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BLOOD, ISSN 0006-4971, 01/2012, Volume 119, Issue 3, pp. 884 - 893
Antiphospholipid Abs (APLAs) are associated with thrombosis and recurrent fetal loss. These Abs are primarily directed against phospholipid-binding proteins,... 
COMPLEX | DOMAIN | TOLL-LIKE RECEPTOR-4 | BETA-GLYCOPROTEIN I | LIPID RAFTS | NUCLEOLIN | SURFACE | KAPPA-B | HEMATOLOGY | TRANSCRIPTION FACTOR | BINDING
Journal Article
BLOOD, ISSN 0006-4971, 05/2014, Volume 123, Issue 22, pp. 3478 - 3487
A single-chain fragment variable(scFv) recognizing beta 2-glycoprotein 1 (beta 2GPI) from humans and other species was isolated from a human phage display... 
BETA-GLYCOPROTEIN I | PHAGE ANTIBODY | ANTICARDIOLIPIN ANTIBODIES | AUTOIMMUNE-DISEASES | IN-VIVO | DOMAIN-I | ENDOTHELIAL-CELLS | IGG ANTIBODIES | MONOCLONAL-ANTIBODIES | HEMATOLOGY | PEPTIDE
Journal Article
BLOOD, ISSN 0006-4971, 10/2011, Volume 118, Issue 15, pp. 4231 - 4238
In vitro studies have documented beta 2 glycoprotein I (beta 2GPI) binding to endothelial cells (ECs) and trophoblast using antiphospholipid antibodies. The in... 
INTERNATIONAL CONSENSUS STATEMENT | DEFINITE ANTIPHOSPHOLIPID SYNDROME | BETA-GLYCOPROTEIN I | COMPLEMENT ACTIVATION | MEDIATED THROMBOSIS | ENDOTHELIAL ACTIVATION | INDUCED FETAL LOSS | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | HEMATOLOGY | CLASSIFICATION CRITERIA | TISSUE FACTOR
Journal Article
CANCER SCIENCE, ISSN 1347-9032, 06/2019, Volume 110, Issue 6, pp. 1974 - 1986
We previously found that circulating beta(2)-glycoprotein I inhibits human endothelial cell migration, proliferation, and angiogenesis by diverse mechanisms.... 
site-directed mutagenesis | ANNEXIN A2 | BETA-2-GLYCOPROTEIN-I | PROLIFERATION | PHOSPHOLIPID-BINDING | ADHESION | protein structure analysis | INVASION | ONCOLOGY | anti-melanoma cell migration | GROWTH-FACTOR | recombinant beta-glycoprotein I polypeptide domain | melanoma growth
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 04/2017, Volume 198, Issue 7, pp. 2640 - 2648
Antiphospholipid syndrome (APS) is characterized by recurrent arterial/venous thrombosis and miscarriages in the persistent presence of autoantibodies against... 
RECEPTOR-DEFICIENT MICE | ANTIBODIES | MATRIX METALLOPROTEINASES | SYSTEMIC-LUPUS-ERYTHEMATOSUS | T-CELL CLONES | TARGET AUTOANTIGEN | HELPER | MYOCARDIAL-INFARCTION | BETA-GLYCOPROTEIN I | IMMUNOLOGY | HELICOBACTER-PYLORI
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, ISSN 1570-9639, 12/2018, Volume 1866, Issue 12, pp. 1232 - 1241
beta(2)-Glycoprotein I (beta(2)-GPI) is a plasma protein that binds to oxidized low-density lipoprotein (LDL) and negatively charged substances, and inhibits... 
Protein aggregation | LESION PROGRESSION | Interaction | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-2-GLYCOPROTEIN-I | LOW-DENSITY-LIPOPROTEIN | OXIDIZED LDL | Platelet aggregation | ANTIPHOSPHOLIPID SYNDROME | PHOSPHOLIPID-BINDING | DEPENDENT UPTAKE | 5TH DOMAIN | beta -Glycoprotein I | PLASMA | BIOPHYSICS | Lysophosphatidic acid | ENDOTHELIAL-CELLS | Blood clotting
Journal Article
JOURNAL OF HEART AND LUNG TRANSPLANTATION, ISSN 1053-2498, 11/2017, Volume 36, Issue 11, pp. 1258 - 1265
Journal Article
HAEMATOLOGICA, ISSN 0390-6078, 03/2019, Volume 104, Issue 4, pp. 819 - 826
Clinical studies have reported different diagnostic/predictive values of antibodies to domain 1 or 4/5 of beta(2)glycoproteinI in terms of risk of thrombosis... 
