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1. Full Text Cyclosporine-A as a neuroprotective agent against stroke: Its translation from laboratory research to clinical application
by Osman, Mohamed M and Lulic, Dzenan and Glover, Loren and Stahl, Christine E and Lau, Tsz and van Loveren, Harry and Borlongan, Cesar V
Neuropeptides, ISSN 0143-4179, 2011, Volume 45, Issue 6, pp. 359 - 368
Abstract Stoke remains a leading cause of death and disability with limited treatment options. Extensive research has been aimed at studying cell death events... 
Endocrinology & Metabolism | Advanced Basic Science | Immunosuppressant | Neuroprotection | Cerebral ischemia | Mitochondria | Neurological disorders | ADULT RATS | NITRIC-OXIDE SYNTHASE | TRANSIENT FOCAL ISCHEMIA | NEUROSCIENCES | MITOCHONDRIAL PERMEABILITY TRANSITION | CYCLOPHILIN-D | IN-VITRO | TRAUMATIC BRAIN-INJURY | ENDOCRINOLOGY & METABOLISM | BRADYKININ RECEPTOR AGONIST | SPINAL-CORD-INJURY | CEREBRAL-ISCHEMIA | Neuroprotective Agents - therapeutic use | Mitochondrial Membrane Transport Proteins - metabolism | Neuroprotective Agents - chemistry | Brain Injuries - drug therapy | Cyclosporine - pharmacology | Humans | Immunosuppressive Agents - therapeutic use | Treatment Outcome | Clinical Trials as Topic | Stroke - drug therapy | Mitochondria - drug effects | Cyclosporine - therapeutic use | Animals | Neuroprotective Agents - pharmacology | Cyclosporine - chemistry | Molecular Structure | Cell Death - drug effects | Immunosuppressive Agents - pharmacology | Immunosuppressive Agents - chemistry | Stroke (Disease) | Mitochondrial DNA | Permeability | Neurons | Cell death | Immunosuppressive agents
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2. Full Text The Left Atrium: From the Research Laboratory to the Clinic
by Boudoulas, Konstantinos Dean and Paraskevaidis, Ioannis A and Boudoulas, Harisios and Triposkiadis, Filippos K
Cardiology, ISSN 0008-6312, 08/2014, Volume 129, Issue 1, pp. 1 - 17
Studies of left atrial (LA) function, until the latter part of the 20th century, were mostly limited to experimental animal models and to studies related to... 
Turning Basic Research into Clinical Success | Cardiovascular homeostasis | Left ventricle | Left atrium | VENTRICULAR SYSTOLIC DYSFUNCTION | CHRONIC HEART-FAILURE | CARDIAC & CARDIOVASCULAR SYSTEMS | TIME 3-DIMENSIONAL ECHOCARDIOGRAPHY | IDIOPATHIC DILATED CARDIOMYOPATHY | CINE-COMPUTED-TOMOGRAPHY | EXERCISE CAPACITY | NATRIURETIC-PEPTIDES | EJECTION FRACTION | ACUTE MYOCARDIAL-INFARCTION | 2-DIMENSIONAL ECHOCARDIOGRAPHY | Heart Diseases - diagnosis | Atrial Natriuretic Factor - physiology | Heart Atria - pathology | Heart Diseases - etiology | Cardiac Imaging Techniques | Heart Diseases - physiopathology | Humans | Atrial Function, Left - physiology | Atrial Remodeling - physiology | Heart Atria - physiopathology | Heart Atria - metabolism | Clinical trials | Ultrasonic imaging | Cardiology | Medical prognosis | Catheters
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3. Full Text Aortic Function: From the Research Laboratory to the Clinic
by Boudoulas, Konstantinos Dean and Vlachopoulos, Charalambos and Raman, Subha V and Sparks, Elizabeth A and Triposciadis, Filippos and Stefanadis, Christodoulos and Boudoulas, Harisios
Cardiology, ISSN 0008-6312, 03/2012, Volume 121, Issue 1, pp. 31 - 42
For many years, much of the pioneering research on aortic function was carried out by a small group of investigators frequently working away from the clinical... 
