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1. Full Text Effect of Humeral Head Defect Size on Glenohumeral Stability
: A Cadaveric Study of Simulated Hill-Sachs Defects
by Kaar, Scott G and Fening, Stephen D and Jones, Morgan H and Colbrunn, Robb W and Miniaci, Anthony
The American Journal of Sports Medicine, ISSN 0363-5465, 3/2010, Volume 38, Issue 3, pp. 594 - 599
Background Hill-Sachs lesions are often present with recurrent shoulder instability and may be a cause of failed Bankart repair. Hypothesis Glenohumeral joint... 
dislocation | shoulder instability | Hill-Sachs | Bankart repair | GLENOID DEFECT | SPORT SCIENCES | STABILIZATION | MODEL | LESION | FAILURE | RECURRENT ANTERIOR DISLOCATION | BONE LOSS | ORTHOPEDICS | Biomechanical Phenomena | Humans | Range of Motion, Articular | Rotator Cuff - physiopathology | Humerus - injuries | Bursitis - physiopathology | Joint Instability - physiopathology | Cadaver | Shoulder Dislocation - physiopathology | Shoulder joint | Abnormalities | Research | Humerus | Hypermobility | Joints | Dislocation
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2. Full Text Porous Poly(ϵ-caprolactone)-Poly(l-lactic acid) Semi-Interpenetrating Networks as Superior, Defect-Specific Scaffolds with Potential for Cranial Bone Defect Repair
by Woodard, Lindsay N and Kmetz, Kevin T and Roth, Abigail A and Page, Vanessa M and Grunlan, Melissa A
Biomacromolecules, ISSN 1525-7797, 12/2017, Volume 18, Issue 12, pp. 4075 - 4083
The treatment of irregular cranial bone defects is currently limited due to the graft resorption that can occur when an ill-fitting interface exists between an... 
L-LACTIDE | POLYMER SCIENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SHAPE-MEMORY POLYMERS | CROSS-LINKING | CHEMISTRY, ORGANIC | MECHANICAL-PROPERTIES | IN-VITRO | TISSUE ENGINEERING APPLICATIONS | EPSILON-CAPROLACTONE | ALIPHATIC POLYESTERS | POLY(LACTIC ACID) | BIOMEDICAL APPLICATIONS | Tissue Scaffolds | Polyesters - chemistry | Bone and Bones - physiopathology | Skull - physiopathology | Bone Diseases - therapy | Tissue Engineering - methods | Humans | Polymers - chemistry | Porosity
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3. Full Text Murine Rankl−/− Mesenchymal Stromal Cells Display an Osteogenic Differentiation Defect Improved by a RANKL‐Expressing Lentiviral Vector
by Schena, Francesca and Menale, Ciro and Caci, Emanuela and Diomede, Lorenzo and Palagano, Eleonora and Recordati, Camilla and Sandri, Monica and Tampieri, Anna and Bortolomai, Ileana and Capo, Valentina and Pastorino, Claudia and Bertoni, Arinna and Gattorno, Marco and Martini, Alberto and Villa, Anna and Traggiai, Elisabetta and Sobacchi, Cristina
STEM CELLS, ISSN 1066-5099, 05/2017, Volume 35, Issue 5, pp. 1365 - 1377
Autosomal recessive osteopetrosis (ARO) is a severe bone disease characterized by increased bone density due to impairment in osteoclast resorptive function or... 
