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1. Full Text Induced folding in RNA recognition by Arabidopsis thaliana DCL1
by Suarez, Irina P and Burdisso, Paula and Benoit, Matthieu P. M. H and Boisbouvier, Jèrôme and Rasia, Rodolfo M
Nucleic acids research, ISSN 0305-1048, 06/2015, Volume 43, Issue 13, pp. 6607 - 6619
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Structure, Tertiary | RNA Folding | Ribonuclease III - metabolism | RNA-Binding Proteins - chemistry | Cell Cycle Proteins - metabolism | Models, Molecular | RNA - chemistry | Arabidopsis Proteins - metabolism | Cell Cycle Proteins - chemistry | Arabidopsis Proteins - chemistry | Intrinsically Disordered Proteins - chemistry | Protein Binding | Ribonuclease III - chemistry | Protein Stability | RNA-Binding Proteins - metabolism | RNA - metabolism | Index Medicus | Spleen | Leukemia, Myeloid | Humans | Biochemistry, Molecular Biology | Dose-Response Relationship, Drug | Life Sciences | Leukemia, T-Cell | Animals | Cytarabine | Time Factors | Arabinofuranosylcytosine Triphosphate | Arabinonucleotides | Biomolecules | Mice | Tumor Cells, Cultured | Deoxycytosine Nucleotides | Structural Biology
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2. Full Text Arabinonucleic Acids: 2′-Stereoisomeric Modulators of siRNA Activity
by Anzahaee, Maryam Yahyaee and Deleavey, Glen F and Le, Phuong Uyen and Fakhoury, Johans and Petrecca, Kevin and Damha, Masad J
Nucleic acid therapeutics, ISSN 2159-3337, 10/2014, Volume 24, Issue 5, pp. 336 - 343
Original Articles | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | RNA, Small Interfering - genetics | Luciferases - metabolism | Neuroglia - pathology | Stereoisomerism | Humans | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Luciferases - genetics | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Nucleic Acid Conformation | Genes, Tumor Suppressor | Genes, Reporter | Arabinonucleotides - genetics | Gene Expression | Nuclear Proteins - metabolism | Arabinonucleotides - chemical synthesis | High-Throughput Screening Assays | Arabinonucleotides - metabolism | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Luciferases - antagonists & inhibitors | Neuroglia - metabolism | HeLa Cells | RNA, Small Interfering - chemical synthesis | RNA, Small Interfering - metabolism | Ribonucleic acid--RNA | Brain cancer | Index Medicus
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3. Full Text Intravitreal Crystalline Drug Delivery for Intraocular Proliferation Diseases
by Cheng, Lingyun and Hostetler, Karl and Valiaeva, Nadya and Tammewar, Ajay and Freeman, William R and Beadle, James and Bartsch, Dirk-Uwe and Aldern, Kathy and Falkenstein, Iryna
Investigative ophthalmology & visual science, ISSN 0146-0404, 01/2010, Volume 51, Issue 1, pp. 474 - 481
Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Prodrugs - administration & dosage | Retina - drug effects | Arabinonucleotides - administration & dosage | Prodrugs - chemistry | Drug Delivery Systems | Dose-Response Relationship, Drug | Rats, Inbred BN | Arabinonucleotides - toxicity | Deoxyuracil Nucleotides - chemical synthesis | Retinal Neovascularization - prevention & control | Tonometry, Ocular | Vitreous Body | Vitreoretinopathy, Proliferative - prevention & control | Disease Models, Animal | Fluorescein Angiography | Rabbits | Vitreoretinopathy, Proliferative - pathology | Crystallization | Ophthalmoscopy | Rats | Arabinonucleotides - chemical synthesis | Injections | Animals | Deoxyuracil Nucleotides - administration & dosage | Prodrugs - toxicity | Deoxyuracil Nucleotides - toxicity | Retina - pathology | Retinal Neovascularization - pathology | Index Medicus
