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Journal Article
Molecular Immunology, ISSN 0161-5890, 09/2015, Volume 67, Issue 1, pp. 101 - 107
•Plasma C3 concentration correlates to BMI, fat distribution, blood pressure, MetS and diabetes.•C3a-desArg is generated in proportion to the C3 plasma... 
C3 | Metabolic syndrome (MetS) | Obesity | Apolipoproteins | C3a-desArg | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN-SECRETION | STELLATE CELLS | RECEPTOR | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | ANAPHYLATOXIN C5A | IN-VITRO | MESSENGER-RNA | SIGNALING PATHWAY | ACYLATION-STIMULATING PROTEIN | ADIPOSE-TISSUE | Diabetes Mellitus - pathology | Diabetes Mellitus - genetics | Obesity - immunology | Humans | Complement C5a - metabolism | Metabolic Syndrome - metabolism | Adipose Tissue - immunology | Cardiovascular Diseases - pathology | Lipid Metabolism - immunology | Cardiovascular Diseases - genetics | Complement C3a - genetics | Obesity - genetics | Receptors, Complement - metabolism | Adipose Tissue - metabolism | Apolipoproteins - genetics | Triglycerides - immunology | Receptors, Complement - genetics | Metabolic Syndrome - immunology | Complement C3a - metabolism | Cardiovascular Diseases - metabolism | Apolipoproteins - metabolism | Risk Factors | Adipose Tissue - pathology | Gene Expression Regulation | Diabetes Mellitus - metabolism | Apolipoproteins - immunology | Obesity - metabolism | Obesity - pathology | Triglycerides - metabolism | Cardiovascular Diseases - immunology | Receptors, Complement - immunology | Diabetes Mellitus - immunology | Metabolic Syndrome - genetics | Complement C5a - genetics | Insulin Resistance - immunology | Complement C3a - immunology | Complement C5a - immunology | Metabolic Syndrome - pathology | Triglycerides - genetics | Biological Sciences | Immunology | Naturvetenskap | Immunologi | Natural Sciences | Biologiska vetenskaper
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 12/2018, Volume 14, Issue 12, pp. 1589 - 1601
We tested the hypothesis that low plasma complement C3 is observationally and genetically associated with high risk of Alzheimer's disease (AD). We studied... 
Genetics | APOE | Mendelian randomization | Alzheimer's disease | Complement C3 | CLEARANCE | ACTIVATION | DEMENTIA | CALCIUM HYPOTHESIS | NEURODEGENERATION | CLINICAL NEUROLOGY | APOLIPOPROTEIN-E | AMYLOID-BETA PEPTIDE | PATHWAY | INNATE IMMUNITY | ADIPOSE-TISSUE | Medicine, Experimental | Medical research | Apolipoproteins | Risk factors
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 2017, Volume 58, Issue 9, pp. 1869 - 1883
APOC3 is produced mainly by the liver and intestine and approximately half of plasma APOC3 associates with HDL. Though it was believed that APOC3 associates... 
Metabolomics | Brown adipose tissue | High density lipoprotein | Lipidomics | White adipose tissue | Cholesterol efflux | white adipose tissue | HUMAN PLASMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CIII-INDUCED HYPERTRIGLYCERIDEMIA | TRIGLYCERIDE-RICH LIPOPROTEINS | 2-DIMENSIONAL GEL-ELECTROPHORESIS | HEPATIC-UPTAKE | DIET-INDUCED OBESITY | MASS-SPECTROMETRY | HIGH-DENSITY-LIPOPROTEIN | brown adipose tissue | metabolomics | IN-VIVO | high density lipoprotein | cholesterol efflux | lipidomics | TRANSGENIC MICE | Tumor Necrosis Factor-alpha - metabolism | Gene Transfer Techniques | Antioxidants - metabolism | Humans | Lipoproteins, HDL - metabolism | Oxidative Phosphorylation | Adipose Tissue, White - metabolism | Apolipoprotein C-III - genetics | Genetic Pleiotropy | Mitochondria - metabolism | Adenosine Triphosphate - biosynthesis | Cholesterol - metabolism | Animals | HEK293 Cells | Adenoviridae - genetics | RAW 264.7 Cells | Adipose Tissue, Brown - metabolism | Biological Transport - genetics | Mice | Energy Metabolism - genetics | Metabolic rate | Lipid composition | Adipose tissue | Nuclear magnetic resonance--NMR | Liver | Homeostasis | Apolipoproteins | Metabolism | Cytochrome c | ABCA1 protein | Proteins | Lipoproteins | Mitochondria | Intestine | Uncoupling protein 1 | Adenoviruses | Rodents | Green fluorescent protein | Metabolic activation | ATP-binding protein | Adipose tissue (brown) | Lipoproteins (high density) | Structure-function relationships
Journal Article
Blood, ISSN 0006-4971, 01/2010, Volume 115, Issue 2, pp. 379 - 387
Journal Article
Journal Article
Journal Article