Rankl | Mesenchymal stromal cell | Osteopetrosis | Bone | Differentiation | Lentiviral transduction | STEM-CELLS | HOMEOSTASIS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | OSTEOCLASTOGENESIS | IN-VITRO | GENE | ONCOLOGY | HUMAN BONE-MARROW | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | FACTOR FAMILY-MEMBER | MUTATIONS | HEMATOLOGY | SKELETAL DEVELOPMENT | Biomarkers - metabolism | RANK Ligand - metabolism | Transduction, Genetic | Signal Transduction | Mice, Inbred C57BL | Genetic Vectors - metabolism | Mesenchymal Stromal Cells - metabolism | Immunophenotyping | Lentivirus - metabolism | Mesenchymal Stromal Cells - cytology | Animals | RANK Ligand - deficiency | Cell Differentiation | Clone Cells | Osteogenesis | Bones | Transplantation | Cell differentiation | Density | Hematopoietic stem cells | Rodents | Defects | Mesenchyme | Stem cell transplantation | Osteoblasts | Hemopoiesis | Osteoclastogenesis | Stromal cells | Stem cells | Bone marrow | Mice | Bone density | Autocrine signalling | TRANCE protein
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4. Full Text Controversies in orbital reconstruction—I. Defect-driven orbital reconstruction: A systematic review
by Dubois, L and Steenen, S.A and Gooris, P.J.J and Mourits, M.P and Becking, A.G
International Journal of Oral & Maxillofacial Surgery, ISSN 0901-5027, 2014, Volume 44, Issue 3, pp. 308 - 315
Abstract In the 1980s, computed tomography was introduced as an imaging modality for diagnosing orbital fractures. Since then, new light has been shed on the... 
Surgery | Orbital fractures | Orbit | Orbital reconstruction | Indication | Trauma | Classification of facial fractures | SURGERY | CARTILAGE GRAFT | FLOOR FRACTURES | REPAIR | BONE-GRAFT | RECOMMENDATIONS | DENTISTRY, ORAL SURGERY & MEDICINE | MAXILLARY SINUS | NONSURGICAL MANAGEMENT | WALL DEFECTS | PROLAPSE | POLYDIOXANONE | Orbital Fractures - diagnostic imaging | Orbital Fractures - surgery | Tomography, X-Ray Computed | Humans | Reconstructive Surgical Procedures - methods
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5. Full Text Multiple organ system defects and transcriptional dysregulation in the Nipbl+/- mouse, a model of Cornelia de Lange syndrome
by Kawauchi, Shimako and Calof, Anne L and Santos, Rosaysela and Lopez-Burks, Martha E and Young, Clint M and Hoang, Michelle P and Chua, Abigail and Lao, Taotao and Lechner, Mark S and Daniel, Jeremy A and Nussenzweig, Andre and Kitzes, Leonard and Yokomori, Kyoko and Hallgrimsson, Benedikt and Lander, Arthur D
PLoS Genetics, ISSN 1553-7390, 09/2009, Volume 5, Issue 9, p. e1000650
Cornelia de Lange Syndrome (CdLS) is a multi-organ system birth defects disorder linked, in at least half of cases, to heterozygous mutations in the NIPBL... 
SISTER-CHROMATID COHESION | CONTROL REGION | ENHANCER-BLOCKING ACTIVITY | NIPPED-B | CONGENITAL HEART-DISEASE | GENETICS & HEREDITY | GENE-EXPRESSION | ADIPOCYTE DIFFERENTIATION | OPHTHALMOLOGIC FINDINGS | BRACHMANN-DELANGE SYNDROME | MICE LACKING | Bone and Bones - pathology | Cadherins - metabolism | Craniofacial Abnormalities - physiopathology | Heart Defects, Congenital - genetics | Organ Specificity - genetics | Nervous System Malformations - physiopathology | Sister Chromatid Exchange | Craniofacial Abnormalities - pathology | Transcription, Genetic | Cadherins - genetics | Nervous System Malformations - genetics | Craniofacial Abnormalities - complications | Craniofacial Abnormalities - genetics | De Lange Syndrome - genetics | Disease Models, Animal | Animals, Newborn | Embryo, Mammalian - pathology | De Lange Syndrome - physiopathology | Gene Expression Regulation | Heart Defects, Congenital - pathology | Bone Development | Transcription Factors - genetics | Mutation - genetics | Embryo, Mammalian - abnormalities | Phenotype | Animals | Heart Defects, Congenital - complications | Nervous System Malformations - complications | Survival Analysis | De Lange Syndrome - complications | Heterozygote | Heart Defects, Congenital - physiopathology | Mice | Bone and Bones - abnormalities | De Lange Syndrome - pathology | Proteins | Video recordings | Colleges & universities | Birth defects | Mutation | Behavior | Experiments | Chromosomes | DNA repair
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6. Full Text A dual functional bone‐defect‐filling material with sequential antibacterial and osteoinductive properties for infected bone defect repair
by Wang, Dongyun and Liu, Yi and Liu, Yuelian and Yan, Liang and Zaat, Sebastian A.J and Wismeijer, Daniel and Pathak, Janak L and Wu, Gang
Journal of Biomedical Materials Research Part A, ISSN 1549-3296, 10/2019, Volume 107, Issue 10, pp. 2360 - 2370
Infected bone defect healing is hindered by infection and compromised bone regenerative capacity. In this study, we designed a dual functional... 
