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TRANSLATIONAL ONCOLOGY, ISSN 1936-5233, 04/2018, Volume 11, Issue 2, pp. 358 - 365
Class III ss-tubulin (TUBB3) overexpression in ovarian cancer (OC) associates with poor prognosis. We investigated whether TUBB3 overexpression elicited... 
BETA-TUBULIN | OVEREXPRESSION | ONCOLOGY | RESISTANCE
Journal Article
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 03/2013, Volume 368, Issue 12, pp. 1101 - 1110
Background The excision repair cross-complementation group 1 (ERCC1) protein is a potential prognostic biomarker of the efficacy of cisplatin-based... 
ADJUVANT CHEMOTHERAPY | SURVIVAL | TRIAL | MEDICINE, GENERAL & INTERNAL | COMPLEMENTATION GROUP 1 | MESSENGER-RNA EXPRESSION | VALIDATION | MONOCLONAL-ANTIBODIES | IMMUNODETECTION | CARCINOMA | III BETA-TUBULIN
Journal Article
by Guo, QQ and Luo, Y and Zhai, SY and Jiang, ZL and Zhao, CZ and Xu, JR and Wang, L
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 07/2019, Volume 17, Issue 25, pp. 6201 - 6214
We have recently reported computational models for prediction of cell-based anticancer activity using machine learning methods. Herein, we have developed an... 
BETA-TUBULIN | CHEMISTRY, ORGANIC | INHIBITORS | FORCE-FIELDS | BINDING | PERFORMANCE
Journal Article
Trends in Cell Biology, ISSN 0962-8924, 2014, Volume 25, Issue 3, pp. 125 - 136
Journal Article
Current Opinion in Cell Biology, ISSN 0955-0674, 02/2019, Volume 56, pp. 102 - 108
Cellular microtubules are mosaic polymers assembled from multiple αβ-tubulin isoforms bearing chemically diverse posttranslational modifications. This tubulin... 
BETA-TUBULIN | TRANSPORT | BIOGENESIS | ACETYLATION | PHOSPHORYLATION | ISOTYPES | DYNAMICS | POSTTRANSLATIONAL MODIFICATIONS | POLYMERIZATION | DRIVEN | CELL BIOLOGY | Tubulins | Cells
Journal Article
Biophysical Journal, ISSN 0006-3495, 06/2019, Volume 116, Issue 12, pp. 2240 - 2245
A paradigm shift for models of MT assembly is suggested by a recent cryo-electron microscopy study of microtubules (MTs). Previous assembly models have been... 
CELL-DIVISION | GTP | COMPLEX | ALPHA-BETA-TUBULIN | FILAMENTS | BIOPHYSICS | DIMER | DIVISION PROTEIN FTSZ | POLYMERIZATION | MODEL
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2018, Volume 61, Issue 4, pp. 1704 - 1718
We report the design, synthesis, and biological evaluation of heterocyclic-fused pyrimidines as tubulin polymerization inhibitors targeting the colchicine... 
CANCER-CELLS | METASTATIC MELANOMA | CHEMISTRY, MEDICINAL | TAXANE RESISTANCE | PACLITAXEL RESISTANCE | TUMOR-VASCULATURE | ANTICANCER AGENTS | VASCULAR-DISRUPTING AGENTS | MICROTUBULE DESTABILIZING AGENT | BIOLOGICAL EVALUATION | III BETA-TUBULIN
Journal Article