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index medicus (14) 14
pharmacology & pharmacy (14) 14
animals (13) 13
humans (12) 12
torsades-de-pointes (11) 11
female (10) 10
torsades de pointes (10) 10
cardiac & cardiovascular systems (9) 9
dogs (9) 9
electrocardiography (9) 9
torsades de pointes - chemically induced (9) 9
male (8) 8
torsades de pointes - physiopathology (8) 8
arrhythmia (7) 7
arrhythmias (7) 7
beat-to-beat variability of repolarization (7) 7
electrocardiogram (7) 7
time factors (7) 7
arrhythmias, cardiac - physiopathology (6) 6
repolarization (6) 6
short-term variability (6) 6
to-beat variability (6) 6
arrhythmias, cardiac - chemically induced (5) 5
beat-to-beat (5) 5
dofetilide (5) 5
heart (5) 5
long qt syndrome - chemically induced (5) 5
proarrhythmia (5) 5
prolongation (5) 5
qt prolongation (5) 5
action potential (4) 4
action potentials - drug effects (4) 4
analysis (4) 4
anti-arrhythmia agents - pharmacology (4) 4
beat‐to‐beat (4) 4
beat‐to‐beat variability of repolarization (4) 4
disease models, animal (4) 4
dose-response relationship, drug (4) 4
early afterdepolarizations (4) 4
heart rate - drug effects (4) 4
long-qt syndrome (4) 4
middle aged (4) 4
rabbits (4) 4
repolarization reserve (4) 4
restitution (4) 4
sudden cardiac death (4) 4
tachycardia (4) 4
action potential duration (3) 3
action-potential duration (3) 3
adult (3) 3
beat-to-beat variability (3) 3
biomarkers (3) 3
cardiac arrhythmia (3) 3
cardiovascular (3) 3
diagnosis (3) 3
drug-related side effects and adverse reactions (3) 3
electrophysiology (3) 3
heart - physiopathology (3) 3
heart conduction system - physiopathology (3) 3
heart rate - physiology (3) 3
heart-failure (3) 3
long qt syndrome - physiopathology (3) 3
myocytes, cardiac - drug effects (3) 3
phenethylamines - pharmacology (3) 3
physiology (3) 3
predictive value of tests (3) 3
research papers (3) 3
risk assessment - methods (3) 3
risk factors (3) 3
sulfonamides - pharmacology (3) 3
acquired long qt (2) 2
adolescent (2) 2
aged (2) 2
anesthesia (2) 2
anti-arrhythmia agents - therapeutic use (2) 2
anti-arrhythmia drugs (2) 2
arrhythmias, cardiac - etiology (2) 2
arrhythmias, cardiac - metabolism (2) 2
atrioventricular block - physiopathology (2) 2
atrioventricular-block (2) 2
canine model (2) 2
canine ventricular myocytes (2) 2
cardiac repolarization (2) 2
care and treatment (2) 2
case-control studies (2) 2
cellular basis (2) 2
chromans - administration & dosage (2) 2
chromans - toxicity (2) 2
complete av-block (2) 2
d-sotalol (2) 2
death (2) 2
disease susceptibility (2) 2
ekg (2) 2
electrical restitution (2) 2
electrocardiography - drug effects (2) 2
electrocardiography - methods (2) 2
fluoroquinolones (2) 2
healthy-subjects (2) 2
heart block - physiopathology (2) 2
heart conduction system - drug effects (2) 2
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1. Full Text Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study
by Hinterseer, Martin and Thomsen, Morten B and Beckmann, Britt-Maria and Pfeufer, Arne and Schimpf, Rainer and Wichmann, H.-Erich and Steinbeck, Gerhard and Vos, Marc A and Kaab, Stefan
European Heart Journal, ISSN 0195-668X, 1/2008, Volume 29, Issue 2, pp. 185 - 190
Aims Torsades de pointes arrhythmias (TdP) occur by definition in the setting of prolonged QT intervals. Animal models of drug induced Long-QT syndrome (dLQTS)... 