antibacterial activity | bone morphogenic protein 2 | infected bone defect healing | osteoinductivity | hydroxypropyltrimethyl ammonium chloride chitosan | QUATERNIZED CHITOSAN | ANTIBIOTICS | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | REGENERATION | RIDGE PRESERVATION | DELIVERY | PMMA | COATINGS | SCAFFOLDS | CYTOTOXICITY | Methicillin | Ammonium compounds | Bone morphogenetic proteins | Calcium phosphate | Phosphatases | Ammonium paratungstate | Alkaline phosphatase | Ammonium | Osteocalcin | Bone morphogenetic protein 2 | Calcium | Bone healing | Antibacterial materials | Ammonium chlorides | Calcium phosphates | Defects | Bone resorption | Ammonium chloride | Bone growth | Biomedical materials | Biomimetics | Mineralization | Bone | Chitosan | Repair | Controlled release | Osteogenesis
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7. Full Text Infection and tissue engineering in segmental bone defects — a mini review
by Nair, Manitha B and Kretlow, James D and Mikos, Antonios G and Kasper, F Kurtis
Current Opinion in Biotechnology, ISSN 0958-1669, 2011, Volume 22, Issue 5, pp. 721 - 725
Research highlights ► We review osteomyelitis and implants for local antibiotic delivery to address it. ► We highlight a need for a system to eliminate... 
Internal Medicine | ANGIOGENESIS | DRUG-DELIVERY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | LOCAL ANTIBIOTIC DELIVERY | BIOCHEMICAL RESEARCH METHODS | RAT FEMUR | DEVICES | PMMA BEADS | MORPHOGENETIC PROTEINS | RELEASE | MODEL | CHRONIC OSTEOMYELITIS | Osteomyelitis - therapy | Animals | Osteomyelitis - pathology | Biocompatible Materials | Models, Animal | Bone Regeneration | Bone and Bones - cytology | Tissue Engineering | Tissue engineering | Health aspects | Analysis
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8. Advances in defect removal techniques
: a teleconferencing workshop held February 25, 1992
by Gushue, J and Canadian Centre for Fisheries Innovation and Canada. Industry, Science and Technology Canada. Seafood and Marine Products Sector Campaign
1992, [13] leaves.
Canada | bones | parasites | processing fishery products | inspection
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9. Full Text Effect of an Anterior Glenoid Defect on Anterior Shoulder Stability
: A Cadaveric Study
by Yamamoto, Nobuyuki and Itoi, Eiji and Abe, Hidekazu and Kikuchi, Kazuma and Seki, Nobutoshi and Minagawa, Hiroshi and Tuoheti, Yilihamu
The American Journal of Sports Medicine, ISSN 0363-5465, 5/2009, Volume 37, Issue 5, pp. 949 - 954
Background There have been few biomechanical studies to clarify which size of a glenoid defect is critical. However, those studies have assumed that the defect... 
