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Molecular cell, ISSN 1097-2765, 11/2009, Volume 36, Issue 3, pp. 487 - 499
.... BAK, an integral mitochondrial membrane protein, has bypassed the first activation step, explaining why its killing kinetics are faster than those of... 
CELLCYCLE | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | bcl-2-Associated X Protein - chemistry | Immunoprecipitation | Apoptosis - drug effects | Protein Multimerization | bcl-2 Homologous Antagonist-Killer Protein - genetics | Immunoblotting | BH3 Interacting Domain Death Agonist Protein - genetics | Green Fluorescent Proteins - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Bcl-2-Like Protein 11 | Protein Binding - drug effects | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Fibroblasts - metabolism | Proto-Oncogene Proteins - metabolism | Green Fluorescent Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Etoposide - pharmacology | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Models, Biological | Tunicamycin - pharmacology | Fibroblasts - drug effects | Thapsigargin - pharmacology | Fibroblasts - cytology | Mice | Mutation | Microscopy, Fluorescence | Staurosporine - pharmacology | bcl-2 Homologous Antagonist-Killer Protein - chemistry | Monomers | Apoptosis | Oligomers | Index Medicus
Journal Article
Nature cell biology, ISSN 1476-4679, 09/2015, Volume 17, Issue 10, pp. 1270 - 1281
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 07/2011, Volume 30, Issue 14, pp. 2779 - 2792
...‐apoptotic proteins belonging to the BCL‐2 family, each characteristically possessing a BCL... 
MOMP | ageing | BH3 domain | yeast | mitochondrial apoptosis | Ageing | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Immunoprecipitation | Saccharomyces cerevisiae - genetics | Humans | Lung Neoplasms - metabolism | Phosphate Transport Proteins - metabolism | bcl-X Protein - genetics | Molecular Sequence Data | Peptide Fragments - pharmacology | Mitochondrial Proteins - genetics | Bone Neoplasms - metabolism | Saccharomyces cerevisiae - metabolism | Flow Cytometry | Mitochondria - genetics | Mitochondrial Proteins - metabolism | Membrane Potential, Mitochondrial | Apoptosis Regulatory Proteins - genetics | Bone Neoplasms - genetics | Tumor Cells, Cultured | Phosphate Transport Proteins - genetics | bcl-2-Associated X Protein - genetics | Lung Neoplasms - genetics | Proto-Oncogene Proteins - pharmacology | Amino Acid Sequence | Signal Transduction | Saccharomyces cerevisiae Proteins - antagonists & inhibitors | RNA, Messenger - genetics | bcl-2-Associated X Protein - metabolism | Mitochondria - metabolism | Saccharomyces cerevisiae Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Sequence Homology, Amino Acid | Animals | Cell Cycle | Apoptosis Regulatory Proteins - antagonists & inhibitors | Saccharomyces cerevisiae Proteins - metabolism | Mice | bcl-X Protein - metabolism | Apoptosis | Proteins | Mitochondria | Yeast | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 12/2007, Volume 282, Issue 50, pp. 36177 - 36189
As a multifunctional protein, KRAB domain-associated protein 1 (KAP1) is reportedly subjected to multiple protein posttranslational modifications, including phosphorylation and sumoylation... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Transcription, Genetic - drug effects | Antibiotics, Antineoplastic - pharmacology | Apoptosis - drug effects | Humans | bcl-2-Associated X Protein - biosynthesis | Mutation, Missense | Proto-Oncogene Proteins - biosynthesis | Tripartite Motif-Containing Protein 28 | DNA-Binding Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | DNA Damage - physiology | SUMO-1 Protein - genetics | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Cell Cycle Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Phosphorylation - drug effects | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Repressor Proteins - metabolism | bcl-2-Associated X Protein - genetics | Apoptosis Regulatory Proteins - biosynthesis | DNA Damage - drug effects | Cell Line | Cysteine Endopeptidases | Endopeptidases - metabolism | Tumor Suppressor Proteins - metabolism | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Repressor Proteins - genetics | Serine - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Serine - metabolism | Transcription, Genetic - physiology | Endopeptidases - genetics | Cell Cycle - physiology | SUMO-1 Protein - metabolism | Apoptosis - physiology | Cell Cycle - drug effects | Proto-Oncogene Proteins c-bcl-2 - genetics | Doxorubicin - pharmacology | Index Medicus
Journal Article
Journal of leukocyte biology, ISSN 0741-5400, 02/2015, Volume 97, Issue 2, pp. 425 - 433
...Abbreviations ATF6 activating transcription factor 6 Atg autophagy‐related gene Bax B cell lymphoma‐associated protein Bcl B cell lymphoma BiP binding Ig... 