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4. Full Text Synthesis and Characterization of a Novel Liver-Targeted Prodrug of Cytosine-1-β-d-arabinofuranoside Monophosphate for the Treatment of Hepatocellular Carcinoma
by Boyer, Serge H and Sun, Zhili and Jiang, Hongjian and Esterbrook, Julie and Gómez-Galeno, Jorge E and Craigo, William and Reddy, K. Raja and Ugarkar, Bheemarao G and MacKenna, Deidre A and Erion, Mark D
Journal of medicinal chemistry, ISSN 0022-2623, 12/2006, Volume 49, Issue 26, pp. 7711 - 7720
Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Antineoplastic Agents - chemical synthesis | Male | Chromatography, High Pressure Liquid | Hepatocytes - metabolism | Cytidine Monophosphate - pharmacology | Tissue Distribution | Carcinoma, Hepatocellular - drug therapy | Cytidine Monophosphate - chemical synthesis | Liver - drug effects | Arabinonucleotides - pharmacokinetics | Bone Marrow - metabolism | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Arabinofuranosylcytosine Triphosphate - blood | Hepatocytes - drug effects | Bone Marrow - drug effects | Liver Neoplasms - drug therapy | Rats | Arabinonucleotides - chemical synthesis | Animals | Prodrugs - pharmacokinetics | Cytidine Monophosphate - analogs & derivatives | Arabinonucleotides - pharmacology | Cytidine Monophosphate - pharmacokinetics | Prodrugs - chemical synthesis | Mice | Prodrugs - pharmacology | Index Medicus
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5. Full Text Selection of 2′-Deoxy-2′-Fluoroarabino Nucleic Acid (FANA) Aptamers That Bind HIV‑1 Integrase with Picomolar Affinity
by Rose, Kevin M and Alves Ferreira-Bravo, Irani and Li, Min and Craigie, Robert and Ditzler, Mark A and Holliger, Philipp and DeStefano, Jeffrey J
ACS chemical biology, ISSN 1554-8929, 10/2019, Volume 14, Issue 10, pp. 2166 - 2175
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Sequence Alignment | SELEX Aptamer Technique | Base Sequence | Aptamers, Nucleotide - chemistry | HIV Integrase - chemistry | HIV-1 - enzymology | Arabinonucleotides - chemistry | RNA - chemistry | Index Medicus
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6. Full Text Mapping the affinity landscape of Thrombin-binding aptamers on 2 ' F-ANA/DNA chimeric G-Quadruplex microarrays
by Lietard, Jory and Abou Assi, Hala and Gomez-Pinto, Irene and Gonzalez, Carlos and Somoza, Mark M and Damha, Masad J
Nucleic acids research, ISSN 0305-1048, 02/2017, Volume 45, Issue 4, pp. 1619 - 1632
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | DNA - chemistry | Magnetic Resonance Spectroscopy | Oligonucleotide Array Sequence Analysis | Base Sequence | Aptamers, Nucleotide - chemistry | Models, Molecular | G-Quadruplexes | Organophosphorus Compounds - chemistry | Arabinonucleotides - chemistry | Index Medicus | Chemical Biology and Nucleic Acid Chemistry
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7. Full Text Ribonuclease A Inhibition by Carboxymethylsulfonyl‐Modified Xylo‐ and Arabinopyrimidines
by Datta, Dhrubajyoti and Dasgupta, Swagata and Pathak, Tanmaya
ChemMedChem, ISSN 1860-7179, 09/2014, Volume 9, Issue 9, pp. 2138 - 2149
docking | inhibitors | modified nucleosides | RNase A | pyrimidines | carboxymethylsulfonyls | Carboxymethylsulfonyls | Docking | Pyrimidines | Inhibitors | Modified nucleosides | RNaseA | Catalytic Domain - drug effects | Cytidine - chemistry | Arabinonucleotides - pharmacology | Computational Biology | Enzyme Inhibitors - pharmacology | Models, Molecular | Kinetics | Enzyme Inhibitors - chemical synthesis | Ribonuclease, Pancreatic - antagonists & inhibitors | Arabinonucleotides - chemical synthesis | Uridine - chemistry | Index Medicus
