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Current Medicinal Chemistry, ISSN 0929-8673, 01/2012, Volume 19, Issue 2, pp. 239 - 280
Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole ring are readily able to bind with a variety of enzymes and receptors in... 
Triazole | Antifungal | Antidiabetic | Triazolium | Anticonvulsant | Antibacterial | Antihistaminic | Antitubercular | Analgesic | Anti-obesitic | Antiparasitic | Antiviral | Anticancer | Anti-inflammatory | Anti-neuropathic | A ADENOSINE RECEPTOR | analgesic | antibacterial | anticancer | triazole | CLICK CHEMISTRY APPROACH | antihistaminic | ANTIBACTERIAL ACTIVITY | anti-inflammatory | BIOLOGICAL EVALUATION | PHARMACOLOGY & PHARMACY | anti-neuropathic | CHEMISTRY, MEDICINAL | INOSINE MONOPHOSPHATE DEHYDROGENASE | anticonvulsant | BIOCHEMISTRY & MOLECULAR BIOLOGY | EFFICIENT SYNTHESIS | PHARMACOLOGICAL IN-VITRO | AZOLE ANTIFUNGAL AGENTS | antitubercular | anti-obesitic | triazolium | antiviral | antiparasitic | antidiabetic | HISTONE DEACETYLASE INHIBITORS | ANTIMICROBIAL ACTIVITY | Antifungal Agents - pharmacology | Analgesics - pharmacology | Antiviral Agents - pharmacology | Antitubercular Agents - chemistry | Anti-Inflammatory Agents - pharmacology | Triazoles - chemistry | Antitubercular Agents - pharmacology | Antifungal Agents - chemistry | Hypoglycemic Agents - chemistry | Antineoplastic Agents - chemistry | Anticonvulsants - pharmacology | Hypoglycemic Agents - pharmacology | Triazoles - pharmacology | Anti-Inflammatory Agents - chemistry | Analgesics - chemistry | Antiviral Agents - chemistry | Anti-Bacterial Agents - chemistry | Anticonvulsants - chemistry | Antiparasitic Agents - pharmacology | Anti-Bacterial Agents - pharmacology | Antineoplastic Agents - pharmacology | Antiparasitic Agents - chemistry
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 2011, Volume 34, Issue 5, pp. 655 - 659
The anti-inflammatory agent etodolac is used worldwide and it has a good gastrointestinal safety profile. Etodolac consists of two enantiomers, S- and... 
Journal Article
日本レーザー医学会誌, ISSN 0288-6200, 2018, Volume 38, Issue 4, pp. 439 - 445
「要旨」関節リウマチの治療(RA)は20年以上にわたり, 劇的な変革期にある. 薬物治療, 特にメトトレキサートや生物学的製剤の進化によって生み出されたと言えよう. RA治療の達成目標は世界標準として定められるようになった. RAは疼痛と関節腫脹を特徴とする慢性炎症性疾患である.... 
Journal Article
日本ペインクリニック学会誌, ISSN 1340-4903, 2010, Volume 17, Issue 4, pp. 478 - 484
目的:神経障害痛の発症機序にミクログリア細胞の関与が示唆されている.ミクログリア細胞の活性は抗生物質ミノサイクリンで抑制されることが報告されているので,神経障害痛発現に対するミノサイクリンの抑制効果を検討した.方法:神経障害痛モデルはマウスの坐骨神経を部分結紮し,作製した.痛みの強さはvon Frey... 
ミクログリア | 神経障害痛 | 脊髄 | ミノサイクリン
Journal Article
Japanese Journal of Pharmacology, ISSN 0021-5198, 2001, Volume 87, Issue 3, pp. 214 - 225
We studied the effects of OT-7100 (5-n-buty1-7-(3, 4, 5-trimethoxybenzoylamino)pyrazolo [1, 5-a]pyrimidine), a novel analgesic compound, on the inhibitory... 
Journal Article
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