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Chemical Society reviews, ISSN 0306-0012, 10/2017, Volume 46, Issue 19, pp. 5889 - 5902
Chiral Brønsted acids have found widespread applications as organocatalysts. Weakly acidic species such as diols and (thio)ureas, typically classified as... 
Journal Article
Chemical Society Reviews, ISSN 0306-0012, 10/2017, Volume 46, Issue 19, pp. 5889 - 592
Chiral Brønsted acids have found widespread applications as organocatalysts. Weakly acidic species such as diols and (thio)ureas, typically classified as... 
AZA-HENRY REACTION | C,N-CYCLIC AZOMETHINE IMINES | DICARBOXYLIC-ACID | N-BOC-IMINES | MANNICH-TYPE REACTION | BOND DONOR CATALYSTS | LEWIS-ACID | DIELS-ALDER REACTION | ALPHA-AMINO-ACIDS | PICTET-SPENGLER REACTIONS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 08/2018, Volume 140, Issue 32, pp. 10363 - 10367
An acetyl-protected aminoethyl phenyl thioether has been developed to promote C­(sp3)–H activation. Significant ligand enhancement is demonstrated by the... 
ROOM-TEMPERATURE | ALIPHATIC-ACIDS | MILD CONDITIONS | ARYLATION | ALPHA-AMINO-ACIDS | REDOX-ACTIVE ESTERS | STEREOSELECTIVE-SYNTHESIS | HECK REACTION | CHEMISTRY, MULTIDISCIPLINARY | C-H BONDS | UNACTIVATED ALKYL-HALIDES
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/2007, Volume 129, Issue 12, pp. 3466 - 3467
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 12/2015, Volume 54, Issue 52, pp. 15632 - 15641
Visible‐light‐induced radical decarboxylative functionalization of carboxylic acids and their derivatives has recently received considerable attention as a... 
radicals | photochemistry | synthetic methods | carboxylic acids | CC coupling | C-C coupling | ROOM-TEMPERATURE | OXIDATIVE DECARBOXYLATION | MERGING PHOTOREDOX | NICKEL CATALYSIS | SYNTHETIC APPLICATIONS | ALPHA-AMINO-ACIDS | BOND FORMATION | QUATERNARY CARBONS | C-H FUNCTIONALIZATION | CHEMISTRY, MULTIDISCIPLINARY | PHOTOREDOX CATALYSIS | Organic acids | Catalysis | Acids
Journal Article
Synthesis, ISSN 0039-7881, 10/2019, Volume 51, Issue 19, pp. 3683 - 3696
Abstract Acetaminophen is a popular antipyretic analgesic medicine that has weaker anti-inflammatory properties and lower incidence of side effects than... 
paper | DIPEPTIDES | CONVENIENT PEPTIDE-SYNTHESIS | acetaminophen | ACTIVATION | hepatotoxicity | alpha-amino acid | fatty acid | CHEMISTRY, ORGANIC | TOXICITY | AM404
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 09/2018, Volume 83, Issue 17, pp. 10564 - 10572
Asymmetric Michael reaction of iminoglycinate 4 to α,β-unsaturated esters had been developed with >98:<2 diastereoselectivity. A reverse of... 
GLUTAMIC ACIDS | ESTER | GLYCINE | ALLOKAINIC ACID | ENANTIOSELECTIVE SYNTHESIS | HUNTINGTONS-CHOREA | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | ASYMMETRIC MICHAEL ADDITION | KAINIC ACID | (+/-)-ALPHA-ALLOKAINIC ACID
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 04/2015, Volume 2015, Issue 10, pp. 2262 - 2270
4‐Amino(methyl)‐1,3‐thiazole‐5‐carboxylic acids (ATCs) are a new class of constrained heterocyclic γ‐amino acids built around a thiazole ring; these compounds... 
Heterocycles | Amino acids | Cross‐Claisen reactions | Peptidomimetics | Cross-Claisen reactions | ALPHA-AMINO | DESIGN | MIMETICS | BUILDING-BLOCKS | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | BETA-KETO-ESTERS | HYDROGEN-BONDED CONFORMATIONS | SCAFFOLDS | MODEL PEPTIDES | HYBRID PEPTIDES
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 05/2006, Volume 128, Issue 18, pp. 6048 - 6049
We describe the first efficient, direct asymmetric Mannich reactions with malonates and N-Boc aryl and alkyl imines by cooperative hydrogen-bonding catalysis... 