Beat-to-beat Variability of repolarization Proarrhythmia | Drug induced Long QT Syndrome | Torsades de Pointes | drug induced long QT syndrome | ARRHYTHMIAS | TORSADES-DE-POINTES | CARDIAC & CARDIOVASCULAR SYSTEMS | HEARTS | beat-to-beat variability of repolarization proarrhythmia | TACHYCARDIA | UNMASKS | PROLONGATION | REPOLARIZATION | SOTALOL | THERAPY | DOGS | Predictive Value of Tests | Disease Susceptibility | Humans | Middle Aged | Torsades de Pointes - chemically induced | Electrocardiography - drug effects | Long QT Syndrome - chemically induced | Male | Arrhythmias, Cardiac - etiology | Case-Control Studies | Heart Rate - drug effects | Pilot Projects | Heart Rate - physiology | Female | Aged | Torsades de Pointes - physiopathology
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2. Full Text Assessment of Efficacy of Proarrhythmia Biomarkers in Isolated Rabbit Hearts With Attenuated Repolarization Reserve
by Orosz, Szabolcs and Sarusi, Annamária and Csík, Norbert and Papp, Julius Gy and Varró, András and Farkas, Sándor and Forster, Tamás and Farkas, Attila S and Farkas, András
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 09/2014, Volume 64, Issue 3, pp. 266 - 276
Isolated hearts with reduced repolarization reserve would be suitable for assessing the proarrhythmic liability of drugs. However, it is not known which... 
Repolarization reserve | Langendorff perfused rabbit heart | Absolute beat-to-beat variability parameters | Biomarkers of proarrhythmia | Torsades de pointes | biomarkers of proarrhythmia | torsades de pointes | TORSADES-DE-POINTES | DOFETILIDE | CARDIAC & CARDIOVASCULAR SYSTEMS | CANINE MODEL | INSTABILITY | repolarization reserve | absolute beat-to-beat variability parameters | VENTRICULAR REPOLARIZATION | QT INTERVAL VARIABILITY | ACTION-POTENTIAL DURATION | IN-VIVO MODEL | PHARMACOLOGICAL BLOCK | PHARMACOLOGY & PHARMACY | CHANNEL BLOCKER | Biomarkers - metabolism | Rabbits | Phenethylamines - toxicity | Arrhythmias, Cardiac - chemically induced | Phenethylamines - pharmacology | Torsades de Pointes - chemically induced | Sulfonamides - pharmacology | Arrhythmias, Cardiac - physiopathology | Dose-Response Relationship, Drug | Phenethylamines - administration & dosage | Animals | Chromans - pharmacology | Electrocardiography | Female | Sulfonamides - toxicity | Chromans - toxicity | Torsades de Pointes - physiopathology | Chromans - administration & dosage | Sulfonamides - administration & dosage
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3. Full Text Progesterone pretreatment reduces the incidence of drug‐induced torsades de pointes in atrioventricular node‐ablated isolated perfused rabbit hearts
by Tisdale, James E and Jaynes, Heather A and Overholser, Brian R and Sowinski, Kevin M and Kovacs, Richard J
Journal of Cardiovascular Electrophysiology, ISSN 1045-3873, 06/2019, Volume 30, Issue 6, pp. 941 - 949
Introduction Higher progesterone concentrations are protective against drug‐induced prolongation of ventricular repolarization. We tested the hypothesis that... 
QT interval | beat‐to‐beat variability | torsades de pointes | isolated perfused heart | ventricular arrhythmias | progesterone | rabbit | dofetilide | beat-to-beat variability | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIAC REPOLARIZATION | SEX | RISK | QT INTERVAL PROLONGATION | HORMONE REPLACEMENT THERAPY | STEROID-HORMONES | TO-BEAT VARIABILITY | PROARRHYTHMIA | ESTRADIOL | Heart | Rabbits | Tachycardia | Electrocardiogram | Estrogen | Electrocardiography | Dofetilide | Progesterone | EKG | Ovariectomy | Implantation | Ablation | Estradiol | Nodes | Incidence | Sex hormones | Perfusion | Torsades de pointes | Sustained release | Ventricle | Pretreatment | Controlled release | Prolongation
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4. Full Text Microvolt T-wave alternans and beat-to-beat variability of repolarization during early postischemic remodeling in a pig heart
by Floré, Vincent, MD and Claus, Piet, PhD and Antoons, Gudrun, PhD and Oosterhoff, Peter, MSc and Holemans, Patricia, BSc and Vos, Marc A., PhD and Sipido, Karin R., MD, PhD and Willems, Rik, MD, PhD
Heart Rhythm, ISSN 1547-5271, 2011, Volume 8, Issue 7, pp. 1050 - 1057
Background Repolarization variability is considered to predict sudden cardiac death. T-wave alternans (TWA) has been the subject of exhaustive research,... 
