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by Wu, JP and Yan, Z and Li, ZQ and Qian, XY and Lu, S and Dong, MQ and Zhou, Q and Yan, NE
NATURE, ISSN 0028-0836, 09/2016, Volume 537, Issue 7619, pp. 191 - 191
The voltage-gated calcium (Ca-v) channels convert membrane electrical signals to intracellular Ca2+-mediated events. Among the ten subtypes of Ca-v channel in... 
ACCURATE DETERMINATION | INACTIVATION | SKELETAL-MUSCLE | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | CA2+ CHANNEL | RECEPTOR | RESTORATION | ALPHADELTA SUBUNITS | SODIUM-CHANNEL | BETA-SUBUNIT
Journal Article
Journal Article
NATURE, ISSN 0028-0836, 01/2019, Volume 565, Issue 7740, pp. 516 - 516
Type A gamma-aminobutyric acid (GABA(A)) receptors are pentameric ligand-gated ion channels and the main drivers of fast inhibitory neurotransmission in the... 
ACTIVATION | DESENSITIZATION | MULTIDISCIPLINARY SCIENCES | PURIFICATION | NICOTINIC ACETYLCHOLINE-RECEPTOR | BINDING-SITE | CHANNELS | MUTATIONS | PROTEINS | BETA-SUBUNIT | MODULATION
Journal Article
2017, Advances in experimental medicine and biology, ISBN 9811032335, Volume 962, xx, 515 pages
This volume provides the reader with an overview of the diverse functions of the RUNX family of genes. As highlighted in the introduction and several of the 29... 
physiology | Core Binding Factor Alpha 1 Subunit | Life sciences | Research | DNA-binding proteins | Neoplasms | Cell Growth Processes | Cancer | etiology | Biochemistry | Gene Function | Protein Science | Oncology | Biomedicine | Proteins
Book
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 06/2014, Volume 111, Issue 24, pp. 8979 - 8984
Ca(V)1 and Ca(V)2 voltage-gated calcium channels are associated with beta and alpha(2)delta accessory subunits. However, examination of cell surface-associated... 
PREGABALIN | PROTEIN | ALPHA-2-SUBUNIT | MULTIDISCIPLINARY SCIENCES | TRAFFICKING | CA2+ CHANNEL | IDENTIFICATION | GABAPENTIN | BETA-SUBUNIT | EXPRESSION | MODULATION
Journal Article
NATURE, ISSN 0028-0836, 05/2009, Volume 459, Issue 7245, pp. 446 - U167
Sodium-potassium ATPase is an ATP-powered ion pump that establishes concentration gradients for Na+ and K+ ions across the plasma membrane in all animal cells... 
DOMAIN | NA,K-ATPASE BETA-SUBUNIT | PROTEIN | CHOLESTEROL | RECTAL GLANDS | MULTIDISCIPLINARY SCIENCES | CATION-BINDING | NA+,K+-ATPASE | CALCIUM-PUMP | IDENTIFICATION | ATP
Journal Article
Channels, ISSN 1933-6950, 01/2019, Volume 13, Issue 1, pp. 440 - 454
Pentameric GABA A receptors are composed from 19 possible subunits. The GABA A β subunit is unique because the β 1 and β 3 subunits can assemble and traffic to... 
chimera | beta subunit | trafficking | theta subunit | GABAA
Journal Article
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, ISSN 1943-0264, 03/2010, Volume 2, Issue 3, pp. 51 - 64
The IKK kinase complex is the core element of the NF-kappa B cascade. It is essentially made of two kinases (IKK alpha and IKK beta) and a regulatory subunit,... 
KINASE-ALPHA | UBIQUITIN-CONJUGATING ENZYME | PHOSPHORYLATION | SEVERE LIVER DEGENERATION | TRANSCRIPTION | RECEPTOR | REQUIRES | MICE LACKING | BETA SUBUNIT | NEMO/IKK-GAMMA | CELL BIOLOGY | 040
Journal Article
AMERICAN JOURNAL OF HUMAN GENETICS, ISSN 0002-9297, 09/2016, Volume 99, Issue 3, pp. 704 - 710
GNB5 encodes the G protein beta subunit 5 and is involved in inhibitory G protein signaling. Here, we report mutations in GNB5 that are associated with... 
