UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
b-site app cleaving enzyme 1 (528) 528
alzheimer's disease (497) 497
science & technology (486) 486
neurodegenerative diseases (374) 374
life sciences & biomedicine (361) 361
proteins (294) 294
secretase (266) 266
amyloid precursor protein (255) 255
alzheimers disease (227) 227
neurosciences (201) 201
animals (177) 177
humans (173) 173
neurosciences & neurology (172) 172
enzymes (170) 170
β-amyloid (160) 160
brain (156) 156
b-site app cleaving enzyme (142) 142
cognitive ability (142) 142
amyloid precursor protein secretases - metabolism (140) 140
mice (136) 136
alzheimer’s disease (130) 130
rodents (129) 129
peptides (125) 125
mental disorders (122) 122
aspartic acid endopeptidases - metabolism (121) 121
multidisciplinary sciences (121) 121
science & technology - other topics (121) 121
gene expression (109) 109
science (104) 104
medicine (103) 103
pathogenesis (102) 102
neuroscience (101) 101
dementia (100) 100
amyloid beta-peptides - metabolism (98) 98
biochemistry & molecular biology (96) 96
research article (93) 93
memory (92) 92
male (89) 89
amyloidogenesis (88) 88
bace1 (86) 86
hippocampus (85) 85
pathology (80) 80
cell biology (79) 79
amyloid beta-protein precursor - metabolism (78) 78
apoptosis (78) 78
neurodegeneration (77) 77
neurology (77) 77
phosphorylation (76) 76
inflammation (75) 75
animal models (74) 74
neuroprotection (72) 72
transgenic mice (71) 71
alzheimer disease - metabolism (70) 70
amyloid precursor protein secretases - genetics (70) 70
amyloid (69) 69
kinases (69) 69
signal transduction (68) 68
oxidative stress (67) 67
tau protein (65) 65
aspartic acid endopeptidases - genetics (64) 64
dementia disorders (64) 64
metabolism (62) 62
proteolysis (62) 62
plaques (61) 61
biology (60) 60
neurons (60) 60
presenilin 1 (59) 59
brain research (57) 57
female (56) 56
mice, transgenic (56) 56
mutation (54) 54
physical sciences (53) 53
alzheimer disease - pathology (52) 52
inhibition (52) 52
inhibitors (52) 52
chemistry (51) 51
disease models, animal (51) 51
aging (49) 49
alzheimer disease (49) 49
amyloid beta-protein (49) 49
genes (47) 47
cell culture (46) 46
clinical trials (44) 44
mice, inbred c57bl (44) 44
neurotoxicity (44) 44
medical research (43) 43
physiology (43) 43
alzheimer disease - genetics (42) 42
biochemistry (42) 42
pharmacology (42) 42
amyloid precursor protein secretases - antagonists & inhibitors (41) 41
disease (41) 41
nervous system (41) 41
transgenic animals (41) 41
analysis (40) 40
cell line, tumor (40) 40
studies (40) 40
toxicity (40) 40
age (39) 39
amyloid beta-protein precursor - genetics (39) 39
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Molecular neurobiology, ISSN 0893-7648, 6/2018, Volume 55, Issue 6, pp. 4612 - 4623
...) cleaving enzymes under Aβ42 oligomers (AβO) toxicity in pheochromocytoma cells (PC12) in culture. Moreover, the effect of endogenously liberated... 
