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1. Rspondin-1 Deficiency Enhances Beta Cell Neogenesis in a Murine Model of Diabetes
by Chahal, Jasleen
06/2013
The cWnt activator, Rspondin-1 (Rspo1), has been identified as a regulator of β-cell growth and function, although its role in pathophysiological conditions... 
beta-cell | neogenesis | apoptosis | 0719 | Rspondin-1 | diabetes
Dissertation
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2. Characterization of an Iducible Beta-cell Specific UCP2 Deletion Mouse Model
by Guo, Qian-yu
11/2012
In order to elucidate how uncoupling protein 2 (UCP2) influences pancreatic β cells and glucose homeostasis, I have generated and characterized an inducible β... 
beta-cell function | 0719 | Physiology | Diabetes | Endocrinology
Dissertation
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3. Full Text Glikokortykosteroidy a czynność komórek beta
by Fichna, Marta and Fichna, Piotr
Endokrynologia Polska, ISSN 0423-104X, 11/2017, Volume 68, Issue 5, pp. 568 - 578
Glucocorticoids | Beta cell | Insulin
Journal Article
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4. Full Text Proinsulin is sensitive to reflect glucose intolerance
by Nakamura, Akinobu and Miyoshi, Hideaki and Ukawa, Shigekazu and Nakamura, Koshi and Nakagawa, Takafumi and Terauchi, Yasuo and Tamakoshi, Akiko and Atsumi, Tatsuya
Journal of diabetes investigation, ISSN 2040-1116, 06/2019
We investigated associations between glucose tolerance and β-cell function using a series of estimation methods in a population-based study. Data from the... 
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5. Full Text Ameliorative effect of borneol, a natural bycyclic monoterpene against hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic Wistar rats
by Kodikonda, Madhuri and Naik, Prakash Ramachandra
Biomedicine and Pharmacotherapy, ISSN 0753-3322, 12/2017, Volume 96, pp. 336 - 347
Diabetes mellitus is a major public health problem worldwide. Oxidative stress plays a pivotal role in the pathogenesis of diabetes as it is one of the... 
Hypoglycemic | Beta cell | Hypolipidemic | Antioxidant | Insulin | Streptozotocin
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6. Full Text Thematic review series: High density lipoprotein structure, function, and metabolism cardioprotective functions of HDLs 1
by Rye, Kerry-Anne and Barter, Philip J
Journal of Lipid Research, ISSN 0022-2275, 02/2014, Volume 55, Issue 2, pp. 168 - 179
Cholesterol effl ux | Endothelial repair | Angiogenesis | Pancreatic beta cell function | Vascular infl ammation | Oxidation | Endothelial function | Thrombosis | Apoptosis
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7. Full Text Protective effects of Clec11a in islets against lipotoxicity via modulation of proliferation and lipid metabolism in mice
by Shi, Ruifeng and Hu, Juan and Li, Wei and Wang, Xiaohang and Wang, Zhirong and Pan, Ye and Bai, Mei and Mao, Wantong and Zhong, Ming and Yuan, Yang and Lau, Joey and Sun, Zilin and Zhao, Sheng
Experimental Cell Research, ISSN 0014-4827, 11/2019, Volume 384, Issue 1, p. 111613
The lipotoxicity is considered as one of the risk for diabetes. Here we report C-type lectin domain family 11, member A (Clec11a) as a new regulator in islet... 
Clec11a | Islet | Proliferation | Lipotoxicity | Beta cell
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8. Full Text Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach
by Inzucchi, S.E and Bergenstal, R.M and Buse, J.B and Diamant, M and Ferrannini, E and Nauck, M and Peters, A.L and Tsapas, A and Wender, R and Matthews, D.R
Diabetes Care, ISSN 0149-5992, 2012, Volume 35, Issue 6, pp. 1364 - 1379
LIFE-STYLE MODIFICATION | DIPEPTIDYL PEPTIDASE-4 INHIBITORS | GLYCEMIC CONTROL | CLINICAL-TRIAL | COMBINATION THERAPY | HEART-FAILURE | ENDOCRINOLOGY & METABOLISM | INCRETIN-BASED THERAPIES | COMPARING INSULIN DETEMIR | BETA-CELL | BLOOD-GLUCOSE CONTROL
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9. Effects of Enteroendocrine Hormones on Beta-cell Function and Glucose Homeostasis
by Maida, Adriano
06/2011
Mechanisms to augment the cellular function and mass of beta-cells may be effective means of treating type 2 diabetes. Important in the physiological control... 
