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1. Full Text Antibody-dependent cellular cytotoxicity in HIV infection
by Forthal, DN and Finzi, A
AIDS, ISSN 0269-9370, 11/2018, Volume 32, Issue 17, pp. 2439 - 2451
Interactions between the Fc segment of IgG and its receptors (Fc gamma Rs) found on cells such as natural killer cells, monocytes, macrophages and neutrophils... 
NEUTRALIZING MONOCLONAL-ANTIBODIES | phagocytosis | INFECTIOUS DISEASES | MUCOSAL SHIV CHALLENGE | NATURAL-KILLER-CELLS | PBL-SCID MICE | MEDIATED CYTOTOXICITY | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | simian/human immunodeficiency virus | PRIMARY T-CELLS | simian immunodeficiency virus | CD4 | IN-VITRO | antibody-dependent cellular cytotoxicity | Fc receptor | HIV-1/SIV CHIMERIC VIRUS | VIROLOGY | HIV | natural killer cell | NEONATAL RHESUS MACAQUES
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2. Macrophage-mediated antibody-dependent cellular cytotoxicity
by Koren, Hillel S
1983, Immunology series, ISBN 9780824770112, Volume 21., xvii, 361
Macrophages | Antibody-dependent cell cytotoxicity | Cell-mediated cytotoxicity
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3. Full Text NK cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy
by Wang, Wei and Erbe, Amy K and Hank, Jacquelyn A and Morris, Zachary S and Sondel, Paul M
Frontiers in Immunology, ISSN 1664-3224, 2015, Volume 6, p. 368
Natural killer (NK) cells play a major role in cancer immunotherapies that involve tumor-antigen targeting by monoclonal antibodies (mAbs). NK cells express a... 
Natural killer cell | Therapeutic monoclonal antibody | Antibody-dependent cellular cytotoxicity | Immunotherapy | Cancer | HUMAN NEUROBLASTOMA-CELLS | NATURAL-KILLER-CELLS | COLONY-STIMULATING FACTOR | FC-GAMMA-RIIIA | ACUTE MYELOGENOUS LEUKEMIA | TARGETED INTERLEUKIN-2 THERAPY | IMMUNOLOGY | therapeutic monoclonal antibody | MHC CLASS-I | ANTI-GD2 MONOCLONAL-ANTIBODY | antibody-dependent cellular cytotoxicity | immunotherapy | NON-HODGKIN-LYMPHOMA | cancer | natural killer cell | ANTIGANGLIOSIDE GD2 ANTIBODY | Natural Killer cell
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4. Full Text Fc-galactosylation modulates antibody-dependent cellular cytotoxicity of therapeutic antibodies
by Thomann, Marco and Reckermann, Katharina and Reusch, Dietmar and Prasser, Jessica and Tejada, Max L
Molecular Immunology, ISSN 0161-5890, 05/2016, Volume 73, pp. 69 - 75
The therapeutic activity of monoclonal antibodies can involve immune cell mediated effector functions including antibody-dependent cellular cytotoxicity... 
Natural killer cell | CDC | Antibody | Fucosylation | IgG1 | Fc-glycan | Afucosylation | ADCC | Effector function | Galactosylation | EFFECTOR FUNCTIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR POLYMORPHISMS | GLYCOFORMS | MONOCLONAL-ANTIBODY | IMMUNOLOGY | CANCER | FUCOSE | LINE | GAMMA-RIII | BINDING | Galactose - metabolism | Immunoglobulin Fc Fragments - metabolism | Fucose - metabolism | Humans | Immunoglobulin G - chemistry | Receptors, IgG - chemistry | Antibody-Dependent Cell Cytotoxicity - immunology | Immunoglobulin Fc Fragments - chemistry | Glycosylation | Receptors, IgG - immunology | Receptors, IgG - metabolism | Immunoglobulin Fc Fragments - immunology | Killer Cells, Natural - immunology | Antibodies, Monoclonal - metabolism | Antibodies, Monoclonal - chemistry | Immunoglobulin G - metabolism | Monoclonal antibodies | Galactose | Health aspects | Analysis | Immunoglobulin G | Biopharmaceutics
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5. Full Text Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies
by Jegaskanda, Sinthujan and Job, Emma R and Kramski, Marit and Laurie, Karen and Isitman, Gamze and De Rose, Robert and Winnall, Wendy R and Stratov, Ivan and Brooks, Andrew G and Reading, Patrick C and Kent, Stephen J
Journal of Immunology, ISSN 0022-1767, 02/2013, Volume 190, Issue 4, pp. 1837 - 1848
A better understanding of immunity to influenza virus is needed to generate cross-protective vaccines. Engagement of Ab-dependent cellular cytotoxicity (ADCC)... 
