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Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 06/2015, Volume 97, Issue 1, pp. 419 - 443
Journal Article
Journal Article
Journal Article
ChemMedChem, ISSN 1860-7179, 11/2018, Volume 13, Issue 21, pp. 2332 - 2348
The pathway by which HIV‐1 enters host cells is a prime target for novel drug discovery because of its critical role in the life cycle of HIV‐1. The HIV‐1... 
HIV-1 | ENV-pseudovirus | antiviral agents | reverse transcriptase | structure–activity relationships | DESIGN | INFECTIONS | CHEMISTRY, MEDICINAL | VARIANTS | CD4 | ENV CLONES | structure-activity relationships | SPECTRUM ANTI-HIV-1 ACTIVITY | IMMUNODEFICIENCY-VIRUS TYPE-1 | EARLY SUBTYPE | PHARMACOLOGY & PHARMACY | NEUTRALIZATION | BINDING | Anti-HIV Agents - pharmacology | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | Benzodioxoles - metabolism | Reverse Transcriptase Inhibitors - pharmacology | Structure-Activity Relationship | Virus Internalization - drug effects | Anti-HIV Agents - chemical synthesis | HIV Envelope Protein gp120 - metabolism | Leukocytes, Mononuclear - virology | Reverse Transcriptase Inhibitors - chemistry | Reverse Transcriptase Inhibitors - chemical synthesis | HIV-1 - chemistry | Thiadiazoles - chemistry | Protein Binding - drug effects | Benzodioxoles - chemistry | Molecular Structure | Anti-HIV Agents - metabolism | HIV Envelope Protein gp120 - chemistry | Thiadiazoles - metabolism | Binding Sites | Benzodioxoles - chemical synthesis | Thiadiazoles - pharmacology | Pyrroles - metabolism | Anti-HIV Agents - chemistry | Pyrroles - pharmacology | Pyrroles - chemical synthesis | Thiadiazoles - chemical synthesis | Pyrroles - chemistry | HIV-1 - enzymology | Molecular Docking Simulation | Reverse Transcriptase Inhibitors - metabolism | Benzodioxoles - pharmacology | DNA polymerases | Antiviral agents | Drug discovery | HIV (Viruses) | Glycoprotein | Viruses | Selectivity | Hydrophobicity | CD4 antigen | Inhibitors | Human immunodeficiency virus--HIV | Antiviral activity | Life cycle engineering | Binding sites | Glycoprotein gp120 | Life cycles
Journal Article
Journal Article
BIOCONJUGATE CHEMISTRY, ISSN 1043-1802, 11/2019, Volume 30, Issue 11, pp. 2844 - 2858
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/1998, Volume 41, Issue 6, pp. 787 - 797
4-Amino- and 4-guanidino-4H-pyran-6-carboxamides 4 and 5 related to zanamivir (GG167) are a new class of inhibitors of influenza virus sialidases.... 
A VIRUS | IN-VITRO | CHEMISTRY, MEDICINAL | RAY MOLECULAR-STRUCTURE | NEURAMINIDASE INHIBITORS | REPLICATION | ANALOGS | GG167 4-GUANIDINO-2,4-DIDEOXY-2,3-DEHYDRO-N-ACETYLNEURAMINIC ACID | ANTIINFLUENZA DRUGS | 2,3-DIDEHYDRO-2,4-DIDEOXY-4-GUANIDINYL-N-ACETYLNEURAMINIC ACID | RATIONAL DESIGN | Antiviral Agents - pharmacokinetics | Guanidines - pharmacology | Structure-Activity Relationship | Enzyme Inhibitors - chemical synthesis | Orthomyxoviridae Infections - enzymology | Sialic Acids - chemistry | Zanamivir | Enzyme Inhibitors - pharmacokinetics | Antiviral Agents - chemistry | Pyrans - chemistry | Enzyme Inhibitors - chemistry | Guanidines - chemical synthesis | Influenza B virus - drug effects | Pyrans - pharmacology | Orthomyxoviridae Infections - drug therapy | Influenza B virus - enzymology | Pyrans - chemical synthesis | Antiviral Agents - pharmacology | Enzyme Inhibitors - pharmacology | Injections, Intraperitoneal | Influenza A virus - enzymology | Administration, Intranasal | Guanidines - chemistry | Pyrans - pharmacokinetics | Animals | Sialic Acids - pharmacology | Antiviral Agents - chemical synthesis | Neuraminidase - antagonists & inhibitors | Sialic Acids - pharmacokinetics | Guanidines - pharmacokinetics | Mice | Influenza A virus - drug effects | 4-guanidino-4H-pyran-6-carboxamide | zanamivir | 4-amino-4H-pyran-6-carboxamide
Journal Article
Journal Article