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Journal of Biological Chemistry, ISSN 0021-9258, 06/2017, Volume 292, Issue 24, pp. 9865 - 9881
The glucagon receptor (GCGR) belongs to the secretin-like (class B) family of G protein-coupled receptors (GPCRs) and is activated by the peptide hormone... 
BETA ADRENERGIC-RECEPTOR | LIGAND-BINDING | GLUCAGON RECEPTOR | IONIC LOCK | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CROSS-LINKING STRATEGY | METAPHYSEAL CHONDRODYSPLASIA | BETA-ADRENERGIC RECEPTOR | PEPTIDE | MUSCARINIC ACETYLCHOLINE-RECEPTOR | Receptor, Parathyroid Hormone, Type 1 - chemistry | Receptors, Corticotropin-Releasing Hormone - metabolism | Receptor, Parathyroid Hormone, Type 1 - metabolism | Humans | Receptors, Corticotropin-Releasing Hormone - agonists | Receptors, Corticotropin-Releasing Hormone - genetics | Receptor, Parathyroid Hormone, Type 1 - agonists | Recombinant Fusion Proteins - metabolism | Receptors, Vasoactive Intestinal Polypeptide, Type I - agonists | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - chemistry | Conserved Sequence | Protein Interaction Domains and Motifs | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - agonists | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Receptors, Vasoactive Intestinal Polypeptide, Type I - metabolism | Protein Stability | Binding Sites | Peptide Fragments - genetics | Second Messenger Systems | Receptors, Glucagon - agonists | Receptors, Glucagon - genetics | Receptors, Vasoactive Intestinal Polypeptide, Type I - chemistry | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Peptide Fragments - metabolism | Mutagenesis, Site-Directed | Models, Molecular | Receptors, Glucagon - metabolism | Recombinant Proteins - chemistry | Recombinant Fusion Proteins - chemistry | Receptors, Vasoactive Intestinal Polypeptide, Type I - genetics | Peptide Fragments - chemistry | Peptide Fragments - agonists | Receptors, Glucagon - chemistry | Hydrophobic and Hydrophilic Interactions | Receptor, Parathyroid Hormone, Type 1 - genetics | Ligands | Protein Conformation | Structural Homology, Protein | Mutation | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | Receptors, Corticotropin-Releasing Hormone - chemistry | Amino Acid Substitution | Index Medicus | Editors' Picks | 7-helix receptor | G protein-coupled receptor (GPCR) | parathyroid hormone | glucagon | arrestin
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 01/2003, Volume 50, Issue 1, pp. 5 - 25
The aim of the current study is to investigate whether homology models of G‐Protein‐Coupled Receptors (GPCRs) that are based on bovine rhodopsin are reliable... 
docking | scoring | homology modeling | GPCRs | structure‐based ligand design | Docking | Scoring | Structure-based ligand design | Homology modeling | BETA ADRENERGIC-RECEPTOR | AGONIST ACTIVATION | LIGAND-BINDING | BIOCHEMISTRY & MOLECULAR BIOLOGY | structure-based ligand design | MUSCARINIC RECEPTOR | DELTA-OPIOID RECEPTOR | INDUCED CONFORMATIONAL-CHANGES | TRANSMEMBRANE REGIONS | BIOPHYSICS | SCORING FUNCTIONS | 3-DIMENSIONAL MODELS | BETA-ADRENERGIC RECEPTOR | Humans | Molecular Sequence Data | Heterotrimeric GTP-Binding Proteins - metabolism | Adrenergic beta-2 Receptor Agonists | Receptors, Cell Surface - antagonists & inhibitors | Drug Delivery Systems | Receptors, Adrenergic, beta-2 - chemistry | Receptors, Vasopressin - chemistry | Cattle | Computer Simulation | Receptors, Dopamine D2 - chemistry | Receptors, Cell Surface - chemistry | Databases, Factual | Rhodopsin - chemistry | Amino Acid Sequence | Computational Biology - methods | Receptors, Opioid, delta - chemistry | Receptors, Dopamine D2 - agonists | Receptors, Cell Surface - agonists | Models, Molecular | Receptor, Muscarinic M1 | Receptors, Muscarinic - chemistry | Sequence Homology, Amino Acid | Sequence Alignment | Algorithms | Animals | Receptors, Dopamine D3 | Ligands | Antidiuretic Hormone Receptor Antagonists | Dopamine D2 Receptor Antagonists | Receptors, Opioid, delta - agonists | Index Medicus
Journal Article
Journal Article
Journal Article
Psychopharmacology, ISSN 0033-3158, 2/2012, Volume 219, Issue 3, pp. 751 - 761
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2004, Volume 279, Issue 52, pp. 54291 - 54303
Adaptor and scaffolding proteins determine the cellular targeting, the spatial, and thereby the functional association of G protein-coupled seven-transmembrane... 
