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The EMBO Journal, ISSN 0261-4189, 07/2015, Volume 34, Issue 13, pp. 1759 - 1772
Journal Article
Diabetologia, ISSN 0012-186X, 8/2017, Volume 60, Issue 8, pp. 1454 - 1466
Pancreatic beta-like cells generated from human induced pluripotent stem cells (hiPSCs) or human embryonic stem cells (hESCs) offer an appealing donor tissue... 
BMP4 | Medicine & Public Health | Human Physiology | Metabolic Diseases | Beta-like cells | Sodium cromoglicate | Internal Medicine | Insulin–neurogenin 3 | Small molecule | Human iPSC | PROGENITOR CELLS | ANTIALLERGIC DRUGS | HUMAN IPS CELLS | BETA-CELLS | MAST-CELLS | Insulin-neurogenin 3 | PLURIPOTENT STEM-CELLS | ISLET TRANSPLANTATION | IN-VITRO | DISODIUM-CROMOGLYCATE | ENDOCRINOLOGY & METABOLISM | INSULIN-PRODUCING CELLS | Embryonic Stem Cells - metabolism | Induced Pluripotent Stem Cells - drug effects | Homeodomain Proteins - metabolism | Humans | Pancreas - cytology | Male | Pancreas - metabolism | Bone Morphogenetic Protein 4 - metabolism | Insulin-Secreting Cells - metabolism | Animals | Cromolyn Sodium - pharmacology | Embryonic Stem Cells - drug effects | Insulin-Secreting Cells - drug effects | Cell Differentiation - drug effects | Trans-Activators - metabolism | Insulin-Secreting Cells - cytology | Mice | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - metabolism | Embryonic stem cells | Bone morphogenetic proteins | Analysis | Explants | Cell culture | Bone morphogenetic protein 4 | Embryo cells | Stem cell transplantation | Gene expression | Ribonucleic acid--RNA | Insulin | Neurogenin 3 | Neurogenin | Homeobox | Sodium | Rodents | Stem cells | Pancreas | Growth factors | Pluripotency | Inhibitory postsynaptic potentials | Index Medicus
Journal Article
STEM CELL RESEARCH & THERAPY, ISSN 1757-6512, 10/2018, Volume 9, Issue 1, pp. 277 - 277
BackgroundTransplantation of pancreatic cells generated in vitro from pluripotent stem cells (hPSCs) such as embryonic stem cells (ESCs) or induced pluripotent... 
MEDICINE, RESEARCH & EXPERIMENTAL | PROGENITORS | Transcription factors | Pancreatic cells | PDX1 | Embryonic stem cells | Synthetic mRNAs | BETA-LIKE CELLS | CELL BIOLOGY | IN-VITRO | IPSCS | INSULIN-PRODUCING CELLS | siPOU5F1 | GENERATION | Endocrine differentiation | NKX6 | Glucagon - biosynthesis | RNA, Small Interfering - genetics | RNA, Messenger - chemical synthesis | Homeodomain Proteins - metabolism | Human Embryonic Stem Cells - cytology | Humans | Insulin - biosynthesis | Octamer Transcription Factor-3 - genetics | Insulin-Secreting Cells - metabolism | Lipids - chemistry | Cell Engineering - methods | Transfection | Trans-Activators - genetics | Cell Differentiation | Insulin-Secreting Cells - cytology | Human Embryonic Stem Cells - metabolism | RNA, Messenger - genetics | Cells, Cultured | Gene Expression Regulation | Octamer Transcription Factor-3 - antagonists & inhibitors | Homeodomain Proteins - genetics | Somatostatin - biosynthesis | Octamer Transcription Factor-3 - metabolism | Trans-Activators - metabolism | RNA, Small Interfering - metabolism | Messenger RNA | Research | Cell differentiation | Pancreas | Health aspects | Immunohistochemistry | Glucagon | Genomics | Stem cells | Transplantation | DNA binding proteins | Diabetes therapy | Cell culture | Syngeneic grafts | Oct-4 protein | Embryo cells | Mesoderm | Genomes | Experiments | Somatostatin | Endoderm | Nkx6.1 protein | Therapeutic applications | Diabetes mellitus | Pancreatic islet transplantation | Tumorigenicity | Insulin | Embryos | Polymerase chain reaction | Musculoskeletal system | Pancreas transplantation | Diabetes | Pluripotency | Inhibitory postsynaptic potentials | Index Medicus | Pancreatic β cells
Journal Article
Cell Reports, ISSN 2211-1247, 04/2017, Volume 19, Issue 2, pp. 281 - 294
Journal Article
Diabetes, ISSN 0012-1797, 12/2015, Volume 64, Issue 12, pp. 4123 - 4134
The exocrine pancreas can give rise to endocrine insulin-producing cells upon ectopic expression of key transcription factors. However, the need for genetic... 
