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Journal Article
Journal Article
Journal Article
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 07/2012, Volume 8, Issue 7, pp. 622 - 630
Functional selectivity of G protein-coupled receptor (GPCR) ligands toward different downstream signals has recently emerged as a general hallmark of this... 
PATHWAYS | ACTIVATION | CONFORMATIONAL-CHANGES | BETA-ARRESTIN-2 | ADENYLYL-CYCLASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INCREASES | PROTEIN-COUPLED RECEPTORS | FUNCTIONAL SELECTIVITY | BETA-ARRESTIN | SIGNALING COMPLEXES
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 09/2007, Volume 117, Issue 9, pp. 2445 - 2458
Deleterious effects on the heart from chronic stimulation of beta-adrenergic receptors (beta ARs), members of the 7 transmembrane receptor family, have... 
MEDICINE, RESEARCH & EXPERIMENTAL | GROWTH-FACTOR RECEPTOR | CARDIOMYOCYTE HYPERTROPHY | SIGNAL-REGULATED KINASES | PROTEIN-COUPLED RECEPTOR | HEART-FAILURE | CARDIAC DYSFUNCTION | BETA-ARRESTIN | ERK ACTIVATION | BETA-ADRENERGIC RECEPTOR | ANGIOTENSIN RECEPTOR
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2001, Volume 98, Issue 4, pp. 1601 - 1606
The two widely coexpressed isoforms of β-arrestin (termed β-arrestin 1 and 2) are highly similar in amino acid sequence. The β-arrestins bind phosphorylated... 
Hydrolysis | Biological Sciences | Receptors | 3T3 cells | HEK293 cells | Internalization | Cell lines | Antibodies | Inurement | Sensitization | Down regulation | CLATHRIN-MEDIATED ENDOCYTOSIS | INTERNALIZATION | STIMULATION | DESENSITIZATION | MULTIDISCIPLINARY SCIENCES | KINASE | ADAPTER | DOWN-REGULATION | PROTEIN-COUPLED RECEPTORS | ADRENERGIC-RECEPTOR | BETA-ADRENERGIC RECEPTOR
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 06/2015, Volume 131, Issue 24, pp. 2120 - 2130
Journal Article