Turning Basic Research into Clinical Success | Pulse wave velocity | Reflected waves | Aortic pain | Aortic function | INDEPENDENT PREDICTOR | CARDIAC & CARDIOVASCULAR SYSTEMS | PULSE-WAVE VELOCITY | VASA VASORUM FLOW | ELASTIC PROPERTIES | BLOOD-PRESSURE | PREDICTS CARDIOVASCULAR MORTALITY | ALL-CAUSE MORTALITY | MAGNETIC-RESONANCE | CORONARY-ARTERY-DISEASE | STAGE RENAL-DISEASE | Prognosis | Aorta - anatomy & histology | Humans | Middle Aged | Magnetic Resonance Angiography | Organ Size - physiology | Pressure | Elasticity - physiology | Young Adult | Aortic Diseases - physiopathology | Chest Pain - physiopathology | Chest Pain - etiology | Vascular Stiffness - physiology | Aged, 80 and over | Electrocardiography | Adult | Aged | Aorta - physiology | Aortic Diseases - etiology | Cardiology | Coronary vessels
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4. Full Text P2Y12 Receptor Inhibitors in Acute Coronary Syndromes: From the Research Laboratory to the Clinic and Vice Versa
by Alexopoulos, Dimitrios
Cardiology, ISSN 0008-6312, 03/2014, Volume 127, Issue 4, pp. 211 - 219
The P2Y12 receptor plays a pivotal role in platelet activation and aggregation through a complex cascade of actions. Laboratory and clinical data have... 
Turning Basic Research into Clinical Success | Acute coronary syndrome | Platelet activation | Purinergic P2Y Receptor Antagonists - pharmacology | Ticlopidine - pharmacology | Ticlopidine - therapeutic use | Humans | Treatment Outcome | Clinical Trials as Topic | Diabetic Angiopathies - drug therapy | Renal Insufficiency, Chronic - complications | Ticlopidine - analogs & derivatives | Acute Coronary Syndrome - drug therapy | Acute Coronary Syndrome - complications | Aspirin - therapeutic use | Platelet Activation - drug effects | Platelet Aggregation Inhibitors - therapeutic use | Purinergic P2Y Receptor Antagonists - therapeutic use | Inhibitor drugs | Blood platelets | Acute coronary syndromes | Angioplasty
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5. Scientific integrity
: text and cases in responsible conduct of research
by Macrina, Francis L
2005, 3rd ed., ISBN 9781555813185, xxv, 402
Recherche | Aspect moral | Medical sciences -- Research -- Moral and ethical aspects | Sciences de la santé | Research -- Moral and ethical aspects | Integrity
Book
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6. Science and the quiet art
: the role of medical research in health care
by Weatherall, D. J
1995, 1st ed., ISBN 0393037444, 378
Medicine | Social medicine | Medical sciences | Philosophy
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7. Full Text Evaluation of the implementation of a quality system in a basic research laboratory: viability and impacts
by Fraga, Hilda Carolina de Jesus Rios and Fukutani, Kiyoshi Ferreira and Celes, Fabiana Santana and Barral, Aldina Maria Prado and Oliveira, Camila Indiani de
Einstein (São Paulo, Brazil), ISSN 1679-4508, 2012, Volume 10, Issue 4, pp. 491 - 497
To evaluate the process of implementing a quality management system in a basic research laboratory of a public institution, particularly considering the... 
Laboratories - standards | Prospective Studies | Quality Improvement - organization & administration | Humans | Biomedical Research - organization & administration | Biomedical Research - trends | Program Development - standards | Quality Improvement - trends | Program Evaluation - standards | Surveys and Questionnaires | Research Design | Organizational Case Studies | Quality Control
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8. Scientific integrity : an introductory text with cases
by Macrina, Francis L
2000, 2nd., ISBN 1555811523, xxi, 338 p. ; 26 cm.
Moral and ethical aspects | Research | Medical sciences | Integrity
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9. Full Text Hypoxia protects the liver from Small For Size Syndrome: A lesson learned from the associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure in rats
by Dili, Alexandra and Bertrand, Claude and Lebrun, Valérie and Pirlot, Boris and Leclercq, Isabelle A
American Journal of Transplantation, ISSN 1600-6135, 2019
Portal hyperperfusion and "dearterialization" of the liver remnant are the main pathogenic mechanisms for Small For Size syndrome (SFSS). Associating liver... 
animal models | translational research/science | liver disease | disease pathogenesis | liver transplantation/hepatology | basic (laboratory) research/science
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10. The financing of biomedical research
by Ginzberg, Eli, 1911 and Dutka, Anna B
1989, ISBN 0801838134, x, 144
Financing, Government | Medicine | Finance | Medical sciences | Research | Government policy | trends
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11. The sociology of medical science and technology
by Elston, Mary Ann
1997, Sociology of health and illness monograph series, ISBN 0631204474, 214
Medical technology | Medical sciences | Social aspects | Technology, Medical | Social Medicine
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12. Mathematical models in medical and health science
by Horn, Mary Ann and Simonett, Gieri and Webb, G. F
1998, 1st ed., Innovations in applied mathematics., ISBN 9780826513106, xiv, 396
Medicine | Miscellanea | Mathematical models | Medical sciences | Research
Book
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13. Full Text Runaway powerhouse: Donor mitochondria promote rejection
by Valujskikh, Anna
American Journal of Transplantation, ISSN 1600-6135, 07/2019, Volume 19, Issue 7, pp. 1875 - 1876
This commentary discusses a novel role of mitochondrial DAMPs in allograft rejection reported by Lin et al ( page 1917 ). 
