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1. Full Text Hypoxia protects the liver from Small For Size Syndrome: A lesson learned from the associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure in rats
by Dili, Alexandra and Bertrand, Claude and Lebrun, Valérie and Pirlot, Boris and Leclercq, Isabelle A
American Journal of Transplantation, ISSN 1600-6135, 2019
Portal hyperperfusion and "dearterialization" of the liver remnant are the main pathogenic mechanisms for Small For Size syndrome (SFSS). Associating liver... 
animal models | translational research/science | liver disease | disease pathogenesis | liver transplantation/hepatology | basic (laboratory) research/science
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2. Full Text Rat Hindlimb Cryopreservation and Transplantation: A Step Toward “Organ Banking”
by Arav, A and Friedman, O and Natan, Y and Gur, E and Shani, N
American Journal of Transplantation, ISSN 1600-6135, 11/2017, Volume 17, Issue 11, pp. 2820 - 2828
In 2016, over 5 million reconstructive procedures were performed in the United States. The recent successes of clinical vascularized composite... 
graft survival | vascularized composite and reconstructive transplantation | basic (laboratory) research/science | organ perfusion and preservation
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3. Full Text C5aR1 governs Mreg migration, development, and function
by Riquelme, Paloma and Geissler, Edward K and Hutchinson, James A
American Journal of Transplantation, ISSN 1600-6135, 03/2019, Volume 19, Issue 3, pp. 619 - 621
This editorial connects the basic science findings from the article by Llaudo et al ( page 633 ) with their clinical potential. 
complement biology | editorial/personal viewpoint | immunobiology | macrophage/monocyte biology | basic (laboratory) research/science | SURGERY | MONOCYTES | TRANSPLANTATION | Migration
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4. Full Text Runaway powerhouse: Donor mitochondria promote rejection
by Valujskikh, Anna
American Journal of Transplantation, ISSN 1600-6135, 07/2019, Volume 19, Issue 7, pp. 1875 - 1876
This commentary discusses a novel role of mitochondrial DAMPs in allograft rejection reported by Lin et al ( page 1917 ). 
animal models | immunobiology | donors and donation: deceased | basic (laboratory) research/science | SURGERY | basic (laboratory) research | deceased | science | donors and donation | TRANSPLANTATION | Mitochondria | Graft rejection
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5. Full Text Reply to “Representing Subnormothermic Machine Perfusion in Fatty Livers: The Complete Picture?”
by Okamura, Y and Hata, K and Uemoto, S
American Journal of Transplantation, ISSN 1600-6135, 05/2017, Volume 17, Issue 5, pp. 1423 - 1424
animal models: murine | liver transplantation/hepatology | basic (laboratory) research/science | organ perfusion and preservation
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6. Full Text Optimization and Critical Evaluation of Decellularization Strategies to Develop Renal Extracellular Matrix Scaffolds as Biological Templates for Organ Engineering and Transplantation
by Caralt, M and Uzarski, J. S and Iacob, S and Obergfell, K. P and Berg, N and Bijonowski, B. M and Kiefer, K. M and Ward, H. H and Wandinger‐Ness, A and Miller, W. M and Zhang, Z. J and Abecassis, M. M and Wertheim, J. A
American Journal of Transplantation, ISSN 1600-6135, 01/2015, Volume 15, Issue 1, pp. 64 - 75
The authors validate an optimal detergent‐based protocol for decellularization of rodent whole‐kidney scaffolds, showing that decellularized scaffolds retain... 