Cardiovascular | Beat-to-beat variability of repolarization | Noninvasive risk stratification | T-wave alternans | Sudden cardiac death | Ischemic cardiomyopathy | ARRHYTHMIAS | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | SUDDEN | RISK STRATIFICATION | ISCHEMIA | DEATH | LEFT-VENTRICULAR DYSFUNCTION | CARDIAC ALTERNANS | DEFIBRILLATOR | CORONARY-ARTERY-DISEASE | Cardiac Resynchronization Therapy - methods | Tachycardia, Ventricular - complications | Follow-Up Studies | Death, Sudden, Cardiac - prevention & control | Death, Sudden, Cardiac - etiology | Magnetic Resonance Imaging, Cine | Tachycardia, Ventricular - physiopathology | Ventricular Remodeling | Animals | Heart Conduction System - physiopathology | Time Factors | Swine | Myocardial Ischemia - complications | Tachycardia, Ventricular - diagnosis | Death, Sudden, Cardiac - pathology | Electrocardiography | Heart Rate - physiology | Myocardial Ischemia - physiopathology | Disease Models, Animal | Implants, Artificial | Prosthesis | Electrocardiogram | Universities and colleges | Cardiology | Heart attack | Adenosine triphosphatase
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5. Full Text No proarrhythmic properties of the antibiotics Moxifloxacin or Azithromycin in anaesthetized dogs with chronic‐AV block
by Thomsen, M B and Beekman, J D M and Attevelt, N J M and Takahara, A and Sugiyama, A and Chiba, K and Vos, M A
British Journal of Pharmacology, ISSN 0007-1188, 12/2006, Volume 149, Issue 8, pp. 1039 - 1048
Background & purpose: The therapeutically available quinolone antibiotic moxifloxacin has been used as a positive control for prolonging the QT interval in... 
short‐term variability | torsades de pointes | electrophysiology | acquired long QT | proarrhythmia | action potential | beat‐to‐beat variability of repolarization | Beat-to-beat variability of repolarization | Short-term variability | Torsades de pointes | Acquired long QT | Electrophysiology | Action potential | Proarrhythmia | TORSADES-DE-POINTES | HEALTHY-SUBJECTS | RISK | beat-to-beat variability of repolarization | PROLONGATION | LONG-QT SYNDROME | short-term variability | REPOLARIZATION | CONSCIOUS DOGS | ACTION-POTENTIAL DURATION | EARLY AFTERDEPOLARIZATIONS | PHARMACOLOGY & PHARMACY | Fluoroquinolones | Arrhythmias, Cardiac - chemically induced | Electric Stimulation | Phenethylamines - pharmacology | Anti-Arrhythmia Agents - pharmacology | Heart Block - physiopathology | Torsades de Pointes - chemically induced | Azithromycin - toxicity | Long QT Syndrome - chemically induced | Aza Compounds - toxicity | Sulfonamides - pharmacology | Arrhythmias, Cardiac - physiopathology | Long QT Syndrome - physiopathology | Dose-Response Relationship, Drug | Heart Rate - drug effects | Animals | Electroencephalography - drug effects | Dogs | Anesthesia | Anti-Bacterial Agents - toxicity | Torsades de Pointes - physiopathology | Quinolines - toxicity | Research Papers
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6. Full Text Double pharmacological challenge on repolarization opens new avenues for drug safety research
by Thomsen, M B
British Journal of Pharmacology, ISSN 0007-1188, 08/2007, Volume 151, Issue 7, pp. 909 - 911
The pharmaceutical industry is testing new potential drugs for their propensity to prolong human cardiac repolarization, and regards this as a sign of... 
