X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (858) 858
animals (621) 621
apoptosis (621) 621
humans (460) 460
mice (449) 449
bcl-x protein (340) 340
cell biology (268) 268
bcl-x protein - metabolism (244) 244
apoptosis - drug effects (218) 218
biochemistry & molecular biology (201) 201
bcl-x (193) 193
proteins (192) 192
proto-oncogene proteins c-bcl-2 - metabolism (192) 192
bcl-x-l (190) 190
mice, knockout (185) 185
apoptosis - physiology (159) 159
signal transduction (159) 159
expression (153) 153
male (151) 151
mitochondria (150) 150
bcl-x protein - genetics (147) 147
proto-oncogene proteins c-bcl-2 - genetics (146) 146
oncology (143) 143
activation (141) 141
cells, cultured (138) 138
cell death (137) 137
female (137) 137
immunology (136) 136
cancer (134) 134
mice, inbred c57bl (122) 122
bcl-2 (115) 115
gene expression (114) 114
cell survival (113) 113
cell-death (113) 113
cell line, tumor (112) 112
bax (109) 109
mitochondria - metabolism (108) 108
in-vivo (107) 107
death (105) 105
caspases - metabolism (104) 104
apoptosis - genetics (99) 99
rats (96) 96
neurosciences (92) 92
phosphorylation (89) 89
medicine (85) 85
research article (85) 85
survival (84) 84
article (83) 83
abridged index medicus (80) 80
kinases (79) 79
multidisciplinary sciences (79) 79
research (78) 78
autophagy (77) 77
bcl-2 protein (77) 77
bcl-2-associated x protein (77) 77
mice, transgenic (77) 77
oxidative stress (73) 73
science (73) 73
cell line (72) 72
rodents (71) 71
proto-oncogene proteins - metabolism (70) 70
bcl-xl (69) 69
nf-kappa-b (69) 69
bcl-2-associated x protein - metabolism (66) 66
cell proliferation (66) 66
cytochrome-c (65) 65
biology (64) 64
cytochrome-c release (64) 64
caspase (63) 63
signal transduction - drug effects (63) 63
proto-oncogene proteins - genetics (62) 62
cell survival - drug effects (60) 60
protein (59) 59
cell cycle (58) 58
cells (58) 58
blotting, western (57) 57
gene-expression (57) 57
proto-oncogene proteins c-bcl-2 - biosynthesis (57) 57
analysis (55) 55
apoptosis regulatory proteins - metabolism (55) 55
bax protein (55) 55
gene (55) 55
proto-oncogene proteins c-bcl-2 - physiology (55) 55
biochemistry (53) 53
p53 (53) 53
health aspects (51) 51
transfection (51) 51
cytochrome c (50) 50
hematology (50) 50
in-vitro (50) 50
disease models, animal (49) 49
tumor suppressor protein p53 - metabolism (49) 49
up-regulation (49) 49
membrane proteins - metabolism (48) 48
gene expression regulation (47) 47
caspase-3 (46) 46
tumors (46) 46
caspase 3 (45) 45
cytochromes c - metabolism (45) 45
induced apoptosis (45) 45
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, pp. 6377 - 6377
Tyrosine kinase inhibitors are effective treatments for non-small-cell lung cancers (NSCLCs) with epidermal growth factor receptor (EGFR) mutations. However,... 
GROWTH-FACTOR RECEPTOR | DRUG-SENSITIVITY | GEFITINIB | AMPLIFICATION | MODELS | GENE | MULTIDISCIPLINARY SCIENCES | MUTATION | ACQUIRED-RESISTANCE | KINASE INHIBITORS | CHEMOTHERAPY | Lung Neoplasms - drug therapy | Recurrence | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Humans | Lung Neoplasms - metabolism | ErbB Receptors - genetics | Gene Expression Regulation, Neoplastic | bcl-X Protein - genetics | Lung Neoplasms - pathology | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Adenocarcinoma - metabolism | Adenocarcinoma - genetics | Antineoplastic Agents - pharmacology | Lung - metabolism | Gefitinib | ErbB Receptors - deficiency | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung - pathology | Aniline Compounds - pharmacology | ErbB Receptors - antagonists & inhibitors | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Retinoblastoma Protein - deficiency | Small Cell Lung Carcinoma - genetics | Sulfonamides - pharmacology | Adenocarcinoma - drug therapy | Disease Progression | Drug Resistance, Neoplasm - genetics | Small Cell Lung Carcinoma - pathology | Afatinib | Retinoblastoma Protein - genetics | Erlotinib Hydrochloride - pharmacology | Lung - drug effects | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Quinazolines - pharmacology | bcl-X Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Drug Resistance, Neoplasm - drug effects | Index Medicus
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 57, Issue 1, pp. 92 - 100
Journal Article
Cell death & disease, ISSN 2041-4889, 06/2016, Volume 7, Issue 6, pp. e2266 - e2266
How BH3-only proteins activate Bax/Bak, the two gateway proteins of the mitochondria-dependent apoptotic pathway, remains incompletely understood. Although all... 