G-BETA-5 | COMPLEX | ACTIVATION | GENE | LIGHT | GENETICS & HEREDITY | MICE | HEART-RATE | POLYMORPHISM | BETA-SUBUNIT | BRAIN
Journal Article
The Journal of Clinical Investigation, ISSN 0021-9738, 06/2008, Volume 118, Issue 6, pp. 2260 - 2268
Brugada syndrome is a genetic disease associated with sudden cardiac death that is characterized by ventricular fibrillation and right precordial ST segment... 
SKELETAL-MUSCLE | SCN5A MUTATION | BETA-1 SUBUNIT | FUNCTIONAL EXPRESSION | EXTRACELLULAR DOMAIN | XENOPUS OOCYTES | LONG-QT SYNDROME | FEBRILE SEIZURES | ST-SEGMENT ELEVATION | UMCG Approved | BETA SUBUNIT | MEDICINE, RESEARCH & EXPERIMENTAL
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 03/2016, Volume 113, Issue 11, pp. 2940 - 2945
High-resolution crystal structures of the headpiece of lymphocyte function-associated antigen-1 (integrin alpha(L)beta(2)) reveal how the alpha I domain... 
COMPLEX | ACTIVATION | RECOGNITION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ECTODOMAIN | RECEPTOR | MODEL | PROTEINS | BETA-SUBUNIT | BINDING
Journal Article
CELL, ISSN 0092-8674, 04/2019, Volume 177, Issue 3, pp. 499 - 501
One of the 2019 Canada Gairdner International Awards recognizes Timothy Springer's discovery of the first immune system adhesion molecules involved in... 
LFA-1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISTINCT | FIBRONECTIN | BETA-SUBUNIT | DOMAINS | CELL BIOLOGY | Integrins
Journal Article
JAMA OPHTHALMOLOGY, ISSN 2168-6165, 06/2019, Volume 137, Issue 6, pp. 679 - 680
In this issue of JAMA Ophthalmology, Khateb et al1 fill a key knowledge gap by providing a comprehensive retrospective analysis of retinitis pigmentosa (RP)... 
CGMP | OPHTHALMOLOGY | BETA-SUBUNIT | Retinitis pigmentosa | Retina | Retinitis | Ophthalmology | Nyctalopia | Acuity | Phosphodiesterase
Journal Article
NATURE, ISSN 0028-0836, 02/2008, Volume 451, Issue 7180, pp. 830 - U9
Ca2+/ calmodulin- dependent regulation of voltage- gated Ca(V)1 - 2 Ca2+ channels shows extraordinary modes of spatial Ca2+ decoding and channel... 
GAMMA | MULTIDISCIPLINARY SCIENCES | MECHANISMS | FRET | FACILITATION | BETA-SUBUNIT | EXPRESSION | GATED CALCIUM-CHANNEL | CA2+-DEPENDENT INACTIVATION | REVEALS
Journal Article
Nature, ISSN 0028-0836, 06/2012, Volume 486, Issue 7403, pp. 405 - 409
Journal Article
Nature Reviews Gastroenterology & Hepatology, ISSN 1759-5045, 02/2011, Volume 8, Issue 2, pp. 108 - 118
Journal Article
ANESTHESIOLOGY, ISSN 0003-3022, 12/2019, Volume 131, Issue 6, pp. 1276 - 1291
Background: Transgenic mouse studies suggest that gamma-aminobutyric acid type A (GABA(A)) receptors containing beta 3 subunits mediate important effects of... 
ETOMIDATE | CLEFT-PALATE | GABA(A) RECEPTOR | THIGMOTAXIS | SENSITIVITY | SITES | ANESTHESIOLOGY | IDENTIFICATION | GENERAL-ANESTHESIA | BETA SUBUNIT | MICE LACKING
Journal Article
Journal Article
PLOS ONE, ISSN 1932-6203, 09/2017, Volume 12, Issue 9
Recombinant human follicle-stimulating hormone (r-hFSH) is widely used in fertility treatment. Although biosimilar versions of r-hFSH (follitropin alfa) are... 
HUMAN FSH | HETEROGENEITY | GLYCOPEPTIDE ANALYSIS | CONSISTENCY | PROFILES | MULTIDISCIPLINARY SCIENCES | GONADOTROPINS | MASS | OVARIAN STIMULATION | GLYCOPROTEIN HORMONES | BETA-SUBUNIT
Journal Article