torsades de pointes | electrophysiology | repolarization reserve | drug research | action potential | proarrhythmia | beat‐to‐beat variability of repolarization | long QT | Beat-to-beat variability of repolarization | Repolarization reserve | Drug research | Torsades de pointes | Long QT | Electrophysiology | Action potential | Proarrhythmia | TORSADES-DE-POINTES | beat-to-beat variability of repolarization | I-KS | VENTRICULAR-MUSCLE | QT PROLONGATION | VARIABILITY | PHARMACOLOGY & PHARMACY | Phenethylamines - toxicity | Drug-Related Side Effects and Adverse Reactions - prevention & control | Potassium Channels, Voltage-Gated - physiology | Drug-Related Side Effects and Adverse Reactions - chemically induced | Humans | Long QT Syndrome - chemically induced | Long QT Syndrome - physiopathology | Phenethylamines - administration & dosage | Delayed Rectifier Potassium Channels - physiology | Potassium Channel Blockers - toxicity | Torsades de Pointes - physiopathology | Chromans - administration & dosage | Rabbits | Delayed Rectifier Potassium Channels - antagonists & inhibitors | Potassium Channel Blockers - administration & dosage | Risk Factors | Torsades de Pointes - chemically induced | Electrocardiography - drug effects | Potassium Channels, Voltage-Gated - antagonists & inhibitors | Drug Synergism | Animals | Dogs | Sulfonamides - toxicity | Chromans - toxicity | Sulfonamides - administration & dosage | Commentaries
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7. Full Text Biomarkers and endogenous determinants of dofetilide-induced torsades de pointes in α 1-adrenoceptor-stimulated, anaesthetized rabbits
by Farkas, Attila S and Rudas, László and Makra, Péter and Csík, Norbert and Leprán, István and Forster, Tamás and Csanády, Miklós and Papp, Julius Gy and Varró, András and Farkas, András
British Journal of Pharmacology, ISSN 0007-1188, 12/2010, Volume 161, Issue 7, pp. 1477 - 1495
BACKGROUND AND PURPOSE Torsades de pointes (TdP) liability is a stochastic event, which indicates that unidentified factors have an important role in... 
Absolute beat-to-beat variability and instability | Baroreflex | Torsades de pointes | Phenylephrine | Anaesthetized rabbit | Biomarkers | Dofetilide | adrenoceptor stimulation | Coupling interval | Preceding arrhythmias | preceding arrhythmias | ARRHYTHMIAS | torsades de pointes | D-SOTALOL | baroreflex | SHORT-TERM VARIABILITY | biomarkers | DELAYED REPOLARIZATION | coupling interval | PROLONGATION | dofetilide | ALPHA-ADRENOCEPTOR STIMULATION | alpha 1-adrenoceptor stimulation | anaesthetized rabbit | absolute beat-to-beat variability and instability | IN-VIVO MODEL | PROARRHYTHMIA | phenylephrine | SYMPATHETIC-NERVE ACTIVITY | PHARMACOLOGY & PHARMACY | LONG-QT-SYNDROME
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8. Full Text Dog left ventricular midmyocardial myocytes for assessment of drug‐induced delayed repolarization: short‐term variability and proarrhythmic potential
by Abi‐Gerges, Najah and Valentin, Jean‐Pierre and Pollard, Chris E
British Journal of Pharmacology, ISSN 0007-1188, 01/2010, Volume 159, Issue 1, pp. 77 - 92
Background and purpose:  Evaluation of the potential for delayed ventricular repolarization and proarrhythmia by new drugs is essential. We investigated if dog... 
