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Journal Article
FRONTIERS IN MICROBIOLOGY, ISSN 1664-302X, 05/2019, Volume 10, p. 1047
Journal Article
Analytical Chemistry, ISSN 0003-2700, 09/2015, Volume 87, Issue 18, pp. 9186 - 9193
Host cell proteins (HCPs) are bioprocess-related impurities arising from cell-death or secretion from nonhuman cells used for recombinant protein production.... 
CHEMISTRY, ANALYTICAL | MECHANISM | QUANTIFICATION | DYNAMICS | ARGININE | BIOTHERAPEUTICS | MONOCLONAL-ANTIBODIES | IDENTIFICATION | IMPURITIES | CAPTURE | HCPS
Journal Article
Glycoconjugate Journal, ISSN 0282-0080, 2/2017, Volume 34, Issue 1, pp. 95 - 105
The site-specific quantitation of N- and O-glycosylation is vital to understanding the function(s) of different glycans expressed at a given site of a protein... 
Life Sciences | Biochemistry, general | Pathology | Quantitative glycoproteomics | 18 O–labeling and biotherapeutics | Glycopeptide | Mass spectrometry | O–labeling and biotherapeutics
Journal Article
by Qu, Jun
Bioanalysis, ISSN 1757-6180, 03/2018, Volume 10, Issue 6, pp. 375 - 376
Jun Qu speaks to Sankeetha Nadarajah, Editor of Bioanalysis: Jun Qu is the group leader of the proteomics and pharmaceutical analysis lab of SUNY-Buffalo (NY,... 
proteomics | bioanalysis | LC-MS; biotherapeutics | pharmaceutical analysis | biotherapeutics | CHEMISTRY, ANALYTICAL | LC-MS | BIOCHEMICAL RESEARCH METHODS
Journal Article
Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 01/2020, Volume 178, p. 112892
•Multicapillary gel electrophoresis of partitioned N-glycan libraries for GU database generation.•Analysis of 12 samples in 10 min.•Identification of the... 
Capillary electrophoresis | Biotherapeutics | Glycans | CHEMISTRY, ANALYTICAL | PHARMACOLOGY & PHARMACY
Journal Article
Regulatory Toxicology and Pharmacology, ISSN 0273-2300, 02/2020, Volume 110, p. 104525
Biotherapeutics dominate the pipelines of pharmaceutical companies across the world today with products ranging from hormones, immune-modulators, monoclonal... 
Biosimilars | Regulatory framework | Affordable biotherapeutics | Developed economies | MEDICINE, LEGAL | PHARMACOLOGY & PHARMACY | TOXICOLOGY
Journal Article
Small, ISSN 1613-6810, 11/2019, Volume 15, Issue 46, pp. 1970247 - n/a
In article number 1902393, Charles G. Knutson, Roger D. Kamm, and co‐workers use microvascular networks self‐assembled from human cells within microfluid... 
transendothelial transport | hydraulic conductivity | biotherapeutics and biologics | organ‐on‐chip | permeability | Cell membranes | Fluid dynamics | Transport | Fluid flow
Journal Article
Therapeutic Delivery, ISSN 2041-5990, 11/2017, Volume 8, Issue 11, pp. 947 - 956
Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new... 
biotherapeutics | natural products | drug discovery | drug-delivery systems | Index Medicus
Journal Article
Toxicologic Pathology, ISSN 0192-6233, 06/2010, Volume 38, Issue 4, pp. 522 - 553
An important safety consideration for developing new therapeutics is assessing the potential that the therapy will increase the risk of cancer. For... 
Biotherapeutics | Safety assessment | Carcinogenicity | Regulatory toxicology
Journal Article
Toxicological Sciences, ISSN 1096-6080, 10/2016, Volume 153, Issue 2, pp. 258 - 270
Protein aggregation is associated with enhanced immunogenicity of biotherapeutics. As a result, regulatory guidelines recommend screening for aggregation... 
Protein aggregation | OVA | Immunogenicity | Biotherapeutic | ScFv | MURINE MONOCLONAL-ANTIBODY | TH2 RESPONSES | SUSCEPTIBILITY | BIOTHERAPEUTICS | INTERFERON-BETA | immunogenicity | biotherapeutic | BALB/C MICE | FRAGMENTS | IMPACT | scFv | protein aggregation | IMMUNE-RESPONSES | MOUSE MODEL | TOXICOLOGY
Journal Article
Toxicologic Pathology, ISSN 0192-6233, 2/2019, Volume 47, Issue 2, pp. 165 - 173
Biotherapeutics are pharmaceutical products derived from or synthesized by biological systems. Such molecules carry the potential for immunogenicity which may... 
biotherapeutics | immune reaction | cynomolgus | CNS (central nervous system) | nonhuman primate | CHOROID-PLEXUS | TOXICOLOGY | IMMUNE-SURVEILLANCE | PATHOLOGY
Journal Article
FEMS Microbiology Letters, ISSN 0378-1097, 10/2019, Volume 366, Issue Supplement_1, pp. i30 - i41
ABSTRACT This mini-review provides a perspective of traditional, emerging and future applications of lactic acid bacteria (LAB) and how genome editing tools... 
Journal Article
Journal of Immunological Methods, ISSN 0022-1759, 11/2019, Volume 474, p. 112666
Identity testing of biopharmaceutical products is conducted at multiple steps in the manufacturing process, for drug product lot release, and often for product... 
Validation | Biotherapeutics | Lateral flow | Monoclonal antibody | Identity testing | CELLS | BIOCHEMICAL RESEARCH METHODS | IMMUNOLOGY | ANTIBODY THERAPY
Journal Article
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