FC-RECEPTOR | MEDIATED CYTO-TOXICITY | HIV | HEMAGGLUTININ | VACCINE | EXTRACELLULAR DOMAIN | MONOCLONAL-ANTIBODY | IMMUNOLOGY | VIRUS-INFECTED-CELLS | H1N1 INFLUENZA | RHESUS MACAQUES | Influenza A Virus, H1N1 Subtype - immunology | Macaca nemestrina | Hemagglutination Inhibition Tests - methods | Hemagglutinins, Viral - metabolism | Antibodies, Viral - metabolism | Humans | Middle Aged | Antibody-Dependent Cell Cytotoxicity - immunology | Child, Preschool | Cross Reactions - immunology | Protein Binding - immunology | Influenza Vaccines - metabolism | Young Adult | Animals | Influenza Vaccines - immunology | Antibody Specificity - immunology | Influenza Vaccines - therapeutic use | Adult | Influenza, Human - virology | Neutralization Tests - methods | Influenza A Virus, H1N1 Subtype - metabolism | Influenza, Human - prevention & control | Influenza, Human - immunology
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6. Full Text Influenza and Antibody-Dependent Cellular Cytotoxicity
by Von Holle, TA and Moody, MA
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 06/2019, Volume 10, p. 1457
Despite the availability of yearly vaccinations, influenza continues to cause seasonal, and pandemic rises in illness and death. An error prone replication... 
influenza | UNITED-STATES | animal models | MEDIATED CYTOTOXICITY | FC-RECEPTORS | PANDEMIC INFLUENZA | HUMAN MONOCLONAL-ANTIBODY | IMMUNOLOGY | vaccine targets | LYMPHOCYTE CYTOTOXICITY | mAb | VIRUS-INFECTED CELLS | A VIRUS | ADVISORY-COMMITTEE | antibodies | ADCC-antibody dependent cellular cytotoxicity | IMMUNIZATION PRACTICES | Influenza vaccines | Viral antibodies | Antibodies | Influenza | Vaccination | ADCC—antibody dependent cellular cytotoxicity
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7. Full Text Antibody-dependent cellular cytotoxicity against reactivated HIV-1-Infected Cells
by Lee, Wen Shi and Richard, Jonathan and Lichtfuss, Marit and Smith, Amos B and Park, Jongwoo and Courter, Joel R and Melillo, Bruno N and Sodroski, Joseph G and Kaufmann, Daniel E and Finzi, Andrés and Parsons, Matthew S and Kent, Stephen J
Journal of Virology, ISSN 0022-538X, 2016, Volume 90, Issue 4, pp. 2021 - 2030
Lifelong antiretroviral therapy (ART) for HIV-1 does not diminish the established latent reservoir. A possible cure approach is to reactivate the quiescent... 
HIV-1 GP120 | IN-VITRO | VIROLOGY | NK CELLS | MEDIATED CYTOTOXICITY | LATENTLY INFECTED-CELLS | IMMUNODEFICIENCY-VIRUS TYPE-1 | CD4(+) T-CELLS | EX-VIVO | VACCINE EFFICACY TRIAL | DISEASE PROGRESSION | CD4-Positive T-Lymphocytes - immunology | HIV-1 - immunology | HIV-1 - physiology | Antibody-Dependent Cell Cytotoxicity | HIV Antibodies - immunology | Humans | Middle Aged | Cells, Cultured | Adult | Male | CD4-Positive T-Lymphocytes - virology | Virus Activation
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8. Full Text Antibody-dependent cellular cytotoxicity and influenza virus
by Vanderven, Hillary A and Jegaskanda, Sinthujan and Wheatley, Adam K and Kent, Stephen J
Current Opinion in Virology, ISSN 1879-6257, 02/2017, Volume 22, pp. 89 - 96
Antibodies are a key defence against influenza infection and disease, but neutralizing antibodies are often strain-specific and of limited utility against... 