regenerative medicine | animal models: murine, bioengineering, kidney biology, stem cells | basic (laboratory) research/science | tissue/organ engineering | SURGERY | stem cells | basic (laboratory) research | ORTHOTOPIC TRANSPLANTATION | STEM-CELLS | organ engineering | RECELLULARIZATION | PORCINE KIDNEYS | COMPONENTS | kidney biology | tissue | KIDNEY REGENERATION | bioengineering | TRANSPLANTATION | HEART | PLATFORM | animal models: murine | IMPLANTATION | science | Endothelium, Vascular - cytology | Detergents - pharmacology | Kidney Tubules - drug effects | Humans | Kidney Tubules - physiology | Cells, Cultured | Rats | Male | Organ Transplantation - standards | Kidney Tubules - blood supply | Rats, Sprague-Dawley | Tissue Scaffolds | Animals | Perfusion | Extracellular Matrix - physiology | Cell Differentiation | Induced Pluripotent Stem Cells - cytology | Tissue Engineering | Surface active agents | Endothelial growth factors | Analysis | Stem cells | Fibroblast growth factors | Cell differentiation | Sulfates | Bioengineering | Extracellular matrix | Kidneys | Rodents | Optimization | Index Medicus
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7. Full Text Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC‐Specific Chimeric Antigen Receptor
by Noyan, F and Zimmermann, K and Hardtke‐Wolenski, M and Knoefel, A and Schulde, E and Geffers, R and Hust, M and Huehn, J and Galla, M and Morgan, M and Jokuszies, A and Manns, M. P and Jaeckel, E
American Journal of Transplantation, ISSN 1600-6135, 04/2017, Volume 17, Issue 4, pp. 917 - 930
CD 4 + CD 25 high FOXP 3 + regulatory T cells (Tregs) are involved in graft‐specific tolerance after solid organ transplantation. However, adoptive transfer of... 
translational research/science | immunosuppression/immune modulation | T cell biology | tissue (nonvascularized) transplantation | gene therapy | immunobiology | tolerance: experimental | tolerance | basic (laboratory) research/science | SURGERY | basic (laboratory) research | LIVER-TRANSPLANTATION | INSTABILITY | immunosuppression | TRANSPLANTATION | THERAPY | TRANSPLANTATION TOLERANCE | science | IN-VIVO | FREQUENCY | DISEASE | ENRICHMENT | translational research | GENERATION | immune modulation | Graft Survival - immunology | HLA-A2 Antigen - immunology | Graft Rejection - prevention & control | Humans | Receptors, Interleukin-2 - immunology | T-Lymphocytes, Regulatory - immunology | Allografts | Animals | Mice, Inbred NOD | Receptors, Antigen, T-Cell - immunology | Mice | Graft Rejection - immunology | Transplantation Tolerance - immunology | Antigens | Epigenetic inheritance | Immunotherapy | Transplantation of organs, tissues, etc | T cells | Cells | Graft rejection | Lymphocytes | T cell receptors | Index Medicus
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8. Full Text Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection
by Boardman, D. A and Philippeos, C and Fruhwirth, G. O and Ibrahim, M. A. A and Hannen, R. F and Cooper, D and Marelli‐Berg, F. M and Watt, F. M and Lechler, R. I and Maher, J and Smyth, L. A and Lombardi, G
American Journal of Transplantation, ISSN 1600-6135, 04/2017, Volume 17, Issue 4, pp. 931 - 943
Regulatory T cell (Treg) therapy using recipient‐derived Tregs expanded ex vivo is currently being investigated clinically by us and others as a means of... 