T cells | apoptosis | SLE | Immunology | Life Sciences & Biomedicine | Hematology | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Transcription Factor CHOP - genetics | Endoribonucleases - genetics | Activating Transcription Factor 6 - immunology | Humans | bcl-X Protein - genetics | eIF-2 Kinase - immunology | Male | Endoplasmic Reticulum Stress - genetics | Activating Transcription Factor 6 - genetics | Endoplasmic Reticulum Stress - immunology | Autophagy - immunology | Heat-Shock Proteins - genetics | RNA, Small Interfering - immunology | Lupus Erythematosus, Systemic - immunology | Transcription Factor CHOP - immunology | bcl-X Protein - immunology | Apoptosis Regulatory Proteins - genetics | Female | Autophagy - genetics | T-Lymphocytes - pathology | bcl-2-Associated X Protein - genetics | eIF-2 Kinase - genetics | Beclin-1 | Apoptosis Regulatory Proteins - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Membrane Proteins - genetics | Protein-Serine-Threonine Kinases - genetics | Membrane Proteins - immunology | Heat-Shock Proteins - immunology | bcl-2-Associated X Protein - immunology | Caspase 6 - genetics | Eukaryotic Initiation Factor-2 - genetics | Lupus Erythematosus, Systemic - genetics | Protein-Serine-Threonine Kinases - immunology | T-Lymphocytes - immunology | Caspase 6 - immunology | Eukaryotic Initiation Factor-2 - immunology | Lupus Erythematosus, Systemic - pathology | Endoribonucleases - immunology | Index Medicus
Journal Article
Scientific reports, ISSN 2045-2322, 07/2017, Volume 7, Issue 1, pp. 4795 - 13
Doxorubicin (DOX) is the mainstay chemotherapeutic agent against a variety of human neoplasmas. However, its clinical utility is limited by its marked... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Apoptosis - drug effects | Caspase 3 - metabolism | Cardiomyopathies - prevention & control | Male | NF-kappa B - metabolism | Cytochromes c - genetics | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Cardiomyopathies - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspase 3 - genetics | Apoptosis Regulatory Proteins - genetics | Flavonoids - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Proto-Oncogene Proteins c-akt - metabolism | bcl-2-Associated X Protein - genetics | Cardiotoxicity - prevention & control | Drug Administration Schedule | Signal Transduction | Cytochromes c - metabolism | Tumor Suppressor Protein p53 - metabolism | bcl-2-Associated X Protein - metabolism | Rats | p38 Mitogen-Activated Protein Kinases - genetics | Cardiomyopathies - pathology | Antioxidants - pharmacology | Cardiotonic Agents - pharmacology | Rats, Sprague-Dawley | Doxorubicin - toxicity | Apoptosis Regulatory Proteins - metabolism | Gene Expression Regulation - drug effects | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | NF-kappa B - genetics | Myocytes, Cardiac - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Cardiomyopathies - chemically induced | Oxidative stress | NF-κB protein | Conduction | Bax protein | Bcl-2 protein | Cardiomyopathy | p53 Protein | Lipid peroxidation | Caspase | MAP kinase | JNK protein | AKT protein | Inflammation | Caspase-3 | Doxorubicin | Cytochrome c | Antioxidants | Molecular modelling | Rodents | Vascular endothelial growth factor | PTEN protein | Apoptosis | Cancer | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 3, pp. e18330 - e18330
... of functional dependence on Bid/Bim and Bax/Bak, proapoptotic components of the mitochondrial pathway. Hedgehog signaling modulated expression of X-linked inhibitor of apoptosis... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Humans | Zinc Finger Protein Gli2 | bcl-2 Homologous Antagonist-Killer Protein - genetics | Hedgehog Proteins - metabolism | Immunoblotting | BH3 Interacting Domain Death Agonist Protein - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Promoter Regions, Genetic - genetics | TNF-Related Apoptosis-Inducing Ligand - pharmacology | Bcl-2-Like Protein 11 | Chromatin Immunoprecipitation | Hedgehog Proteins - genetics | RNA Interference | Kruppel-Like Transcription Factors - metabolism | Veratrum Alkaloids - pharmacology | Apoptosis Regulatory Proteins - genetics | Electrophoretic Mobility Shift Assay | Inhibitor of Apoptosis Proteins - metabolism | Membrane Proteins - metabolism | Nuclear Proteins - genetics | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Proto-Oncogene Proteins - metabolism | Cell Line | Membrane Proteins - genetics | bcl-2-Associated X Protein - metabolism | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | X-Linked Inhibitor of Apoptosis Protein - genetics | Apoptosis Regulatory Proteins - metabolism | Transcription Factors - metabolism | Signal Transduction - drug effects | X-Linked Inhibitor of Apoptosis Protein - metabolism | Cell Line, Tumor | Zinc Finger Protein GLI1 | Kruppel-Like Transcription Factors - genetics | Biochemistry | Cell death | Health aspects | Analysis | Cancer cells | Cancer | Bax protein | Toxicity | Cytotoxicity | XIAP protein | Metastasis | Neoplasms | Proteins | Signal transduction | Hepatitis | Mitochondria | Hepatology | Gastroenterology | Tumor necrosis factor-TNF | Inhibition | Cholangiocarcinoma | Immunoglobulins | Mortality | Pharmacology | siRNA | Chemical compounds | Signaling | Glioma | Hedgehog protein | Pancreatic cancer | Ligands | BIM protein | Apoptosis | Tumors | Index Medicus
Journal Article