Purkinje fibres | triangulation | left ventricular midmyocardial myocytes | action potential duration | beat‐to‐beat variability of repolarization | Beat-to-beat variability of repolarization | Triangulation | Action potential duration | Left ventricular midmyocardial myocytes | FEMALE RABBIT HEART | TORSADES-DE-POINTES | POTASSIUM CHANNELS | beat-to-beat variability of repolarization | QT INTERVAL PROLONGATION | CANINE PURKINJE-FIBERS | I-KS | ISOLATED CARDIAC-MUSCLE | DURATION PROLONGATION | PHARMACOLOGY & PHARMACY | ATRIOVENTRICULAR-BLOCK | OPTICAL ISOMERS | Drug Evaluation, Preclinical - methods | Risk Assessment - methods | Heart Ventricles - cytology | Purkinje Fibers - metabolism | Animals | Myocytes, Cardiac - drug effects | Purkinje Fibers - drug effects | Drug-Related Side Effects and Adverse Reactions | Dogs | Drug Design | Myocytes, Cardiac - metabolism | Female | Action Potentials - drug effects | Heart Ventricles - drug effects | Cardiac arrhythmia | Risk assessment | Themed Section
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9. Full Text Use of ECG Restitution (Beat‐to‐Beat QT‐TQ Interval Analysis) to Assess Arrhythmogenic Risk of QTc Prolongation with Guanfacine
by Fossa, Anthony A and Zhou, Meijian and Robinson, Antoine and Purkayastha, Jaideep and Martin, Patrick
Annals of Noninvasive Electrocardiology, ISSN 1082-720X, 11/2014, Volume 19, Issue 6, pp. 582 - 594
Background Guanfacine (Intuniv) is a centrally active alpha‐2A adrenergic agonist for the new indication of attention‐deficit/hyperactivity disorder. QTc (QTcF... 
QTc/QT prolongation | risk assessment | restitution | beat‐to‐beat | guanfacine | arrhythmia | beat-to-beat | VARIABILITY | DE-POINTES | CARDIAC & CARDIOVASCULAR SYSTEMS | REPOLARIZATION | Risk Assessment - methods | Arrhythmias, Cardiac - chemically induced | Double-Blind Method | Electrocardiography, Ambulatory - drug effects | Guanfacine - pharmacology | Humans | Electrocardiography, Ambulatory - methods | Long QT Syndrome - chemically induced | Male | Reference Values | Adrenergic alpha-2 Receptor Agonists - pharmacology | Cross-Over Studies | Dose-Response Relationship, Drug | Female | Retrospective Studies | Fluoroquinolones - administration & dosage | Hypertension | Usage | Arrhythmia | Electrocardiogram | Anti-arrhythmia drugs | Electrocardiography | Guanfacine | Attention deficit disorder | Drug therapy | Restitution
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10. Full Text DeltaT50—a new method to assess temporal ventricular repolarization variability
by Abrahamsson, Christina, PhD and Dota, Corina, MD and Skallefell, Bo, BSc and Carlsson, Leif, PhD and Halawani, Dunia, MSc and Frison, Lars, PhD and Berggren, Anders, MD, PhD and Edvardsson, Nils, MD, PhD and Duker, Göran, PhD and Sahlgrenska akademin and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
Journal of Electrocardiology, ISSN 0022-0736, 2011, Volume 44, Issue 4, pp. 477.e1 - 477.e9
Abstract Background Increased beat-to-beat variability in cardiac repolarization time is a tentative risk marker of drug-induced torsades de pointes. We... 
Cardiovascular | Repolarization instability | Automatic analysis | Beat-to-beat | QT variability | Humans | Middle Aged | Linear Models | Male | Reference Values | Arrhythmias, Cardiac - physiopathology | Analysis of Variance | Time Factors | Heart Conduction System - physiology | Adolescent | Aged, 80 and over | Electrocardiography | Adult | Female | Aged | Kardiologi | Cardiac and Cardiovascular Systems
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11. Full Text Decreasing the infusion rate reduces the proarrhythmic risk of NS‐7: confirming the relevance of short‐term variability of repolarisation in predicting drug‐induced torsades de pointes
by Detre, Elke and Thomsen, Morten B and Beekman, Jet D and Petersen, Karl‐Uwe and Vos, Marc A
British Journal of Pharmacology, ISSN 0007-1188, 06/2005, Volume 145, Issue 3, pp. 397 - 404
1 The rate of infusion has been suggested to be important for drug‐induced torsades de pointes (TdP) arrhythmias. We investigated the repolarisation‐prolonging... 
beat‐to‐beat variability of repolarisation | short‐term variability | torsades de pointes | Electrophysiology | acquired long QT | infusion rate | proarrhythmia | action potential | Short-term variability | Torsades de pointes | Acquired long QT | Action potential | Beat-to-beat variability of repolarisation | Infusion rate | Proarrhythmia | ARRHYTHMIAS | PROTEIN-KINASE | NA+/CA2+ CHANNEL | PROLONGATION | LONG-QT SYNDROME | short-term variability | NEUROPROTECTIVE AGENT | CA2+ CHANNEL BLOCKER | electrophysiology | EARLY AFTERDEPOLARIZATIONS | PHARMACOLOGY & PHARMACY | COMPLETE AV-BLOCK | beat-to-beat variability of repolarisation | CEREBRAL-ISCHEMIA | Predictive Value of Tests | Animals | Arrhythmias, Cardiac - chemically induced | Time Factors | Infusion Pumps | Pyrimidines - administration & dosage | Dogs | Torsades de Pointes - chemically induced | Infusions, Intravenous | Torsades de Pointes - physiopathology | Arrhythmias, Cardiac - physiopathology | Papers
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12. Full Text Effects of K201 on repolarization and arrhythmogenesis in anesthetized chronic atrioventricular block dogs susceptible to dofetilide-induced torsade de pointes
by Stams, Thom R.G and Oros, Avram and der Nagel, Roel van and Beekman, Jet D.M and Chamberlin, Paul and Dittrich, Howard C and Vos, Marc A
European Journal of Pharmacology, ISSN 0014-2999, 2011, Volume 672, Issue 1, pp. 126 - 134
The novel antiarrhythmic drug K201 (4‐[3-{1-(4‐benzyl)piperidinyl}propionyl]‐7‐methoxy‐2,3,4,5‐tetrahydro‐1,4‐benzothiazepine monohydrochloride) is currently... 
Ventricular arrhythmia | Beat-to-beat variability of repolarization duration | K201 | Safety pharmacology | Cardiac electrophysiology | JTV519 | D-SOTALOL | PIG VENTRICULAR MYOCYTES | HEART-FAILURE | SPONTANEOUS CA2+ RELEASE | NA/CA EXCHANGE | CELLULAR BASIS | TO-BEAT VARIABILITY | EARLY AFTERDEPOLARIZATIONS | RYANODINE RECEPTOR | PHARMACOLOGY & PHARMACY | CARDIOPROTECTIVE DRUG | Membrane Potentials - drug effects | Atrioventricular Block - physiopathology | Disease Susceptibility | Anti-Arrhythmia Agents - pharmacology | Torsades de Pointes - chemically induced | Male | Thiazepines - pharmacology | Atrioventricular Block - pathology | Dose-Response Relationship, Drug | Torsades de Pointes - pathology | Animals | Time Factors | Phenethylamines - adverse effects | Dogs | Sulfonamides - adverse effects | Anesthesia | Female | Torsades de Pointes - physiopathology | Chronic Disease | Torsades de Pointes - prevention & control | Animal experimentation | Analysis | Heart block | Atrial fibrillation | Anti-arrhythmia drugs
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13. Full Text Comparison of the IKr blockers moxifloxacin, dofetilide and E‐4031 in five screening models of pro‐arrhythmia reveals lack of specificity of isolated cardiomyocytes
by Nalos, L and Varkevisser, R and Jonsson, MKB and Houtman, MJC and Beekman, JD and van der Nagel, R and Thomsen, MB and Duker, G and Sartipy, P and de Boer, TP and Peschar, M and Rook, MB and van Veen, TAB and van der Heyden, MAG and Vos, MA
British Journal of Pharmacology, ISSN 0007-1188, 01/2012, Volume 165, Issue 2, pp. 467 - 478
BACKGROUND AND PURPOSE Drug development requires the testing of new chemical entities for adverse effects. For cardiac safety screening, improved assays are... 