GLP-1 | beta-cell | 0564 | incretin | 0719 | diabetes | GIP
Dissertation
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10. Full Text IPP-1 controls Akt/CREB phosphorylation extension in A 2a adenosine receptor signaling cascade in MIN6 pancreatic β-cell line
by Shahrestanaki, Mohammad Keyvanloo and Arasi, Fatemeh Panahi and Aghaei, Mahmoud
European Journal of Pharmacology, ISSN 0014-2999, 05/2019, Volume 850, pp. 88 - 96
Signaling through A adenosine receptor specifically prevent pancreatic β-cells (PBCs) loses under diabetogenic conditions. However, signaling mediators of this... 
adenosine receptor | Pancreatic beta Cell | CGS 21680 | Diabetes | IPP-1
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11. Full Text Effects of an enzymatically stable C-terminal hexapseudopeptide fragment peptide of xenin-25, ψ-xenin-6, on pancreatic islet function and metabolism
by Craig, S.L and Gault, V.A and McClean, S and Hamscher, G and Irwin, N
Molecular and Cellular Endocrinology, ISSN 0303-7207, 10/2019, Volume 496, p. 110523
Xenin-25 undergoes rapid enzyme metabolism following secretion. Early studies demonstrated bioactivity of a C-terminal hexapeptide fragment of xenin-25, namely... 
Xenin-6 | Beta-cell | Diabetes | Glucagon | Insulin | Xenin-25
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12. Full Text IPP-1 controls Akt/CREB phosphorylation extension in A2a adenosine receptor signaling cascade in MIN6 pancreatic β-cell line
by Shahrestanaki, Mohammad Keyvanloo and Arasi, Fatemeh Panahi and Aghaei, Mahmoud
European Journal of Pharmacology, ISSN 0014-2999, 05/2019, Volume 850, pp. 88 - 96
Signaling through A adenosine receptor specifically prevent pancreatic β-cells (PBCs) loses under diabetogenic conditions. However, signaling mediators of this... 
Pancreatic beta Cell | A2a adenosine receptor | CGS 21680 | Diabetes | IPP-1
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13. ZnT8 Zinc Transporter in the Regulation of Pancreatic Beta Cell Function and Glucose Homeostasis
by Wijesekara, Nadeeja
11/2010
Zinc levels in pancreatic islets are amongst the highest in the body and reduction in its levels in the pancreas has been associated with diabetes. The link... 
beta cell | pancreatic islet | insulin | 0719 | diabetes | zinc
Dissertation
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14. Insulin-induced Suppression of A-type GABA Receptor Signaling in the INS-1 Pancreatic β-cell Line
by Bansal, Pritpal
11/2010
GABA and GABA type A receptor (GABAAR) are expressed in pancreatic β-cells and comprise an autocrine signaling system. How the GABA-GABAAR system is regulated... 
Beta-cell | GABA | Electrophysiology | GABA receptor | 0719 | Islet | Autocrine | Insulin
Dissertation
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15. Investigating the Role of ATF6Beta in the ER Stress Response of Pancreatic Beta-cells
by Odisho, Tanya
11/2013
Endoplasmic reticulum (ER) stress has been implicated as a causative factor in the development of pancreatic beta-cell dysfunction and death resulting in type... 