3RD INTRACELLULAR LOOP | GROWTH-FACTOR RECEPTOR | BETA-2-ADRENERGIC RECEPTOR | EXCHANGER REGULATORY FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | SYNAPTIC-TRANSMISSION | METABOTROPIC GLUTAMATE RECEPTORS | BETA-ARRESTIN | OPIOID RECEPTORS | BETA-ADRENERGIC RECEPTOR | Receptors, Opioid, delta - metabolism | Receptors, Tachykinin - genetics | Surface Plasmon Resonance | Receptors, Tachykinin - metabolism | Vesicular Transport Proteins - metabolism | Humans | Molecular Sequence Data | Peptide Library | Recombinant Fusion Proteins - metabolism | Receptors, Adrenergic, beta-2 - chemistry | Sodium-Hydrogen Exchangers - metabolism | Cell Membrane - chemistry | Endocytosis | Glutathione Transferase - genetics | Lysosomes - metabolism | Phosphoproteins | Receptors, Opioid, delta - genetics | Gene Deletion | Receptors, Cell Surface - chemistry | Cell Membrane - metabolism | Peptide Fragments - genetics | Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins | Amino Acid Sequence | Peptide Fragments - metabolism | Receptors, Adrenergic, beta-2 - genetics | Receptors, Opioid, delta - chemistry | Receptors, Cell Surface - metabolism | Receptors, Adrenergic, beta-2 - metabolism | Peptide Fragments - chemistry | Carrier Proteins - metabolism | Mutagenesis | Receptors, Tachykinin - chemistry | Receptors, Cell Surface - genetics | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, pp. e46039 - e46039
A highly crystallizable T4 lysozyme (T4L) was fused to the N-terminus of the beta(2) adrenergic receptor (beta(2)AR), a G-protein coupled receptor (GPCR) for... 
COMPLEX | ANTAGONIST | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | GPCR | BETA-ADRENERGIC RECEPTOR | MUSCARINIC ACETYLCHOLINE-RECEPTOR | Protein Engineering - methods | Receptors, G-Protein-Coupled - metabolism | Humans | Molecular Sequence Data | Crystallography, X-Ray | Tritium | Recombinant Fusion Proteins - metabolism | Viral Proteins - metabolism | Receptors, Adrenergic, beta-2 - chemistry | Sf9 Cells | Bacteriophage T4 - enzymology | Binding Sites | Binding, Competitive | Protein Structure, Tertiary | Amino Acid Sequence | Protein Structure, Secondary | Muramidase - chemistry | Receptors, Adrenergic, beta-2 - genetics | Viral Proteins - chemistry | Muramidase - genetics | Crystallization | Models, Molecular | Viral Proteins - genetics | Muramidase - metabolism | Recombinant Fusion Proteins - chemistry | Receptors, Adrenergic, beta-2 - metabolism | Animals | Dihydroalprenolol - metabolism | Protein Binding | Recombinant Fusion Proteins - genetics | Dihydroalprenolol - chemistry | Protein Conformation | Receptors, G-Protein-Coupled - genetics | Mutation | Receptors, G-Protein-Coupled - chemistry | Proteins | Lysozyme | G proteins | Protein engineering | G protein-coupled receptors | Crystal lattices | Science | Catecholamines | Crystallography | Medicine | Signaling | N-Terminus | Chemical bonds | Adrenergic receptors | Physiology | Crystal structure | Index Medicus
Journal Article
Journal Article
Neuropsychobiology, ISSN 0302-282X, 12/2011, Volume 65, Issue 1, pp. 12 - 19
Aims: There is evidence that psychological stress can modulate immune functions. It has been hypothesized that acute stressors can affect both immune balance... 
Original Paper | β | Acute stress | IFN-γ | IFN-γ receptor | Immunomodulation | Glucocorticoid receptor | Adrenergic receptor | beta-Adrenergic receptor | SOCIAL STRESS | PSYCHIATRY | INDUCED ANXIETY | NEUROSCIENCES | INFLAMMATORY CYTOKINE | PSYCHOLOGY | LEUKOCYTE DISTRIBUTION | MENTAL STRESS | RESPONSES | IN-VITRO | IFN-gamma | IFN-gamma receptor | MESSENGER-RNA | PSYCHOSOCIAL STRESS | ACUTE PSYCHOLOGICAL STRESS | T-Lymphocytes, Regulatory - metabolism | Catecholamines - metabolism | Humans | Middle Aged | Male | Receptors, Adrenergic, beta-2 - immunology | Receptors, Glucocorticoid - metabolism | Th2 Cells - immunology | Receptors, Catecholamine - immunology | Th1 Cells - immunology | Receptors, Catecholamine - metabolism | Stress, Psychological - immunology | T-Lymphocytes, Regulatory - immunology | Th1 Cells - metabolism | Interleukin-10 - metabolism | Adult | Female | Receptors, Cytokine - metabolism | Receptors, Catecholamine - genetics | Cytokines - genetics | Real-Time Polymerase Chain Reaction | Receptors, Cytokine - genetics | Receptors, Interferon - genetics | Transforming Growth Factor beta - immunology | Interferon-gamma | Gene Expression | Cytokines - metabolism | Receptors, Adrenergic, beta-2 - genetics | Receptors, Interleukin-4 - metabolism | Receptors, Glucocorticoid - immunology | Receptors, Interleukin-4 - immunology | Th2 Cells - metabolism | Receptors, Adrenergic, beta-2 - metabolism | Transforming Growth Factor beta - genetics | Receptors, Interferon - immunology | Interleukin-10 - genetics | Receptors, Interleukin-4 - genetics | Receptors, Glucocorticoid - genetics | Receptors, Cytokine - immunology | Interleukin-10 - immunology | Transforming Growth Factor beta - metabolism | Index Medicus
Journal Article
Journal of Chemical Information and Modeling, ISSN 1549-9596, 05/2015, Volume 55, Issue 5, pp. 1045 - 61
Journal Article