Candida albicans | Proteins profile | Anticandidal activity | Enzymatic activity | Essential oils | Karyotype | GLABRATA | BIOCHEMISTRY & MOLECULAR BIOLOGY | TEA TREE | ANTIBACTERIAL | proteins profile | MECHANISMS | SACCHAROMYCES-CEREVISIAE | CHEMISTRY, MULTIDISCIPLINARY | karyotype | enzymatic activity | anticandidal activity | essential oils | PROTEINS | Antifungal Agents - pharmacology | Hexosaminidases - drug effects | Plant Extracts - chemistry | Plant Oils - pharmacology | Molecular Weight | Clove Oil - chemistry | Plant Extracts - pharmacology | Humans | Fungal Proteins - drug effects | Antifungal Agents - chemistry | Enzyme Assays | Oils, Volatile | Candida albicans - metabolism | Candida albicans - growth & development | Clove Oil - pharmacology | Mentha piperita - chemistry | Microbial Sensitivity Tests | Candida albicans - drug effects | alpha-L-Fucosidase - drug effects | Plant Oils - chemistry | Candida albicans - enzymology | Chromosomes, Fungal - drug effects | Fungal Proteins - metabolism | Enzymes | Yeast | Fungicides | Toxicity | Peppermint | Cell division | Antimicrobial agents | Metabolism | Chromosome rearrangements | Pathogenicity | Proteins | Antifungal activity | Alterations | Numerical analysis | Morphology | Minimum inhibitory concentration | Oils & fats | Mutation | Respiration | Deoxyribonucleic acid--DNA | Food | Glucosaminidase
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Rice α-fucosidase active against plant complex type N-glycans containing Lewis a epitope: purification and characterization
by Rahman, Md. Ziaur and Fujishige, Makoto and Maeda, Megumi and Kimura, Yoshinobu
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 02/2016, Volume 80, Issue 2, pp. 291 - 294
Rice α-fucosidase (α-fucosidase Os, 58 kDa) that is active for α1-4 fucosyl linkage in Lewis a unit of plant N-glycans was purified to homogeneity.... 
α-fucosidase | N-glycan degradation | Oryza sativa | plant N-glycan | Plant N-glycan | OLIGOSACCHARIDES | SPECIFICITIES | fucosidase | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | AFFINITY-CHROMATOGRAPHY | CHEMISTRY, APPLIED | ALMOND EMULSIN | alpha-L-Fucosidase - genetics | Epitopes - metabolism | Molecular Weight | Molecular Sequence Data | Substrate Specificity | Phylogeny | Oryza - classification | alpha-L-Fucosidase - isolation & purification | Oryza - genetics | Plant Proteins - chemistry | Oligosaccharides - chemistry | Polysaccharides - chemistry | Plant Proteins - metabolism | Carbohydrate Sequence | Plant Proteins - isolation & purification | Amino Acid Sequence | Gene Expression | alpha-L-Fucosidase - metabolism | Oligosaccharides - metabolism | Oryza - enzymology | Polysaccharides - metabolism | Plant Proteins - genetics | Amino Sugars - metabolism | alpha-L-Fucosidase - chemistry | Epitopes - chemistry | Amino Sugars - chemistry | Kinetics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text 1,3-1,4-α-L-Fucosynthase that specifically introduces Lewis a/x antigens into type-1/2 chains
by Sakurama, Haruko and Fushinobu, Shinya and Hidaka, Masafumi and Yoshida, Erina and Honda, Yuji and Ashida, Hisashi and Kitaoka, Motomitsu and Kumagai, Hidehiko and Yamamoto, Kenji and Katayama, Takane
Journal of Biological Chemistry, ISSN 0021-9258, 05/2012, Volume 287, Issue 20, pp. 16709 - 16719
alpha-L-Fucosyl residues attached at the non-reducing ends of glycoconjugates constitute histo-blood group antigens Lewis (Le) and ABO and play fundamental... 
BIFIDOBACTERIUM-LONGUM | ENGINEERED ESCHERICHIA-COLI | REACTION-MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | CATALYTIC NUCLEOPHILE | ENZYMATIC-SYNTHESIS | PENICILLIUM-MULTICOLOR | ALPHA-L-FUCOSIDASE | HUMAN-MILK OLIGOSACCHARIDES | THERMOTOGA-MARITIMA | GLYCOSIDE HYDROLASE | Fucose - chemistry | Fucosyltransferases - genetics | Catalytic Domain | Fucosyltransferases - chemistry | Bifidobacterium - genetics | Humans | Oligosaccharides - chemistry | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Bifidobacterium - enzymology | Epitopes - chemistry | Enzyme Mechanisms | Glycobiology and Extracellular Matrices | Glycobiology | X-ray Crystallography | Carbohydrate Glycoconjugate | Oligosaccharide
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Exploiting the Hydrophobic Terrain in Fucosidases with Aryl‐Substituted Pyrrolidine Iminosugars
by Hottin, Audrey and Wright, Daniel W and Davies, Gideon J and Behr, Jean‐Bernard
ChemBioChem, ISSN 1439-4227, 01/2015, Volume 16, Issue 2, pp. 277 - 283
Fucosidase inhibition shows potential in numerous therapeutic contexts. Substitution of fucose‐like iminosugars with hydrophobic “aglycons” yields significant... 
