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European Heart Journal, ISSN 0195-668X, 08/2015, Volume 36, Issue 30, pp. 1990 - 1997
Journal Article
Circulation, ISSN 0009-7322, 03/2019, Volume 139, Issue 11, pp. 1354 - 1365
BACKGROUND:The morbidity and mortality of patients with functional mitral regurgitation (MR) remain high, but no pharmacological therapy has been proven... 
Receptors | Mitral valve insufficiency | Research | Drug therapy | Angiotensin
Journal Article
Lancet, The, ISSN 0140-6736, 10/2012, Volume 380, Issue 9851, pp. 1387 - 1395
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Journal Article
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Journal Article
Circulation, 03/2019, Volume 139, Issue 11, pp. 1354 - 1365
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 5791 - 13
Angiotensin receptor blocker-neprilysin inhibitor (ARNi) therapy improves the prognosis of heart failure patients. However, the mechanisms remain unclear. This... 
HYPERTROPHY | AUGMENTATION | ANGIOGENESIS | MULTIDISCIPLINARY SCIENCES | TACHYCARDIA | RABBIT MODEL | LCZ696 | DYSFUNCTION | CONTRIBUTES | EXPRESSION | LEFT-VENTRICULAR FUNCTION | Heart failure | Myocardial infarction | Contractility | Connective tissue growth factor | Beta blockers | Muscle contraction | Angiogenesis | Computed tomography | Perfusion | Fibrosis | Angiotensin | Myocardium | Neprilysin | Heart diseases
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 11/2019, Volume 74, Issue 18, pp. 2326 - 2327
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 10/2013, Volume 94, Issue 4, pp. 445 - 448
Journal Article
Journal Article
American Journal of Hypertension, ISSN 0895-7061, 12/2015, Volume 28, Issue 12, pp. 1409 - 1417
BACKGROUND LCZ696, an angiotensin receptor-neprilysin inhibitor, has recently been demonstrated to exert more beneficial effects on hypertensive or heart... 
angiotensin | blood pressure | cardiovascular protection | neprilysin | dual inhibition | hypertension | METABOLIC SYNDROME | EFFICACY | HEART-FAILURE | RATS | NEUTRAL ENDOPEPTIDASE INHIBITOR | PRESERVED EJECTION FRACTION | NATRIURETIC PEPTIDE SYSTEM | ANGIOEDEMA | BIOLOGY | DOUBLE-BLIND | PERIPHERAL VASCULAR DISEASE | Fibrosis - drug therapy | Tetrazoles - pharmacology | Sodium, Dietary - adverse effects | Angiotensin Receptor Antagonists - pharmacology | Endothelium, Vascular - drug effects | Hypertension - drug therapy | Male | Aminobutyrates - pharmacology | Cyclic GMP - blood | Aminobutyrates - therapeutic use | Hypertension - etiology | Valsartan - pharmacology | Hypertension - blood | Valsartan - therapeutic use | Inflammation - drug therapy | Blood Pressure - drug effects | Vascular Remodeling - drug effects | Drug Evaluation, Preclinical | Rats, Inbred SHR | Cardiomegaly - drug therapy | Sodium, Dietary - urine | Myocardium - pathology | Random Allocation | Animals | Neprilysin - antagonists & inhibitors | Heart - drug effects | Tetrazoles - therapeutic use | Oxidative Stress - drug effects | Angiotensin Receptor Antagonists - therapeutic use | Circadian Rhythm - drug effects | Hypertension | Care and treatment | Cardiac patients | Angiotensin II receptor blockers | Dosage and administration | Cardiovascular diseases | Health aspects | Risk factors
Journal Article
by Zhao, MY and Xin, YG and Li, JL and Cao, XF and Liu, XJ
MEDICINE, ISSN 0025-7974, 09/2019, Volume 98, Issue 39, p. e17296
The angiotensin-receptor-neprilysin inhibitor (ARNI) reduced cardiovascular deaths and heart failure hospitalization in patients with heart failure of reduced... 
hospitalization | PREVALENCE | non-HFrEF | TRIAL | SHIFT | MEDICINE, GENERAL & INTERNAL | RISK-FACTOR | SACUBITRIL/VALSARTAN | neprilysin inhibitor | OUTCOMES | DYSFUNCTION | quality of life | ASSOCIATION | Heart failure | Antihypertensive drugs | Usage | Drug therapy | Patient outcomes | Angiotensin II receptor blockers
Journal Article