AUTOANTIBODIES | COMPLEMENT | INHIBITION | RECOGNIZE | BETA-GLYCOPROTEIN I | ENDOTHELIAL-CELLS | BETA-2-GLYCOPROTEIN-I | IGG ANTIBODIES | HEMATOLOGY | ASSOCIATION | BINDING
Journal Article
BLOOD, ISSN 0006-4971, 03/2005, Volume 105, Issue 5, pp. 1964 - 1969
Patients with antiphospholipid antibodies (APLAs) are at increased risk for arterial and venous thrombosis. Many APLAs associated with these events react with... 
TETRAMER | COMPLEX | TISSUE-PLASMINOGEN ACTIVATOR | SYSTEMIC LUPUS-ERYTHEMATOSUS | BETA-GLYCOPROTEIN I | THROMBOSIS | LOW-DENSITY-LIPOPROTEIN | RECEPTOR | T-PA | HEMATOLOGY | BINDING
Journal Article
THROMBOSIS RESEARCH, ISSN 0049-3848, 02/2018, Volume 162, pp. 38 - 43
Objective: IgG and IgM antibodies directed at beta 2-glycoprotein I are included in the classification criteria for the antiphospholipid syndrome (APS) while... 
Anti-RNP | MORTALITY | DIAGNOSIS | COMPLEMENT | ACTIVATION | IgA anti- beta 2GPI | APS | IgA anti-beta2 glycoprotein I | BETA-2-GLYCOPROTEIN-I | Thrombosis | Pregnancy morbidity | BETA-GLYCOPROTEIN I | PATHWAY | Anti-Sm | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | CLASSIFICATION CRITERIA | Antiphospholipid syndrome | Anti-SSA | CIRCULATING IMMUNE-COMPLEXES
Journal Article
ARTHRITIS & RHEUMATOLOGY, ISSN 2326-5191, 08/2015, Volume 67, Issue 8, pp. 2196 - 2204
Objective. It has been suggested that only antibodies against domain 1 (D1) of beta(2)-glycoprotein I (beta(2)GPI) are pathogenic and diagnostic. The role of... 
AUTOANTIBODIES | DIAGNOSIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | SYNDROME APS | RECOGNIZE | THROMBOSIS | BETA-2-GLYCOPROTEIN-I | ASSAYS | RHEUMATOLOGY | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | CLASSIFICATION CRITERIA
Journal Article
JOURNAL OF AUTOIMMUNITY, ISSN 0896-8411, 11/2014, Volume 54, pp. 72 - 80
Tolerogenic dendritic cells (tDCs) have the potential to control the outcome of autoimmunity by modulating the immune response. The aim of this study was to... 
Domain-V | ACTIVATION | ANTICARDIOLIPIN ANTIBODIES | BETA-2-GLYCOPROTEIN-I | TISSUE-FACTOR EXPRESSION | beta-glycoprotein-I | MICRORNAS | INDUCTION | IMMUNOLOGY | Domain-I | Tolerogenic dendritic cells | LUPUS | AUTOIMMUNE-DISEASES | ENDOTHELIAL-CELLS | T-CELLS | Antiphospholipid syndrome
Journal Article
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, ISSN 1538-7933, 08/2010, Volume 8, Issue 8, pp. 1754 - 1762
Background: beta(2)-Glycoprotein I (beta(2)GPI) is an abundant plasma protein that is closely linked to blood clotting, as it interacts with various protein... 
AUTOANTIBODIES | ACTIVATION | PROTEIN-DISULFIDE-ISOMERASE | thioredoxin | THROMBUS FORMATION | CRYSTAL-STRUCTURE | BETA-2-GLYCOPROTEIN-I | PLATELET-ADHESION | von Willebrand factor | PERIPHERAL VASCULAR DISEASE | GENERATION | oxidoreductase | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | HEMATOLOGY | beta-glycoprotein I | platelet adhesion | TISSUE FACTOR
Journal Article
BLOOD, ISSN 0006-4971, 01/2010, Volume 115, Issue 3, pp. 713 - 723
Antiphospholipid syndrome (APS) is an autoimmune thrombophilia characterized by arterial/venous thrombosis and/or pregnancy morbidity in the presence of... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATED PROTEIN-C | INTERNATIONAL CONSENSUS STATEMENT | BETA-GLYCOPROTEIN I | CRYSTAL-STRUCTURE | ENDOTHELIAL-CELLS | PLATELET ACTIVATION | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | HEMATOLOGY | CLASSIFICATION CRITERIA | HEPARIN-INDUCED THROMBOCYTOPENIA/THROMBOSIS
Journal Article
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