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1. Full Text Identification of a LIF-Responsive, Replication-Competent Subpopulation of Human β Cells
by Rosado-Olivieri, Edwin A and Aigha, Idil I and Kenty, Jennifer H and Melton, Douglas A
Cell metabolism, ISSN 1550-4131, 02/2020, Volume 31, Issue 2, pp. 327 - 338.e6
single cell | CEBPD | STAT3 | LIF | beta-cell replication | diabetes | beta cells | beta-cell regeneration | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
Journal Article
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2. Full Text Pancreatic Pericytes in Glucose Homeostasis and Diabetes
by Landsman, Limor
04/2019, Advances in Experimental Medicine and Biology, ISBN 3030110923, Volume 1122
Type 2 diabetes | Pancreatic pericytes | Islet pericytes | Beta-cells | Islet capillaries | Glucose homeostasis | Beta-cell function | Islet vasculature | Beta-cell dysfunction | Beta-cell mass | Glucose-stimulated insulin secretion | Islets of Langerhans | Humans | Pericytes - cytology | Glucose - metabolism | Homeostasis | Diabetes Mellitus, Type 2 | Insulin-Secreting Cells - cytology | Insulin
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3. Full Text Beta cell dysfunction and insulin resistance
by Cerf, Marlon E
Frontiers in endocrinology (Lausanne), ISSN 1664-2392, 2013, Volume 4, pp. 37 - 37
Obesity | Oxidative stress | Diabetes | Proliferation | Beta cell compensation | beta cell compensation | Oxidative Stress | proliferation | diabetes
Journal Article
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4. Full Text A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice
by Demine, Stephane and Garcia Ribeiro, Rita and Thevenet, Julien and Marselli, Lorella and Marchetti, Piero and Pattou, Francois and Kerr-Conte, Julie and Devoogdt, Nick and Eizirik, Decio L
Diabetologia, ISSN 0012-186X, 04/2020, Volume 63, Issue 4, pp. 825 - 836
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Bone grafts | Immunohistochemistry | Peptidase | Syngeneic grafts | Immunodeficiency | Pancreatic islet transplantation | Propidium iodide | Cell viability | Diabetes mellitus (insulin dependent) | Glucose | Neuroblastoma | Insulin | Single photon emission computed tomography | Beta cells | Allografts | Computed tomography | Cell death | Pancreas transplantation | Islet cells | Diabetes | Positron emission tomography | Enzyme-linked immunosorbent assay | Index Medicus
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5. Full Text Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity
by Oshima, Masaya and Pechberty, Severine and Bellini, Lara and Gopel, Sven O and Campana, Melanie and Rouch, Claude and Dairou, Julien and Cosentino, Cristina and Fantuzzi, Federica and Toivonen, Sanna and Marchetti, Piero and Magnan, Christophe and Cnop, Miriam and Le Stunff, Herve and Scharfmann, Raphael
Diabetologia, ISSN 0012-186X, 02/2020, Volume 63, Issue 2, pp. 395 - 409
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Animal models | Secretion | Sox9 protein | Lipids | mRNA | Inflammation | Stearoyl-CoA desaturase | Dietary intake | Glucose | Myc protein | Desaturase | Palmitic acid | Insulin | Fructose | Beta cells | Cell lines | Stem cells | Diabetes | Pancreas | Diabetes mellitus (non-insulin dependent) | Endoplasmic reticulum | Pluripotency | Apoptosis | Index Medicus | Life Sciences | Human health and pathology | Endocrinology and metabolism | Human | Type 2 diabetes | Lipotoxicity | Dedifferentiation | Pancreatic beta cell
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6. Full Text Islet cells are the source of Wnts that can induce beta‐cell proliferation in vitro
by Maschio, Daniela A and Matheus, Valquíria A and Collares‐Buzato, Carla B
Journal of cellular physiology, ISSN 0021-9541, 11/2019, Volume 234, Issue 11, pp. 19852 - 19865
MIN6 cells | pancreatic beta‐cell | endocrine pancreas | Wnt signaling pathway | cell proliferation | prediabetes | high‐fat diet | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Type 2 diabetes | Pancreatic beta cells | Gene expression | Prediabetic state | Cell proliferation | Wnt protein | Secretion | Diabetes mellitus | Insulinoma | Paracrine signalling | Cell differentiation | Insulin | High fat diet | Beta cells | Cell growth | Islet cells | Mice | Pancreas | Diabetes mellitus (non-insulin dependent) | Index Medicus
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7. Full Text Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival
by Hu, Ruiying and Walker, Emily and Huang, Chen and Xu, Yanwen and Weng, Chen and Erickson, Gillian E and Coldren, Anastasia and Yang, Xiaodun and Brissova, Marcela and Kaverina, Irina and Balamurugan, Appakalai N and Wright, Christopher V.E and Li, Yan and Stein, Roland and Gu, Guoqiang
Developmental cell, ISSN 1534-5807, 05/2020, Volume 53, Issue 4, pp. 390 - 405.e10
beta cell death | post-transcriptional control | Myelin transcription factors | stress response | beta cell compensation | proliferation | heat-shock proteins | diabetes | ATF4 | beta cell failure | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Diabetes Mellitus - pathology | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Cell Proliferation | Heat-Shock Proteins - metabolism | Humans | Stress, Physiological | Activating Transcription Factor 4 - genetics | Diabetes Mellitus - metabolism | Male | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mice, Knockout | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Heat-Shock Proteins - genetics | Insulin-Secreting Cells - metabolism | Animals | Activating Transcription Factor 4 - metabolism | Female | Insulin-Secreting Cells - cytology | Mice | Insulin Secretion | Index Medicus
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8. Full Text Biphasic voltage‐dependent inactivation of human NaV1.3, 1.6 and 1.7 Na+ channels expressed in rodent insulin‐secreting cells
by Godazgar, Mahdieh and Zhang, Quan and Chibalina, Margarita V and Rorsman, Patrik
The Journal of physiology, ISSN 0022-3751, 05/2018, Volume 596, Issue 9, pp. 1601 - 1626
electrical activity | pancreatic beta‐cell | insulin secretion | voltage‐gated sodium channels | voltage‐dependent inactivation | voltage-dependent inactivation | pancreatic beta-cell | voltage-gated sodium channels | Insulin | Pancreatic beta cells | Tetrodotoxin | Sodium channels | Protein composition | Sodium channels (voltage-gated) | Action potential | Pancreas | Membrane proteins | Research Paper | Molecular and cellular
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9. Full Text Loss of cyclin-dependent kinase 2 in the pancreas links primary β-cell dysfunction to progressive depletion of β-cell mass and diabetes
by Kim, So Yoon and Lee, Ji-Hyeon and Merrins, Matthew J and Gavrilova, Oksana and Bisteau, Xavier and Kaldis, Philipp and Satin, Leslie S and Rane, Sushil G
The Journal of biological chemistry, ISSN 0021-9258, 03/2017, Volume 292, Issue 9, pp. 3841 - 3853
Cyclin-Dependent Kinase 2 - metabolism | Glucose Tolerance Test | Phosphorylation | Body Weight | Cell Proliferation | Humans | Cyclin-Dependent Kinase 2 - genetics | Pancreas - pathology | Genotype | Male | Disease Progression | Mice, Knockout | Insulin - metabolism | Phenotype | Animals | Diet, High-Fat | Glucose - chemistry | Diabetes Mellitus, Experimental - pathology | Female | Insulin-Secreting Cells - cytology | Mice | Insulin-Secreting Cells - pathology | Insulin Secretion | Microscopy, Fluorescence | Index Medicus | foxo1 | FOXO | cell cycle | CDK2 | cyclin-dependent kinase (CDK) | Metabolism | beta cell (B-cell) | diabetes | beta cell function | beta cell mass | Cell and Molecular Biology | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cell- och molekylärbiologi | Medicinska och farmaceutiska grundvetenskaper
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10. Full Text The blockade of cytoplasmic HMGB1 modulates the autophagy/apoptosis checkpoint in stressed islet beta cells
by Chung, Hyunwoo and Nam, Hyunsung and Nguyen-Phuong, Thuy and Jang, Jiyun and Hong, Sung Ji and Choi, So Won and Park, Seung Bum and Park, Chung-Gyu
Biochemical and biophysical research communications, ISSN 0006-291X, 01/2021, Volume 534, pp. 1053 - 1058
HMGB1 | Lipotoxicity | Autophagy | Beta cell | Apoptosis | Index Medicus
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11. Full Text Functional loss of pancreatic islets in type 2 diabetes: How can we halt it?
by Marrano, Nicola and Biondi, Giuseppina and Cignarelli, Angelo and Perrini, Sebastio and Laviola, Luigi and Giorgino, Francesco and Natalicchio, Annalisa
Metabolism, clinical and experimental, ISSN 0026-0495, 09/2020, Volume 110, pp. 154304 - 154304
Human pancreatic islets | Beta-cell mass | Diabetes | Anti-diabetes drugs | Beta-cell function | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Index Medicus
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