PROSURVIVAL BCL-2 PROTEINS | APOPTOTIC PORE | X-L | MCL-1 | MITOCHONDRIA | BAX | BH3 DOMAINS | BCL-X(L) | CELL-DEATH | REVEALS | CELL BIOLOGY | BH3 Interacting Domain Death Agonist Protein - deficiency | RNA, Small Interfering - antagonists & inhibitors | RNA, Small Interfering - genetics | Humans | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | bcl-2 Homologous Antagonist-Killer Protein - genetics | bcl-X Protein - genetics | BH3 Interacting Domain Death Agonist Protein - genetics | Green Fluorescent Proteins - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Recombinant Fusion Proteins - metabolism | Tumor Suppressor Protein p53 - genetics | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | Apoptosis Regulatory Proteins - deficiency | bcl-X Protein - antagonists & inhibitors | Apoptosis Regulatory Proteins - genetics | Genes, Reporter | bcl-2-Associated X Protein - genetics | Green Fluorescent Proteins - metabolism | Myeloid Cell Leukemia Sequence 1 Protein - antagonists & inhibitors | Signal Transduction | HCT116 Cells | Gene Expression Regulation | bcl-2-Associated X Protein - metabolism | Proto-Oncogene Proteins - genetics | Bcl-2-Like Protein 11 - genetics | Mitochondria - metabolism | Proto-Oncogene Proteins - deficiency | Gene Knockout Techniques | Sulfonamides - pharmacology | Tumor Suppressor Protein p53 - deficiency | Piperazines - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Recombinant Fusion Proteins - genetics | Bcl-2-Like Protein 11 - deficiency | bcl-X Protein - metabolism | Apoptosis | RNA, Small Interfering - metabolism | Index Medicus | Original
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2013, Volume 56, Issue 13, pp. 5514 - 5540
Journal Article
Cell Death and Disease, ISSN 2041-4889, 07/2017, Volume 8, Issue 7, pp. e2914 - e2914
Anaemia is a major global health problem arising from diverse causes and for which improved therapeutic strategies are needed. Erythroid cells can undergo... 
ERYTHROPOIETIN | MEDICAL PROGRESS | MITOCHONDRIAL | HEMATOPOIETIC STEM-CELLS | IN-VIVO | DEATH | DEFICIENT MICE | ANTITUMOR-ACTIVITY | INHIBITOR | FAMILY | CELL BIOLOGY | Humans | Erythroblasts - metabolism | bcl-X Protein - genetics | Anemia - pathology | Apoptosis - genetics | bcl-X Protein - deficiency | Anemia - genetics | Isoquinolines - pharmacology | Apoptosis Regulatory Proteins - deficiency | Tumor Suppressor Proteins - deficiency | bcl-X Protein - antagonists & inhibitors | Gene Deletion | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Protein Domains | Reticulocytes - pathology | Disease Models, Animal | Erythropoiesis - genetics | Signal Transduction | Benzothiazoles - pharmacology | Cell Survival | Gene Expression Regulation | Bcl-2-Like Protein 11 - genetics | Organ Specificity | Reticulocytes - metabolism | Mice, Knockout | Anemia - metabolism | Animals | Tamoxifen - pharmacology | Bcl-2-Like Protein 11 - deficiency | Mice | Erythroblasts - pathology | Erythropoiesis | Cell survival | Anemia | Erythrocytes | Reticulocytes | Antagonists | Tamoxifen | Gene deletion | Erythroid cells | Survival | Bcl-x protein | Clonal deletion | Developmental stages | Erythroblasts | Cell death | Bcl protein | Bone marrow | Protein expression | BIM protein | Apoptosis | Index Medicus | Original
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2017, Volume 19, Issue 10, pp. 1226 - 1236
Direct interactions between pro-and anti-apoptotic BCL-2 family members form the basis of cell death decision-making at the outer mitochondrial membrane (OMM).... 
SIGNAL | APOPTOSIS | ACTIVATION | SONIC HEDGEHOG | PATHWAY | MCL-1 | GENOMIC ANALYSIS | RESISTANCE | PROLIFERATION | MEDULLOBLASTOMA | CELL BIOLOGY | Neoplasms - metabolism | NIH 3T3 Cells | Transcription, Genetic - drug effects | Cell Proliferation | Zinc Finger Protein GLI1 - metabolism | Humans | Gene Expression Regulation, Neoplastic | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | bcl-X Protein - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Molecular Mimicry | Transfection | Neoplasms - genetics | RNA Interference | Time Factors | Tumor Suppressor Proteins - genetics | HEK293 Cells | Female | Antineoplastic Agents - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - deficiency | Repressor Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Peptide Fragments - metabolism | Tumor Suppressor Proteins - metabolism | Signal Transduction | Cell Survival | Zinc Finger Protein GLI1 - genetics | Repressor Proteins - genetics | Genotype | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Mice, Knockout | Neoplasms - drug therapy | Phenotype | Animals | Mice, Nude | CRISPR-Cas Systems | Mice | Neoplasms - pathology | bcl-X Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Apoptosis | Regulators | Cell survival | Bcl-2 protein | Transcription | Decision making | Homology | Drug resistance | Gene expression | Mcl-1 protein | Proteins | Signaling | Mitochondria | DNA-binding protein | Bcl-x protein | Cell death | Feedforward | Deoxyribonucleic acid--DNA | Tumors | Cancer | Index Medicus
Journal Article
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 09/2008, Volume 28, Issue 17, pp. 5391 - 5402
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 7/2003, Volume 162, Issue 1, pp. 59 - 69
Journal Article
Journal Article