ALPHA-AMINO | ORGANOCATALYSTS | KETO-ESTERS | ASYMMETRIC STRECKER REACTION | CHIRAL BRONSTED ACID | ARYL | DERIVATIVES | QUATERNARY | CHEMISTRY, MULTIDISCIPLINARY | CONJUGATE ADDITION | MICHAEL ADDITION | Amino Acids - chemical synthesis | Catalysis | Malonates - chemistry | Stereoisomerism | Cinchona Alkaloids - chemistry | Imines - chemistry
Journal Article
Synthesis, ISSN 0039-7881, 02/2016, Volume 48, Issue 8, pp. 1122 - 1130
We describe the hitherto unknown use of N-Boc-protected hydrazine in the Ugi tetrazole reaction to access a library of highly substituted... 
tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 3 methylbutyl]hydrazine 1 carboxylic acid | tert butyl 2 [2 methyl 1 (1 phenethyl 1h tetrazol 5 yl)propyl]hydrazine 1 carboxylic acid | unclassified drug | proton transport | Ugi reaction | Ugi tetrazole reaction | tert butyl 2[1 (1 tert butyl 1h tetrazol 5 yl) 3 phenylpropyl]hydrazine 1 carboxylic acid | hydrazine | drug isolation | electrospray mass spectrometry | isocyanides | benzyl 4 [2 (tert butoxycarbonyl)hydrazino] 4[1 [2 (1h indol 3 yl)ethyl] 1h tetrazol 5 yl]piperidine 1 carboxylic acid | deprotection reaction | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 3 phenylpropyl]hydrazine 1 carboxylic acid | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 2 phenylethyl]hydrazine 1 carboxylic acid | tert butyl 2 [2 [1 (1 methoxy 4 methyl 1 oxopentan 2 yl) 1h tetrazol 5 yl]propan 2 yl]hydrazine 1 carboxylic acid | mass spectrometry | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 2 methylpropyl]hydrazine 1 carboxylic acid | tert butyl 2 [cyclohexyl(1 cyclohexyl 1h tetrazol 5 yl)methyl]hydrazine 1 carboxylic acid | proton nuclear magnetic resonance | hydrazine derivative | drug screening | chemical reaction | supercritical fluid chromatography | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl)(cyclohexyl)methyl]hydrazine 1 carboxylic acid | tert butyl 2 [1 (1 phenethyl 1h tetrazol 5 yl)cyclohexyl]hydrazine 1 carboxylic acid | article | carbon nuclear magnetic resonance | To be checked by Faculty | tert butyl 2 [3 methyl 1 (1 phenethyl 1h tetrazol 5 yl)butyl]hydrazine 1 carboxylic acid | one pot synthesis | tetrazoles | tert butyl 2 [1 chloro 2 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]propan 2 yl]hydrazine 1 carboxylic acid | tert butyl 2 [2 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]butan 2 yl]hydrazine 1 carboxylic acid | tert butyl 2 [1 [1 benzyl 4 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]piperidin 4 yl]]hydrazine 1 carboxylic acid | tert butyl 2 [cyclohexyl (1 phenethyl 1h tetrazol 5 yl)methyl]hydrazine 1 carboxylic acid | multicomponent reaction | tert butyl 2 [2 chloro 1 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]ethyl]hydrazine 1 carboxylic acid | paper | 3-COMPONENT REACTION | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | MULTICOMPONENT REACTIONS | DIASTEREOSELECTIVE SYNTHESIS | CHEMISTRY | DIVERSITY | LEWIS-ACIDS | 4-COMPONENT CONDENSATION | EFFICIENT
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2015, Volume 54, Issue 38, pp. 11196 - 11199
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 07/2016, Volume 2016, Issue 20, pp. 3331 - 3334
Aminodecarboxylation of unactivated alkanecarboxylic acids has been accomplished utilizing an organic photocatalyst. This operationally simple reaction... 
Carboxylic acids | Amination | Homogeneous catalysis | Photocatalysis | 9-MESITYL-10-METHYLACRIDINIUM ION | ALLYLATION | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | HYDRAZINES | ESTERS | LIGHT PHOTOREDOX CATALYSIS | OLEFINS | RADICALS | DERIVATIVES | Diazo compounds | Organic acids | homogenous catalysis | amination | photocatalysis | carboxylic acids
Journal Article