Sirtuins | APP | Neuroprotection | Neurosciences | PARPs | Alzheimer’s disease | Secretases | Neurobiology | Cell Biology | SIRTs | Neurology | Biomedicine | Poly(ADP-ribose) polymerases | Amyloid | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Amyloid Precursor Protein Secretases - genetics | Cell Survival - drug effects | Transcription, Genetic - drug effects | Amyloid beta-Peptides - toxicity | RNA, Messenger - genetics | Rats | Mitochondria - metabolism | Mitochondria - drug effects | RNA, Messenger - metabolism | PC12 Cells | Gene Expression Regulation - drug effects | Phenanthrenes - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | Amyloid Precursor Protein Secretases - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Animals | Models, Biological | Cell Death - drug effects | Sirtuins - genetics | Sirtuins - metabolism | NAD - metabolism | Enzymes | Peptides | RNA | Genes | Amyloid beta-protein | Genetic transcription | Monosaccharides | Oligomers | Cell death | Analysis | Physiological aspects | Genetic research | Alzheimer's disease | Sugars | Cell culture | Transcription | Gene regulation | Poly(ADP-ribose) | Cytotoxicity | DNA repair | Mitochondria | Cell activation | Ribose | Inhibition | Deoxyribonucleic acid--DNA | b-Site APP cleaving enzyme 1 | Poly(ADP-ribose) polymerase | Adenosine diphosphate | Data processing | Metabolism | Gene expression | SIRT1 protein | Amyloid precursor protein | Poly(ADP-ribose) Polymerase 1 | Pheochromocytoma cells | β-Amyloid | Secretase | Index Medicus
Journal Article
Experimental & molecular medicine, ISSN 2092-6413, 02/2019, Volume 51, Issue 2, pp. 1 - 18
Journal Article
Molecular medicine reports, ISSN 1791-2997, 08/2015, Volume 12, Issue 2, pp. 3081 - 3088
Journal Article
PloS one, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, pp. e0131199 - e0131199
...) promotes amyloid precursor protein (APP) cleavage by beta-site APP cleaving enzyme 1 (BACE1) without increasing BACE1 levels in APP transgenic mice... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Amyloid Precursor Protein Secretases - genetics | Cricetulus | Humans | Protein Transport - drug effects | Aspartic Acid Endopeptidases - genetics | Mutation, Missense | Obesity - genetics | Alzheimer Disease - pathology | Proteolysis - drug effects | Adaptor Protein Complex 2 - metabolism | Dietary Fats - pharmacology | Amyloid beta-Protein Precursor - metabolism | CHO Cells | Cricetinae | Dietary Fats - adverse effects | Mice, Transgenic | Adaptor Protein Complex 2 - genetics | Protein Transport - genetics | Obesity - metabolism | Obesity - pathology | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Aspartic Acid Endopeptidases - metabolism | Alzheimer Disease - metabolism | Mice | Alzheimer Disease - genetics | Amino Acid Substitution | Health sciences | Clathrin | Complex formation | Cell surface | Risk factors | High fat diet | Proteins | Precursors | Transgenic animals | Rodents | Cleavage | Diabetes mellitus (non-insulin dependent) | Alzheimer's disease | University graduates | Obesity | Medical research | Enzymes | b-Site APP cleaving enzyme 1 | Diabetes mellitus | Transgenic mice | Health risks | Risk analysis | Amyloid precursor protein | Medicine | Neurology | Brain research | Diet | Internalization | Mutation | Alzheimers disease | Dementia | Index Medicus | Trafficking
Journal Article
The New England journal of medicine, ISSN 1533-4406, 05/2018, Volume 378, Issue 18, pp. 1691 - 1703
...) plaques in the brain. A beta is produced from the sequential cleavage of amyloid precursor protein by beta-site amyloid precursor protein-cleaving enzyme 1 (BACE-1... 
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Brain Chemistry - drug effects | Double-Blind Method | Aspartic Acid Endopeptidases - antagonists & inhibitors | Humans | Middle Aged | Alzheimer Disease - drug therapy | Male | Thiadiazines - adverse effects | Cognition - drug effects | Thiadiazines - therapeutic use | Activities of Daily Living | Dose-Response Relationship, Drug | Neuropsychological Tests | Cyclic S-Oxides - therapeutic use | Treatment Failure | Aged, 80 and over | Amyloid beta-Peptides - analysis | Amyloid beta-Peptides - cerebrospinal fluid | Female | Aged | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Biomarkers - cerebrospinal fluid | Alzheimer Disease - psychology | Cyclic S-Oxides - adverse effects | Drugs | Treatment outcome | Usage | Care and treatment | Alzheimer's disease | Analysis | Nuclear magnetic resonance--NMR | Laboratories | Cognitive ability | Clinical trials | Cerebrospinal fluid | Evidence-based medicine | Design | Tomography | Dementia disorders | Plaques | b-Site APP cleaving enzyme 1 | Activities of daily living | Medical imaging | Neurodegenerative diseases | Enrollments | Patients | Amyloid precursor protein | Brain research | Sleep | Biomarkers | b-Site APP cleaving enzyme | Alzheimers disease | Brain injury | Secretase | Dementia | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article