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European journal of medicinal chemistry, ISSN 0223-5234, 05/2015, Volume 96, pp. 491 - 503
Antiproliferative | Immunosuppressive | Phthalimide | Thiosemicarbazone | Thiazolidinone | Thiazole | Immunomodulation | Antineoplastic Agents - chemical synthesis | Cytokines - analysis | Humans | Cells, Cultured | Models, Molecular | Crystallography, X-Ray | Male | Phthalimides - chemistry | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Dose-Response Relationship, Drug | Phthalimides - pharmacology | Animals | Phthalimides - chemical synthesis | Lymphocytes - drug effects | Drug Design | Macrophages - drug effects | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Molecular Structure | Drug Screening Assays, Antitumor | Prevention | Cancer | Index Medicus
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 04/2016, Volume 24, Issue 8, pp. 1898 - 1908
Topoisomerase | Pyrazoline derivatives | ATP-competitive inhibitor | Antiproliferative activity | Pyrazoles - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Structure-Activity Relationship | DNA-Binding Proteins - metabolism | Dose-Response Relationship, Drug | Topoisomerase Inhibitors - pharmacology | Topoisomerase Inhibitors - chemical synthesis | Pyrazoles - chemistry | Biocatalysis - drug effects | Adenosine Triphosphate - metabolism | Drug Design | Antigens, Neoplasm - metabolism | Antineoplastic Agents - pharmacology | Molecular Structure | Pyrazoles - pharmacology | Cell Survival - drug effects | DNA Topoisomerases, Type II - metabolism | DNA-Binding Proteins - antagonists & inhibitors | DNA Topoisomerases, Type I - metabolism | Antineoplastic Agents - chemistry | Binding, Competitive - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Molecular Docking Simulation | Topoisomerase Inhibitors - chemistry | Drug Screening Assays, Antitumor | Index Medicus
Journal Article
Medicinal chemistry research, ISSN 1054-2523, 12/2018, Volume 27, Issue 11, pp. 2414 - 2425
Biochemistry, general | SH-SY5Y | Chalcones | Biomedicine | Antiproliferative activity | Neuroblastoma | Pharmacology/Toxicology | Cell Biology | 2D-QSAR | Cancer | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Analysis | Resveratrol | 5-Fluorouracil | Toxicity | Two dimensional models | Cytotoxicity | Selectivity | Tumor cell lines | Structure-activity relationships | Carbonyl groups | Molecular modelling | Fibroblasts | Two dimensional analysis | Viability | Lipophilicity | Carbonyls
Journal Article
Journal of ethnopharmacology, ISSN 0378-8741, 09/2014, Volume 155, Issue 2, pp. 1076 - 1085
Rhinella schneideri | Argininyl bufadienolides | Bufo | Antiproliferative activity | Brazilian pantanal | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Integrative & Complementary Medicine | Plant Sciences | Science & Technology | Bufonidae | Humans | Esters | Antineoplastic Agents - administration & dosage | Bufanolides - administration & dosage | Chromatography, High Pressure Liquid | Paraguay | Tandem Mass Spectrometry | Antineoplastic Agents - isolation & purification | Brazil | Inhibitory Concentration 50 | Antineoplastic Agents - pharmacology | Bufanolides - isolation & purification | Fibroblasts - metabolism | Cell Line | Amphibian Venoms - chemistry | Neoplasms - drug therapy | Animals | Fibroblasts - drug effects | Cell Line, Tumor | HL-60 Cells | Bufanolides - pharmacology | Cell Proliferation - drug effects | Neoplasms - pathology | Drug Screening Assays, Antitumor | Index Medicus
Journal Article
European journal of medicinal chemistry, ISSN 0223-5234, 04/2014, Volume 76, pp. 539 - 548
Antiproliferative | Microarray | Coumarin | Hydrazide–hydrazone | Caspases 3/7 | Apoptosis | Hydrazide-hydrazone | Caspase 7 - metabolism | Magnetic Resonance Spectroscopy | Humans | Mass Spectrometry | Caspase 3 - metabolism | Cell Line, Tumor | Coumarins - chemistry | Antineoplastic Agents - pharmacology | Antineoplastic Agents - chemistry | Hydrazones - chemistry | Drug Screening Assays, Antitumor | Anthracyclines | Care and treatment | DNA microarrays | Analysis | Leukemia | Drugstores | Coumarins | Drug resistance | Cancer | Index Medicus