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8. Full Text Synthesis and antisense properties of 2β-f-arabinouridine modified oligonucleotides with 4-C-OMe substituent
by He, Xiao-Yang and Wang, Jing and Lu, Dan-Dan and Wang, Sheng-Qi
Molecules (Basel, Switzerland), ISSN 1420-3049, 09/2018, Volume 23, Issue 9, p. 2374
Chemical modification | Arabinonucleotide | Fluorine | Pseudohydrogen bond | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Nucleic Acid Denaturation | Oligonucleotides, Antisense - pharmacology | Phosphoric Diester Hydrolases - metabolism | Oligonucleotides, Antisense - chemical synthesis | Enzyme Stability | Oligonucleotides, Antisense - chemistry | Snake Venoms - enzymology | Uridine - chemical synthesis | Uridine - chemistry | Uridine - pharmacology | RNA modification | Automation | Oligonucleotides | Antisense oligonucleotides | Thymidine | Selectivity | Hybridization | Ribonucleic acid--RNA | Circular dichroism | Complement component C4 | Dichroism | Destabilization | Deoxyribonucleic acid--DNA | Sugar | Conformation | Index Medicus | pseudohydrogen bond | chemical modification | arabinonucleotide | fluorine
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9. Full Text Evaluating TNA stability under simulated physiological conditions
by Culbertson, Michelle C and Temburnikar, Kartik W and Sau, Sujay P and Liao, Jen-Yu and Bala, Saikat and Chaput, John C
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 05/2016, Volume 26, Issue 10, pp. 2418 - 2421
Threose nucleic acid | Biological stability | RNA analogue | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Oligonucleotides - chemistry | Phosphoric Diester Hydrolases - metabolism | Magnetic Resonance Spectroscopy | Arabinonucleotides - pharmacokinetics | Microsomes, Liver - drug effects | Drug Stability | Humans | Half-Life | Ribose - chemistry | Tetroses - chemistry | Oligonucleotides - pharmacokinetics | Phosphoric Diester Hydrolases - chemistry | Physiological aspects | Enzymes | Antisense RNA | Snakes | Liver | DNA | Index Medicus
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10. Full Text 2 '-Deoxy-2 '-fluoro-arabinonucleic acid: a valid alternative to DNA for biotechnological applications using charge transport
by Teo, Ruijie D and Smithwick, Elizabeth R and Migliore, Agostino
Physical chemistry chemical physics : PCCP, ISSN 1463-9076, 11/2019, Volume 21, Issue 41, pp. 22869 - 22878
Physical Sciences | Chemistry | Physics, Atomic, Molecular & Chemical | Chemistry, Physical | Physics | Science & Technology | Electronics | Biotechnology - methods | DNA - chemistry | Arabinonucleotides - chemistry | Molecular Dynamics Simulation | Index Medicus
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11. Full Text Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase
by Jackson, Lynnette N and Chim, Nicholas and Shi, Changhua and Chaput, John C
Nucleic acids research, ISSN 0305-1048, 07/2019, Volume 47, Issue 13, pp. 6973 - 6983
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Catalytic Domain | Geobacillus stearothermophilus - enzymology | Nucleic Acid Hybridization | DNA, Bacterial - metabolism | RNA-Directed DNA Polymerase - metabolism | Bacterial Proteins - chemistry | Models, Molecular | Templates, Genetic | Crystallography, X-Ray | DNA Polymerase I - chemistry | Structure-Activity Relationship | Arabinonucleotides - metabolism | RNA-Directed DNA Polymerase - isolation & purification | RNA-Directed DNA Polymerase - chemistry | Protein Binding | Bacterial Proteins - metabolism | Nucleosides - metabolism | Protein Conformation | Bacterial Proteins - isolation & purification | DNA Polymerase I - isolation & purification | DNA Polymerase I - metabolism | Index Medicus | Nucleic Acid Enzymes
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