molecular biology | animal models: murine | translational research/science | immunosuppression/immune modulation | T cell biology | cellular biology | gene therapy | alloantigen | immune regulation | basic (laboratory) research/science | SURVIVAL | SURGERY | basic (laboratory) research | INDIRECT ALLOSPECIFICITY | TOLERANCE | CHRONIC ALLOGRAFT-REJECTION | immunosuppression | PROLIFERATION | SUPPRESSION | TRANSPLANTATION | COLITIS | IMMUNOTHERAPY | science | EXPANSION | CD28 | translational research | immune modulation | Graft Survival - immunology | HLA-A2 Antigen - immunology | Receptors, Antigen - immunology | Graft Rejection - prevention & control | Humans | Graft Rejection - etiology | Leukocytes, Mononuclear | Skin Transplantation - adverse effects | T-Lymphocytes, Regulatory - immunology | Allografts | Animals | Heterografts | Mice | Mice, Inbred BALB C | Transplantation Tolerance - immunology | Proteins | Histocompatibility antigens | HLA histocompatibility antigens | Transplantation of organs, tissues, etc | Used cars | Skin | Molecular biology | T cells | Cells | Graft rejection | Index Medicus
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9. Full Text Long‐ and short‐term outcomes in renal allografts with deceased donors: A large recipient and donor genome‐wide association study
by Hernandez‐Fuentes, Maria P and Franklin, Christopher and Rebollo‐Mesa, Irene and Mollon, Jennifer and Delaney, Florence and Perucha, Esperanza and Stapleton, Caragh and Borrows, Richard and Byrne, Catherine and Cavalleri, Gianpiero and Clarke, Brendan and Clatworthy, Menna and Feehally, John and Fuggle, Susan and Gagliano, Sarah A and Griffin, Sian and Hammad, Abdul and Higgins, Robert and Jardine, Alan and Keogan, Mary and Leach, Timothy and MacPhee, Iain and Mark, Patrick B and Marsh, James and Maxwell, Peter and McKane, William and McLean, Adam and Newstead, Charles and Augustine, Titus and Phelan, Paul and Powis, Steve and Rowe, Peter and Sheerin, Neil and Solomon, Ellen and Stephens, Henry and Thuraisingham, Raj and Trembath, Richard and Topham, Peter and Vaughan, Robert and Sacks, Steven H and Conlon, Peter and Opelz, Gerhard and Soranzo, Nicole and Weale, Michael E and Lord, Graham M and Wellcome Trust Case Control and UKIRTC and United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3 and the United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3
American Journal of Transplantation, ISSN 1600-6135, 06/2018, Volume 18, Issue 6, pp. 1370 - 1379
Improvements in immunosuppression have modified short‐term survival of deceased‐donor allografts, but not their rate of long‐term failure. Mismatches between... 
graft survival | genomics | translational research/science | kidney transplantation/nephrology | rejection | basic (laboratory) research/science | SURGERY | basic (laboratory) research | kidney transplantation | RISK | FAILURE | TRANSPLANTATION | nephrology | POLYMORPHISMS | GENE | KIDNEY-TRANSPLANTATION | DECADE | science | DISEASE | translational research | IDENTICAL-TWINS | AFRICAN-AMERICANS | Kidneys | Analysis | Immunotherapy | Genomics | Homografts | Genetic research | Transplantation | ORIGINAL ARTICLES | Original
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10. Full Text Towards donor lung recovery—gene expression changes during ex vivo lung perfusion of human lungs
by Yeung, Jonathan C and Zamel, Ricardo and Klement, William and Bai, Xiao‐Hui and Machuca, Tiago N and Waddell, Thomas K and Liu, Mingyao and Cypel, Marcelo and Keshavjee, Shaf
American Journal of Transplantation, ISSN 1600-6135, 06/2018, Volume 18, Issue 6, pp. 1518 - 1526
We and others have demonstrated that acellular normothermic ex vivo lung perfusion of high‐risk donor lungs can result in posttransplant outcomes equivalent to... 
molecular biology | expression | organ acceptance | translational research/science | lung transplantation/pulmonology | mRNA | basic (laboratory) research/science | organ perfusion and preservation | molecular biology: mRNA/mRNA expression | Genetic research | Transplantation of organs, tissues, etc | Gene expression | Analysis | Genes
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11. Full Text Disruption of Transplant Tolerance by an “Incognito” Form of CD8 T Cell–Dependent Memory
by Nelsen, M. K and Beard, K. S and Plenter, R. J and Kedl, R. M and Clambey, E. T and Gill, R. G
American Journal of Transplantation, ISSN 1600-6135, 07/2017, Volume 17, Issue 7, pp. 1742 - 1753
Several approaches successfully achieve allograft tolerance in preclinical models but are challenging to translate into clinical practice. Many clinically... 
