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Current Opinion in Immunology, ISSN 0952-7915, 02/2018, Volume 50, pp. 32 - 38
The inflammasome is a complex of proteins that through the activity of caspase-1 and the downstream substrates gasdermin D, IL-1β, and IL-18 execute an... 
AIM2 INFLAMMASOME | ACTIVATION | PROTEIN | PHOSPHORYLATION | CASPASE-1 AUTOPROTEOLYSIS | INFECTION | NLRP3 INFLAMMASOME | NLRC4 | IMMUNOLOGY | PYRIN INFLAMMASOME | CELL-DEATH
Journal Article
Basic and Clinical Pharmacology and Toxicology, ISSN 1742-7835, 2019
While a wide range of G protein-coupled receptors (GPCR) have emerged as prime targets for pharmacological intervention long ago, a distinct group of GPCR has... 
adhesion GPCR | cancer | G protein-coupled receptors | autoproteolysis | monobodies
Journal Article
Journal Article
CELL REPORTS, ISSN 2211-1247, 12/2017, Volume 21, Issue 12, pp. 3427 - 3444
The caspase activation and recruitment domain (CARD)-based inflammasome sensors NLRP1b and NLRC4 induce caspase-1-dependent pyroptosis independent of the... 
ANTHRAX LETHAL TOXIN | PATHWAYS | ACTIVATION | CAUSES AUTOINFLAMMATION | MUTATION | IL-1-BETA | INDUCTION | BACTERIAL | AUTOPROTEOLYSIS | CELL-DEATH | CELL BIOLOGY
Journal Article
Annals of Neurosciences, ISSN 0972-7531, 2014, Volume 21, Issue 1, pp. 28 - 31
Sonic Hedgehog (Shh) signalling cascade is one of the intricate signal transduction mechanisms that govern the precisely regulated developmental processes of... 
Neural tube pattern | Sonic hedgehog | Autoproteolysis | Lipidation | Notochord | Holoprosencephaly | Comp Review
Journal Article
The EMBO Journal, ISSN 0261-4189, 03/2012, Volume 31, Issue 6, pp. 1364 - 1378
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 02/2019, Volume 105, Issue 2, pp. 377 - 399
Inflammasomes are multimeric protein complexes that induce the cleavage and release of bioactive IL‐1β and cause a lytic form of cell death, termed pyroptosis.... 
metabolism | caspases | inflammasome | mitochondria | reactive oxygen species | INDUCED CELL-DEATH | AIM2 INFLAMMASOME | THIOREDOXIN-INTERACTING PROTEIN | K+ EFFLUX | CASPASE-1 AUTOPROTEOLYSIS | IMMUNOLOGY | INTERLEUKIN-1-BETA MATURATION | NALP3 INFLAMMASOME | CELL BIOLOGY | DIFFERENTIAL REQUIREMENT | GASDERMIN-D | HEMATOLOGY | NF-KAPPA-B
Journal Article