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1. Full Text Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation
by Migliorini, Domenico and Biechele, Travis and Lyashenko, Natalia and Winter, Markus and Moon, Randall T and Hartmann, Christine
Nature cell biology, ISSN 1465-7392, 07/2011, Volume 13, Issue 7, pp. 753 - 761
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Embryonic Stem Cells - metabolism | Cell Proliferation | Cell Movement - genetics | Embryo, Mammalian - metabolism | Morphogenesis | TCF Transcription Factors - metabolism | Transfection | RNA Interference | Gene Expression Regulation, Developmental | Cell Differentiation | Neurons - metabolism | Binding Sites | Biomarkers - metabolism | Cell Line | Promoter Regions, Genetic | beta Catenin - deficiency | gamma Catenin - metabolism | Signal Transduction - genetics | Cell Adhesion | Gestational Age | beta Catenin - metabolism | beta Catenin - genetics | Mice, Knockout | Animals | Embryo, Mammalian - cytology | Mice | Index Medicus
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2. Full Text Reactivating head regrowth in a regeneration-deficient planarian species
by Liu, S.-Y and Selck, C and Friedrich, B and Lutz, R and Vila-Farré, M and Dahl, A and Brandl, H and Lakshmanaperumal, N and Henry, I and Rink, J.C
Nature (London), ISSN 0028-0836, 2013, Volume 500, Issue 7460, pp. 81 - 84
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | beta Catenin - deficiency | Molecular Sequence Data | Planarians - anatomy & histology | Planarians - physiology | Head - growth & development | Tail - growth & development | Wnt Proteins - metabolism | beta Catenin - metabolism | beta Catenin - genetics | Head - physiology | beta Catenin - biosynthesis | Regeneration | Animals | Body Patterning | Models, Animal | Wnt Signaling Pathway | Physiological aspects | Platyhelminthes | Regeneration (Biology) | Research | Genes | Cloning | Amputation | Ligands | Genetic engineering | Histology | Hybridization | Experiments | Defects | Index Medicus
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3. Full Text Wnt/β‐catenin signalling induces MLL to create epigenetic changes in salivary gland tumours
by Wend, Peter and Fang, Liang and Zhu, Qionghua and Schipper, Jörg H and Loddenkemper, Christoph and Kosel, Frauke and Brinkmann, Volker and Eckert, Klaus and Hindersin, Simone and Holland, Jane D and Lehr, Stephan and Kahn, Michael and Ziebold, Ulrike and Birchmeier, Walter
The EMBO journal, ISSN 0261-4189, 07/2013, Volume 32, Issue 14, pp. 1977 - 1989
cancer | tumour propagating cells/cancer stem cells | therapy | epigenetics | Wnt/beta‐catenin | Epigenetics | Therapy | Tumour propagating cells/cancer stem cells | Wnt/beta-catenin | Cancer | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Myeloid-Lymphoid Leukemia Protein - metabolism | Salivary Gland Neoplasms - genetics | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Epigenesis, Genetic | Humans | Transplantation, Heterologous | CREB-Binding Protein - antagonists & inhibitors | Head and Neck Neoplasms - metabolism | CREB-Binding Protein - metabolism | Bone Morphogenetic Proteins - metabolism | Neoplastic Stem Cells - metabolism | Mice, Mutant Strains | Salivary Gland Neoplasms - metabolism | Neoplastic Stem Cells - pathology | Pyrimidinones - pharmacology | Mice, Transgenic | Mice, SCID | beta Catenin - metabolism | Head and Neck Neoplasms - pathology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Histone Methyltransferases | Wnt Signaling Pathway - drug effects | Histone-Lysine N-Methyltransferase - metabolism | beta Catenin - antagonists & inhibitors | Head and Neck Neoplasms - genetics | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | Mutation | Salivary Gland Neoplasms - pathology | Index Medicus | tumour propagating cells | beta-catenin | cancer stem cells | Wnt
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4. Full Text The regulation of β-catenin activity and function in cancer: Therapeutic opportunities
by Shang, Shuang and Hua, Fang and Hu, Zhuo-Wei
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 20, pp. 33972 - 33989
Protein stability | Wnt signaling | Transcriptional regulation | Cancer therapy | Subcellular localization | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Humans | Gene Expression Regulation, Neoplastic | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | beta Catenin - metabolism | beta Catenin - genetics | Neoplasms - drug therapy | Protein Transport | Ubiquitination | Wnt Signaling Pathway - drug effects | Neoplasms - genetics | Proteolysis | beta Catenin - antagonists & inhibitors | Protein Binding | Antineoplastic Agents - pharmacology | Protein Stability | Index Medicus