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 08/2012, Volume 20, Issue 15, pp. 4820 - 4829
6H-Indolo[2,3-b]quinolines | 5H-Indolo[2,3-b]quinolines | Anticancer agents | Antiproliferative acivity | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Spermatozoa - chemistry | Stereoisomerism | Antineoplastic Agents - chemical synthesis | Humans | Indoles - chemical synthesis | BALB 3T3 Cells | Male | Structure-Activity Relationship | Quinolines - pharmacology | Dose-Response Relationship, Drug | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Molecular Structure | Tumor Cells, Cultured | DNA - drug effects | Alkaloids - pharmacology | Salmon | Quinolines - chemistry | Antineoplastic Agents - chemistry | Spermatozoa - drug effects | Quinolines - chemical synthesis | DNA - chemistry | Animals | Fibroblasts - drug effects | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Indoles - chemistry | Alkaloids - chemistry | Drug Screening Assays, Antitumor | Universities and colleges | Index Medicus
Journal Article
Environmental toxicology and pharmacology, ISSN 1382-6689, 2011, Volume 32, Issue 3, pp. 336 - 348
Emergency | Sesquiterpene | Flavonoids | Antiproliferative effect | Teucrium ramosissimum | Antioxidant activity | Pharmacology & Pharmacy | Environmental Sciences & Ecology | Toxicology | Life Sciences & Biomedicine | Science & Technology | Environmental Sciences | Leukemia - pathology | Antioxidants - chemistry | Apoptosis - drug effects | Humans | Structure-Activity Relationship | Flavones - chemistry | Flavonoids - pharmacology | Molecular Structure | Teucrium - chemistry | Tunisia | Flavones - pharmacology | Plant Leaves - chemistry | Plants, Medicinal - chemistry | Sesquiterpenes - chemistry | Magnetic Resonance Spectroscopy | Leukemia - drug therapy | Antineoplastic Agents, Phytogenic - chemistry | Antioxidants - pharmacology | K562 Cells | Cell Line, Tumor | Cell Proliferation - drug effects | Sesquiterpenes - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | Flavonoids - chemistry | Drug Screening Assays, Antitumor | Antioxidants | Oncology, Experimental | Sesquiterpenes | Leukemia | Research | Cancer | Isoflavones | Index Medicus | Life Sciences
Journal Article
European journal of medicinal chemistry, ISSN 0223-5234, 06/2013, Volume 64, pp. 99 - 110
Antiproliferative | Hybrid | Urea | Dithiocarbamate | 1,2,3-Triazole | Apoptosis | Apoptosis - drug effects | Triazoles - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Structure-Activity Relationship | Thiocarbamates - chemistry | Antineoplastic Agents - chemistry | Urea - chemistry | Dose-Response Relationship, Drug | Triazoles - pharmacology | Thiocarbamates - pharmacology | Urea - analogs & derivatives | Drug Design | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Molecular Structure | Cell Cycle - drug effects | Urea - pharmacology | Drug Screening Assays, Antitumor | Triazoles | Index Medicus
Journal Article
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2007, Volume 17, Issue 13, pp. 3613 - 3617
Antiproliferative | Tubulin | Solid tumors | Heterocyclic ketones | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Carbazoles - chemistry | Chemistry, Pharmaceutical - methods | Models, Chemical | Sulfonamides - chemistry | Humans | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Drug Design | Ketones - chemistry | Cell Line, Tumor | Inhibitory Concentration 50 | Antimitotic Agents - pharmacology | Antineoplastic Agents - pharmacology | Tubulin - chemistry | Drug Screening Assays, Antitumor | Index Medicus
Journal Article
Coordination chemistry reviews, ISSN 0010-8545, 2009, Volume 253, Issue 1, pp. 235 - 249
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 05/2017, Volume 25, Issue 9, pp. 2666 -