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Journal Article
Critical Care Medicine, ISSN 0090-3493, 08/2012, Volume 40, Issue 8, pp. 2320 - 2326
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2019, Volume 512, Issue 3, pp. 571 - 576
We report the production and application of a recombinant IgCw molecule, which is composed of only the constant domains of the heavy (C ) and light (C )... 
IgCw | Reference antibody | Antibody fragment | Isotype control | Constant region | PROTEIN | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIBODY | SECRETION | Immunoglobulin G | Phosphatases
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2018, Volume 24, Issue 5, pp. 610 - 616
In the absence of an effective and safe vaccine against HIV-1, the administration of broadly neutralizing antibodies (bNAbs) represents a logical alternative... 
POTENT HIV-ANTIBODIES | SUPPRESSES VIREMIA | MEDICINE, RESEARCH & EXPERIMENTAL | VIRUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TREATMENT INTERRUPTION | HUMANIZED MICE | CELL BIOLOGY | INDIVIDUALS | BROADLY NEUTRALIZING ANTIBODIES | GLYCAN RECOGNITION | MACAQUES | HUMAN MONOCLONAL-ANTIBODIES | Dose-Response Relationship, Immunologic | Humans | Neutralization Tests | Macaca mulatta | Antibodies, Viral - blood | Antibodies, Neutralizing - immunology | HEK293 Cells | Protein Domains | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Simian Immunodeficiency Virus - immunology | Antibody Formation - immunology | Mucous Membrane - virology | Crystallization | Antibodies, Monoclonal - pharmacokinetics | Probability | Treatment Outcome | Mutation - genetics | Simian Acquired Immunodeficiency Syndrome - blood | Simian Acquired Immunodeficiency Syndrome - prevention & control | Injections | Animals | Mucous Membrane - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Antibodies, Monoclonal - administration & dosage | Immunoglobulins | Intravenous administration | Mucosa | Viruses | Radioactive half-life | Infections | Immunoprophylaxis | Infusion | Coding | Human immunodeficiency virus--HIV | Monoclonal antibodies | Intravenous infusion | Mutation | Half life | Neutralization | Index Medicus
Journal Article
Journal of Immunological Methods, ISSN 0022-1759, 01/2019, Volume 464, pp. 57 - 63
Antibody-based diagnostics and therapeutics have huge commercial value. However, applications of antibodies are often limited by instability, particularly for... 
Complementarity determining region H3 | Protein stabilisation | Antibody engineering | Cysteine mutations | Single-chain antibody fragment
Journal Article
1993, ISBN 9780121852757, Volume 13., xvii, 396
Book
Journal of Neurochemistry, ISSN 0022-3042, 06/2016, Volume 137, Issue 5, pp. 820 - 837
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 03/2019, Volume 29, Issue 6, pp. 786 - 790
The PD-1 immune checkpoint pathway is a highly validated target for cancer immunotherapy. Despite the potential advantages of small molecule inhibitors over... 
PD-L1 inhibitor | Fragment-based screening | Structure-based design | Cancer drug discovery | Immunotherapy | CHEMISTRY, MEDICINAL | PROTEIN | CHEMISTRY, ORGANIC | ANTIBODY | RECEPTOR | CANCER | DISCOVERY | HIGH-AFFINITY LIGANDS | INHIBITORS | PHASE-I | Viral antibodies | Crystals | Antibodies | Drug discovery | Structure | Medical screening
Journal Article
Journal Article