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5. Full Text Notch post-translationally regulates β-catenin protein in stem and progenitor cells
by Kwon, Chulan and Cheng, Paul and King, Isabelle N and Andersen, Peter and Shenje, Lincoln and Nigam, Vishal and Srivastava, Deepak
Nature cell biology, ISSN 1465-7392, 10/2011, Volume 13, Issue 10, pp. 1244 - 1251
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Embryonic Stem Cells - metabolism | Colonic Neoplasms - genetics | Cell Proliferation | Humans | Glycogen Synthase Kinase 3 beta | Colonic Neoplasms - metabolism | Transfection | RNA Interference | Cell Differentiation | Membrane Proteins - metabolism | Immunoglobulin J Recombination Signal Sequence-Binding Protein - genetics | Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism | Signal Transduction | beta Catenin - deficiency | Receptor, Notch1 - metabolism | Glycogen Synthase Kinase 3 - metabolism | beta Catenin - metabolism | beta Catenin - genetics | Mice, Knockout | HT29 Cells | Nerve Tissue Proteins - metabolism | Animals | Mice | Protein Processing, Post-Translational | Receptor, Notch1 - genetics | Index Medicus
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6. Full Text Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival
by Kato, Hideki and Gruenwald, Antje and Suh, Jung Hee and Miner, Jeffrey H and Barisoni-Thomas, Laura and Taketo, Makoto M and Faul, Christian and Millar, Sarah E and Holzman, Lawrence B and Susztak, Katalin
The Journal of biological chemistry, ISSN 0021-9258, 07/2011, Volume 286, Issue 29, pp. 26003 - 26015
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Albuminuria - complications | Humans | Cell Survival - genetics | Apoptosis - genetics | Male | Wnt Proteins - metabolism | Cell Differentiation - genetics | Wnt Proteins - genetics | Glomerular Basement Membrane - pathology | Albuminuria - metabolism | Protein Stability | Cell Adhesion - genetics | Diabetic Nephropathies - pathology | Genetic Predisposition to Disease | Glomerular Basement Membrane - metabolism | Podocytes - metabolism | Diabetic Nephropathies - metabolism | beta Catenin - deficiency | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Diabetic Nephropathies - genetics | Signal Transduction - genetics | Podocytes - pathology | Gene Knockout Techniques | beta Catenin - metabolism | beta Catenin - genetics | Diabetic Nephropathies - complications | Podocytes - cytology | Animals | Mice | Index Medicus | Molecular Bases of Disease | beta-Catenin | Epithelial Cell | Diabetes | Wnt Pathway | Kidney | Apoptosis
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7. Full Text Genotype‐phenotype correlation of CTNNB1 mutations reveals different ß‐catenin activity associated with liver tumor progression
by Rebouissou, Sandra and Franconi, Andrea and Calderaro, Julien and Letouzé, Eric and Imbeaud, Sandrine and Pilati, Camilla and Nault, Jean‐Charles and Couchy, Gabrielle and Laurent, Alexis and Balabaud, Charles and Bioulac‐Sage, Paulette and Zucman‐Rossi, Jessica
Hepatology (Baltimore, Md.), ISSN 0270-9139, 12/2016, Volume 64, Issue 6, pp. 2047 - 2061
Genetic Association Studies | Liver Neoplasms - genetics | Carcinoma, Hepatocellular - genetics | Humans | beta Catenin - physiology | Mutation | Tumor Cells, Cultured | Adenoma, Liver Cell - genetics | Disease Progression | beta Catenin - genetics | Index Medicus
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8. Full Text Targeting Wnt/β-catenin pathway in hepatocellular carcinoma treatment
by Vilchez, Valery and Turcios, Lilia and Marti, Francesc and Gedaly, Roberto
World journal of gastroenterology : WJG, ISSN 1007-9327, 01/2016, Volume 22, Issue 2, pp. 823 - 832
Hepatocellular carcinoma | Liver cancer stem cells | Molecular therapy | Wnt/β-catenin pathway | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Liver Neoplasms - genetics | Humans | Liver Neoplasms - drug therapy | Treatment Outcome | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Cell Transformation, Neoplastic - metabolism | beta Catenin - metabolism | beta Catenin - genetics | Animals | Carcinoma, Hepatocellular - drug therapy | Wnt Signaling Pathway - drug effects | Cell Transformation, Neoplastic - genetics | beta Catenin - antagonists & inhibitors | Carcinoma, Hepatocellular - genetics | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Liver Neoplasms - pathology | Cell Transformation, Neoplastic - pathology | Carcinoma, Hepatocellular - metabolism | Index Medicus | Review | β-catenin pathway | Wnt
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