animal models | immunobiology | donors and donation: deceased | basic (laboratory) research/science | SURGERY | basic (laboratory) research | deceased | science | donors and donation | TRANSPLANTATION | Mitochondria | Graft rejection
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14. Full Text Rat Hindlimb Cryopreservation and Transplantation: A Step Toward “Organ Banking”
by Arav, A and Friedman, O and Natan, Y and Gur, E and Shani, N
American Journal of Transplantation, ISSN 1600-6135, 11/2017, Volume 17, Issue 11, pp. 2820 - 2828
In 2016, over 5 million reconstructive procedures were performed in the United States. The recent successes of clinical vascularized composite... 
graft survival | vascularized composite and reconstructive transplantation | basic (laboratory) research/science | organ perfusion and preservation
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15. Full Text Long‐ and short‐term outcomes in renal allografts with deceased donors: A large recipient and donor genome‐wide association study
by Hernandez‐Fuentes, Maria P and Franklin, Christopher and Rebollo‐Mesa, Irene and Mollon, Jennifer and Delaney, Florence and Perucha, Esperanza and Stapleton, Caragh and Borrows, Richard and Byrne, Catherine and Cavalleri, Gianpiero and Clarke, Brendan and Clatworthy, Menna and Feehally, John and Fuggle, Susan and Gagliano, Sarah A and Griffin, Sian and Hammad, Abdul and Higgins, Robert and Jardine, Alan and Keogan, Mary and Leach, Timothy and MacPhee, Iain and Mark, Patrick B and Marsh, James and Maxwell, Peter and McKane, William and McLean, Adam and Newstead, Charles and Augustine, Titus and Phelan, Paul and Powis, Steve and Rowe, Peter and Sheerin, Neil and Solomon, Ellen and Stephens, Henry and Thuraisingham, Raj and Trembath, Richard and Topham, Peter and Vaughan, Robert and Sacks, Steven H and Conlon, Peter and Opelz, Gerhard and Soranzo, Nicole and Weale, Michael E and Lord, Graham M and Wellcome Trust Case Control and UKIRTC and United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3 and the United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3
American Journal of Transplantation, ISSN 1600-6135, 06/2018, Volume 18, Issue 6, pp. 1370 - 1379
Improvements in immunosuppression have modified short‐term survival of deceased‐donor allografts, but not their rate of long‐term failure. Mismatches between... 
graft survival | genomics | translational research/science | kidney transplantation/nephrology | rejection | basic (laboratory) research/science | SURGERY | basic (laboratory) research | kidney transplantation | RISK | FAILURE | TRANSPLANTATION | nephrology | POLYMORPHISMS | GENE | KIDNEY-TRANSPLANTATION | DECADE | science | DISEASE | translational research | IDENTICAL-TWINS | AFRICAN-AMERICANS | Kidneys | Analysis | Immunotherapy | Genomics | Homografts | Genetic research | Transplantation | ORIGINAL ARTICLES | Original
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16. Full Text Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC‐Specific Chimeric Antigen Receptor
by Noyan, F and Zimmermann, K and Hardtke‐Wolenski, M and Knoefel, A and Schulde, E and Geffers, R and Hust, M and Huehn, J and Galla, M and Morgan, M and Jokuszies, A and Manns, M. P and Jaeckel, E
American Journal of Transplantation, ISSN 1600-6135, 04/2017, Volume 17, Issue 4, pp. 917 - 930
CD 4 + CD 25 high FOXP 3 + regulatory T cells (Tregs) are involved in graft‐specific tolerance after solid organ transplantation. However, adoptive transfer of... 
translational research/science | immunosuppression/immune modulation | T cell biology | tissue (nonvascularized) transplantation | gene therapy | immunobiology | tolerance: experimental | tolerance | basic (laboratory) research/science | SURGERY | basic (laboratory) research | LIVER-TRANSPLANTATION | INSTABILITY | immunosuppression | TRANSPLANTATION | THERAPY | TRANSPLANTATION TOLERANCE | science | IN-VIVO | FREQUENCY | DISEASE | ENRICHMENT | translational research | GENERATION | immune modulation | Graft Survival - immunology | HLA-A2 Antigen - immunology | Graft Rejection - prevention & control | Humans | Receptors, Interleukin-2 - immunology | T-Lymphocytes, Regulatory - immunology | Allografts | Animals | Mice, Inbred NOD | Receptors, Antigen, T-Cell - immunology | Mice | Graft Rejection - immunology | Transplantation Tolerance - immunology | Antigens | Epigenetic inheritance | Immunotherapy | Transplantation of organs, tissues, etc | T cells | Cells | Graft rejection | Lymphocytes | T cell receptors
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