tolerance: costimulation blockade | T cell biology | islet transplantation | immunobiology | tolerance | immune regulation | basic (laboratory) research/science
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12. Full Text Alginate Encapsulant Incorporating CXCL12 Supports Long‐Term Allo‐ and Xenoislet Transplantation Without Systemic Immune Suppression
by Chen, T and Yuan, J and Duncanson, S and Hibert, M. L and Kodish, B. C and Mylavaganam, G and Maker, M and Li, H and Sremac, M and Santosuosso, M and Forbes, B and Kashiwagi, S and Cao, J and Lei, J and Thomas, M and Hartono, C and Sachs, D and Markmann, J and Sambanis, A and Poznansky, M. C
American Journal of Transplantation, ISSN 1600-6135, 03/2015, Volume 15, Issue 3, pp. 618 - 627
An alginate microencapsulant incorporating CXCL12 acts as a T cell chemorepellent and an islet prosurvival factor that supports long‐term allo‐ and xenoislet... 
kidney biology | animal models | xenotransplantation | kidney transplantation/nephrology | basic (laboratory) research/science | SURVIVAL | SURGERY | basic (laboratory) research | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | NOD MICE | ACTIVE MOVEMENT | kidney transplantation | BONE-MARROW | MESENCHYMAL STEM-CELLS | TRANSPLANTATION | nephrology | ISLET TRANSPLANTATION | DIABETES-MELLITUS | PANCREATIC-ISLETS | science | REGULATORY T-CELLS | Islets of Langerhans Transplantation - immunology | Alginates - administration & dosage | Animals | Heterografts | Hexuronic Acids - administration & dosage | Female | Mice | Mice, Inbred BALB C | Glucuronic Acid - administration & dosage | Chemokine CXCL12 - administration & dosage | Transplantation, Homologous | Chemokines | Diabetes | Index Medicus
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13. Full Text Liver Preservation With Machine Perfusion and a Newly Developed Cell‐Free Oxygen Carrier Solution Under Subnormothermic Conditions
by Fontes, P and Lopez, R and van der Plaats, A and Vodovotz, Y and Minervini, M and Scott, V and Soltys, K and Shiva, S and Paranjpe, S and Sadowsky, D and Barclay, D and Zamora, R and Stolz, D and Demetris, A and Michalopoulos, G and Marsh, J. W
American Journal of Transplantation, ISSN 1600-6135, 02/2015, Volume 15, Issue 2, pp. 381 - 394
The authors compare machine perfusion with a cell‐free oxygen carrier solution at 21°C with cold storage preservation in a porcine liver transplant model and... 
pathology/histopathology | metabolomics | regenerative medicine | donors and donation: donation after circulatory death (DCD) | ischemia reperfusion injury (IRI) | liver transplantation/hepatology | animal models: porcine | basic (laboratory) research/science | organ perfusion and preservation | HEMOGLOBIN | SURVIVAL | SURGERY | LOW-FLOW | DONATION | INJURY | SUBSTITUTES | CARDIAC DEATH | ISCHEMIA-REPERFUSION | REGULATORY FACTOR-I | TRANSPLANTATION | Metabolomics | Cold Temperature | Oxygen | Perfusion - instrumentation | Organ Preservation - methods | Gene Expression Profiling | Liver Transplantation - methods | Perfusion - methods | Allografts | Animals | Graft Survival - physiology | Liver - physiology | Organ Preservation Solutions | Sus scrofa | Hemoglobins | Hemoglobin | Lactates | Urea | Biological response modifiers | Liver | Index Medicus | basic (laboratory) research | pathology | hepatology | histopathology | science | Original | liver transplantation
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