A VIRUS | NATURAL-KILLER-CELLS | NEUTRALIZING ANTIBODIES | VIROLOGY | WEST-NILE-VIRUS | IN-VIVO | HUMAN MONOCLONAL-ANTIBODY | INFECTED-CELLS | H1N1 INFLUENZA | VACCINE EFFICACY TRIAL | LYMPHOCYTE CYTOTOXICITY | Animals | Antibody-Dependent Cell Cytotoxicity | Humans | Disease Models, Animal | Influenza, Human - immunology | Orthomyxoviridae - immunology
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9. Full Text Antibody-Dependent Cellular Cytotoxicity Is Associated with Control of Pandemic H1N1 Influenza Virus Infection of Macaques
by Sinthujan Jegaskanda and Jason T. Weinfurter and Thomas C. Friedrich and Stephen J. Kent
Journal of Virology, ISSN 0022-538X, 05/2013, Volume 87, Issue 10, pp. 5512 - 5522
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
A VIRUS | CHALLENGE | VIROLOGY | NK CELLS | CYTO-TOXICITY | BROADLY NEUTRALIZING ANTIBODIES | VACCINE | MICE | GENERATION | CROSS-PROTECTIVE IMMUNITY | LYMPHOCYTES | Influenza A Virus, H1N1 Subtype - immunology | Gene Expression | Antibody-Dependent Cell Cytotoxicity - immunology | Bronchoalveolar Lavage Fluid - immunology | Macaca mulatta | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Primate Diseases - immunology | Antibodies, Viral - blood | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Cross Reactions | Animals | Killer Cells, Natural - immunology | Antibodies, Viral - immunology | Lysosomal-Associated Membrane Protein 1 - biosynthesis | Interferon-gamma - biosynthesis | Orthomyxoviridae Infections - immunology | Pathogenesis and Immunity
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10. Full Text Development of a kinetic antibody-dependent cellular cytotoxicity assay
by Kamen, Lynn and Thakurta, Tara and Myneni, Srividya and Zheng, Kai and Chung, Shan
Journal of Immunological Methods, ISSN 0022-1759, 05/2019, Volume 468, pp. 49 - 54
Antibody-dependent cellular cytotoxicity (ADCC) is an important mechanism of action (MOA) of monoclonal antibody (mAb) therapeutics. Target cells opsonized... 
Cellular imaging | Cell-based assay | Monoclonal antibody | Kinetic | Antibody-dependent cellular cytotoxicity | BIOCHEMICAL RESEARCH METHODS | IMMUNOLOGY | Immunoglobulin G | Therapeutics | Imaging systems | Fluorescence | Monoclonal antibodies | Homeopathy | Materia medica and therapeutics
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11. Full Text Breadth of HIV-1 Env-specific antibody-dependent cellular cytotoxicity: Relevance to global HIV vaccine design
by Madhavi, Vijaya and Wren, Leia H and Center, Rob J and Gonelli, Christopher and Winnall, Wendy R and Parsons, Matthew S and Kramski, Marit and Kent, Stephen J and Stratov, Ivan
AIDS, ISSN 0269-9370, 08/2014, Volume 28, Issue 13, pp. 1859 - 1870
Objective: The objective of this study is to determine the breadth of HIV-1 Env-specific antibody-dependent cellular cytotoxicity (ADCC) in HIV controllers and... 
HIV-1 | Glycosylation | Natural killer cells | Env | Antibody-dependent cellular cytotoxicity | HIV controllers | INFECTIOUS DISEASES | MEDIATED CYTOTOXICITY | NEUTRALIZING ANTIBODY | SLOW PROGRESSORS | glycosylation | IMMUNOLOGY | T-LYMPHOCYTE | natural killer cells | RESPONSES | antibody-dependent cellular cytotoxicity | VIROLOGY | NK CELLS | EFFICACY TRIAL | DOUBLE-BLIND | INFECTION | DISEASE PROGRESSION | T-Lymphocytes, Cytotoxic - immunology | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | Middle Aged | AIDS Vaccines - immunology | Genotype | Male | HIV-1 - genetics | HIV-1 - classification | Epitopes - immunology | Young Adult | HIV Infections - immunology | HIV-1 - immunology | env Gene Products, Human Immunodeficiency Virus - genetics | HIV Antibodies - immunology | Adult | Female
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12. Full Text The HIV-1 gp120 CD4-bound conformation is preferentially targeted by antibody-dependent cellular cytotoxicity-mediating antibodies in sera from HIV-1-infected individuals
by Veillette, Maxime and Coutu, Mathieu and Richard, Jonathan and Batraville, Laurie-Anne and Dagher, Olina and Bernard, Nicole and Tremblay, Cécile and Kaufmann, Daniel E and Roger, Michel and Finzi, Andrés
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 1, pp. 545 - 551
Recent studies have linked antibody Fc-mediated effector functions with protection or control of human immunodeficiency type 1 (HIV-1) and simian... 