ATF6beta | unfolded protein response | pancreatic beta-cell | ER stress | ATF6 signaling pathway | 0719 | Diabetes | Apoptosis
Dissertation
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16. Full Text Synthesis and Characterization of Urofuranoic Acids: In Vivo Metabolism of 2-(2-Carboxyethyl)-4-methyl-5-propylfuran-3carboxylic Acid (CMPF) and Effects on in Vitro Insulin Secretion
by Nagy, E and Liu, Y and Prentice, KJ and Sloop, KW and Sanders, PE and Batchuluun, B and Hammond, CD and Wheeler, MB and Durham, TB
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 03/2017, Volume 60, Issue 5, pp. 1860 - 1875
CMPF (2-(2-carboxyethyl)-4-methyl-5-propyl- furan-3-carboxylic acid) is a metabolite that circulates at high concentrations in type 2 and gestational diabetes... 
CHEMISTRY, MEDICINAL | BETA-CELL DYSFUNCTION | 3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPANOIC ACID | FURAN FATTY-ACIDS
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17. Full Text Autophagy and Aging
by Rubinsztein, David C and Mariño, Guillermo and Kroemer, Guido
Cell, ISSN 0092-8674, 2011, Volume 146, Issue 5, pp. 682 - 695
Genetic inhibition of autophagy induces degenerative changes in mammalian tissues that resemble those associated with aging, and normal and pathological aging... 
LIFE-SPAN EXTENSION | NEURODEGENERATIVE DISEASE | CAENORHABDITIS-ELEGANS | MEDIATED AUTOPHAGY | PROMOTE LONGEVITY | INSULIN-RESISTANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CALORIC RESTRICTION | MAMMALIAN AUTOPHAGY | BETA-CELL MASS | DIETARY RESTRICTION | CELL BIOLOGY | Aging | Animals | Signal Transduction | Autophagy | Humans | Analysis | Medical genetics | Resveratrol
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18. Full Text A unique allosteric insulin receptor monoclonal antibody that prevents hypoglycemia in the SUR-1
by Patel, Puja and Charles, Lawrenshey and Corbin, John and Goldfine, Ira D and Johnson, Kirk and Rubin, Paul and De León, Diva D
mAbs, ISSN 1942-0862, 07/2018, Volume 10, Issue 5, pp. 796 - 802
Loss-of-function mutations of the ß-cell ATP-sensitive potassium channels (K ATP ) cause the most common and severe form of congenital hyperinsulinism (K ATP... 
beta cell | hyperinsulinism | insulin | pancreas | hypoglycemia
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19. Full Text Effect of Vitamin D-3 Supplementation on Improving Glucose Homeostasis and Preventing Diabetes: A Systematic Review and Meta-Analysis
by Seida, JC and Mitri, J and Colmers, IN and Majumdar, SR and Davidson, MB and Edwards, AL and Hanley, DA and Pittas, AG and Tjosvold, L and Johnson, JA
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, ISSN 0021-972X, 10/2014, Volume 99, Issue 10, pp. 3551 - 3560
Context: Observational studies report consistent associations between low vitamin D concentration and increased glycemia and risk of type 2 diabetes, but... 
INSULIN-RESISTANCE | BLOOD-GLUCOSE | D-DEFICIENT | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | WEIGHT-LOSS | RANDOMIZED CONTROLLED-TRIAL | PLACEBO-CONTROLLED TRIAL | ENDOTHELIAL FUNCTION | CARDIOVASCULAR RISK-FACTORS | BETA-CELL FUNCTION
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20. Full Text Decreased beta-cell function in breastfeeding obese and non-obese women: A prospective observational study
by Harreiter, Jürgen and Vila, Greisa and Leitner, Karoline and Wattar, Luna and Leutner, Michael and Worda, Christof and Bancher-Todesca, Dagmar and Kautzky-Willer, Alexandra
Clinical Nutrition, ISSN 0261-5614, 2018
Background & aims: Obesity is associated with lower breastfeeding rates. The underlying pathophysiological mechanisms are not well-understood, but there is... 
Obesity | Breastfeeding | Prolactin | Beta-cell function | Insulin secretion | Postpartum
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