inhibition | fucosidases | hydrophobic interactions | azasugars | structure | Fucosidases | Hydrophobic interactions | Inhibition | Structure | Azasugars | CHEMISTRY, MEDICINAL | SERIES | CANCER CELLS | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA-L-FUCOSIDASE | INHIBITORS | BINDING | INSIGHTS | DIYNES | alpha-L-Fucosidase - antagonists & inhibitors | Chemistry Techniques, Synthetic | Enzyme Inhibitors - metabolism | alpha-L-Fucosidase - metabolism | Imino Sugars - pharmacology | Kidney - enzymology | Enzyme Inhibitors - pharmacology | Crystallography, X-Ray | Structure-Activity Relationship | Pyrrolidines - chemistry | Animals | Cattle | Enzyme Inhibitors - chemistry | alpha-L-Fucosidase - chemistry | Hydrophobic and Hydrophilic Interactions | Protein Conformation | Imino Sugars - chemistry | Alkaloids | Triazoles | Resveratrol | Enzymes
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text Development of Activity-Based Probes for Imaging Human α- L -Fucosidases in Cells
by Hsu, Yu-Ling and Nandakumar, Manjula and Lai, Hsin-Yi and Chou, Tzyy-Chao and Chu, Chi-Yuan and Lin, Chun-Hung and Lo, Lee-Chiang
Journal of Organic Chemistry, ISSN 0022-3263, 08/2015, Volume 80, Issue 16, pp. 8458 - 8463
We have established a concise synthetic route relying on a key base-promoted epimerization step to synthesize two series of activity-based probes carrying a... 
DESIGN | GLYCOSIDASES | OLIGOSACCHARIDES | ENZYME-ACTIVITY | MECHANISM | PROTEIN-TYROSINE PHOSPHATASES | CHEMISTRY, ORGANIC | INHIBITORS | GLYCOSYLATION | STEROID SULFATASE | DISCOVERY | Boron Compounds - chemistry | Cell Membrane - chemistry | Cell Membrane - enzymology | Humans | alpha-L-Fucosidase - chemistry | Fluorescence | Phenols - chemistry | Kinetics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
17. Full Text The spirocyclopropyl moiety as a methyl surrogate in the structure of l-fucosidase and l-rhamnosidase inhibitors
by Pearson, Morwenna S.M and Floquet, Nicolas and Bello, Claudia and Vogel, Pierre and Plantier-Royon, Richard and Szymoniak, Jan and Bertus, Philippe and Behr, Jean-Bernard
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2009, Volume 17, Issue 23, pp. 8020 - 8026
Nitrogen-in-the-ring analogues of -fucose and -rhamnose, which feature a spirocyclopropyl moiety in place of the methyl group of the natural sugar, were... 
Iminosugars | Inhibition | Glycosidases | Spiro compounds | CHEMISTRY, MEDICINAL | CHITIN SYNTHASE | SERIES | D-RIBOSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEDIATED SYNTHESIS | CHEMISTRY, ORGANIC | ALPHA-L-FUCOSIDASE | GLYCOSIDASE INHIBITORS | GLYCOSYLTRANSFERASE INHIBITORS | PRIMARY CYCLOPROPYLAMINES | COLORECTAL-CANCER | POLYHYDROXYLATED PYRROLIDINE | Rhamnose - chemistry | Fucose - chemistry | Fucose - analogs & derivatives | Rhamnose - analogs & derivatives | Rhamnose - chemical synthesis | Enzyme Inhibitors - chemical synthesis | Cyclopropanes - chemistry | Cyclopropanes - chemical synthesis | Spectrometry, Mass, Electrospray Ionization | Enzyme Inhibitors - chemistry | Spiro Compounds - chemical synthesis | Fucose - pharmacology | Fucose - chemical synthesis | Glycoside Hydrolases - antagonists & inhibitors | Spiro Compounds - chemistry | Cyclopropanes - pharmacology | alpha-L-Fucosidase - antagonists & inhibitors | Magnetic Resonance Spectroscopy | alpha-L-Fucosidase - metabolism | Rhamnose - pharmacology | Enzyme Inhibitors - pharmacology | Optical Rotation | Glycoside Hydrolases - metabolism | Kinetics | Spiro Compounds - pharmacology | Organic chemistry | Chemical Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
18. Full Text Synthesis of fluorescent Ag nanoclusters and their application in α-l-fucosidase detection
by Ren, Xiangling and Chen, Zhenzhen and Meng, Xianwei and Chen, Dong and Tang, Fangqiong
Chemical Communications, ISSN 1359-7345, 10/2012, Volume 48, Issue 76, pp. 9504 - 9506
Highly fluorescent Ag nanoclusters (NCs) were successfully prepared by a simple and nontoxic approach, and the as-prepared Ag NCs could be utilized for the AFu... 
GOLD NANOPARTICLES | SILVER NANOCLUSTERS | SENSOR | IONS | FACILE PREPARATION | CHEMISTRY, MULTIDISCIPLINARY | QUANTUM DOTS | Fluorescent Dyes - chemistry | Polymethacrylic Acids - chemistry | alpha-L-Fucosidase - analysis | Spectrophotometry, Ultraviolet | Metal Nanoparticles - chemistry | Silver - chemistry | Silver | Nanomaterials | Nanostructure | Synthesis | Nanocomposites
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights