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The New England Journal of Medicine, ISSN 0028-4793, 09/2018, Volume 379, Issue 11, pp. 1007 - 1016
Journal Article
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 06/2006, Volume 14, Issue 11, pp. 3758 - 3765
A series of N-(acridin-9-yl)-4-(benzo[d]imidazol/oxazol-2-yl) benzamides has been synthesized by the condensation of 9-aminoacridine derivatives with... 
Benzoxazole derivatives | Analgesic | Schiff's bases | Benzimidazole derivatives | Anti-inflammatory | CDK-5 and GSK-3 | CDK-1 | CHEMISTRY, MEDICINAL | analgesic | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | benzimidazole derivatives | GLYCOGEN-SYNTHASE KINASE-3-BETA | ANTICANCER | benzoxazole derivatives | anti-inflammatory | BIOLOGICAL EVALUATION | HETEROCYCLIC-COMPOUNDS | Analgesics - pharmacology | Benzoxazoles - pharmacology | Glycogen Synthase Kinase 3 - drug effects | Rats, Wistar | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Structure-Activity Relationship | Benzimidazoles - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Analgesics - chemical synthesis | CDC2 Protein Kinase - drug effects | Female | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Drug Evaluation, Preclinical - methods | Protein Kinases - drug effects | Cyclin-Dependent Kinase 5 - drug effects | Benzimidazoles - chemical synthesis | Rats | Enzyme Activation - drug effects | Benzoxazoles - chemical synthesis | Animals | Benzoxazoles - chemistry | Analgesics - chemistry | Schiff Bases - chemistry | Benzimidazoles - pharmacology | Mice | Analgesics | Anti-inflammatory drugs | Pharmaceutical industry | Condensation | Analysis | Anti-Inflammatory Agents, Non-Steroidal | CDC2 Protein Kinase | Benzimidazoles | Biochemistry, Molecular Biology | Glycogen Synthase Kinase 3 | Benzoxazoles | Cyclin-Dependent Kinase 5 | Life Sciences | Protein Kinases | Enzyme Activation | Schiff Bases | Drug Evaluation, Preclinical
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2005, Volume 40, Issue 9, pp. 949 - 959
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 06/2015, Volume 97, Issue 1, pp. 778 - 785
Journal Article
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 12/2018, Volume 81, pp. 191 - 202
[Display omitted] •Synthesis of new N-(2-(3,4,5-trimethoxybenzyl)benzoxazole-5-yl)benzamide derivatives.•In vitro biological evaluation of compounds by COX-2... 
Anti-inflammatory activity | Histopathology | COX-2 | COX-1 | N-(3,4,5-trimethoxybenzyl)benzoxazole | Ulcerogenic activity | DESIGN | CYCLOOXYGENASE-2 | ANALGESIC ACTIVITIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | ANTIMICROBIAL AGENTS | CHEMISTRY, ORGANIC | MOLECULAR DOCKING | PHARMACOPHORE | PHOSPHODIESTERASE 4B INHIBITORS | PHARMACOLOGICAL EVALUATION | BENZOXAZOLE DERIVATIVES | Inflammation - chemically induced | Rats, Wistar | Benzamides - pharmacokinetics | Humans | Structure-Activity Relationship | Benzoxazoles - toxicity | Anti-Ulcer Agents - pharmacokinetics | Benzamides - therapeutic use | Inflammation - drug therapy | Cyclooxygenase 2 Inhibitors - therapeutic use | Ibuprofen | Anti-Inflammatory Agents - therapeutic use | Anti-Inflammatory Agents - pharmacokinetics | Female | Molecular Structure | Anti-Ulcer Agents - toxicity | Cyclooxygenase 2 Inhibitors - toxicity | Cyclooxygenase 2 Inhibitors - chemical synthesis | Stomach Ulcer - chemically induced | Anti-Ulcer Agents - therapeutic use | Stomach - pathology | Benzamides - toxicity | Anti-Inflammatory Agents - toxicity | Benzoxazoles - therapeutic use | Stomach Ulcer - drug therapy | Enzyme Assays | Benzamides - chemical synthesis | Cyclooxygenase 2 Inhibitors - pharmacokinetics | Benzoxazoles - chemical synthesis | Animals | Anti-Ulcer Agents - chemical synthesis | Sheep | Anti-Inflammatory Agents - chemical synthesis | Molecular Docking Simulation | Carrageenan | Benzoxazoles - pharmacokinetics
Journal Article
Organic Letters, ISSN 1523-7060, 07/2012, Volume 14, Issue 13, pp. 3502 - 3505
Journal Article
Journal Article