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Cell Metabolism, ISSN 1550-4131, 10/2017, Volume 26, Issue 4, p. 588
Dysregulation of the T.sub.h17/T.sub.reg balance is a key driver of autoimmunity. A new study by has revealed that small-molecule inhibition of... 
Autoimmunity
Journal Article
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, ISSN 1610-0379, 11/2018, Volume 16, Issue 11, pp. 1339 - 1358
Pathophysiologically, bullous autoimmune dermatoses are caused by autoantibodies directed against adhesion molecules or structural proteins of the skin and... 
Autoimmunity
Journal Article
Clinical Immunology, ISSN 1521-6616, 05/2017, Volume 178, p. 29
Mast cells (MCs) are innate immune cells that exert positive and negative immune modulatory functions capable to enhance or limit the intensity and/or duration... 
Autoimmunity
Journal Article
Acta Paediatrica, ISSN 0803-5253, 06/2017, Volume 106, Issue 6, p. 973
Journal Article
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, ISSN 1610-0379, 08/2018, Volume 16, Issue 8, pp. 1032 - 1035
Journal Article
Cytokine, ISSN 1043-4666, 11/2015, Volume 76, Issue 1, pp. 101 - 102
Cytokines of the Interleukin (IL)-6-family have essential functions in the control of inflammatory responses and immune defense. All members signal through the... 
Autoimmunity
Journal Article
Cytokine, ISSN 1043-4666, 11/2015, Volume 76, Issue 1, p. 64
In the past years, and clear pathogenic role was shown for Th17 cells in the development of autoimmune diseases. In particular, these cells were shown to play... 
Autoimmunity
Journal Article
Cytokine, ISSN 1043-4666, 11/2015, Volume 76, Issue 1, p. 71
Journal Article
Nature Immunology, ISSN 1529-2908, 11/2013, Volume 14, Issue 11, pp. 1166 - 1172
Sphingosine 1-phosphate (S1P) signaling regulates lymphocyte egress from lymphoid organs into systemic circulation. The sphingosine phosphate receptor 1 (S1P... 
Autoimmunity
Journal Article
Cytokine, ISSN 1043-4666, 11/2014, Volume 70, Issue 1, p. 74
IAP proteins limit RIPK3-dependent cell death, and caspase-8 and NLRP3-caspase-1 inflammasome activation of IL-1[beta], yet the mechanisms remain unclear. We... 
Autoimmunity
Journal Article
Cytokine, ISSN 1043-4666, 11/2014, Volume 70, Issue 1, p. 50
MDA5 is an essential intracellular sensor for several viruses, including picornaviruses, and elicits antiviral interferon (IFN) responses by recognizing viral... 
Autoimmunity
Journal Article
Cytokine, ISSN 1043-4666, 11/2014, Volume 70, Issue 1, p. 41
Helminth parasites typically establish chronic infections in the mammalian host which can persist for decades. Helminths evade protective host immune responses... 
Autoimmunity
Journal Article
Cytokine, ISSN 1043-4666, 11/2014, Volume 70, Issue 1, pp. 23 - 24
Microbes or endogenous danger signals trigger the assembly of cytosolic inflammasome receptors with the adapter ASC into speck-like aggregates. ASC specks... 
Autoimmunity
Journal Article
Cytokine, ISSN 1043-4666, 11/2014, Volume 70, Issue 1, p. 48
Type I Interferons are important contributors in autoimmunity. In multiple sclerosis (MS), an autoimmune disease affecting the central nervous system,... 
Autoimmunity
Journal Article
Autoimmunity Reviews, ISSN 1568-9972, 12/2016, Volume 15, Issue 12, p. 1210
Journal Article
Experimental Gerontology, ISSN 0531-5565, 01/2014, Volume 49, p. 55
Journal Article
Journal of Neuroimmunology, ISSN 0165-5728, 09/2013, Volume 262, Issue 1-2, p. 27
This study explores the consequences of deficiency in the autoimmune regulator (Aire) on the susceptibility to experimental autoimmune encephalomyelitis (EAE).... 
Autoimmunity
Journal Article
Nature Reviews: Drug Discovery, ISSN 1474-1776, 12/2012, Volume 12, Issue 1, pp. 51 - 63
Forkhead box P3 (FOXP3)-expressing regulatory T (T sub(Reg)) cells have a pivotal role in the regulation of immune responses and in the maintenance of... 
Autoimmunity
Journal Article
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