human embryonic stem cell‐derived cardiomyocytes | methoxamine‐sensitized rabbit | chronic AV block dog | dofetilide | cardiac safety pharmacology | isolated cardiomyocytes | beat‐to‐beat variability of repolarization | moxifloxacin | TORSADES-DE-POINTES | CANINE MODEL | CARDIAC REPOLARIZATION | SHORT-TERM VARIABILITY | HEALTHY-SUBJECTS | POTASSIUM CHANNELS | human embryonic stem cell-derived cardiomyocytes | beat-to-beat variability of repolarization | LONG-QT SYNDROME | TO-BEAT VARIABILITY | EMBRYONIC STEM-CELLS | PHARMACOLOGY & PHARMACY | ATRIOVENTRICULAR-BLOCK | methoxamine-sensitized rabbit | Fluoroquinolones | Embryonic Stem Cells - cytology | Anti-Arrhythmia Agents - pharmacology | Humans | Heart Block - physiopathology | Aza Compounds - pharmacology | Quinolines - pharmacology | Piperidines - pharmacology | Female | Torsades de Pointes - physiopathology | Methoxamine | Action Potentials - drug effects | Potassium Channel Blockers - pharmacology | Disease Models, Animal | Heart - physiopathology | Cell Line | Rabbits | Phenethylamines - pharmacology | Torsades de Pointes - chemically induced | Sulfonamides - pharmacology | Animals | Myocytes, Cardiac - drug effects | Myocytes, Cardiac - physiology | Dogs | Heart - drug effects | Pyridines - pharmacology | Ventricular Remodeling - drug effects | Medical research | Cardiomyocytes | Stem cells | Index Medicus | Research Papers
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14. Full Text Utility of Short-Term Variability of Repolarization as a Marker for Monitoring a Safe Exercise Training Program in Patients With Cardiac Diseases
by Nishi, Isao and Sugiyama, Atsushi and Takahara, Akira and Kuroki, Kenji and Igawa, Masayuki and Enomoto, Tsuyoshi and Iida, Kaname and Koseki, Susumu and Aonuma, Kazutaka
International Heart Journal, ISSN 1349-2365, 2011, Volume 52, Issue 5, pp. 304 - 307
In order to begin searching for new markers for safe exercise training in patients with cardiac diseases, we tested the sensitivity and reliability of the... 
Repolarization reserve | Beat to beat variability of repolarization | Spatial dispersion | Temporal dispersion | Cardiac rehabilitation | ARRHYTHMIAS | CARDIAC & CARDIOVASCULAR SYSTEMS | PREVENTION | DEATH | SOCIETY | HEART | TO-BEAT VARIABILITY | QT INTERVALS
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15. Full Text Short-term beat-to-beat variability of the QT interval is increased and correlates with parameters of left ventricular hypertrophy in patients with hypertrophic cardiomyopathy
by Orosz, Andrea and Baczkó, István and Nagy, Viktória and Gavallér, Henriette and Csanády, Miklós and Forster, Tamás and Papp, Julius Gy and Varró, András and Lengyel, Csaba and Sepp, Róbert
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 04/2015, Volume 93, Issue 9, pp. 765 - 772
Stratification models for the prediction of sudden cardiac death (SCD) are inappropriate in patients with hypertrophic cardiomyopathy (HCM). We investigated... 
Repolarization | QT prolongation | Tpeak–Tend interval | Left ventricular hypertrophy | Hypertrophic cardiomyopathy | Sudden cardiac death | Short-term beat-to-beat variability of the QT interval | QT dispersion | LATE SODIUM CURRENT | TORSADES-DE-POINTES | PHYSIOLOGY | RISK-FACTORS | MYOCYTES | DISPERSION | HEART-FAILURE | repolarization | Tpeak-Tend interval | sudden cardiac death | END INTERVAL | left ventricular hypertrophy | PHARMACOLOGY & PHARMACY | hypertrophic cardiomyopathy | REPOLARIZATION LABILITY | short-term beat-to-beat variability of the QT interval | TEND INTERVAL | Echocardiography | Humans | Middle Aged | Male | Cardiomyopathy, Hypertrophic - complications | Arrhythmias, Cardiac - physiopathology | Case-Control Studies | Magnetic Resonance Imaging | Cardiomyopathy, Hypertrophic - physiopathology | Hypertrophy, Left Ventricular - pathology | Hypertrophy, Left Ventricular - complications | Electrocardiography | Adult | Female | Arrhythmias, Cardiac - complications | Hypertrophy, Left Ventricular - physiopathology | Cardiomyopathy, Hypertrophic | Diagnosis | Heart enlargement | Electrocardiogram | Methods | Heart | Care and treatment
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