Surgical indication | Anterior shoulder instability | Bankart lesion | Glenoid depth | Glenoid bone loss | SPORT SCIENCES | surgical indication | CONCAVITY | GLENOHUMERAL INSTABILITY | RECONSTRUCTION | glenoid depth | BANKART REPAIR | CT | BONE LOSS | DISLOCATION | glenoid bone loss | OUTCOMES | ORTHOPEDICS | JOINT | anterior shoulder instability | Biomechanical Phenomena | Shoulder Joint - physiopathology | Humans | Range of Motion, Articular | Female | Male | Aged | Joint Instability - physiopathology | Shoulder Dislocation - physiopathology | Shoulder surgery | Physiological aspects | Shoulder joint | Research | Patient outcomes
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10. Full Text Monocytes from Irf5 -/- mice have an intrinsic defect in their response to pristane-induced lupus
by Yang, Lisong and Feng, Di and Bi, Xiaohui and Stone, Rivka C and Barnes, Betsy J
Journal of Immunology, ISSN 0022-1767, 10/2012, Volume 189, Issue 7, pp. 3741 - 3750
The transcription factor IFN regulatory factor (IRF)5 has been identified as a human systemic lupus erythematosus (SLE) susceptibility gene by numerous joint... 
RECRUITMENT | ACTIVATION | INCREASED RISK | ERYTHEMATOSUS SLE | IRF5 | INDUCTION | IMMUNOLOGY | MOUSE BONE-MARROW | INTERFERON REGULATORY FACTOR | I INTERFERON | BLOOD-CELLS | Peritoneal Cavity - pathology | Humans | Mice, Inbred C57BL | Interferon Regulatory Factors - genetics | Monocytes - metabolism | Terpenes - toxicity | Monocytes - immunology | Interferon Regulatory Factors - deficiency | Mice, Knockout | Cell Movement - immunology | Animals | Antigens, Ly - biosynthesis | HEK293 Cells | Lupus Erythematosus, Systemic - immunology | Monocytes - pathology | Interferon Regulatory Factors - physiology | Lupus Erythematosus, Systemic - chemically induced | Mice | Lupus Erythematosus, Systemic - pathology
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11. Full Text Bone regeneration in dehiscence‐type defects at chemically modified (SLActive®) and conventional SLA titanium implants: a pilot study in dogs
by Schwarz, Frank and Herten, Monika and Sager, Martin and Wieland, Marco and Dard, Michel and Becker, Jürgen
Journal of Clinical Periodontology, ISSN 0303-6979, 01/2007, Volume 34, Issue 1, pp. 78 - 86
Objectives: The aim of the present study was to evaluate bone regeneration in dehiscence‐type defects at titanium implants with chemically modified (mod) and... 
sand‐blasted and acid‐etched surface | titanium surface | animal study | histomorphometrical analysis | dehiscence‐type defect | Dehiscence-type defect | Sand-blasted and acid-etched surface | Titanium surface | Animal study | Histomorphometrical analysis | CELLS | MATRIX | DENTAL IMPLANTS | MARROW | MEMBRANES | sand-blasted and acid-etched surface | LONG-TERM EVALUATION | DENTISTRY, ORAL SURGERY & MEDICINE | dehiscence-type defect | SURFACE | APPOSITION | LIFE TABLE ANALYSIS | EXPRESSION | Bone Regeneration - physiology | Osteogenesis - physiology | Connective Tissue - pathology | Alveolar Process - pathology | Osseointegration - physiology | Titanium - chemistry | Coated Materials, Biocompatible - chemistry | Bone Remodeling - physiology | Random Allocation | Alveolar Bone Loss - pathology | Pilot Projects | Animals | Dental Materials - chemistry | Time Factors | Connective Tissue - physiopathology | Surface Properties | Dogs | Alveolar Bone Loss - physiopathology | Dental Implants | Acid Etching, Dental | Dental Implantation, Endosseous - methods | Air Abrasion, Dental | Alveolar Process - physiopathology | Implants, Artificial | Prosthesis | Analysis
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12. Full Text β -TCP bone graft substitutes in a bilateral rabbit tibial defect model
by Walsh, William R and Vizesi, Frank and Michael, Dean and Auld, Jason and Langdown, Andy and Oliver, Rema and Yu, Yan and Irie, Hiroyuki and Bruce, Warwick
Biomaterials, ISSN 0142-9612, 2007, Volume 29, Issue 3, pp. 266 - 271
Abstract The use of artificial bone graft substitutes has increased as the surgical applications widen and the availability of allograft bone decreases. The... 
Advanced Basic Science | Dentistry | Tricalcium phosphate |