CD4 | PROTEIN | VIROLOGY | DENDRITIC CELLS | NK CELLS | DETERMINANTS | DISEASE | IMMUNODEFICIENCY-VIRUS TYPE-1 | RECEPTOR | ADCC | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | HIV-1 - immunology | Antibody-Dependent Cell Cytotoxicity | HIV Antibodies - immunology | Humans | Protein Binding | HIV Envelope Protein gp120 - metabolism | CD4 Antigens - metabolism | Cohort Studies
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13. Full Text Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family
by Mattia Bonsignori and Justin Pollara and M. Anthony Moody and Michael D. Alpert and Xi Chen and Kwan-Ki Hwang and Peter B. Gilbert and Ying Huang and Thaddeus C. Gurley and Daniel M. Kozink and Dawn J. Marshall and John F. Whitesides and Chun-Yen Tsao and Jaranit Kaewkungwal and Sorachai Nitayaphan and Punnee Pitisuttithum and Supachai Rerks-Ngarm and Jerome H. Kim and Nelson L. Michael and Georgia D. Tomaras and David C. Montefiori and George K. Lewis and Anthony DeVico and David T. Evans and Guido Ferrari and Hua-Xin Liao and Barton F. Haynes
Journal of Virology, ISSN 0022-538X, 11/2012, Volume 86, Issue 21, pp. 11521 - 11532
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
RESPONSES | VIROLOGY | RHESUS-MONKEYS | IMMUNODEFICIENCY-VIRUS TYPE-1 | SHIV CHALLENGE | INFLUENZA-VIRUS | GP120 | HUMAN MONOCLONAL-ANTIBODIES | ADCC | RECEPTOR-BINDING | NEUTRALIZING-ANTIBODY | Genes, Immunoglobulin Heavy Chain | HIV-1 - immunology | Antibody-Dependent Cell Cytotoxicity | HIV Antibodies - immunology | Humans | AIDS Vaccines - immunology | Female | Male | AIDS Vaccines - administration & dosage | Human Experimentation | Vaccines and Antiviral Agents
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14. Full Text Influenza-specific antibody-dependent cellular cytotoxicity: Toward a universal influenza vaccine
by Jegaskanda, Sinthujan and Reading, Patrick C and Kent, Stephen J
Journal of Immunology, ISSN 0022-1767, 07/2014, Volume 193, Issue 2, pp. 469 - 475
There is an urgent need for universal influenza vaccines that can control emerging pandemic influenza virus threats without the need to generate new vaccines... 
A VIRUS | PROTECTS MICE | MEDIATED CYTO-TOXICITY | FC-RECEPTORS | SEASONAL INFLUENZA | EFFECTOR FUNCTION | PANDEMIC H1N1 VIRUS | IMMUNOLOGY | VIRUS-INFECTED-CELLS | STALK-SPECIFIC ANTIBODIES | LYMPHOCYTE CYTOTOXICITY | Models, Immunological | Animals | Influenza Vaccines - immunology | Immunoglobulin G - immunology | Humans | Antibody-Dependent Cell Cytotoxicity - immunology | Antibodies, Viral - immunology | Influenza, Human - virology | Orthomyxoviridae - physiology | Host-Pathogen Interactions - immunology | Influenza, Human - immunology | Orthomyxoviridae - immunology
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15. Full Text Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection
by Acharya, Priyamvada and Tolbert, William D and Gohain, Neelakshi and Wu, Xueji and Yu, Lei and Liu, Tongyun and Huang, Wensheng and Huang, Chih-Chin and Kwon, Young Do and Louder, Robert K and Luongo, Timothy S and McLellan, Jason S and Pancera, Marie and Yang, Yongping and Zhang, Baoshan and Flinko, Robin and Foulke, James S and Sajadi, Mohammad M and Kamin-Lewis, Roberta and Robinson, James E and Martin, Loïc and Kwong, Peter D and Guan, Yongjun and DeVico, Anthony L and Lewis, George K and Pazgier, Marzena
Journal of Virology, ISSN 0022-538X, 2014, Volume 88, Issue 21, pp. 12895 - 12906
The RV144 vaccine trial implicated epitopes in the C1 region of gp120 (A32-like epitopes) as targets of potentially protective antibody-dependent cellular... 
VAGINAL SHIV CHALLENGE | FC-RECEPTOR | VIROLOGY | SIMIAN IMMUNODEFICIENCY VIRUS | GP120 INNER DOMAIN | EFFECTOR FUNCTION | CD4-INDUCED EPITOPES | ENVELOPE GLYCOPROTEIN | MONOCLONAL-ANTIBODY | MACAQUES | ANTIGENIC PROPERTIES | Antibody-Dependent Cell Cytotoxicity | Humans | Models, Molecular | Crystallography, X-Ray | HIV Antibodies - chemistry | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | HIV-1 - immunology | HIV Antibodies - immunology | Immunoglobulin Fab Fragments - chemistry | Protein Binding | Protein Conformation | Epitopes - chemistry | HIV Envelope Protein gp120 - chemistry | Immunoglobulin Fab Fragments - immunology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Structure and Assembly
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