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Journal of Pharmaceutical Sciences, ISSN 0022-3549, 04/2019, Volume 108, Issue 4, pp. 1619 - 1626
This study investigated the mechanism of transporting imperatorin across the inner blood-retinal barrier (iBRB). The carotid artery single injection method was... 
blood-retinal barrier (BRB) | carrier-mediated transporter | imperatorin | in vitro | in vivo | in vivo | in vitro | CHEMISTRY, MEDICINAL | ORGANIC CATION TRANSPORTER | VIVO | INVOLVEMENT | CHEMISTRY, MULTIDISCIPLINARY | BRAIN-BARRIER | CLONIDINE | IN-VITRO | CHOLINE TRANSPORT | DRUGS | PHARMACOLOGY & PHARMACY | ANTIPORTER | FURANOCOUMARINS
Journal Article
Experimental Eye Research, ISSN 0014-4835, 09/2019, Volume 186, p. 107686
The blood retinal barrier (BRB) closely regulates the retinal microenvironment. Its compromise leads to the accumulation of retinal fluid containing... 
Complement factor 9 (C9) | Age-related macular degeneration (AMD) | Fibrinogen | Blood retinal barrier (BRB) | Albumin | IgG | Retina | Iron | COMPLEMENT | BARRIER BREAKDOWN | POLYMORPHISM | ACTIVE-TRANSPORT | TRANSFERRIN | PIGMENT EPITHELIUM | OPHTHALMOLOGY | MACULAR-DEGENERATION | UP-REGULATION | FLUORESCEIN | BLOOD
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 2014, Volume 37, Issue 5, pp. 817 - 825
Taurine transporter (TauT/SLC6A6) is an "honorary" γ-aminobutyric acid (GABA) transporter because of its low affinity for GABA. The sequence analysis of TauT... 
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2012, Volume 446, Issue 3, pp. 455 - 467
Journal Article
Yakugaku Zasshi, ISSN 0031-6903, 10/2015, Volume 135, Issue 10, pp. 1135 - 1140
Journal Article
Journal Article
Journal Article
YAKUGAKU ZASSHI, ISSN 0031-6903, 2015, Volume 135, Issue 10, pp. 1135 - 1140
Studies of neurological dysfunction have revealed the neuroprotective effect of several cationic drugs, suggesting their usefulness in the treatment of... 
blood-retinal barrier (BRB) | blood-brain barrier (BBB) | membrane transport | cationic drugs | neuroprotective agent | transporter
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 03/2017, Volume 171, pp. 30 - 42
Pericytes are a heterogeneous population of cells located in the blood vessel wall. They were first identified in the 19th century by Rouget, however their... 
Pericytes | Perivascular stem cells | Diabetic retinopathy | Diabetic nephropathy | Pericyte fibrosis | Cancer stem cells | DIABETIC-RETINOPATHY | Cancer stern cells | VEGF-A | BLOOD-BRAIN-BARRIER | MESENCHYMAL STEM-CELLS | EPITHELIUM-DERIVED FACTOR | HIGH GLUCOSE | PHARMACOLOGY & PHARMACY | STROMAL CELLS | TUMOR-GROWTH | GLYCATION END-PRODUCTS | ENDOTHELIAL GROWTH-FACTOR | Neoplasms - therapy | Animals | Diabetes Mellitus - physiopathology | Vascular Diseases - therapy | Diabetes Mellitus - therapy | Humans | Pericytes - cytology | Ischemia - therapy | Vascular Diseases - physiopathology | Ischemia - physiopathology | Molecular Targeted Therapy | Neoplasms - pathology | Blood circulation disorders | Therapeutics | Homeopathy | Materia medica and therapeutics | Impotence | Diabetic nephropathies | T cells | Muscle proteins | Cardiovascular agents | Blood coagulation factor VIII | Interleukins | Chronic kidney failure | Type 1 diabetes | Stem cells | Vascular endothelial growth factor | Mitogens | Protein kinases | Growth factors | UUO, unilateral ureteric obstruction | EGFR, EGF receptor | EMT, epithelial-mesenchymal transition | SFT, solitary fibrous tumour | DAN, diabetic autonomous neuropathy | ECM, extracellular matrix | NRF2, nuclear factor (erythroid-derived 2)-like 2 | IL-6, interleukin 6 | PSC, perivascular stem cell | BBB, blood-brain barrier | SOD, super oxide dismutase | HIF, hypoxia inducible factor | ED, erectile dysfunction | SDF-1, stromal derived factor 1 | RAGE, receptors of AGEs | CKD, chronic kidney disease | MMP, matrix metalloproteinases | MDSC, myeloid-derived suppressor cells | DN, diabetic nephropathy | TGF β, transforming growth factor β | PDL-1, programmed death-ligand 1 | ANG2, angiopoietin-2 | Olmfl3, Olfactomedin-like 3 | VEGF, vascular endothelial growth factor | AGE, Advanced Glycation End-Products | EC, endothelial cells | NG2, neural | R, ischemia-reperfusion | MSC, mesenchymal stromal cell | MF-EGF8, milk fat globule epidermal growth factor VIII | IL-8, interleukin 8 | glial antigen 2 | T1D, type 1 diabetic | PDGFb, platelet-derived growth factor B | MAPK, mitogen-activated protein kinase | PDGFRβ, platelet derived growth factor receptor β | DR, diabetic retinopathy | CNS, blood-retinal barrier | HB-EGF, heparin-binding EGF-like growth factor | HPC, hemangiopericytoma | PDR, proliferative diabetic retinopathy | DME, diabetic macular oedema | GFR, glomerular filtration rate | MI, myocardial infarction | SMA, smooth muscle actin | CSC, cancer stem cell | NPDR, non-proliferative diabetic retinopathy | T2D, type 2 diabetic | ROS, reactive oxygen species | Treg, regulatory T cells | BRB, blood-retina barrier | PKC, protein kinase C | DPN, diabetic peripheral neuropathy | TME, tumour microenvironment | ANG1, angiopoietin-1 | GSC, glioblastoma CSC | iPS, induced pluripotent stem cells | GSI, g-secretase inhibitor | FGF-9, fibroblastic growth factor 9 | PEDF, Pigment Epithelium-Derived Factor
Journal Article