PROGENITOR CELLS | INSULIN | IN-VITRO | EMBRYONIC STEM-CELLS | MOUSE | ENDOCRINOLOGY & METABOLISM | OSTEOGENIC PROTEIN-1 | MESENCHYMAL TRANSITION | IDENTIFICATION | BETA-LIKE CELLS | EXPRESSION | C-Peptide - blood | Bone Morphogenetic Protein 7 - genetics | Homeodomain Proteins - metabolism | Humans | Pancreas, Exocrine - pathology | Male | Transplantation, Heterologous | Pancreas, Exocrine - drug effects | Diabetes Mellitus, Experimental - therapy | Kidney | Diabetes Mellitus, Experimental - blood | Insulin-Secreting Cells - metabolism | Cell Transdifferentiation - drug effects | Diabetes Mellitus, Experimental - metabolism | C-Peptide - metabolism | Insulin Secretion | Biomarkers - metabolism | Recombinant Proteins - metabolism | Cells, Cultured | Transplantation, Heterotopic | Recombinant Proteins - pharmacology | Cell Lineage | Insulin - metabolism | Animals | Insulin-Secreting Cells - drug effects | Mice, Nude | Bone Morphogenetic Protein 7 - metabolism | Fluorescent Antibody Technique | Diabetes Mellitus, Experimental - pathology | Trans-Activators - metabolism | Pancreas, Exocrine - metabolism | Insulin-Secreting Cells - pathology | Bone Morphogenetic Protein 7 - pharmacology | Insulin-Secreting Cells - transplantation | Care and treatment | Analysis | Aging | Insulin resistance | Cystic fibrosis | Influence | Diabetes | Research | Proteins | Tissue | Transcription factors | Adults | Pancreas | Insulin | Index Medicus | Abridged Index Medicus | Islet Studies
Journal Article
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 06/2009, Volume 296, Issue 6, pp. 1258 - 1270
Myostatin is a negative regulator of skeletal muscle size, previously shown to inhibit muscle cell differentiation. Myostatin requires both Smad2 and Smad3... 
MAFbx | Mammalian target of rapamycin complex signaling | MuRF1 | S6 kinase | Smad signaling | Human skeletal muscle cells | Transducer of regulated Ca | responsive element-binding protein activity | MuRF-1 | Atrogin | Transforming growth factor-β-like molecules | IGF-I | PHYSIOLOGY | ATROPHY | RAPID DISUSE | human skeletal muscle cells | transforming growth factor-beta-like molecules | SKELETAL-MUSCLE HYPERTROPHY | FOXO TRANSCRIPTION FACTORS | UBIQUITIN LIGASES | transducer of regulated Ca2+-responsive element-binding protein activity | CELL BIOLOGY | atrogin | PATHWAY | GROWTH | GENE-EXPRESSION | mammalian target of rapamycin complex signaling | CONDITIONAL ACTIVATION | Activin Receptors, Type I - antagonists & inhibitors | Protein Kinases - metabolism | Phosphorylation | Protein Kinases - genetics | Humans | Smad3 Protein - metabolism | Muscle Fibers, Skeletal - drug effects | Tripartite Motif Proteins | Smad3 Protein - genetics | Transfection | RNA Interference | Myoblasts, Skeletal - pathology | Smad2 Protein - genetics | Muscle Proteins - metabolism | Dioxoles - pharmacology | Regulatory-Associated Protein of mTOR | Benzamides - pharmacology | Myostatin - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Rapamycin-Insensitive Companion of mTOR Protein | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Signal Transduction | Cell Size - drug effects | Cells, Cultured | Smad2 Protein - metabolism | Ubiquitin-Protein Ligases - metabolism | Organ Size | Activin Receptors, Type I - metabolism | Myoblasts, Skeletal - enzymology | SKP Cullin F-Box Protein Ligases - metabolism | Mice, SCID | Myostatin - antagonists & inhibitors | Adaptor Proteins, Signal Transducing | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Cell Differentiation - drug effects | Follistatin - pharmacology | Muscle Fibers, Skeletal - pathology | Creatine Kinase - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | TOR Serine-Threonine Kinases | Myoblasts, Skeletal - drug effects | Insulin-Like Growth Factor I - metabolism | Muscle Fibers, Skeletal - enzymology | RNA, Small Interfering - metabolism | Abdominal surgery | Musculoskeletal system | Signal transduction | Cell growth | Kinases | Gene expression | Cells | Index Medicus
Journal Article
Biomaterials, ISSN 0142-9612, 09/2019, Volume 216, pp. 119266 - 119266
iPSCs-derived insulin-producing cell transplantation is a promising strategy for diabetes therapy. Although there have been many protocols of mature,... 
iPSCs | Differentiation | β-like cells | Competing endogenous RNA | Long noncoding RNAs | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | TRANSCRIPTION | GENE-EXPRESSION | beta-like cells | REVERSAL
Journal Article
International Journal of Molecular Medicine, ISSN 1107-3756, 12/2011, Volume 28, Issue 6, pp. 1019 - 1024
Journal Article
Virology, ISSN 0042-6822, 02/2019, Volume 528, pp. 37 - 47
In vertebrates, pyroptosis is an intense inflammatory form of programmed cell death. This death pathway is critical for controlling pathogenic infection. In... 
Caspase 1 | Cell death | IL-1β-like protein | Shrimp | WSSV | PATHWAYS | APOPTOSIS | DEFENSE | RECOGNITION | IL-1 beta-like protein | ASC | VIROLOGY | ROLES | INFLAMMASOME | NLRP3 | REQUIREMENT | Virus diseases | Enzymes | Marine biology | Biochemistry | Health aspects | Index Medicus
Journal Article
Apoptosis, ISSN 1360-8185, 6/2015, Volume 20, Issue 6, pp. 778 - 786
The amyloid precursor like protein-1 (APLP1) belongs to the amyloid precursor protein family that also includes the amyloid precursor protein (APP) and the... 
Biochemistry, general | Biomedicine | Cell death | dFoxO | Drosophila | APLP1 | Cancer Research | Oncology | Cell Biology | Virology | HUMAN NEUROBLASTOMA-CELLS | NERVOUS-SYSTEM | ALZHEIMERS-DISEASE | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SECRETASE CLEAVAGE | AXONAL-TRANSPORT | AMYLOID PRECURSOR PROTEIN