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Journal Article
Journal Article
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 11/2018, Volume 86, Issue 11, pp. 1211 - 1217
Journal Article
Journal Article
Journal of Cell Science, ISSN 0021-9533, 11/2013, Volume 126, Issue 21, pp. 5052 - 5061
The chemical genetic strategy in which mutational enlargement of the ATP-binding site sensitises of a protein kinase to bulky ATP analogues has proved to be an... 
Cdc25 | Wee1 | Mitosis | S. pombe | Analogue-sensitive kinase | TYROSINE PHOSPHATASE | CHEMICAL GENETICS | CONDITIONAL PHENOTYPE | SPINDLE POLE BODY | PROTEIN-KINASE | S-POMBE | CELL BIOLOGY | NUCLEAR-ENVELOPE | CELL-DIVISION CYCLE | MITOTIC COMMITMENT | SCHIZOSACCHAROMYCES-POMBE | Schizosaccharomyces pombe Proteins - chemistry | Protein-Tyrosine Kinases - metabolism | Phosphoprotein Phosphatases - metabolism | Casein Kinase II - genetics | Mutation, Missense | Cell Cycle Proteins - chemistry | Schizosaccharomyces - genetics | Protein-Tyrosine Kinases - genetics | Adenosine Triphosphate - metabolism | Enzyme Inhibitors - chemistry | Protein-Tyrosine Kinases - chemistry | Schizosaccharomyces pombe Proteins - metabolism | Cell Cycle Proteins - genetics | Conserved Sequence | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Protein Structure, Tertiary | Phenylalanine - metabolism | Schizosaccharomyces pombe Proteins - genetics | Enzyme Inhibitors - metabolism | Methionine - metabolism | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Nuclear Proteins - chemistry | Adenosine Triphosphate - analogs & derivatives | Casein Kinase II - chemistry | Phosphoprotein Phosphatases - genetics | Phenylalanine - genetics | Schizosaccharomyces - enzymology | Protein-Serine-Threonine Kinases - chemistry | Casein Kinase II - metabolism | Methionine - genetics | Schizosaccharomyces - cytology | Amino Acid Substitution | Index Medicus
Journal Article
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 03/2019, Volume 73, Issue 10, pp. 1149 - 1169
Eukaryotic cells can respond to diverse stimuli by converging at serine-51 phosphorylation on eukaryotic initiation factor 2 alpha (eIF2α) and activate the... 
atherosclerosis | lipid-induced inflammation | dietary fats | inflammasome | metabolic inflammation | integrated stress response | interleukin-1β | CARDIAC & CARDIOVASCULAR SYSTEMS | INFLAMMASOME ACTIVATION | KINASE | RISK | ENDOPLASMIC-RETICULUM STRESS | DISCOVERY | UNFOLDED PROTEIN RESPONSE | CARDIOVASCULAR-DISEASE | FATS | INHIBITOR | PROGRESSION | interleukin-1b | Medical research | Nervous system diseases | Phosphatases | Interleukins | Proteases | Atherosclerosis | Medicine, Experimental | Dietary fat | Oxidative stress | Atherogenesis | Phosphorylation | Laboratories | Serine | Interleukin | Lipids | Infections | Activation | Kinases | Macrophages | Phosphatase | Inflammatory diseases | Proteins | Lon protein | Mitochondria | Cell activation | Protease | Tumor necrosis factor-TNF | Lipid metabolism | Stress response | Tensin | Obesity | Neurodegenerative diseases | Secretion | Hyperlipidemia | Inflammation | IL-1β | Organelles | Fatty acids | Studies | Signaling | Inhibitors | Diet | Arteriosclerosis | Parkin protein | Fats | Mutation | Endoplasmic reticulum | ATF4, activating transcription factor 4 | CCL2, C-D motif ligand-2 | Parkin, Parkinson juvenile disease protein 2 | siRNA, silencer RNA | mtROS, mitochondrial reactive oxygen species | enhancer-binding protein beta homologous protein | CHOP, CCAT | UPR, unfolded protein response | GAS, Group A Streptococcus | LONP1, Lon protease 1 | PERK, protein kinase R-like endoplasmic reticulum kinase | CVD, cardiovascular disease(s) | PINK1, phosphatase and tensin-induced putative kinase1 | BMDM, bone marrow–derived macrophages | TNF, tumor necrosis factor | eIF2α kinase | SFA, saturated fatty acid | IRE1, inositol-requiring enzyme-1 | IL, interleukin | NLRP3, Nod-like receptor family, pyrin domain-containing protein-3 | ASKA, ATP-analog sensitive kinase allele | eIF2α, eukaryotic initiation factor 2 alpha | eIF2B, eukaryotic initiation factor 2B | PA, palmitate | ER, endoplasmic reticulum | ISR, integrated stress response
Journal Article
Journal Article
Journal Article