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2012, Colloquium series on the genetic basis of human disease, ISBN 1615043780, Volume 1
Web Resource
2003, 1st ed., ISBN 9780123525512
Web Resource
Nature, ISSN 0028-0836, 10/2012, Volume 490, Issue 7420, pp. 367 - 372
The ATP-binding cassette (ABC) transporter BtuCD mediates the uptake of vitamin B-12 across the inner membrane of Escherichia coli. Previous structures have... 
DOMAIN | MULTIDRUG ABC TRANSPORTER | MECHANISM | CRYSTAL-STRUCTURE | MALTOSE TRANSPORTER | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | INTERMEDIATE | VIRULENCE | ATP-BINDING | PROTEIN COMPLEX
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 08/2013, Volume 54, Issue 8, pp. 2034 - 2048
Journal Article
FEMS Microbiology Reviews, ISSN 0168-6445, 2002, Volume 26, Issue 4, pp. 355 - 374
The initiation of replication is the central event in the bacterial cell cycle. Cells control the rate of DNA synthesis by modulating the frequency with which... 
Plasmid | Protein domain | ATP-binding DnaA box | DnaB helicase
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 04/2006, Volume 176, Issue 7, pp. 3877 - 3883
Human IL-1 family proteins are key mediators of the host response to infections, injury, and immunologic challenges. The mechanism by which IL-1 activates... 
EXTRACELLULAR ATP | RHEUMATOID-ARTHRITIS | IMMUNE-SYSTEM | IL-1-BETA RELEASE | NUCLEOTIDE RECEPTOR | INTERLEUKIN-1-BETA SECRETION | ATP-BINDING-SITE | GAMMA-INDUCING FACTOR | MICROGLIAL CELLS | IMMUNOLOGY | HUMAN MONOCYTES
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 09/2019, Volume 139, Issue 9, pp. 1985 - 1992.e10
ABCB5 is an ABC transporter that was shown to confer low-level multidrug resistance in cancer. In this study, we show that ABCB5 was mutated in 13.75% of the... 
CELLS | GENE | DRUG-RESISTANCE | EXPRESSION | ATP-BINDING | P-GLYCOPROTEIN | REVEALS | DERMATOLOGY | Index Medicus
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 09/2019, Volume 108, Issue 9, pp. 3130 - 3137
Liver dysfunction reduces systemic clearance of drugs that are primarily eliminated by the liver. However, liver dysfunction can cause a reduction in the... 
intestinal transporter(s) | pharmacokinetics | ATP-binding cassette (ABC) transporter(s) | disposition | intestinal absorption | absorption
Journal Article
BIOPHYSICAL JOURNAL, ISSN 0006-3495, 04/2019, Volume 116, Issue 8, pp. 1380 - 1385
Protein misfolding and overloaded proteostasis networks underlie a range of neurodegenerative diseases. No cures exist for these diseases, but developing... 
YEAST | HSP104 | BIOPHYSICS | RNA | PRION-LIKE DOMAINS | PROTEASOME | AGGREGATE FORMATION | CHAPERONES REDUCE | ATP BINDING | MODEL | ATPASES
Journal Article
Cancer Research, ISSN 0008-5472, 06/2008, Volume 68, Issue 12, pp. 4833 - 4842
Heat shock protein (lisp) 90 is an ATP-dependent molecular chaperone that maintains the active conformation of client oncoproteins in cancer cells. An isoform,... 
CANCER-CELLS | MOLECULAR CHAPERONE HSP90 | ACTIVATION | PROTEIN | ONCOLOGY | IN-VIVO | KINASE | ATP BINDING | RECEPTOR | SMOOTH-MUSCLE-CELLS | HISTONE DEACETYLASE INHIBITORS
Journal Article
2008, Blood-brain barrier : regulatory gatekeeper between brain and body
Web Resource
2008, Blood-brain barrier : understanding the regulatory gatekeeper between brain and body
Web Resource
by Wu, GL and Cheng, B and Qian, H and Ma, SM and Chen, Q
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 07/2019, Volume 17, Issue 28, pp. 6854 - 6859
The anti-malarial drug artemisinin (ART) possesses potent anti-inflammatory activity, yet its underlying mechanism of action has remained elusive. Here we... 
CHEMISTRY, ORGANIC | ANTIMALARIAL ACTIVITY | ATP BINDING | MAPK | NF-KAPPA-B | DERIVATIVES | ARTESUNATE
Journal Article
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